Clinical trials: Neurological Health
Critical Illness, Communication Disabilities
Enhancing & Mobilizing the POtential for Wellness & Emotional Resilience Among Surrogate Decision-Makers of ICU Patients
Intensive Care Units (ICU) are stressful places where life-and-death medical decisions are made and patients' surrogate decision-makers are exposed to potentially traumatic experiences.
- Trial name
- EMPOWER (NCT03276559)
- Testing
- EMPOWER, Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Postoperative Pain, Cesarean Section Complications
Effect of Quadratus Lumborum Block in C/S
to compare postoperative analgesic effects of USG guided QLB-2 and QLB-3 blocks after C/S. We hypothesized that QLB-3 may be more effective for pain relieving than QLB-2 after C/S.
- Conditions
- Postoperative Pain, Cesarean Section Complications, Block, Patient Satisfaction
- Trial name
- NCT04733313
- Testing
- ultrasound guıded quadratus lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Irreversible Pulpitis
Post Operative Pain and Oral Health Related Quality of Life Following Pulpotomy VS Extraction of Permanent First Molar
The goal of this clinical trial is to compare between post operative pain and oral health related quality of life in participants receiving two treatments for first permanent mandibular molars with poor prognosis.
- Trial name
- NCT06420583
- Testing
- MTA pulpotomy, Extraction
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Pain
Chronic Pain Care Network
The proposed Nova Scotia Chronic Pain Collaborative Care Network (NSCPCCN) is a professional development partnership between family physicians and chronic pain and addiction specialists designed to build capacity in the health…
- Trial name
- NSCPCCN (NCT00909493)
- Testing
- Network Access
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Pain
Study of Pain Control With Hormonal IUS Insertion
This study aims to compare pain during insertion of the Skyla® IUS using a 100mm visual analog scale (VAS) among 92 young women aged 14 to 22 years randomized to receive a paracervical (n=46) block versus a sham paracervical…
- Trial name
- SOPHI (NCT02352714)
- Testing
- Paracervical Nerve Block
- Where
- 3 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Chronic Pain
Development/Testing of SUMMIT: a Tool to Help Patients Manage Pain While Tapering Opioids
There are nearly one million veterans being treated with long-term opioid therapy (LTOT) for chronic pain. Numerous short and long-term harms associated with LTOT and mounting evidence suggest they have modest or no benefit.
- Trial name
- NCT04746833
- Testing
- SUMMIT, control
- Where
- 4 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Delirium, Fall Injury
Care.Coach Avatars for Improvement of Outcomes in Hospitalized Elders, Including Mitigation of Falls and Delirium: a Multi-Site Clinical Study
Through NINR project 1R44NR017842-01 which preceded the present study, the investigators enhanced the care.coach avatar platform to incorporate a robust suite of evidence-based protocols based on the Hospital Elder Life Program…
- Trial name
- AvatarHELP (NCT03832192)
- Testing
- care.coach Avatar (HELP-Protocolized)
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Victor Wang
Neurological Disorders, Health Adult Subjects
A Muscle-brain Interplay Study in Neurological Disorders
Despite the improvements in life expectancy, neurodegenerative diseases (NDGs) have become the most dreaded disorders of older people.
- Trial name
- M-Brain (NCT07477821)
- Where
- 4 sites in Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Visual Impairment
mHealth Intervention for Improving Eye Health at Community Level
This study is a community trial that aims to establish and evaluate an mHealth screening and promotional tool for improving eye health in Iran.
- Trial name
- Vison mHealth (NCT03922347)
- Testing
- Screening program including 2 consecutive tests, Screening program with mobile health
- Where
- Iran
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Muscle Loss
Galactooligosaccharide and Aging
Sarcopenia is a progressive muscle disease, most commonly affecting older individuals, that is categorised by 1) low muscle strength, 2) low muscle quantity or quality, and 3) low physical performance.
- Trial name
- NCT06411964
- Testing
- Prebiotic
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bath
Environmental Exposure, Winter Depression
Health Consequences of Wintering in the French Southern and Antarctic Territories
Polar stays expose people to extreme climate, isolation and confinement. The combination of these factors induces psychological disorders, sleep disorders, immune and endocrine disturbances, and deficiencies.
- Conditions
- Environmental Exposure, Winter Depression, Endocrine System Diseases, Sleep Disorder
- Trial name
- MediTAAF (NCT04768621)
- Testing
- Questionary
- Where
- Reunion
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Body Composition, Beneficial, Paresis
Meal Patterning on Weight Loss With Changes to Body Comp, Muscle and Metabolic Health
About two-thirds of adults in the United States are overweight or obese with likely adverse health consequences. A Moderate weight loss by dieting and exercise is recommended to improve health.
- Conditions
- Body Composition, Beneficial, Paresis, Impaired Glucose Tolerance
- Trial name
- S38 (NCT02066948)
- Testing
- wt loss, Meal Pattern, even
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Purdue University
Down Syndrome
An Online Health Tool About Down Syndrome: Down Syndrome Clinic to You
The investigators conducted a national two-arm, randomized controlled trial of caregivers of individuals with DS to assess the efficacy of DSC2U in assuring adherence to evidence-based guidelines.
- Trial name
- DSC2U (NCT04227197)
- Testing
- Down Syndrome Clinic to You (DSC2U)
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
The Impact of Extreme Physical Exertion on Health, The Impact of Extreme Physical Exertion on Glucose
A Comprehensive Interdisciplinary Assessment of the Impact of Ultramarathons on the Health of Middle-aged and Older Amateur Runners - SUPERMARATON 2025 Project
The "Supermarathon 2025" study was designed as a prospective, interdisciplinary field study to assess the impact of extreme physical exertion, such as a 100-kilometer ultramarathon, on the health of individuals aged ≥ 45 years.
- Conditions
- The Impact of Extreme Physical Exertion on Health, The Impact of Extreme Physical Exertion on Glucose, The Impact of Extreme Physical Exertion on Respiratory System, The Impact of Extreme Physical Exertion on Joints and Muscles
- Trial name
- NCT07451717
- Testing
- Blood and urine analysis
- Where
- Poland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Abdominal Pain, GI Disorders
Radicle GI Health 24: A Study of Health and Wellness Products on GI Health and Related Health Outcomes
A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on GI health and related health outcomes
- Conditions
- Abdominal Pain, GI Disorders, Digestion
- Trial name
- NCT06376695
- Testing
- Radicle GI Health Active Study Product 1.1 Usage, Radicle GI Health Active Study Product 2.1 Usage
- Where
- United States
- Volunteers
- 4,607 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Stress Disorders, Stress
Measuring the Effectiveness of Forest Therapy to Alleviate Stress Among International Students
International students often face high levels of stress, leading to mental health conditions, from factors including cultural and social change, educational system, financial insecurity and family responsibilities.
- Conditions
- Stress Disorders, Stress, Anxiety, Anxiety Depression (Mild or Not Persistent)
- Trial name
- FTIS-2024 (NCT06792656)
- Testing
- standardized Forest Therapy session (120 min)
- Where
- Australia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- International Nature and Forest Therapy Alliance
Alteration of Cognitive Function, Ageing
Health Behaviors and Time-of-Day: Older Adult Cognitive Function
This is a single-center, observational study design. Enrolled participants will be typically, healthy older adults. Participants will complete daily computerized measures, in addition to continuously wearing an Actiwatch device.
- Trial name
- OA-TIME (NCT02300272)
- Testing
- Polysomnograph, Actiwatch
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Florida
Laughter Yoga
The Effect of Laughter Yoga on Pain, Fatigue, and General Well-Being in Cancer Patients and Their Caregivers
This study aims to evaluate the effect of laughter yoga on pain, fatigue, and general well-being in cancer patients and their caregivers.
- Trial name
- NCT06995248
- Testing
- Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment, Mild Dementia
Assessing Cognitive Decline at Home
Neuropsychiatric symptoms (NPS) refer to a range of mental and emotional issues that can be observed through how patients move, perform daily tasks, and express feelings on their faces.
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Dementia Alzheimers, Dementia
- Trial name
- NCT06704971
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Stanford University