Clinical trials: Neurological Diseases
Cervical Radiculopathy
Thoracic Manipulation in Patients With Cervical Radiculopathy
Hypothesis: The group of Cervical Radiculopathy patients receiving thoracic thrust manipulation will demonstrate immediate and short term significant clinically important changes in outcomes when compared to the sham manipulation…
- Trial name
- NCT01495728
- Testing
- Thrust Manipulation - Thoracic Spine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Spine and Sport, Georgia
Phantom Limb Pain, Phantom Pain
VR to Evaluate Phantom Limb Pain
The objective of this study is to develop a virtual rehabilitation system that can be used to effectively treat Phantom Limb Pain (PLP) within the research setting and for at-home use by individuals with upper and lower extremity…
- Conditions
- Phantom Limb Pain, Phantom Pain, Phantom Sensation, Phantom Limb Syndrome With Pain
- Trial name
- NCT05915065
- Testing
- Coapt Phantom Limb Pain Management System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab
Anxiety Disorder, Panic Disorder
Vestibular Dysfunction In Adult Patients With Panic Disorder With or Without Agoraphobia
OBJECTIVES: I. Determine whether the prevalence of abnormalities on clinical vestibular (balance) tests is higher in panic disorder with agoraphobia than in uncomplicated panic disorder and nonpanic anxiety disorder. II.
- Trial name
- NCT00004367
- Testing
- Clinical vestibular tests
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Behavioral Dynamics, Visual Impairment
Behavioral Dynamics Between Infants With Visual Loss and Healthy Controls
An individual senses the world and reflects feedbacks via independent behaviors. Such precise collaboration of the sensory and behavioral systems is fundamental to survival and evolution.
- Trial name
- NCT03431207
- Testing
- Standardized video recording for behaviors
- Where
- China
- Volunteers
- 4,196 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Traumatic Brain Injury, Hearing Loss
Improving Speech in Noise Using Noninvasive Stimulation
Traumatic brain injury, a common injury in military service personnel, often leads to poor processing of speech in noisy environments.
- Trial name
- NCT07176936
- Testing
- Cymba Conchae stimulation, Earlobe stimulation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Florida
Diabetic Neuropathies, Diabetes Mellitus
Efficacy and Safety of the Combination of Ten Elements for 6 Months in Patients With Diabetic Neuropathy : A Pilot Study
To investigate the efficacy of Superoxide Dismutase (SOD, 70 UI), Palmitoylethanolamide (PEA, 300 mg) Alpha Lipoic Acid (ALA, 300 mg), vitamins B6 (1.5 mg), B1 (1.1 mg), B12 (2.5 mcg), E (7.5 mg), Nicotinamide (9 mg) and minerals…
- Conditions
- Diabetic Neuropathies, Diabetes Mellitus, Dietary Supplement
- Trial name
- NCT05984771
- Testing
- Epineuron
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aristotle University Of Thessaloniki
Postoperative Pain, Postoperative Nausea and Vomiting (PONV)
Transauricular Vagus Nerve Stimulation Frequencies for Postoperative Pain
The goal of this clinical trial is to learn whether different frequencies of transauricular vagus nerve stimulation (tVNS) can reduce postoperative pain and opioid consumption in adults undergoing abdominal or urologic surgery.
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting (PONV), Opioid Consumption, Postoperative
- Trial name
- TVNS-PAIN (NCT07633444)
- Testing
- Transauricular Vagus Nerve Stimulation (tVNS)
- Where
- Brazil
- Volunteers
- 174 people
- Sponsor
- Federal University of Bahia
Essential Tremor, Parkinson's Disease (PD)
Closed-loop TMS for Tremor
This study investigates the potential of phase-locked transcranial magnetic stimulation (TMS) as a non-invasive intervention for tremor in patients with Essential Tremor (ET) and Parkinson's Disease (PD).
- Trial name
- NCT07574164
- Testing
- TMS
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Fibromyalgia
Montage of HTDCS in Psycho-cognitive Functions in FM
This study aims to map the impact of anodic transcranial direct current stimulation (tDCS) for prolonged home use applied to the primary motor cortex and the left dorsolateral prefrontal córtex (DLPFC), compared to the respective…
- Trial name
- HFTDCS (NCT04890964)
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Tourette Syndrome, Habit Reversal Training
Extinction Learning in Adults With Tourette Syndrome
Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still…
- Conditions
- Tourette Syndrome, Habit Reversal Training, Tic Disorders, Tics
- Trial name
- NCT04498364
- Testing
- Habit Reversal Training
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Dizziness, Cervicogenic Headache
Comparing the Effects of Sub-Occipital Myofascial Release With and Without SNAG on People With Cervicogenic Dizziness.
