Clinical trials: Neuromuscular Block, Recovery
Neuromuscular Residual Curarization
Comparison of the TOFScan and the WiTOF During Recovery of Neuromuscular Function
The purpose of this study is to compare two neuromuscular blockade monitors on recovery from an ATRACURIUM intra veinous injection for surgery. The TOFscan, a wired connected monitors and the WiTOF, a wireless connected monitor.
- Trial name
- NCT05231525
- Testing
- WiTOF, TOFscan
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Anesthesia Recovery
"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"
Prospective Randomized non inferiority Trial involving adult patients undergoing elective surgery under general anesthesia.56 Patients will be enrolled in 2 groups : full dose sugammadex vs half dose sugammadex for reversal of…
- Trial name
- NCT02375217
- Testing
- Sugammadex, Neostigmine, glycopyrrolate
- Where
- Lebanon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Neuromuscular Blockade, Neuromuscular Monitoring
A Comparison Between TOF Watch® SX and Tetragraph®
This observational study was designed to assess the agreement between the recently marketed electromyographic neuromuscular blockade monitor Tetragraph® (Senzime, Uppsala, Sweden) and the TOF Watch® SX (Organon Teknika B.V.…
- Trial name
- NCT04947306
- Testing
- Tetragraph® (Senzime, Uppsala, Sweden), TOF Watch® SX (Organon Teknika B.V., Boxtel, Holland)
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Muscle Relaxant, General Anesthesia
Effect of Neostigmine on the Recovery of Rocuronium: A Comparison Between Partial and TOF Ratio-Based Dose
This study aimed to evaluate the effect of Neostigmine partial dose towards neuromuscular blockade of rocuronium
- Trial name
- NCT03058263
- Testing
- Dose of Neostigmine
- Where
- Indonesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Neuromuscular Blockade
Comparison of the TOFscan and the TetraGraph During Recovery of Neuromuscular Function
Assess the values of train-of-four ratios with the TetraGraph and thoses obtained with the TOFscan during recovery of neuromusculat function in surgical patients who have been administred rocuronium.
- Trial name
- DECURAR-EMG (NCT04816539)
- Testing
- TetraGraph
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Muscle Relaxation
Deep vs Moderate Neuromuscular Blockade in Day Case Laparoscopic Cholecystectomy.
Laparoscopic cholecystectomy (LC) is commonly performed on ambulatory basis as a result of its ability to improve postoperative quality of recovery (QOR) and significantly reduce hospital stay .
- Trial name
- NCT03881423
- Testing
- Rocuronium Bromide
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wahba bakhet
Peripheral Chemosensitivity
The Breath-2 Trial
This is a randomized, cross over, experimental trial in which carotid body function will be evaluated in 35 healthy subjects during partial muscle relaxation and after recovery from muscle relaxation
- Trial name
- NCT05149872
- Testing
- Muscle relaxation, Reversal
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Postoperative Residual Neuromuscular Blockade
Electromyographic Monitoring and Postoperative Recovery
Residual neuromuscular blockade (weakness) is a common occurrence in the postanesthesia care unit when muscle relaxant drugs have been used in the operating room.
- Trial name
- NCT03891381
- Testing
- Tetragraph quantitative monitoring
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Muscle Relaxation
Deep NMB in Ambulatory Gynecological Laparoscopy
Gynecological laparoscopic surgery is commonly performed as an ambulatory basis for the aim of rapid discharge, reduce hospital stay with reduced costs and to improve postoperative QOR [1,2].
- Trial name
- NCT04105764
- Testing
- Rocuronium, Rocuronium bromide
- Where
- Kuwait
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Wahba bakhet
Respiratory Muscles, Electromyography
Electromyographic Activity of the Respiratory Muscles During Neostigmine or Sugammadex Enhanced Recovery After Neuromuscular Blockade
It was recently shown that neostigmine reversal was associated with increased atelectasis and that high-dose neostigmine was associated with longer postoperative length of stay and with an increased incidence of pulmonary edema…
- Trial name
- REDNESII (NCT02403063)
- Testing
- Sugammadex, Neostigmine, Neostigmine-sugammadex
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Onze Lieve Vrouw Hospital
Rocuronium, Muscle Weakness
General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery
Neuromuscular blocking agents are often used during general anesthesia. Also, general anesthesia may be performed without use of neuromuscular blocking agents.
- Conditions
- Rocuronium, Muscle Weakness, General Anaesthesia
- Trial name
- NCT04760912
- Testing
- Rocuronium, General anesthesia for surgery
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Neuromuscular Block Prolonged
Hand Dynamometer and Clinical Tests to Evaluate Neuromuscular Recovery in Atracurium vs Rocuronium
One of the common serious complications in the postoperative phase is Residual the neuromuscular blockade that confused the anesthesia medical team also patients may become uncomfortable, un ability to clear secretion…
- Trial name
- NCT05657756
- Testing
- Randomize clinical trial using hand dynamometer
- Where
- Iraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al Safwa University College
Residual Neuromuscular Block
Neostigmine Reversal And Neuromuscular Recovery
Patients undergoing surgery often receive paralytic agents (or neuromuscular blocking agents (NMBAs)) to facilitate the procedure. At the end of surgery, the effects NMBAs are reversed with a drug called neostigmine.
- Trial name
- NCT02433808
- Testing
- Neostigmine Group, No Neostigmine group
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Neuromuscular Blockade
Comparison of Neuromuscular Recovery at the Hand and Foot
Gold standard for neuromuscular blockade evaluation is accelerometry in three dimensions at the thumb. There are many times that measurement at the hand can be falsely under-estimated intraoperatively secondary to constriction of…
- Trial name
- NCT06236763
- Testing
- TOFscan foot
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal