Clinical trials: Neuromuscular Disorders
Non Sarcopenic Subjects, Possible Sarcopenia
Association Between Oral Hypofunction, Sarcopenia and Social Frailty in Community-dwelling Older Adults
Previous studies have provided a preliminary understanding of the likelihood of sarcopenia and the prevalence of sarcopenia in the elderly in the community.
- Conditions
- Non Sarcopenic Subjects, Possible Sarcopenia, Sarcopenia(With Low ASM by BIM)
- Trial name
- OSSF (NCT07658625)
- Testing
- Non interventional study
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Raynaud Disease, Raynaud Phenomenon
Investigation of the Rewarming og the Fingers After Cooling and the Autonomic Nervous System in Raynaud's Phenomenon
Patients with Raynaud's disease have an increased tendency of chest pain and migraine, and studies indicate that the disease might be associated with increased cardiovascular morbidity and mortality.
- Conditions
- Raynaud Disease, Raynaud Phenomenon, Hand and Arm Vibration Syndrome, Diabetes Mellitus
- Trial name
- RaynAUT (NCT03094910)
- Testing
- Examination of vibration perception threshold in fingertips, Ewing's tests, Tilt table test
- Where
- Denmark
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Amyotrophic Lateral Sclerosis, Neurodegenerative Diseases
Quantitative Measurement of Nutritional Substrate Utilization in Patients With Amyotrophic Lateral Sclerosis (ALS)
The work of Nau et. al (Nau KL, Bromberg MB, Forshew DA, Katcha Vl. Individuals with amyotrophic lateral sclerosis are in caloric balance despite losses in mass.
- Trial name
- NCT00714220
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Drexel University College of Medicine
Geriatrics, Neuromuscular Exercise
Comparison of Neuromuscular Exercises and Dance Therapy on Physical Performance and Kinesiophobia Results in Geriatrics
Objective: The aim of this study is to compare neuromuscular exercises and dance Therapy on physical performance and kinesiophobia results in geriatrics.
- Conditions
- Geriatrics, Neuromuscular Exercise, Dance Therapy, Kinesiophobia
- Trial name
- NE-DTinGR (NCT06395779)
- Testing
- Neuromuscular Exercise Group, Dance Therapy Group
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
Atrophy, Disuse, Insulin Resistance
Bedrest, Feeding Pattern, and Insulin Sensitivity
In the present study, the investigators will assess the impact of two different feeding patterns (continuous vs intermittent) on insulin sensitivity and muscle mass following bedrest.
- Trial name
- NCT02521025
- Testing
- Intermittent feeding pattern, Continuous feeding pattern
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Vitamin D Status, Osteoporosis
Vitamin D Status and Bone Health of Older Adults in Care Facilities
Vitamin D deficiency is proposed to be prevalent in community-dwelling older adults, with prevalence substantially higher among older adults in residential care facilities.
- Conditions
- Vitamin D Status, Osteoporosis, Sarcopenia
- Trial name
- NCT04399291
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Postherpetic Neuralgia, Healthy Age/Gender Matched Volunteers
Evaluation of Five Selected Markers in Skin Biopsies of Patients With Postherpetic Neuralgia and Healthy Controls
Postherpetic Neuralgia is a painful nerve condition that can occur when nerve fibers are damaged following an outbreak of shingles.
- Trial name
- STTR (NCT01379716)
- Testing
- skin biopsy
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Spinal Muscular Atrophy
A Registered Cohort Study on SMA
Spinal muscular atrophy (SMA) is an autosomal recessive disease that causes progressive muscle wasting and weakness due to loss of motor neurons in the spinal cord.
- Trial name
- NCT04010604
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Wan-Jin Chen
Axial Spondyloarthritis, Ankylosing Spondylitis
Osteosarcopenia in Axial Spondyloarthritis
Axial spondyloarthritis is a chronic inflammatory disease affecting the spine, sacroiliac joints, entheses, and sometimes peripheral joints with a close link to HLAB27.
- Conditions
- Axial Spondyloarthritis, Ankylosing Spondylitis, Axial Spondyloarthritis, Non-Radiographic, Osteoporosis
- Trial name
- NCT06577350
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Ankara University
Stroke
Real-time Neuromuscular Control of Exoskeletons
The purpose of this study is to develop a real-time controller for exoskeletons using neural information embedded in human musculature.
