Clinical trials: Neuromuscular Blockade
Respiratory Insufficiency
Effect of Neuromuscular Blockade and Reversal on Breathing
In this study the investigators will assess (i) the effect of partial neuromuscular blockade (NMB; TOF ratio 0.8 and 0.6) induced by low-dose rocuronium on the ventilatory response to isocapnic hypoxia and (ii) the effect over…
- Trial name
- BREATH (NCT02845375)
- Testing
- Sugammadex, Neostigmine
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Neuromuscular Blockade, Anesthesia
Evaluation of Intubation Conditions Following BX1000 or Rocuronium in Subjects Undergoing Surgery
Assessment of Intubation conditions following administration of neuromuscular blocking agents; BX1000 (investigational) or rocuronium (active control).
- Conditions
- Neuromuscular Blockade, Anesthesia, Surgery
- Trial name
- NCT05687253
- Testing
- BX1000, Rocuronium Bromide
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baudax Bio
Benson Exercise, Mandala Coloring
The Effect of Benson Relaxation Exercise and Mandala Coloring Activity on Stress, Anxiety, and Mental Health of Palliative Caregivers (Benson Relaxation Technique (BRT), Mandala Coloring Activity (MCA))
This study aimed to examine the effects of mandala coloring activities, applied in conjunction with Benson relaxation exercises, on the stress, anxiety, and mental well-being of caregivers in a palliative care clinic.
- Conditions
- Benson Exercise, Mandala Coloring, Informal Palliative Caregiver
- Trial name
- BRT MCA (NCT07450924)
- Testing
- mandala coloring activity, Benson relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Anesthesia Recovery
"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"
Prospective Randomized non inferiority Trial involving adult patients undergoing elective surgery under general anesthesia.56 Patients will be enrolled in 2 groups : full dose sugammadex vs half dose sugammadex for reversal of…
- Trial name
- NCT02375217
- Testing
- Sugammadex, Neostigmine, glycopyrrolate
- Where
- Lebanon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Neuromuscular Block, Residual
Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in Children
This study is to evaluate the recovery of diaphragm function and atelectasis after reversal of neuromuscular blockade with Neostigmine and Sugammadex using lung ultrasound and diaphragm ultrasound for children aged 2 to 7 who are…
- Trial name
- NCT05724550
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Knee Osteoarthritis
Effects of Genicular Nerve Block in Knee Osteoarthritis
Genicular nerve block is a safe and effective therapeutic procedure for intractable pain associated with chronic knee osteoarthritis (OA). There is increasing support for the neuropathic component to the knee OA pain.
- Trial name
- NCT03781843
- Testing
- Genicular nerve block with lidocaine, Genicular nerve block with saline, Genicular nerve block with dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Rocuronium, Muscle Weakness
General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery
Neuromuscular blocking agents are often used during general anesthesia. Also, general anesthesia may be performed without use of neuromuscular blocking agents.
- Conditions
- Rocuronium, Muscle Weakness, General Anaesthesia
- Trial name
- NCT04760912
- Testing
- Rocuronium, General anesthesia for surgery
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Vasomotor Symptoms, Hot Flashes
The Effect of Health Education and Progressive Muscle Relaxation Exercise on Vasomotor Symptoms and Sleep Problems With Perimenopausal Women
This study aims to determine the effect of health education and progressive muscle relaxation exercise (PMRE) on vasomotor symptoms and sleep problems in women with perimenopausal period; a randomized, pretest-posttest is a…
- Conditions
- Vasomotor Symptoms, Hot Flashes, Sleep Problem
- Trial name
- NCT04808232
- Testing
- progressive muscle relaxation exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sidika Pelit Aksu
Chronic Otitis Media, Anesthesia
Optimal Dose of Combination of Rocuronium and Cisatracurium
BACKGROUND: The combinations of rocuronium and cisatracurium have a synergic effect. The investigators studied whether the prediction is possible to have a sufficient effect of reducing the dose when combining the two…
- Trial name
- CRC (NCT02495038)
- Testing
- 10% reduction of combination of Esmeron® and Nimbex®, 20% reduction of combination of Esmeron® and Nimbex®
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Polyneuropathies
Diagnostic Feasibility of 100 Hz Tetanic Stimulation
The goal of this observational study is to investigate the applicability of 100 Hz tetanic stimulation with an electromyography device in the exclusion of postoperative residual neuromuscular block.
