Clinical trials: Neuropathy;Peripheral
Chronic Low Back Pain, Diabetic Peripheral Neuropathy
MR(Magnetic Resonance) Imaging of Neurotransmitters in Chronic Pain
This study is designed to assess: Hypothesis #1: That there is a significant central pain component in a distinct subset of patients diagnosed with knee osteoarthritis(KOA), Chronic low back pain(CLBP), painful diabetic…
- Conditions
- Chronic Low Back Pain, Diabetic Peripheral Neuropathy, Knee Osteoarthritis
- Trial name
- NCT01620775
- Testing
- MRIs, Pain testing
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pain, Acute, Pain, Neuropathic
Exercise and Pain in Non-Hispanic Blacks and Whites
Non-Hispanic Blacks tend to report higher levels of pain, experience pain more frequently, and be under-treated for pain compared to non-Hispanic Whites.
- Conditions
- Pain, Acute, Pain, Neuropathic, Analgesia, Aerobic Exercise
- Trial name
- NCT03609957
- Testing
- Aerobic Exercise Training, Interval Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Georgia State University
Diabetic Peripheral Neuropathy (DPN)
Clinical Study of Zuogui Jiangtang Shuluo Formula in Treating Diabetic Peripheral Neuropathy
Diabetic peripheral neuropathy (DPN) is a common complication of type 2 diabetes mellitus, affecting 35%-50% of diabetic patients.
- Trial name
- NCT07771894
- Testing
- Zuogui Jiangtang Shuluo Formula, Mecobalamin
- Where
- China
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Peripheral Neuropathy
Neurotoxic Health Hazards of Long-Term Low-Level Exposure to Organophosphate (OP) Compounds in in Hula Valley
During 1987-1991, WHO supported studies of exposures and short term neurobehavioral effects in a cohort (n=200) with occupational and community exposures to pesticide drift containing organophosphates from orchards and cotton…
- Trial name
- NCT00671866
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
Carpal Tunnel Syndrome
Splinting After Mini-Open Carpal Tunnel Release
The purpose of this study is to determine if any difference exists among 3 different postoperative splinting regimens- no splint, removable splint, and plaster non-removable splint- following mini-open carpal tunnel release (CTR)…
- Trial name
- NCT02885701
- Testing
- No Splint, Removable Splint, Non-removable Splint
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Anthony L. Logli
Neuropathic Pain, Pain
Optimized Programming in Spinal Cord Stimulation (SCS) System
The objective of this study is to evaluate extent, location, and perception of paresthesia as a function of anode/cathode configuration.
- Trial name
- OP (NCT00871819)
- Testing
- Precision Spinal Cord Stimulation (SCS)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Cervicobrachial Neuralgia
Longitudinal Experimental Study on ULNTT and Cervico-Thoracic Spine Motion Patterns Relationship
Study Design: Longitudinal Experimental Study Objective: Analyze the relationship between Upper Limb Neural Tension Test (ULNTT1) and cervico-thoracic spine biomechanics using a new motion-capture spine movement data analyzing…
- Trial name
- NCT02632357
- Testing
- Spinal Manipulation
- Where
- Italy
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Tuberous Sclerosis, Neurofibromatoses
Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)
This study is a prospective, randomized, double-blind, placebo-controlled evaluation of the safety of a topically applied formulation of rapamycin to cutaneous fibromatous lesions in subjects with Tuberous Sclerosis Complex (TSC)…
- Conditions
- Tuberous Sclerosis, Neurofibromatoses, Angiofibroma, Neurofibroma
- Trial name
- NCT01031901
- Testing
- Skincerity, Skincerity plus sirolimus/rapamycin, Skinercity plus sirolimus/rapamycin
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Amyotrophic Lateral Sclerosis, Muscular Dystrophy
Innovative Ultrasound Technology in Neuromuscular Disease
This study is utilizing ultrasound measurement to measure neuromuscular disease status in adult patients. The hypothesis is the by quantifying ultrasound data, it is possible that ultrasound can be utilized as a tool to determine…
- Conditions
- Amyotrophic Lateral Sclerosis, Muscular Dystrophy, Radiculopathy, Myopathy
- Trial name
- AQUIRe (NCT02104921)
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Diabetic Peripheral Neuropathy
Strength And Balance Training on Diabetic Peripheral Neuropathy
A Randomized Control Trial was conducted on 20 participants, equally allocated in strength plus balance and aerobic group from February-2020 until December-2020.Participants were selected according to inclusion and exclusion…
- Trial name
- NCT04807452
- Testing
- Strength and balance training, Aerobics training
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Amyloid, Cardiac Amyloidosis
Pan-Amyloid PET/CT in Various Amyloid-Related Disease
To evaluate the potential usefulness of 18F-92/AV45/TPZA/FT8, 11C-PIB positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various Pan-Amyloid-related disease patients.
