Clinical trials: Neurological Diseases
Enhanced Recovery After Surgery, Anesthesia
Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery
Early mobilization is an important factor in increasing postoperative colorectal surgeries outcome. There are four components held by anesthesiologist in Enhanced Recovery After Surgery protocol for colorectal surgery in our…
- Conditions
- Enhanced Recovery After Surgery, Anesthesia, Surgery-Complications, Colorectal
- Trial name
- NCT06065696
- Testing
- Early mobilization, No early mobilization
- Where
- Indonesia
- Volunteers
- 343 people
- Sponsor
- Universitas Indonesia
Neuropathic Pain
Placebo-controlled Safety and Efficacy Study of Pregabalin in Subjects With Post-traumatic Peripheral Neuropathic Pain
This study is designed to investigate if pregabalin is effective in treating neuropathic (nerve) pain resulting from peripheral nerve trauma due to a traumatic or surgical event such as, for example, motor vehicle accident, fall…
- Trial name
- NCT01701362
- Testing
- pregabalin
- Where
- 156 sites in United States, Bulgaria and 11 more
- Volunteers
- 542 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Pain, Neuropathic, Neuropathic Pain
Effect of GSK1014802 on Electrical Hyperalgesia and Threshold Tracking in Healthy Subjects
This study is being conducted to assess the effects of GSK1014802 and a positive control, lidocaine, on tests of peripheral nerve excitability. This will be a double blind, placebo controlled, 4-period cross over study.
- Trial name
- NCT00964288
- Testing
- GSK1014802 low dose, Lidocaine, GSK1014802 high dose
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Biogen
Delirium
Clinical Evaluation Program of DeltaScan (Ward)
Rationale: Delirium, or acute brain failure, presents as an acute confusional state, and is associated with prolonged hospitalization, an increased risk of dementia, institutionalization and mortality, as well as increased costs.
- Trial name
- NCT03735927
- Where
- Netherlands
- Volunteers
- 3,907 people
- Sponsor
- UMC Utrecht
Stuttering, Adult
Information Processing Biases in Adults Who Stutter
The goal of this clinical trial is to examine whether stuttering is associated with a tendency to attend more quickly or for longer durations to threat-related information in the environment (threat-related attention bias).
- Trial name
- NCT06422442
- Testing
- Threat-related stimulus exposure
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Low Back Pain
Determining the Effectiveness of the Pain and Disability Drivers Management Model on the Management of Low Back Pain
This study aims to assess the feasibility of procedures for conducting a pragmatic cluster nonrandomized controlled trial and to collect data on the effectiveness of a previously validated approach that takes into account all the…
- Trial name
- NCT04893369
- Testing
- The Low Back Pain and Disability Drivers Management model, Low back pain clinical practice guidelines
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Université de Sherbrooke
Primary Progressive Aphasia
The Effects of a Multimodal Approach for the Treatment of PPA
Primary Progressive Aphasia (PPA) is an untreatable neurodegenerative disorder that disrupts language functions. Available therapies are mainly symptomatic and recently attention has been gained by new techniques that allow for…
- Trial name
- ACROSS (NCT04187391)
- Testing
- Active tDCS, Language training, Unstructured cognitive training
- Where
- Italy
- Volunteers
- 47 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Abetalipoproteinemia
Vitamin Replacement in Abetalipoproteinemia
This study will determine whether short term intravenous infusion of vitamins A and E in patients with abetalipoproteinemia can reverse disease symptoms in these patients.
- Trial name
- NCT00004574
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Dystonia
Clinical Trial of STN-DBS for Primary Cranial-Cervical Dystonia
Primary cranial-cervical dystonia is managed mainly by repeated botulinum toxin injections.This study is to establish whether subthalamic nucleus neurostimulation could improve symptoms in patients not adequately responding to…
- Trial name
- STN-CCD (NCT02583074)
- Testing
- Stimulation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Beijing Tiantan Hospital
Tinnitus
DMSO Dual-Route Therapy for Refractory Tinnitus in Long-COVID and Post-COVID-19 Vaccine Injury
The goal of this clinical trial is to test a compounded dimethyl sulfoxide (DMSO)-based dual-route therapy for adults with refractory subjective tinnitus linked to long-COVID (post-acute sequelae of SARS-CoV-2) or post-COVID-19…
- Trial name
- DART-TINN (NCT07567274)
- Testing
- DMSO-based otic solution with betahistine, dexamethasone, and lidocaine, DMSO-based transdermal cream with levocarnitine and N-acetylcysteine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Leading Edge Clinic
Opioid-Related Disorders, Chronic Pain
Study of the Treatment of Experimental Pain in Buprenorphine Maintained Persons With Chronic Musculoskeletal Pain
Pain is very common in persons with a history of addiction, but few studies have examined the best treatment of pain in this population.