Cervicogenic dizziness is defined as a sensation of rotation, resulting from an alteration of the neck proprioceptive afferents of the upper cervical spine.Sub-occipital Release, a type of Myofascial Release (MFR) is a form of…
- Trial name
- NCT07062809
- Testing
- Sub Occipital Myofascial release and (SNAGS)., Sub Occipital Myofascial release.
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Postoperative Pain
Levobupivacaine to the Surgical Wound Following Cesarean
The postoperative period following cesarean is associated with moderate to severe pain that requires a considerable amount of analgesics that carry with them side-effects such as nausea, vomiting, fatigue and immobilization.
- Trial name
- NCT01458431
- Testing
- Levobupivacaine, NaCl
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Manuel Ángel Gómez-Ríos
Analgesia
Bilateral Rhomboid Intercostal Block for Perioperative Analgesia in Patients Undergoing Bilateral Reduction Mammoplasty
Bilateral reduction mammoplasty is one of the most commonly performed breast surgery. The Postoperative pain following it should be minimized.
- Trial name
- NCT06225895
- Testing
- general anesthesia, Erector spinae plane block, a rhomboid intercostal nerve block
- Where
- 2 sites in Egypt
- Volunteers
- 72 people
- Sponsor
- Zagazig University
Muscle Relaxants
The Effect of no Muscle Relaxant Versus Reduced-dose Rocuronium on Anesthesia in Adenotonsillectomy
This study aimed to compare the effect of no muscle relaxants and reduced-dose rocuronium on the anesthetic induction and emergence with fentanyl in children undergoing adenotonsillectomy.
- Trial name
- NCT02467595
- Testing
- Rocuronium bromide 0.15 mg kg-1, Rocuronium bromide 0.3 mg kg-1, Fentanyl
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Myalgia
The Effect of Pretreatment With Roc on Succinylcholine Myalgias
Succinylcholine is a medication (depolarizing muscle relaxant) that is used as part of an anesthetic (going to sleep for surgery). This medication can cause significant muscle soreness.
- Trial name
- NCT04581395
- Testing
- non-pretreated Succinylcholine, succinylcholine 1 minute after rocuronium pretreatment, succinylcholine 2 minutes following rocuronium pretreatment
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Indiana University
Carpal Tunnel Syndrome (CTS), Nerve Conduction
Comparative Analysis of Median Nerve Parameters for Carpal Tunnel Syndrome (CTS) Diagnosis: Ultrasound Versus Nerve Conduction Studies (NCS)
Comparative Analysis of Median Nerve Parameters for Carpal Tunnel Syndrome (CTS) Diagnosis: Ultrasound vs. Nerve Conduction Study (NCS) This clinical study aims to determine whether ultrasound can be as practical as NCS in…
- Conditions
- Carpal Tunnel Syndrome (CTS), Nerve Conduction, Ultrasound
- Trial name
- NCT06926777
- Testing
- Nerve Conduction Study
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Combined Military Hospital Kohat Pakistan
Pain, Acute, Emergencies
Inhaled vs IV Opioid Dosing for the Initial Treatment of Severe Acute Pain in the Emergency Department
Prospective single-blind, multicenter, national, randomized, controlled trial in 15 Emergency Department to compare two ways of morphine titration.
- Conditions
- Pain, Acute, Emergencies, Morphine
- Trial name
- CLIN-AEROMORPH (NCT03257319)
- Testing
- inhaled titration of morphine chlorhydrate, IV titration of morphine chlorhydrate
- Where
- 20 sites in France
- Volunteers
- 226 people
- Sponsor
- University Hospital, Rouen
Physical Therapy Modalities
Effects of Physical Therapy Associated With Photobiomodulation on Myelomeningocele
Myelomeningocele is a severe type of spina bifida, resulting from improper closure of the neural tube. This condition drastically affects the structures of the spinal cord, as a result the spinal cord, nerve roots and meninges…
- Trial name
- NCT04425330
- Testing
- physiotherapy exercises, PBM
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Sleep Disorder (Disorder)
US Development and Evaluation Study of a Patch-Based PSG System
The purpose of this study is continue the development and evaluation of the Onera system as well as the procedures and best practices for dispensing, instruction, use and reportability of results.
- Trial name
- NCT06881667
- Testing
- Home PSG Assessment
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Onera BV
Silver Russell Syndrome, Prader-Willi Syndrome
Aromatase Inhibitor in Bone Maturation, Children With Silver Russell or Prader-Willi Syndrome
There is currently no drug with pediatric marketing authorization capable of limiting the advance in bone maturation of children with aggressive adrenarche.
- Trial name
- ANASILPRA (NCT01520467)
- Testing
- Anastrozole
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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