Clinical trials: Neuromuscular Blockade
Muscular Dystrophy, Duchenne
Safety Study of BLS-M22 in Healthy Volunteers
BLS-M22 is being developed as an anti-myostatin agent for the treatment of Duchenne Muscular Dystrophy (Muscular Dystrophy). A total of 37 subjects participated in this study to confirm the safety of BLS-M22.
- Trial name
- NCT03789734
- Testing
- BLS-M22
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- BioLeaders Corporation
Stress, Stress, Physiological
The Effect of Progressive Relaxation and Breathing Exercises Accompanied by Music on the Stress Levels of Nursing Students and Their Bio-psycho-social Responses
This clinical study will be conducted to determine the effects of musically accompanied progressive muscle relaxation and deep breathing exercises on nursing students' stress levels and bio-psycho-social responses to stress.
- Trial name
- NCT06008236
- Testing
- Progressive Muscle Relaxation and Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
MELAS Syndrome, Mitochondrial Respiratory Chain Deficiencies
Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male Volunteers
The purpose of this First In Human study is to investigate the safety and tolerability of KL1333 after a single oral dose and to investigate the pharmacokinetic characteristics of KL1333 after a single oral dose.
- Trial name
- NCT03056209
- Testing
- KL1333 25 mg, KL1333 50 mg, KL1333 100 mg
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yungjin Pharm. Co., Ltd.
Microlaryngoscopy, Rigid Bronchoscopy
Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy
Use of Muscle relaxant and reversal with Sugammadex at end of airway procedures will reduce the time to extubation after end of procedure
- Trial name
- NCT03111121
- Testing
- Sugammadex, neostigmine, glycopyrrolate
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Gastrointestinal Cancer, Sarcopenia
Sarcopenia and Neuromuscular Block in Gastrointestinal Cancer Surgery
This prospective observational study aims to evaluate the effects of sarcopenia on intraoperative neuromuscular block (NMB) in patients undergoing gastrointestinal cancer surgery.
- Conditions
- Gastrointestinal Cancer, Sarcopenia, Neuromuscular Blockade
- Trial name
- NCT07003061
- Testing
- Standard Anesthesia Management
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Stress
Progressive Muscle Relaxation (PMR) in Stress Management Among Physiotherapy Students
The objective of this clinical trial is to observe the effect of Virtual Reality (VR) and Progressive muscle relaxation (PMR) in stressed individuals.
- Trial name
- NCT06028360
- Testing
- Progressive Muscle Relaxation, Virtual Reality Therapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shalamar Institute of Health Sciences
Cholecystitis, Inguinal Hernia, Direct
No Need for Neuromuscular Blockade in Daycase Laparoscopic Surgery
This study analyse the need for neuromuscular blockade in consecutive routine laparoscopic procedures without standard use of neuromuscular blockade in an ambulatory laparoscopic surgery setting and analyse specific reasons for…
- Conditions
- Cholecystitis, Inguinal Hernia, Direct, Umbilical Hernia
- Trial name
- NCT02782832
- Volunteers
- 1,245 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Muscle Relaxation
Effectiveness of Sugammadex in LMS Surgery
This study is comparing of rocuronium-sugammadex and succinylcholine during LMS surgery that is characterized by short operation time, required intense paralysis and ambulatory setting, has not been investigated.
- Trial name
- NCT02329964
- Testing
- Sugammadex, Neostigmine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Meralgia Paresthetica
Comparing Ways to Freeze the Nerve That Provides Thigh Sensation
Background The sensation on the outside of portion of our thighs is provided by a nerve called the lateral femoral cutaneous nerve (LFCN).
- Trial name
- NCT02577510
- Testing
- Nerve Injection- Nerve Stimulator, Nerve Injection - Ultrasound
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Canadian Forces Health Services Centre Ottawa
Cesarean Section Complications
Effects of Deep Breathing Excer. With & Without PMR on Post C Section LBP, QOS & PA
To find out the Effects of deep breathing exercises with and without Progressive Muscle Relaxation Technique on Post Cesarean Section low back Pain, Quality of Sleep and Physical Activity
- Trial name
- NCT05463146
- Testing
- Deep breathing excercises, Deep breathing exercises +and progressive muscle relaxation techniques, Deep breathing exercises
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
NEUROLINGUISTIC PROGRAMMING, PROGRESSIVE MUSCLE RELAXATION EXERCISES
Neurolinguistic Programming, Progressive Muscle Relaxation Exercises, and Breastfeeding
The effect of neuro linguistic program and progressive muscle relaxation exercises on breastfeeding success and breastfeeding self-efficacy after caesarean section.