- Trial name
- NCT06754995
- Where
- 2 sites in Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Debrecen
Progressive Muscle Relaxation, Deep Breath
Progressive Muscle Relaxation and Deep Breathing Exercises
The population of the study was composed of 186 patients whose cells were assigned to Atatürk University Hospital Educational Diseases Polyclinic between April and June 2023, and whose cells were found to have COPD according to…
- Conditions
- Progressive Muscle Relaxation, Deep Breath, COPD
- Trial name
- NCT05846204
- Testing
- Progressive Muscle Relaxation, Deep Breathing Exercise Group-DBE
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Relaxation
Measurement of Muscle Relaxation of the Hand in From Two Muscles and Two Hand Positions
Does movement of hand from supination to pronation affect the cut threshold for electomyography (EMG) relaxation measurement Does the threshold level differ between adductor pollucis and dorsal interosseus muscle
- Trial name
- NCT06711796
- Testing
- emg measurement in adductor pollucis
- Where
- Finland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Progressive Muscle Relaxation
Acute Effects of Progressive Muscle Relaxation on Brain Waves
In modern environments, stress is present regardless of age or social role. Stress does not always have negative effects; in fact, it is a necessary response for survival, known as the stress response.
- Trial name
- NCT07089537
- Testing
- progressive muscle relaxaiton, Rest
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Leukemia, Children
Jacobson's Progressive Muscle Relaxation Technique on Children With Leukemia Undergoing Chemotherapy.
The goal of this clinical trial is to determine the effect of Jacobson's progressive muscle relaxation technique on anxiety and fatigue among children with leukemia undergoing chemotherapy.
- Conditions
- Leukemia, Children, Fatigue Related to Cancer Treatment, Anxiety
- Trial name
- JPMRT (NCT06631196)
- Testing
- Jacobson's PMRT
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Pregnancy, Preeclampsia
Effects of Progressive Muscle Relaxation Exercise and Finger Grip Exercise on Stress, Anxiety, Fatigue, Sleep Quality, and Physiological Parameters in Pregnant Women With Preeclampsia
The aim of this study is to examine the effects of progressive muscle relaxation exercise and finger grip exercise on stress, anxiety, sleep quality, fatigue and physiological parameters in preeclamptic pregnant women.
- Trial name
- NCT07630623
- Testing
- Progressive Muscle Relaxation Exercise, Finger Grip Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Hatice Nur Nefes Pala
Spine Fracture
Comparison Of Deep Versus Moderate Neuromuscular Blockade on Intra-Operative Blood Loss During Spinal Surgery
Reduction of intra-operative blood loss
- Trial name
- NCT05294926
- Testing
- Rocuronium, nerve stimulator
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain Syndrome, Anxiety
Comparative Effects of Aerobic Exercises and Progressive Muscle Relaxation Exercises on Pain and Quality of Life
Premenstrual syndrome is the clinical condition in which reproductive age females suffer from emotional and physical symptoms not related to any disease, starting usually 5 days before the menstrual cycle for 3 consecutive cycles.
- Trial name
- NCT05811455
- Testing
- Aerobic exercises, Progressive muscle relaxation
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Premenstrual Disorder
The Effect of Progressive Muscle Relaxation Exercises on Premenstrual Syndrome, Anxiety, and Tendency to Violence in Young Women
This study results will provide evidence on the effectiveness of Progressive Muscle Relaxation Exercises (PMRE) as a complementary method in improving Premenstrual Syndrome (PMS), an important women's health issue.
- Trial name
- NCT06909955
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Neuromuscular Block, Residual
Evaluation of Residual Neuromuscular Blockade and of Late Recurarization in the Post Anesthesia Care Unit in Patients Undergoing Videolaparoscopic Cholecystectomy
Neuromuscular blockade is essential to provide optimal conditions for tracheal intubation and also to facilitate the performance of surgeries involving mainly the abdominal cavity.
- Trial name
- NCT03831815
- Testing
- Cisatracurium
- Where
- Brazil
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Strabismus
Effect of Neuromuscular Blockade on the Oculomotor by Not Squinting Child
Strabismus is a common condition (4-6% of the population) . The screening and treatment is a public health issue. Indeed, beyond the disfigurement, this disease is very supplier of amblyopia which is definitive if it is not…
- Trial name
- STRABO (NCT02360969)
- Testing
- Examination of the eye
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne