Clinical trials: Neurological Diseases
Eye Pain
Pilot Study of TENS for Ocular Pain
Approximately 20% of Veterans have a diagnosis of dry eye (DE) syndrome which is often accompanied by ocular pain that significantly impacts activities of daily living.
- Trial name
- NCT05531643
- Testing
- High frequency forehead TENS, Low frequency forehead TENS
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- VA Office of Research and Development
Olfactory Disorder
Steroid Nasal Irrigation for Flavor Evaluation and Detection Study
The purpose of this research study is to examine the efficacy of a 12-week smell training intervention for participants with olfactory dysfunction following an infection of the upper respiratory tract.
- Trial name
- SNIFFED (NCT02985515)
- Testing
- Smell training
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Tourette Syndrome
Phase III Randomized, Double-Blind, Placebo-Controlled Study of Guanfacine for Tourette Syndrome and Attention Deficit Hyperactivity Disorder
OBJECTIVES: I. Evaluate the safety and efficacy of the alpha-2 adrenergic agonist guanfacine in children and adolescents with Tourette syndrome or other chronic tic disorder, and attention deficit hyperactivity disorder.
- Trial name
- NCT00004376
- Testing
- guanfacine
- Volunteers
- 35 people
- Sponsor
- National Center for Research Resources (NCRR)
Fibrocystic Disease of Breast
A Study of Topical Danazol for the Treatment of Pain Associated With Fibrocystic Breast Disease
The purpose of this study is to determine the safety of three doses of topically applied danazol compared to placebo in subjects with pain associated with fibrocystic breast disease and to determine the appropriate clinical dose…
- Trial name
- FP1198-001 (NCT00744276)
- Testing
- danazol
- Where
- 30 sites in United States
- Volunteers
- 60 people
- Sponsor
- FemmePharma Global Healthcare, Inc.
Primary Insomnia
Study of the Insomnia in Patients With Low Back Pain
The purpose of this study is to examine whether insomnia due to chronic low back pain can improve with use of eszopiclone.
- Trial name
- NCT00365976
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Duke University
Vitamin D Status, Osteoporosis
Vitamin D Status and Bone Health of Older Adults in Care Facilities
Vitamin D deficiency is proposed to be prevalent in community-dwelling older adults, with prevalence substantially higher among older adults in residential care facilities.
- Conditions
- Vitamin D Status, Osteoporosis, Sarcopenia
- Trial name
- NCT04399291
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Bone Marrow Cancer
The Effect of Relaxing Breathing Exercise Applied to Patients Before Bone Marrow Biopsy on Vital Signs, Pain and Anxiety Levels
There is no study in the literature that determined the effect of relaxing breathing exercise applied to patients before the BMB procedure on vital signs, pain and anxiety levels.
- Trial name
- NCT05632874
- Testing
- relaxing breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Sleep Disorder, Traumatic Brain Injury
Impact of GHRH on Sleep Promotion and Endocrine Regulation in Service Members Who Sustained a Traumatic Brain Injury and Have Current Insomnia
Background: People who have had a traumatic brain injury (TBI) often have trouble sleeping. TBI may also alter hormones, which can cause poor sleep.
- Trial name
- NCT02931474
- Testing
- Tesamorelin
- Sponsor
- National Institute of Nursing Research (NINR)
Pain Management, Satisfaction
Effectiveness of Game-Based Learning in Pain Management Education for Nursing Students
Aim: To evaluate the effectiveness of game-based learning on undergraduate nursing students' pain management knowledge, learning motivation, and educational satisfaction. Background: Pain management is a core nursing competency.
- Conditions
- Pain Management, Satisfaction, Motivation, Knowledge
- Trial name
- NCT07736118
- Testing
- game-based learning
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- TC Erciyes University
Spinal Cord Injuries
Clinical Investigation on Feasibility and Usability of the ABLE Exoskeleton Device for Individuals With Spinal Cord Injury to Perform Skills for Home and Community Environments
The loss of the ability to walk and the associated restriction of mobility presents a major challenge to people with spinal cord injury in an everyday environment designed for pedestrians.
- Trial name
- NCT05643313
- Testing
- ABLE Exoskeleton
- Where
- 2 sites in Germany, Spain
- Volunteers
- 10 people
- Sponsor
- ABLE Human Motion S.L.