- Trial name
- NCT04661891
- Testing
- Isometric contractions, Isokinetic contractions, Dynamic contractions
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Low Back Pain
Study to Evaluate the Effectiveness of Orthopedic Spinal Supports in the Treatment of Low Back Pain
The purpose of this study is to determine whether orthopedic spinal supports are effective in the treatment of low back pain.
- Trial name
- NCT00553540
- Testing
- Back supports
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cleveland Clinic Florida
Sarcopenia, Osteoporosis
Ibuprofen Supplementation After Resistance Training and Its Effects on Bone in Older Women
Inflammation increases with aging and is implicated in the reduction of bone mass, muscle mass, and strength. Resistance training is safe and effective for increasing muscle mass and strength in older adults,however resistance…
- Trial name
- NCT01886196
- Testing
- Non-steroidal anti-inflammatory drug (Ibuprofen), Resistance exercise, Flexibility training
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Post Herpetic Neuralgia, Herpes Zoster
Treatment of Chronic Postherpetic Pain With Fat Grafting
This study evaluates the possible beneficial effect of fat grafting for post herpetic neuralgia.
- Trial name
- NCT03584061
- Testing
- Fat grafting
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Muscle Synthesis
Effects of Protein Blends on Muscle Protein Synthesis in Healthy Older Adults
During aging there is a tendency for muscle protein synthesis (growth) to become less efficient and the resulting consequence leads to reduced muscle mass (sarcopenia) which can affect strength and mobility.
- Trial name
- NCT01847261
- Testing
- Soy Dairy Protein Blend, Positive Control (Dairy Whey Protein)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DuPont Nutrition and Health
Poliomyelitis
3 Adjuvated Reduced Dose IPV-Al SSI and Non-adjuvated Full Dose IPV SSI Given as Primary Vaccinations to Infants
The background of the present clinical trial is the overall aim of the World Health Organization (WHO) to obtain eradication of polio in the world.
- Trial name
- NCT02347423
- Testing
- Primary series of immunisation comprised by 3 vaccinations IPV-Al SSI, IPV Vaccine SSI
- Where
- Dominican Republic
- Volunteers
- 824 people, healthy volunteers welcome
- Sponsor
- Statens Serum Institut
Detection Autoantibody of Myasthenia Gravis
The Specificity, Sensitivity and Clinical Correlation of CBA, RIPA and ELISA in Detecting AChR and MuSK IgG of Myasthenia Gravis
Myasthenia gravis (MG) is a neuromuscular junction (NMJ) disorder mediated by autoantibodies against AChR, MuSK or other autoantigens located at the post synaptic membrane of the neuromuscular junction.
- Trial name
- NCT05219097
- Testing
- CBA Assay
- Where
- 2 sites in China
- Volunteers
- 2,663 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University General Hospital
Myotonic Dystrophy 1, Muscular Dystrophies
Myotonic Dystrophy Type 1 Aerobic Exercise Study
Myotonic dystrophy type 1 (DM1) is a genetic disease that primarily targets skeletal muscle resulting in severe weakness and muscle loss.
- Trial name
- DM1ex (NCT04187482)
- Testing
- Exercise training
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- McMaster University
Sarcopenia, Chronic Lower Back Pain
Prevalence and Factors Associated With Sarcopenia in Pre-retirement Aged Adults With Chronic Non-specific Lower Back Pain
To study the prevalence of sarcopenia in a pre-retirement group with chronic lower back pain and factors associated between sarcopenia and chronic lower back pain in the pre-retirement group.
- Trial name
- NCT05894213
- Where
- Thailand
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Tetraplegia, Guillain-Barre Syndrome
Brain Computer Interface for Communication in ICU: a Feasibility Study
The main objective of this study is to evaluate the usability of a system to assist verbal communication based on BCI system using the P300 wave in patients with tetraplegia who can no longer communicate because of severe engine…
- Trial name
- RoBIK-1 (NCT01005524)
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Versailles
Amyotrophic Lateral Sclerosis, Motor Neuron Disease
Effects of Long Term Ventilation Support on the Quality of Life of ALS Patients and Their Families
Amyotrophic lateral sclerosis (ALS) is a serious rapidly progressive disease of the nervous system. The average survival from the time of diagnosis is two to three years.
- Conditions
- Amyotrophic Lateral Sclerosis, Motor Neuron Disease, Nervous System Diseases, Spinal Cord Diseases
- Trial name
- ALS-LTMV (NCT05744310)
- Testing
- Long term mechanical ventilation support, No long term mechanical ventilation support
- Where
- 9 sites in Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
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