Clinical trials: Neuromuscular Fatigue
Biological Maturation
Biological Maturation and Plyometric Exercise
Plyometric training comprises one of the most widely used training methods in both individual and team sports, and is widely used by coaches as one of the main training in both adults, and children.
- Trial name
- BiMaPlEx (NCT05442593)
- Testing
- Plyometric training
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Fatigue, Dyspnea
TaiChi-DTx for Treating Long Covid Symptoms
The randomized controlled trial will be conducted to evaluate the effectiveness of a Multi-domain Tai Chi Digital Therapy for treating the individuals suffering from the long term COVID-19 syndrome (Long COVID).
- Conditions
- Fatigue, Dyspnea, Cognitive Impairment, Muscle Pain
- Trial name
- TaiChi-DTx (NCT05419219)
- Testing
- the multi-domain Tai Chi Digital therapy Software Application
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tim Shi
Chronic Kidney Failure, Chronic Kidney Disease stage3
Pathophysiological Characterization of the Neuromuscular Function of a Population With Multiple Comorbidities Suffering From Chronic Renal Failure in Pre-dialysis.
The evolution of chronic kidney disease (CKD) causes a systemic upheaval on the body and a deep fatigue is very often described by patients (50-70% of the patients) even before the start of dialysis (pre-dialysis).
- Conditions
- Chronic Kidney Failure, Chronic Kidney Disease stage3, Chronic Kidney Disease, Stage 4 (Severe), Chronic Kidney Disease Stage 5
- Trial name
- PIONNIER (NCT03998917)
- Testing
- Discrimination of neuromuscular alterations protocol
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier le Mans
Chronic Fatigue Syndrome
Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With CFS
Use of Viagra to Alter Symptoms in Patients with Chronic Fatigue Syndrome (CFS)
- Trial name
- NCT00598585
- Testing
- Sildenafil (Viagra)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
A Trial of Solriamfetol in the Treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
This study is an 8-week single center, randomized, double-blind, placebo-controlled, flexible titration trial evaluating the efficacy of solriamfetol in the treatment of fatigue symptoms in adult patients with chronic fatigue…
- Trial name
- NCT04622293
- Testing
- Solriamfetol Oral Tablet [Sunosi]
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Rochester Center for Behavioral Medicine
Chronic Fatigue Syndrome
Structural Problems in Brainstem and Cervical Spine Cord in ME/CFS
A case control study on patients with ME/CFS and healthy controls on prevalence of cervical obstructions, Cerebro spinal fluid (CSF) pressure and laboratory findings.
- Trial name
- NCT04403854
- Testing
- MRI, Spinal Tap
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bragee Clinics
Muscle Weakness, Muscle; Fatigue, Heart
The Impact of Beef on Muscle Fatigue in Older Adults
The goal of this controlled-feeding cross-over diet intervention is to compare a beef diet to a vegetarian diet on muscle fatigue in older adults.
- Conditions
- Muscle Weakness, Muscle; Fatigue, Heart, Older Adults
- Trial name
- NCT05860088
- Testing
- Beef Diet, Vegetarian Diet
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University
Muscle Weakness
Investigation the Effect of Rectus Abdominis and Erector Spinae Muscle Fatigue on the Viscoelastic Properties of Thoracolumbal Fascia
The rectus abdominis, which enables the trunk to flex with its activation, and the erector spinae muscles, which provide trunk extension with its activation, are among the structures located in the core region and involved in the…
- Trial name
- NCT06432062
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Fibromyalgia, Irritable Bowel Syndrome
Welfare Benefits in Functional Somatic Disorders
The objective of this observational study is to estimate the number of weeks of welfare benefits, i.e. sickness benefit, unemployment benefit and social assistance, for individuals with functional somatic disorders and compare…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome, Bodily Distress Syndrome
- Trial name
- NCT05611606
- Volunteers
- 9,656 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Muscle Soreness, Muscle Fatigue
Effect of Inhaled Molecular Hydrogen on Recovery Process After Downhill Walking on the Treadmill
This study assesses the effect of molecular hydrogen inhalation in healthy males on muscle soreness, fatigue, oxidative stress, and inflammation following eccentric muscle contraction during downhill walking on the treadmill.