Idiopathic Parkinson Disease, Dyskinesias
Reliability and Validity Study of the Turkish Version of the Parkinson's Disease Dyskinesia Scale (PDYS-26)
The aim of this methodological study was to investigate the Turkish validity and reliability of the Parkinson's Disease Dyskinesia Scale (PDYS-26).The scale evaluates choreic dyskinesia.Measures the impact of dyskinesia on…
- Conditions
- Idiopathic Parkinson Disease, Dyskinesias, Quality of Life
- Trial name
- NCT07023224
- Testing
- Turkish version of the Parkinson's Disease Dyskinesia Scale (PDYS-26)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Izmir Bakircay University
Neck Pain, Low Back Pain
Turkish Version of the Usefulness, Satisfaction, and Ease of Use Questionnaire (USE): Reliability and Validity
In recent years, numerous technological products and devices have been developed in rehabilitation through advances in biomedical technology.
- Conditions
- Neck Pain, Low Back Pain, Biomedical Technology, Validation
- Trial name
- NCT07159724
- Testing
- back up, mollii-suit, compex, tens
- Volunteers
- 220 people
- Sponsor
- Hacettepe University
Pain and Anxiety
The Effect of Virtual Reality on Pain and Anxiety During Colposcopic Biopsy: A Randomized Controlled Trial
The study was planned as a prospective, two-arm (1:1) randomized controlled experimental study to determine the effect of virtual reality applied during colposcopic biopsy on pain and anxiety.
- Trial name
- NCT06811259
- Testing
- Virtual reality (in experimental group), Standart care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mersin University
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III All-comers Orsiro Safety and Performance Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- BIOFLOW-III (NCT01553526)
- Where
- 43 sites in Austria, Chile and 11 more
- Volunteers
- 1,356 people
- Sponsor
- Biotronik AG
Posttraumatic Stress Disorder, Chronic Pain
Enhancing Cognitive Processing Therapy for Posttraumatic Stress Disorder Via Stellate Ganglion Block Treatment: A Pilot Trial
Cognitive Processing Therapy (CPT) is an effective first-line, evidence-based treatment for posttraumatic stress disorder (PTSD).
- Trial name
- SGB (NCT05534126)
- Testing
- Stellate Ganglion Block Treatment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Behavioural Problems
Effectiveness of Multisystemic Therapy for Adolescents From Families With Intellectual Disabilities
The goal of this observational study is to determine the effectiveness of a specialisation of multisystemic therapy (MST) for adolescents with severe behavioural problems from families with an intellectual disability (ID…
- Trial name
- NCT06032455
- Testing
- Multisystemic therapy, Multisystemic therapy - intellectual disabilities
- Where
- 4 sites in Netherlands
- Volunteers
- 470 people
- Sponsor
- De Viersprong
Autism Spectrum Disorder, Early Developmental Impairment
Multicenter Validation Study on Autism Screening Using a Machine-assisted System
The goal of this observational study is to assess the effectiveness of a machine-assisted system for early screening of autism. The main questions it aims to answer are: Does the machine-assisted system including 5 main…
- Conditions
- Autism Spectrum Disorder, Early Developmental Impairment, Language Development Disorders
- Trial name
- NCT07006948
- Testing
- Autism Diagnostic Observation Schedule, the 2nd edition(ADOS-2), Griffiths Developmental Scales, Chinese edition(GDS-C)
- Where
- 10 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Usher Syndromes
Natural History Study of Usher Syndrome ( Light4Deaf )
Clinical centres in the LIGHT4DEAF consortium have developed and will continue to improve a reliable, early molecular diagnosis and protocols for full clinical characterisation of Usher syndrome, which will be valuable for the…
- Trial name
- Light4Deaf (NCT04665726)
- Where
- 4 sites in France
- Volunteers
- 400 people
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Parkinson Disease
TUS to Disrupt Pathological Oscillations
Scientists and clinicians are interested in measuring and perturbing the signals in the brain - both to better understand normal operation and explore new therapy options for disease.
- Trial name
- NCT06932185
- Testing
- Transcranial Focussed Ultrasound - Active, Transcranial Focussed Ultrasound - Active control
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Oxford
Chronic Pain, Carpal Tunnel Syndrome
Noninvasive Brain Stimulation for Treating Carpal Tunnel Syndrome
The purpose of this study is to assess the effects of tDCS in combination with TUS for the treatment of pain in subjects with Carpal Tunnel Syndrome.
- Trial name
- NCT04206215
- Testing
- transcranial Direct Current Stimulation (tDCS), Transcranial Ultrasound (TUS)
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Spaulding Rehabilitation Hospital
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