Clinical trials: Neurological Conditions
Postoperative Pain
Evaluation of Smartphone Versions of VAS and NRS for Use in Adults
A large number of patients experience significant pain after surgery, and more patients report pain after discharge from hospital than before.
- Trial name
- Panda (NCT04139590)
- Testing
- Panda, Visual Analogue Scale - Original
- Where
- 2 sites in Canada
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Low Back Pain
Study to Evaluate the Effectiveness of Orthopedic Spinal Supports in the Treatment of Low Back Pain
The purpose of this study is to determine whether orthopedic spinal supports are effective in the treatment of low back pain.
- Trial name
- NCT00553540
- Testing
- Back supports
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cleveland Clinic Florida
Sleep Deprivation, Obesity
Effects of Sleep Restriction on BAT Activation in Humans
The goal of this proposed research is to test the hypothesis that long-term mild sleep restriction (SR), as occurs frequently in adults and adolescents, leads to a positive energy balance and weight gain. Aim 1.
- Trial name
- BAT (NCT02770118)
- Testing
- Partial Sleep Restriction, Total Sleep Deprivation, Habitual Sleep
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Columbia University
Sarcopenia, Osteoporosis
Ibuprofen Supplementation After Resistance Training and Its Effects on Bone in Older Women
Inflammation increases with aging and is implicated in the reduction of bone mass, muscle mass, and strength. Resistance training is safe and effective for increasing muscle mass and strength in older adults,however resistance…
- Trial name
- NCT01886196
- Testing
- Non-steroidal anti-inflammatory drug (Ibuprofen), Resistance exercise, Flexibility training
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Major Depressive Disorder
Brain Regulation of Emotions in People With Depression and Anhedonia
This study will use magnetic resonance imaging (MRI) to examine how the brain regulates emotions in healthy people and in patients who have major depression and anhedonia (loss of feeling of pleasure in things that normally give…
- Trial name
- NCT00059579
- Where
- United States
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Post Herpetic Neuralgia, Herpes Zoster
Treatment of Chronic Postherpetic Pain With Fat Grafting
This study evaluates the possible beneficial effect of fat grafting for post herpetic neuralgia.
- Trial name
- NCT03584061
- Testing
- Fat grafting
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Muscle Synthesis
Effects of Protein Blends on Muscle Protein Synthesis in Healthy Older Adults
During aging there is a tendency for muscle protein synthesis (growth) to become less efficient and the resulting consequence leads to reduced muscle mass (sarcopenia) which can affect strength and mobility.
- Trial name
- NCT01847261
- Testing
- Soy Dairy Protein Blend, Positive Control (Dairy Whey Protein)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DuPont Nutrition and Health
Post Operative Pain, Chronic Apical Periodontitis of Pulpal Origin
The Effect of Using Reciprocal Files Alone and With Different Files on Postoperative Pain
This study aims to investigate the effects of using the Wave One Gold file alone and in combination with different files on postoperative pain in patients with asymptomatic apical periodontitis.
- Trial name
- NCT06833515
- Testing
- one flare+wave one gold glider+wave one gold, wave one gold glider+wave one gold, wave one gold
- Where
- Turkey (Türkiye)
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Harran University
Labor Pain
Intrathecal Analgesia for Normal Labour
Primary outcome: Compare the duration of analgesia. Secondary outcome: analgesic potency of bupivacaine and fentanyl versus levobupivacaine and fentanyl.
- Trial name
- NCT04221568
- Testing
- Bupivacaine-fentanyl, levobupivacaine-fentanyl
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postoperative Pain
Ice Application for Postoperative Pain
The purpose of the proposed study is to investigate the effectiveness of cryotherapy as an additional form of pain control in women undergoing laparoscopic hysterectomy for benign gynecologic conditions through a randomized trial.
- Trial name
- Ice-POP (NCT04145791)
- Testing
- Ice
- Where
- 2 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Memory Impairment
Memory and Exercise Training Study in Older Adults With Subjective Memory Complaints
This pilot study is a first step in a rapidly growing area of clinical research to create the most effective means to combat age-related losses in cognitive function through preventive lifestyle strategies such as physical…
- Trial name
- MET (NCT02433691)
- Testing
- simultaneous aerobic exercise, sequential aerobic exercise, stretching and toning
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- David Merrill, MD, PhD
Stunting, Underweight
Spirulina Supplementation and Infant Growth, Morbidity and Motor Development
Background: In developing countries, micronutrient deficiency in infants is associated with growth faltering, morbidity, and delayed motor development.
- Conditions
- Stunting, Underweight, Pneumonia, Pneumocystis, Cough
- Trial name
- NCT03523182
- Testing
- Spirulina, Control
- Where
- Zambia
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Programme Against Malnutrition
Anxiety, Pain
Effect of Virtual Reality on Anxiety and Pain During Gynecological Examination
This randomized controlled trial aims to examine the effects of using virtual reality (VR) glasses during gynecological examinations on women's pain and anxiety levels.
- Conditions
- Anxiety, Pain, Gynecological Examination, Women's Health
- Trial name
- VR-GYN (NCT07059780)
- Testing
- Virtual Reality Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Fazilet Nur Daşkın
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
Healthy, Low Back Pain
Lumbar Assistive Exoskeletons in Caregiving
A randomized control trial will be conducted, for evaluating the effectiveness of the implementation of a lower back assistive exoskeleton on the caregivers working in nursing homes.
- Conditions
- Healthy, Low Back Pain, Musculoskeletal Pain, Musculoskeletal Injury
- Trial name
- ExoCare (NCT05473208)
- Testing
- Exoskeleton
- Where
- 2 sites in Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Pain, Postoperative
Addition of Popliteal Plexus Block to Continuous Femoral Nerve Block for Total Knee Arthroplasty
The popliteal plexus block has been described as an alternative analgesic postoperative pain treatment for total knee arthroplasty.
- Trial name
- NCT04048889
- Testing
- Ropivacaine 0.5% Injectable Solution
- Where
- Switzerland
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Burning Mouth Syndrome
Opiorphin Levels in Fluids of Burning Mouth Syndrome Patients (OPIODYN)
If epidemiological studies indicate relatively low prevalence reported in the general population, idiopathic burning mouth syndrome (BMS) is a common condition among certain groups of the population: 30% of menopausal women…
- Trial name
- OPIODYN (NCT02686359)
- Testing
- sample
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Pain
Effects of Pain on Driving Performance and Cognition.
It has been suggested that cognitive functioning is impaired in chronic pain patients. Since most of these pain patients engage in daily activities including driving, it was hypothezised that they may have an increased risk of…
- Trial name
- NCT00189046
- Testing
- driving and laboratory tests
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Aphasia, Nonfluent Aphasia
Neural Networks and Language Recovery in Aphasia From Stroke: fMRI Studies
The purpose of this research is to utilize functional magnetic resonance imaging (fMRI) to investigate brain reorganization for language behavior in stroke patients with aphasia.
- Conditions
- Aphasia, Nonfluent Aphasia, Stroke
- Trial name
- NCT00467103
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression, Pain
Paroxetines Effect on Tramadols Metabolism and Pharmakodynamics: a Dose Response Study
The purpose of the study is to examine the connection between the dose of paroxetine and the effect of paroxetine on tramadols metabolism and thereby the effect of tramadol on the median pupil size.
- Trial name
- NCT00785603
- Testing
- Paroxetine, Tramadol
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
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