Clinical trials: Neuropathy (Disorder)
Carpal Tunnel Syndrome (CTS), Median Nerve
The Effectiveness of Neurodynamic Mobilization in Carpal Tunnel Syndrome
This randomized, clinical, single-blinded, controlled study will initially planned to include 86 patients diagnosed with carpal tunnel syndrome who applied to Kütahya Health Sciences University, Evliya Çelebi Training and…
- Trial name
- NCT06882707
- Testing
- Median Nerve Mobilization, Ultrasound therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people
- Sponsor
- Kutahya Health Sciences University
Carpal Tunnel Syndrome
Effectiveness of Ultrasound Guided Hydro-dissection of Median Nerve in Carpal Tunnel Syndrome
60 patients with carpal tunnel syndrome will undergo ultrasound guided hydrodissection of the median nerve with follow up using Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) at 3, 6 and 12 months
- Trial name
- NCT05204992
- Testing
- ultrasound guided hydrodissection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Carpal Tunnel Syndrome (CTS)
Ultrasound-Guided Dextrose Hydrodissection of the Median Nerve
The goal of this clinical trial is to evaluate the clinical and ultrasonographic outcomes of ultrasound-guided median nerve hydrodissection with 5% dextrose in patients with mild and moderate carpal tunnel syndrome.
- Trial name
- NCT07371221
- Testing
- Ultrasound-Guided Median Nerve Hydrodissection with 5% Dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Dr. Nafiz Korez Sincan State Hospital
Manual Therapy, Extracoropral Shock Wave Therapy
Effectiveness of Manual Therapy and Extracoropral Shock Wave Therapy in Patients With Carpal Tunnel Syndrome
This study aimed to compare the effectiveness of manual therapy and extracorporeal shock wave therapy in patients with mild to moderate carpal tunnel syndrome.
- Conditions
- Manual Therapy, Extracoropral Shock Wave Therapy, Carpal Tunnel Syndrome
- Trial name
- NCT07074509
- Testing
- Manual therapy, Extracorporeal shock wave therapy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Tanta University
Diabetic Foot Ulcer
Efficacy and Safety Study of Dermal-Living Skin Replacement to Treat Diabetic Foot Ulcers
The purpose of this study is to test the efficacy and side effects, if any, of Dermal - LSR combined with standard treatment. We hypothesize the treatment will provide beneficial results for diabetic patients suffering foot…
- Trial name
- NCT00368693
- Testing
- Dermal - Living Skin Replacement (Dermal-LSR)
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Infection, Surgical Site
Use of Real-time Fluorescence Imaging in Diabetic Foot Ulcers: the Impact of Colonization
The study evaluates the efficacy of fluorescence-guided de-colonization in patients with non-infected diabetic foot ulcers. The efficacy will also be compared between those who used artificial dermis and split-thickness skin…
- Trial name
- NCT05873049
- Testing
- MolecuLight
- Where
- Taiwan
- Volunteers
- 210 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Carpal Tunnel Syndrome
Splinting After Mini-Open Carpal Tunnel Release
The purpose of this study is to determine if any difference exists among 3 different postoperative splinting regimens- no splint, removable splint, and plaster non-removable splint- following mini-open carpal tunnel release (CTR)…
- Trial name
- NCT02885701
- Testing
- No Splint, Removable Splint, Non-removable Splint
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Anthony L. Logli
Diabetic Foot, Gangrene; Limb
MetaMet: Bone Cutter Versus Bone Saw for Ray Amputation
Toe amputation is a commonly performed operation for infection and/or ischaemia (tissue death due to lack of blood flow). However, a large number of patients having this surgery ultimately require further amputation due to poor…
- Conditions
- Diabetic Foot, Gangrene; Limb, Wound Infection, Wound Healing Delayed
- Trial name
- MetaMet (NCT05804565)
- Testing
- Bone Saw, Bone Cutter
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University College Hospital Galway
Non Small Cell Lung Cancer (NSCLC), Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Study of PX-866 and Docetaxel in Solid Tumors
Phase 1: To determine the maximally tolerated dose (MTD) or recommended dose (RD) and any potential efficacy of PX-866 in combination with docetaxel in patients with solid tumors.
- Trial name
- NCT01204099
- Testing
- Docetaxel, PX-866
- Where
- 33 sites in United States, Canada
- Volunteers
- 223 people
- Sponsor
- Cascadian Therapeutics Inc.