- Conditions
- Amyloid, Cardiac Amyloidosis, Amyloidosis
- Trial name
- NCT07130565
- Testing
- 18F-92/AV45/TPZA/FT8, 11CPIB
- Where
- 3 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Carpal Tunnel Syndrome
Phonophoresis, Low-Level Laser Therapy and Exercise in the Treatment of Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral nerve compression syndrome. There is insufficient evidence about the efficacy and superiority of conservative treatment methods.
- Trial name
- NCT05213819
- Testing
- Carpal Tunnel Syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Motor Neuropathy
Stroke Recovery Research Based on EEG-fMRI
This study is aimed to investigate the post-stroke motor recovery of patients with ischemic stroke based on their neural features extracted from EEG-fMRI data.
- Trial name
- EEG-fMRI (NCT05427422)
- Testing
- MRI recording, EEG recording
- Where
- China
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Peripheral Nerve Injuries
Mirror Therapy Integrated With Electrical Stimulation for Cortical Modulations
Peripheral nerve injury is common and can result in loss of sensation and motor function, reduced quality of life, and prolonged time to return to work.
- Trial name
- NCT06209801
- Testing
- Mirror therapy, Neuromuscular electrical stimulation, Motor imagery
- Where
- 2 sites in Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
GBS Positive, Women in Labor Given Vancomycin for Prophylaxis
Intrapartum Vancomycin for Group B Streptococcus (GBS) Prophylaxis
While it is clear that intrapartum antibiotics reduce neonatal GBS infection rates, the mechanism by which these drugs prevent neonatal GBS is not well established.
- Trial name
- NCT02143154
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Piriformis Syndrome, Pes Planus
Investigation of the Relationship Between Pes Planus and Piriformis Syndrome: A Case-Control Study
The aim of this study is to investigate the relationship between Pes Planus and Piriformis Syndrome. The study will be conducted on individuals aged 18-65 years who are native Turkish speakers, have Turkish reading and writing…
- Trial name
- Piriformis (NCT07674433)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Carpal Tunnel, Carpal Tunnel Syndrome (CTS)
Efficacy of Dorsal Kinesio Tape Application for Carpal Tunnel Syndrome in Esports Gamers: A Randomized Clinical Trial
This clinical trial investigates the effectiveness of Kinesio Tape (KT) in alleviating carpal tunnel-like symptoms and enhancing gaming performance among young adult PC gamers.
- Trial name
- NCT06993090
- Testing
- Kinesio Tape
- Where
- 3 sites in United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Neuropathy;Peripheral, Thermal Hypesthesia
Effect of Topical Lidocaine on Warm and Cold Sensation in Healthy Individuals
The purpose of the present study is to systematically test the occurrence of paradoxical and illusory responses to cold and warm stimuli in healthy volunteers with artificial sensory loss.
- Trial name
- NCT04865185
- Testing
- Xylocaine spray 100mg/ml, Ethanol
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Neuropathy; Peripheral, Autonomic, in Diabetes Mellitus (Manifestation)
The Relationship Between Vascular Adhesion Protein-1 and Diabetic Cardiovascular Autonomic Neuropathy
Exploring the relationship between serum VAP-1 and cardiovascular autonomic neuropathy in subjects with type 2 diabetes mellitus
- Trial name
- NCT01706289
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Carpal Tunnel Syndrome (CTS)
Diadynamic Current and Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS), first described by Paget in 1854, is the most common entrapment neuropathy. Conservative treatment approaches are prioritized in patients with mild to moderate CTS.
- Trial name
- NCT07356648
- Testing
- Diadynamic Current, Wrist Splint
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duzce University