Clinical trials: Neuroplasticity in Motor Learning
Cerebral Palsy
BeFAST or BeSTRONG: Brain Change After Fun Athletic Sports-skill Training or Brain Change After Strength TRaining Focusing ON Gait
The purpose of this study is to compare a motor learning (ML)-based gait-related training intervention to a functional lower limb strength training intervention, with a concurrent evaluation of functional, neural and…
- Trial name
- NCT02754128
- Testing
- BeFAST, BeSTRONG
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Parkinson
Improving Walking With Heel-To-Toe Device
Introduction: The purpose of this study is to test the efficacy potential of using real-time positive auditory feedback to improve gait pattern in people with Parkinson's Disease (PD).
- Trial name
- NCT04300348
- Testing
- Heel2Toe, No-feedback control group
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- McGill University
Neuroplasticity in Motor Learning
Neuroplasticity in Motor Learning in Young Adults Under Variable and Constant Practice Conditions
The project aims at providing a better understanding of motor skill acquisition and learning processes. The primary objectives of the study are to determine how practice conditions, i.e., variable and constant practice…
- Trial name
- NMLPC (NCT04921072)
- Testing
- Constant practice conditions, Variable practice conditions
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Cerebrovascular Stroke
Fast Arm Motor Skill Training in Chronic Stroke Survivors
Every year, almost 800,000 people experience a stroke in the United States, which lead to upper-limb impairments, making recovery of motor function a priority in stroke rehabilitation.
- Trial name
- FAST (NCT05013762)
- Testing
- Fast intervention, Active Monitoring
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Southern California
Stroke
Potentiation of Procedural Motor Learning in Health and Disease
The investigators plan to improve the learning of motor skills by pharmacological means (dopamine), and by noninvasive brain stimulation. They will study both healthy subjects and chronic stroke patients.
- Trial name
- NCT00126087
- Testing
- dopamine
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Parkinson Disease
Facilitating Motor Skill Learning in Parkinson's Disease III
The study is designed to assess the effects of cardiovascular (aerobic) exercise on motor skill learning in Parkinson patients. Specifically, the investigators examine whether moderate-intense aerobic exercise, performed…
- Trial name
- FaST-PD-III (NCT04653285)
- Testing
- motor skill practice, aerobic exercise, rest
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University of Erlangen-Nürnberg
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Comparison of Synchronous and Asynchronous Action Observation Therapy in Children With Cerebral Palsy
The aim of this study is to compare the effects of synchronous and asynchronous action observation therapy (AOT) on balance, gait, and functional capacity in children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy, Neurodevelopmental Disorder (Diagnosis)
- Trial name
- NCT07114731
- Testing
- Synchronous Action Observation Therapy, Asynchronous Action Observation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Istanbul University - Cerrahpasa
Aging, Music
Brain Imaging and Behavioural Changes Following Cued-movement Training of Finger Sequences in Healthy Older Adults
The goal of this study is to examine changes in the brain, behavior, and personal experience when music is used to guide learning of finger movement sequences (compared to visual stimuli alone) in healthy older adults.
- Conditions
- Aging, Music, Motor Activity, Magnetic Resonance Imaging
- Trial name
- NMSOA (NCT06174740)
- Testing
- Music-cued audiovisual motor training, Visually-cued motor training
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universiteit Leiden
Parkinson Disease
Facilitating Motor Skill Learning in Parkinson's Disease II (FaST-PD II)
The study is designed to assess the effects of cardiovascular (aerobic) exercise on motor skill learning in Parkinson patients. Specifically, the investigators examine whether a single bout of moderate-intense aerobic exercise…
- Trial name
- FaST-PD II (NCT03886090)
- Testing
- aerobic exercise, rest, motor learning
- Where
- Germany
- Volunteers
- 18 people
- Sponsor
- University of Erlangen-Nürnberg
Parkinson Disease
Exploring the Effects of Exercise on Memory and Cognition in Parkinson´s Disease
The study aims to assess the effects of cardiovascular (aerobic) training on memory formation and cognitive function in people with Parkinson's disease.
- Trial name
- EMCo (NCT06580977)
- Testing
- cardiovascular training, stretching
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Heidelberg University
Healthy Volunteers
Long-Term Improvement in Motor Learning by Transcranial Direct Current Stimulation
This study will examine whether continuous use of transcranial direct current stimulation (tDCS) in combination with motor training can lead to long-term improvement in movement performance beyond what can be achieved with motor…
- Trial name
- NCT00314769
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebral Palsy
Brain Change After Fun, Athletic, Sports-skill Training (BeFAST)
The purpose of this study is to determine the associations between changes in neural activity and structure, advanced gross motor skills, gait characteristics, and physical activity participation following a gait-related…
- Trial name
- BeFAST (NCT02584491)
- Testing
- Functional gait-related training
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cognitive Function, Neuroplasticity
How Cultural Background Affects Cognitive and Motor Learning Using Virtual Reality
This observational study examined how long-term cultural background is associated with differences in cognitive and motor learning within a virtual reality environment.
- Conditions
- Cognitive Function, Neuroplasticity, Motor Skills, Virtual Reality
- Trial name
- NCT07242937
- Testing
- Virtual reality beat saber training and cognitive and motor assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Cerebral Palsy, Walking, Difficulty
A Motor Learning Intervention to Target Walking Performance in Ambulant Children With Cerebral Palsy
The goal of this clinical trial is to learn if a new therapy approach to improve walking ability in children with Cerebral Palsy is acceptable to the children and the families in a community setting.
- Conditions
- Cerebral Palsy, Walking, Difficulty, Spastic Diplegia, Hemiplegic Cerebral Palsy
- Trial name
- MOBILE (NCT06454656)
- Testing
- MOBILE
- Where
- Ireland
- Volunteers
- 14 people
- Sponsor
- Royal College of Surgeons, Ireland