- Trial name
- 1401 (NCT02372591)
- Testing
- Buprenorphine, Hydromorphone
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Johns Hopkins University
Intensive Care Unit (ICU) Acquired Weakness (ICU - AW), Muscle Weakness
Nutrient Pattern Analysis in Critically Ill Patients (NAChO)
Little is known about nutritional Parameters that potentially influence the course of intensive-care unit acquired weakness (ICU - AW).
- Trial name
- NAChO (NCT02839018)
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain Management, Satisfaction
Effectiveness of Game-Based Learning in Pain Management Education for Nursing Students
Aim: To evaluate the effectiveness of game-based learning on undergraduate nursing students' pain management knowledge, learning motivation, and educational satisfaction. Background: Pain management is a core nursing competency.
- Conditions
- Pain Management, Satisfaction, Motivation, Knowledge
- Trial name
- NCT07736118
- Testing
- game-based learning
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- TC Erciyes University
Traumatic Brain Injury
Sodium Lactate in Severe TBI
This is a safety phase 2 clinical trial of intravenous infusion of sodium lactate in patients with severe TBI. This study is intended for patients in the acute setting in an intensive care unit at centers that have been selected…
- Trial name
- NCT06701760
- Testing
- Sodium Lactate
- Volunteers
- 264 people
- Sponsor
- University of California, Los Angeles
Cancer, Oropharynx, Pain, Intractable
Ropivacaine/Dexamethasone and 10% Lignocaine Injection in GPN Block for Intractable Cancer Pain
The study will compare the efficacy and safety of Ropivacaine/dexamethasone vs 10% lignocaine injection in distal glossopharyngeal nerve block for intractable cancer pain
- Conditions
- Cancer, Oropharynx, Pain, Intractable, Cancer Pain
- Trial name
- NCT04085120
- Testing
- 0.75 % Ropivacaine/ 4mg/mL dexamethasone injection, 10% lignocaine injection
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences
Analgesia
Effect of the Quadratus Lumborum Block Versus the Lumbar Plexus for Spiral Thighplasty Surgery
Whether trans muscular QLB provides postoperative analgesia compared with LPB after thigh lift surgery
- Trial name
- QLB&LPB (NCT07280182)
- Testing
- Ultrasound-Guided Trans-muscular QLB, Ultrasound-Guided Posterior Lumbar Plexus (Psoas Compartment) Block
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Menoufia University
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Sweden Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01667003
- Where
- 8 sites in Sweden
- Volunteers
- 406 people
- Sponsor
- Biotronik ApS
Sleep Disturbance
Reports on Sleep Quality and Thermoregulation Among Veterans
To assess and compare the quality of sleep self- reported by veterans with sleep disorders before and after use of the Chilipad cooling mattress pad
- Trial name
- ReSQuTheVets (NCT04236661)
- Testing
- chilipad
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Post-Surgical Pain, Chronic, Post-traumatic Pain, Chronic
Uncovering the Mechanism of Pain Relief by Peripheral Transcutaneous Magnetic Stimulation
This research aims to uncover the Mechanisms of pain relief through the FDA-cleared peripheral transcutaneous magnetic stimulation (pTMS) device by MagVenture.
- Trial name
- NCT07199361
- Testing
- Peripheral Transcutaneous Magnetic Stimulation from MagVenture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Florida International University
Dyslexia
Study of Hierarchy of Afferents in Postural Control of Children With Dyslexia
The purpose is to determine the hierarchy of sensory afferents according to different forms of dyslexia in children. The secondary purpose is to determine sensitive and sufficiently specific posturographic indexes for standard…
- Trial name
- EQUIDYS (NCT02879786)
- Testing
- Posturographic tests, Questionnaire of motion sickness susceptibility
- Where
- France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
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