Lumbar Radiculopathy
Comparative Effects of Dynamic Stretching Versus Slider Neurodynamic Technique In Patients With Lumbar Radiculopathy
This study will be a randomised clinical trial conducted at the University of Lahore Teaching Hospital, Lahore, Pakistan. A total of 72 participants will be selected and randomly allocated into two treatment groups (36…
- Trial name
- NCT07384832
- Testing
- Dynamic stretching, slider neurodynamic mobilization, Routine physiotherapy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Type 2 Diabetes Mellitus, Diabetic Peripheral Neuropathy
Evaluation of Exenatide in Patients With Diabetic Neuropathy
This study will look at whether or not the medication exenatide improves signs and symptoms of diabetic peripheral neuropathy in people with type 2 diabetes and mild to moderate diabetic peripheral neuropathy.
- Trial name
- NCT00855439
- Testing
- Exenatide, Glargine
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Michigan
Diabetic Foot Ulcer, Peripheral Arterial Disease
A Non-significant Risk Clinical Study of Therapeutic Ultrasound for Patients With Diabetic Foot Ulcers.
This study is evaluating whether a therapeutic ultrasound device can improve blood flow to the leg with diabetic foot ulcer (DFU).
- Conditions
- Diabetic Foot Ulcer, Peripheral Arterial Disease, Wound; Foot
- Trial name
- Dulcet (NCT05145439)
- Testing
- VibratoSleeve Therapeutic Ultrasound Device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Vibrato Medical, Inc.
Hereditary Spastic Paraplegia, Spastic Paraplegia Type 11
Trehalose Administration in Subjects With Spastic Paraplegia 11 (3AL-SPG11)
Hereditary spastic paraparesis type 11 (SPG11) is caused by mutations in the SPG11 gene that produces spatacsin, a protein involved in lysosomal function.
- Trial name
- 3AL-SPG11 (NCT04912609)
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- IRCCS Fondazione Stella Maris
Carpal Tunnel Syndrome
Serum GDF-15 in Carpal Tunnel Syndrome
This observational study aims to evaluate serum Growth Differentiation Factor-15 (GDF-15) levels in patients with idiopathic carpal tunnel syndrome compared with asymptomatic controls.
- Trial name
- NCT07791316
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Diabetes Mellitus, Diabetic Foot Disease
Gremlin-1 and Wagner Classification: Potential Biomarker for Amputation in Diabetic Foot Patients
The aim of the approach to diabetic foot patients is to heal the wound, mobilize the patient, increase the quality of life, and reduce DA-related amputations as much as possible.
- Conditions
- Diabetes Mellitus, Diabetic Foot Disease, Diabetic Foot Ulcer, Diabetic Neuropathy
- Trial name
- NCT06753604
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Seyma Acik
Peripheral Neuropathy
Multimodal Ultrasound in Peripheral Neuropathy
This study will enforce the role of ultrasound in early diagnosis and screening on peripheral neuropathy in comparison with other modalities.
- Trial name
- NCT06711133
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetic Foot
Diabetic Foot Ulcer Prevention System
To evaluate a recently developed non-invasive infrared thermal camera called Diabetic Foot Ulcer Prevention System (DFUPS) in a clinical setting by studying healthy volunteers.
- Trial name
- DFUPS (NCT02317835)
- Testing
- DFUPS
- Where
- 3 sites in United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Carpal Tunnel Syndrome
Investigation of the Efficiency of Radial Extracorporeal Shock Wave Therapy at Different Pulses in Carpal Tunnel Syndrome
Different parameters have been used in studies investigating the efficacy of extracorporeal shock wave therapy in the treatment of carpal tunnel syndrome.
- Trial name
- NCT06321276
- Testing
- extracorporeal shockwave therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Ahi Evran University Education and Research Hospital
Cerebral Necrosis, Nashopharyngeal Cancer
Treatment of Cerebral Radiation Necrosis (CRN) With Nerve Growth Factor (NGF)
Cerebral radiation necrosis (CRN) is a well-documented late complication of radiation therapy for cancers, and may have a devastating effect on the patient's quality of life (QOL).
- Conditions
- Cerebral Necrosis, Nashopharyngeal Cancer, Nerve Growth Factor
- Trial name
- NCT02032147
- Testing
- NGF group
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Fudan University
Chemotherapy-Induced Peripheral Neuropathy (CIPN), Breast Cancer
Web-Based Exercise for Neuropathy and Quality of Life in Breast Cancer
Chemotherapy is a widely used treatment method for cancer patients. However, various side effects may occur depending on the drug used, treatment duration, and dosage.
- Trial name
- NCT06879678
- Testing
- Web-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
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