Clinical trials: Neuropsychiatric Systemic Lupus Erythematosus
Neuropsychiatric Systemic Lupus Erythematosus
Magnetic Resonance Spectroscopy, Perfusion, and Diffusion Tensor Imaging in Neuropsychiatric Lupus
The purpose of this study is to determine if three functional Magnetic Resonance brain imaging techniques: Magnetic Resonance Spectroscopy(MRS),Magnetic Resonance perfusion, and Diffusion Tensor Imaging(DTI) can detect brain…
- Trial name
- NCT00730002
- Testing
- Magnetic Resonance Angiography (MRA), Magnetic resonance imaging, MRA
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Michigan
SLE - Systemic Lupus Erythematosus
Pakistan Arthritis and Connective Tissue Disease Network - Systemic Lupus Erythematosus
Systemic lupus erythematosus (SLE) is a complex autoimmune disorder that affects individuals globally, yet there is a significant lack of data regarding its prevalence and management, particularly in Asian populations like…
- Trial name
- PAN-SLE (NCT07902622)
- Testing
- no active ingredient
- Where
- Pakistan
- Volunteers
- 3,000 people
- Sponsor
- Foundation University Islamabad
Systemic Lupus Erythematosus
Neuron-specific Humoral and Cellular Immune Correlates of Structural and Functional Brain Connectomics in Neuropsychiatric Lupus
Systemic lupus erythematosus (SLE) is the prototype systemic autoimmune disease. Neuropsychiatric SLE (NPSLE) is a major cause of morbidity.
- Trial name
- INLES (NCT05880121)
- Testing
- MRI
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele
Systemic Lupus Erythematosus, Fibromyalgia
Magnetic Resonance Spectroscopy, Perfusion and Diffusion Tensor Imaging in Neuropsychiatric Lupus
The purpose of this study is to find out if certain types of Magnetic Resonance (MR) scanning will help to better detect markers in the brain that are related to the neuropsychiatric symptoms of systemic lupus erythematosus…
- Conditions
- Systemic Lupus Erythematosus, Fibromyalgia, Acute Neuropsychiatric Lupus
- Trial name
- NCT00723671
- Testing
- MRI
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Systemic Lupus Erythematosus (SLE), Lupus Nephritis
Lupus Landmark Study: A Prospective Registry and Biorepository
The purpose of the registry and biorepository is to provide a mechanism to store clinical data, linked biospecimens and molecular data to support the conduct of future research on Systemic Lupus Erythematosus (SLE), including…
- Conditions
- Systemic Lupus Erythematosus (SLE), Lupus Nephritis, Neuropsychiatric Systemic Lupus Erythematosus
- Trial name
- NCT05934149
- Where
- 25 sites in United States, Canada
- Volunteers
- 3,500 people
- Sponsor
- Lupus Research Alliance
Systemic Lupus Erythematosus
Libman-Sacks Endocarditis as a Cause of Neuropsychiatric Systemic Lupus Erythematosus
The purpose of this study is to determine whether Libman-Sacks endocarditis (inflammation of the heart valves) is the cause of neuropsychiatric manifestations (stroke, transient ischemic attacks, cognitive dysfunction, seizures…
- Trial name
- NCT00858884
- Testing
- Clinical and laboratory evaluations, transesophageal echocardiography, carotid duplex, transcranial duplex, and magnetic resonance of the brain
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Systemic Lupus Erythematosus
Development of a Novel Glutamate Receptor Ligand for PET Scans in Neuropsychiatric Systemic Lupus Erythematosus
Cognitive impairment occurs in as many as 80% of lupus patients and affective disorders, depression and anxiety, are also common. Both of these problems contribute significantly to disease burden and disability.
- Trial name
- NCT02456168
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Neuropsychiatric Systemic Lupus Erythematosus, Systemic Lupus Erythematosus (SLE)
EG-501 for Cognitive Impairment in Neuropsychiatric SLE (NPSLE): Efficacy and Safety Study
Neuropsychiatric systemic lupus erythematosus with cognitive impairment (NPSLE-CI) is a serious, disabling, and potentially life-threatening manifestation of SLE, affecting up to 80% of patients with cognitive impairments ("brain…
- Conditions
- Neuropsychiatric Systemic Lupus Erythematosus, Systemic Lupus Erythematosus (SLE), Cognitive Impairment
- Trial name
- NCT07281105
- Testing
- EG-501
- Where
- 3 sites in United States
- Volunteers
- 131 people
- Sponsor
- Evergreen Therapeutics, Inc.