- Conditions
- NEUROLINGUISTIC PROGRAMMING, PROGRESSIVE MUSCLE RELAXATION EXERCISES, CAESAREAN SECTION
- Trial name
- NCT06070792
- Testing
- NEURO LINGUISTIC PROGRAM, PROGRESSIVE MUSCLE RELAXATION EXERCISES
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Aysegul Kilicli
Brain Tumors
Effect of Sugammadex for Reversal of Rocuronium-induced Neuromuscular Block on Perioperative Management of Awake Craniotomy
Effect of sugammadex for reversal of rocuronium-induced neuromuscular block on Perioperative Management of awake Craniotomy
- Trial name
- NCT05202899
- Testing
- sugammadex
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Parent, Anxiety
Effect of Progressive Muscle Relaxation on Parental Anxiety
This randomized controlled trial aims to evaluate the effect of progressive muscle relaxation exercises on anxiety levels among parents who are the primary caregivers of children diagnosed with cancer and receiving inpatient…
- Conditions
- Parent, Anxiety, Cancer, Progressive Muscle Relaxation
- Trial name
- PMR-PA (NCT07797608)
- Testing
- Progressive Muscle Relaxation
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Complex Regional Pain Syndromes
Feasibility Study of Combined Peripheral Nerve Block and Physiotherapy for CRPS
Chronic pain is a debilitating condition affecting 1 in 5 Canadians with a yearly economic cost of over $40 billion in healthcare spending and loss of productivity.
- Trial name
- NCT05589259
- Testing
- Axillary Brachial Plexus Block plus Physiotherapy, Physiotherapy alone
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tracy Cupido
Sleep Disturbance in Athletes
Effectiveness of Progressive Muscle Relaxation on Sleep Disturbance in Athletes
Literature supports that athletes have so many reasons for sleep disturbance in their day to day practice and during competition.
- Trial name
- NCT05695092
- Testing
- Progressive muscle relaxation, control
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Neuromuscular Blockade
The Effect of Sugammadex Versus Neostigmine During Neuromuscular Blockade Reversal
Patients who undergo surgery receive drugs called neuromuscular blocking agents (NMBA) that to block the activity of muscles. When the surgery is over, the block needs to be reversed.
- Trial name
- NCT03579589
- Testing
- Sugammadex vs Neostigmine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Carpal Tunnel Syndrome, Anesthesia, Local
Ultrasound-guided Peripheral Nerve Block Versus Forearm Bier's Block in Patients Undergoing Carpal Tunnel Release
By means of an observer-blinded, randomized controlled trial, the analgesic efficacy of the forearm intravenous regional anesthesia and the ultrasound guided peripheral nerve block will be investigated in patients undergoing…
- Trial name
- NCT03411551
- Testing
- regional anesthesia
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
Peripheral Nerve Injury
Needle Nerve Contact in Ultrasound Guided Femoral Block
Ultrasound-guided femoral nerve block is a common regional anesthesia technique. The optimal method of needle guidance (in-plane versus out-of-plane) with regards to the block efficacy and avoidance of needle-nerve contact has…
- Trial name
- NCT01554722
- Testing
- Needle placement
- Where
- 2 sites in United States, Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Older People
The Effect of Progressive Relaxation Exercise on Adaptation to Old Age and Quality of Life.
The changes and limitations that occur in the aging process effect people's adaptation toold age. The quality of life of elderly individuals who have problems in adaptation to aging is negatively affected.
- Trial name
- NCT04148196
- Testing
- Progressive muscle relaxation exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Aksaray University Training and Research Hospital
Postoperative Complications, Neuromuscular Blockade
The Effect of Sugammadex Versus Neostigmine on Postoperative Pulmonary Complications
Substantial respiratory morbidity has been associated with postoperative residual paralysis, which is fairly common after general anesthesia involving a neuromuscular blocking agent.
- Trial name
- NCT02861131
- Testing
- Sugammadex, Neostigmine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University