Clinical trials: Neurological Diseases
Autism Spectrum Disorder, Fragile X Syndrome
Speech-in-noise Perception in Autism and Fragile X
The goal of this study is to identify which brain regions are active during speech-in-noise perception, as well as how those regions interact.
- Trial name
- NCT06088589
- Testing
- Mismatch negativity
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Pain Management, Pain After Surgery
Melatonin on Post Operative Pain After CS
The goal of this clinical trial is to learn if melatonin will decrease pain after C.S. The main questions it aims to answer are: Does melatonin lower the number of times participants need to use a rescue analgesia? What medical…
- Conditions
- Pain Management, Pain After Surgery, Cesarean Section Pain
- Trial name
- CS (NCT07380568)
- Testing
- Melatonin 5 mg, Melatonin 10 mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
Virtual Reality
Virtual Realityon Pain, Anxiety and Comfort During Trigger Point Injection
To determine the effects of virtual reality application during trigger point injection on patients' pain, anxiety and comfort levels.This research was planned as a randomized controlled experimental type.
- Trial name
- NCT06140368
- Testing
- virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Izmir Bakircay University
Depression, Bipolar Disorder
Telemedicine for Women With Anhedonia in Bipolar and Unipolar Disorder
Anhedonia, characterized as (a) the diminished motivation to participate in activities, and/or (b) diminished enjoyment of a pleasurable activity are common symptoms among women diagnosed with mood disorders.
- Conditions
- Depression, Bipolar Disorder, Anhedonia
- Trial name
- NCT02494050
- Testing
- Behavioral Activation-Full, Behavioral Activation-Short, Bipolar Disorder Collaborative Care
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Northwestern University
Hemiplegia
Effect of Blood Flow Restriction Training on Quadriceps Muscle Architecture and Functional Abilities in Children With Hemiplegia
This study was done to investigate the effect of blood flow restriction in the lower limbs on: Strength of the quadriceps muscle, quadriceps muscle architecture (muscle thickness and pennation angle between muscle fibres)…
- Trial name
- NCT07648550
- Testing
- the selected physical therapy program, Blood Flow Restriction training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Sciatica, Sciatica Due to Intervertebral Disc Disorder
Transforaminal Epidural Injection in Acute Sciatica
Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery.
- Conditions
- Sciatica, Sciatica Due to Intervertebral Disc Disorder, Sciatic Radiculopathy
- Trial name
- TEIAS (NCT03924791)
- Testing
- Lidocaine, Methylprednisolone Acetate, Dexamethasone
- Where
- 2 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- C.L.A.Vleggeert-Lankamp
Tinnitus
Effectiveness of Cannabis in the Treatment of Tinnitus Patients
The hypothesis of the study is that the use of Cannabis will attenuate the tinnitus level as experienced by the patients.
- Trial name
- NCT01969474
- Testing
- Cannabis
- Where
- Israel
- Sponsor
- Wolfson Medical Center
Chronic Low Back Pain (Non-specific, Uncomplicated)
Telerehabilitation Program to Improve Function in People With Chronic Low Back Pain Compared With Conventional Care
The goal of this clinical trial is to evaluate whether an additional telerehabilitation program, combined with conventional care, can improve functional recovery in adults with chronic low back pain treated in primary care…
- Trial name
- TELEREHAB-LC (NCT07248813)
- Testing
- Telerehabilitation Program, Conventional care
- Where
- Mexico
- Volunteers
- 200 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Delirium, Nurse's Role
Delirium Prevention Guideline for Intensive Care Patients
Delirium is a complication characterized by fluctuations in orientation, memory, thinking, or behavior, with sudden onset of these changes.
- Trial name
- NCT06403410
- Testing
- Delirium Prevention Guideline
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Istanbul Demiroglu Bilim University
Confusion, Inflammation
Confusion in the Elderly After Colon Surgery
A study will be conducted to determine if there is any cognitive benefit in elderly patients having open versus minimally invasive colon cancer surgery.
- Conditions
- Confusion, Inflammation, Acute Phase Reaction, Surgery
- Trial name
- NCT01623297
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- New York Hospital Queens
Sleep Disorder
Sleep Disorders and Quality of Life in Patients With Multiple Sclerosis
1. To determine sleep disturbance in different types of multiple sclerosis. 2. To asses the effect of sleep disturbance on quality of life in patients with multiple sclerosis. 3.
- Trial name
- NCT06012513
- Volunteers
- 60 people
- Sponsor
- Assiut University
Morquio Disease
Establishment of Human Cellular Disease Models for Morquio Disease
Establishment of human cellular disease models for Morquio disease for an individualized therapy development having the capacity to address both hepatic and neurologic forms of the disease
- Trial name
- IPSMORQUIO (NCT03872713)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- CENTOGENE GmbH Rostock
Articulation Disorder, Dysarthria
Evaluating the Efficacy of Opti-Speech for Speech Treatment
The purpose of this study is to determine if feedback from a three-dimensional real-time visualization of the tongue, a program called Opti-Speech, can be used to improve speech.
- Conditions
- Articulation Disorder, Dysarthria, Prelingual Deafness
- Trial name
- NCT02705326
- Testing
- Opti-Speech
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Vulintus, Inc.
Suicide, Attempted, Cognitive Symptoms
Study of Cognitive Inhibition Disorders in Depressed Older Suicide Attempters
The purpose of this study is to compare the cognitive inhibition deficit among depressed older suicide attempters compared to depressed older suicide non-attempters.
- Trial name
- ETIC (NCT01333215)
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Strabismus, Bradycardia
Strabismus Recovery With Proparacaine and Oculocardiac Reflex
Observational study to determine if topical anesthetic and intraoperative oculocardiac reflex influence post strabismus surgery recovery.
- Conditions
- Strabismus, Bradycardia, Nausea, Pain
- Trial name
- OCRprop (NCT03672435)
- Testing
- Topical Solution
- Volunteers
- 140 people
- Sponsor
- Alaska Blind Child Discovery
Fatigue, Sleep Deprivation
Effect and Utilization of Protected Time Among Interns on Extended Duty-Hour Call Shifts
This study will test the feasibility and effectiveness of protected time for physicians in training during 30 hour shifts in a medical intensive care unit. The primary outcome will be fatigue.
- Conditions
- Fatigue, Sleep Deprivation, Depression
- Trial name
- NCT00983008
- Testing
- Protected time and Dedicated time
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Providence Health & Services
Fibromyalgia
Remote Gamified Sensory Perceptual Training for Patients With Fibromyalgia: a Feasibility Trial
The purpose of this study is to determine the feasibility of gamified sensory perceptual training in people with fibromyalgia. The primary aim is to determine the feasibility of at-home somatosensorial training for people with…
- Trial name
- NCT04919525
- Testing
- TrainPain
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Muscle Spasticity, Stroke
OnabotulinumtoxinA Treatment in Adult Patients With Upper Limb Spasticity
This is a safety and efficacy study of onabotulinumtoxinA in poststroke patients with upper limb spasticity.
- Trial name
- NCT02145676
- Testing
- onabotulinumtoxinA
- Where
- 2 sites in United States, Canada
- Volunteers
- 53 people
- Sponsor
- Allergan
Plexus Choroideus, Metabolic Syndrome
Choroid Plexus Dysfunction in Neurological Diseases
Cerebral folate deficiency (CFD), a partially treatable condition defined by a low folate cerebrospinal fluid (CSF) concentration, can be linked to genetic defects of folate metabolism or be secondary to various diseases without…
- Trial name
- PLEXFOLD (NCT06403189)
- Testing
- Biologic samples and MRI
- Where
- 2 sites in France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Wet Age-related Macular Degeneration
A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared With Intravitreal Aflibercept in Participants With Neovascular (Wet) Age-related Macular Degeneration (wAMD)
This Phase 3 study will evaluate the efficacy and safety of KSI-301 compared to aflibercept, in participants with neovascular (wet) age-related macular degeneration (wAMD)
- Trial name
- DAYLIGHT (NCT04964089)
- Testing
- KSI-301, Aflibercept
- Where
- 66 sites in United States, Puerto Rico
- Volunteers
- 557 people
- Sponsor
- Kodiak Sciences Inc
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