- Conditions
- Muscle Soreness, Muscle Fatigue, Oxidative Stress, Inflammation
- Trial name
- NCT05982665
- Testing
- Molecular hydrogen
- Where
- Czechia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Palacky University
Healthy Young Women, Basketball Players
Perturbation Based Neuromuscular Training Effects on Peroneal Strength, Fatigue and Functional Performance Parameters
In the literature neuromuscular exercise programs are often used for prevention in sport players. Literature lacks of perturbation exercises and its effects on peroneal's muscle strength, fatigue and individual's performance…
- Trial name
- NCT05594628
- Testing
- Neuromuscular training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Muscle Soreness
The Effects of Swedish Massage and Manual Lymph Drainage on Muscle Fatigue
12 healthy men aged 18-30 will be included in the study. Participants will be selected from students who regularly train and do active sports at the Faculty of Sports Sciences. All participants will do nordic hamstring exercise.
- Trial name
- NCT06112899
- Testing
- Nordic Hamstring Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Reducing Orthostatic Intolerance With Oral Rehydration in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
We and others have shown that many younger patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) have orthostatic intolerance (OI), i.e., they can't tolerate prolonged standing.
- Conditions
- Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, Systemic Exertion Intolerance Disease (SEID), Postural Tachycardia Syndrome (POTS)
- Trial name
- NCT02854683
- Testing
- Normal Saline, Oral Rehydration Solution
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- New York Medical College
Fatigue Recovery, Physical Exertion
Cluster Versus Traditional Plyometric Training in Young Soccer Players
The purpose of this study is to compare the effects of two different plyometric training methods (cluster sets versus traditional sets) on young male soccer players.
- Conditions
- Fatigue Recovery, Physical Exertion, Muscle Fatigue
- Trial name
- NCT07843069
- Testing
- Traditional Set Configuration
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Depression, Anxiety
Whole Body Hyperthermia Registry Study
This protocol will allow for the implementation of a research registry pertaining to Whole Body Hyperthermia (WBH) use in various subject populations.
- Conditions
- Depression, Anxiety, PTSD, Fibromyalgia
- Trial name
- NCT02174003
- Testing
- High intensity whole-body infrared heating
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Analysis of Post-exertional Malaise Using a Two-day CPET in People With ME/CFS
This study aims to collect and identify key outcome measures or disease parameters in ME/CFS that are altered during elevated symptoms relative to baseline by gathering information before and after symptom provocation using a…
- Trial name
- NCT04026425
- Testing
- Two-day cardiopulmonary exercise test
- Where
- 3 sites in United States
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Ithaca College
Sleep Disturbance, Fatigue Syndrome, Chronic
Bao Yuan Tang Extract and Galactooligosaccharides for Sleep Regulation
Certain classical formulas in traditional Chinese medicine and dietary prebiotics have demonstrated beneficial effects on various aspects of suboptimal health status in previous studies.
- Conditions
- Sleep Disturbance, Fatigue Syndrome, Chronic, Endocrine Disorder, Glucose Metabolism Disorder
- Trial name
- NCT07774897
- Testing
- Combination product (Bao Yuan Tang full-component extract 2.0g and galactooligosaccharides 2.0g), Galactooligosaccharides 2.0g
- Where
- 6 sites in China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Fibromyalgia, Force Measurement
Evaluation of Fingertip Precision Pinch Force in Fibromyalgia Patients
This study aims to evaluate the force used by fibromyalgia patients during a task compared to healthy volunteers and to evaluate its relationship with fatigue seen in these patients.
- Conditions
- Fibromyalgia, Force Measurement, Isokinetic, Muscle Strength
- Trial name
- NCT06825195
- Testing
- isokinetic muscle strength measurement, Minimum pinch force measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Dilara Ekici Zincirci
Breast Cancer, Chronic Fatigue Syndrome
Monitoring of Chronic Conditions in Breast Cancer
REBECCA-1 is an observational study. Clinical research is undergoing a revolutionary change. The use of electronic patient records (EHR), digital registers, smartphones etc will create "real-world data" (RWD) that provides great…
- Trial name
- REBECCA-1 (NCT05587777)
- Where
- Norway
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Acupressure, Fatigue Syndrome, Chronic
The Effect of Acupressure on Fatigue in Individuals With Chronic Fatigue Syndrome
Chronic fatigue syndrome is a common problem in society. The treatment of this problem is limited. Acupressure is a treatment method that has become widespread and promising in recent years.
- Conditions
- Acupressure, Fatigue Syndrome, Chronic, Complementary Therapies, Quality of Life
- Trial name
- NCT04435002
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital