Clinical trials: Neurorehabilitation
Stroke, Gait, Hemiplegic
Comparing Effects of Conventional Neurorehabilitation With Exoskeleton With High-intensity Gait Training
The purpose of this research is to compare improvements between the rehab intervention with walking practice using the robotic exoskeleton versus walking practice that is vigorous enough to keep participants' heart rate over a…
- Trial name
- NCT06478680
- Testing
- Exoskeleton mediated gait training, High intensity gait training
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Alvernia University
Spinal Cord Injuries
Effectiveness of NEUROM and tDCS for Motor Recovery in Chronic Paraplegia
Traumatic Spinal Cord Injury (TSCI) is a catastrophic, unexpected, and devastating event that can occur along the spinal column (cervical, thoracic, and lumbar).
- Trial name
- NEUROM (NCT04790149)
- Testing
- Conventional Rehabilitation, NEUROM + tDCS, NEUROM
- Where
- Lebanon
- Volunteers
- 56 people
- Sponsor
- Lebanese University
Multiple Sclerosis
Illuminating New Paths in the Treatment of Multiple Sclerosis Relapses - Early and Specialized Rehabilitation
The overall purpose of this project is to develop and test an infrastructure that can ensure early and specialized rehabilitation for individuals with multiple sclerosis (MS) on their path to recovery from a relapse.
- Trial name
- MS_Early_Rehab (NCT06956326)
- Testing
- Intensive rehab, Usual care
- Where
- 2 sites in Denmark
- Volunteers
- 64 people
- Sponsor
- Lars Hvid
Parkinson Disease, Virtual Reality
Upper Extremity Rehabilitation With Virtual Reality in Parkinson's Disease Patients
Upper extremities are the first part of the body to be affected by Parkinson's disease. Although studies have shown that virtual reality-assisted rehabilitation methods are effective on gait and balance, studies on their use for…
- Conditions
- Parkinson Disease, Virtual Reality, Neurological Rehabilitation, Upper Extremity Dysfunction
- Trial name
- NCT06147726
- Testing
- Upper extremity position matching exercises in virtual reality, Conventional physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ramazan KURUL
Stroke
Unsupervised Therapy After Stroke in the Home Setting With a Hand Rehabilitation Device (ReHandyBot)
The ReHandyBot is a robot for hand rehabilitation after stroke. The aims of this study are (1) to investigate the feasibility of unsupervised therapy with the ReHandyBot with stroke inpatients, first in a rehabilitation clinic…
- Trial name
- NCT06057129
- Testing
- Supervised and minimally-supervised therapy with ReHandyBot, Unsupervised therapy
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Swiss Federal Institute of Technology
Robot-aided Arm Therapy, Brain Injury, Motor Relearning Programme, Activities of Daily Living
Robot-Aided Neurorehabilitation of the Upper Extremities
Task-oriented repetitive movement can improve movement performance in patients with neurological or orthopedic lesions. The application of robotics can serve to assist, enhance, evaluate, and document neurological and orthopedic…
- Trial name
- NCT02434237
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Multiple Sclerosis
Bilateral Anodal Cerebellar tDCS for Multidomain Dysfunctions in Patients With Multiple Sclerosis
The goal of this clinical trial is to learn if brain stimulation can improve movement and daily function in people with multiple sclerosis (MS).
- Trial name
- CerebellertDCS (NCT07555379)
- Testing
- Bilateral Cerebellar Transcranial Direct Current Stimulation (ctDCS)
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- University of Sharjah
Ischemic Stroke
Robot-Assisted Gait Therapy in the Subacute Phase of First Ischemic Stroke
Robot-assisted gait training (RAGT) represents a modern concept of neurorehabilitation in stroke patients. This single-center randomized parallel-group neurorehabilitation trial with blinded primary outcome assessment is aimed at…
- Trial name
- NCT04910217
- Testing
- Conventional rehabilitation, Leg/lower body exerciser device intervention., Lokomat intervention
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- University Hospital Ostrava
Parkinson Disease
Triggering Motor Memory Consolidation in PD: Complex Practice of Fine Motor Tasks and Brain Activity During Learning
Parkinson's disease (PD) is characterized by severe motor symptoms, including upper limb dysfunction, that is only partially alleviated by medication.
- Trial name
- NCT04269590
- Testing
- Dual Task (DT) training, Single Task (ST) training
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Parkinson s Disease
Comparison of Immersive and Non-Immersive Virtual Reality Rehabilitation in Parkinson's Disease
Parkinson's disease commonly affects walking ability, balance, mobility, and cognitive function, increasing the risk of falls and reducing independence.
- Trial name
- VR-PD (NCT07659288)
- Testing
- Immersive Virtual Reality, Non-Immersive Virtual Reality
- Where
- Chile
- Volunteers
- 16 people
- Sponsor
- Neuro Group XR Inc.
Stroke
iTMS - Implementing Transcranial Magnetic Stimulation (TMS) to Assess Cortico-spinal Tract Integrity
Reliable prediction of upper limb (UL) function can guide clinicians in choosing relevant treatment, helps to set realistic goals for rehabilitation and will contribute to personalized and effective rehabilitation.
- Trial name
- iTMS (NCT06153017)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Chronic Cerebral Ischemia
Safety and Efficacy of Sequential Therapy With Mexidol® in Patients With Chronic Cerebral Ischemia
The purpose of this study is to evaluate safety and efficacy of sequential treatment with Mexidol® in patients with chronic cerebral ischemia (CCI).
- Trial name
- MEMO (NCT06834490)
- Testing
- Mexidol
- Where
- 14 sites in Russia, Uzbekistan
- Volunteers
- 318 people
- Sponsor
- Pharmasoft
Cerebrovascular Stroke
Fast Arm Motor Skill Training in Chronic Stroke Survivors
Every year, almost 800,000 people experience a stroke in the United States, which lead to upper-limb impairments, making recovery of motor function a priority in stroke rehabilitation.
- Trial name
- FAST (NCT05013762)
- Testing
- Fast intervention, Active Monitoring
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Southern California
Human Immunodeficiency Virus, Cognitive Dysfunction
Computerized Cognitive Rehabilitation of Patients With Cognitive Deficits Due to the Human Immunodeficiency Virus
WHO: 24 participants with cognitive deficits due to a Human Immunodeficiency Virus (HIV) infection, able to engage in moderate physical activity.
- Trial name
- NCT06603727
- Testing
- Computerized Gaming Rehabilitation Program 1, Computerized Gaming Rehabilitation Program 2
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Multiple Sclerosis, Functional Neurological Disorders
Bridging Gaps in the Multidimensional Assessment and Management of Overlapping Symptoms in Multiple Sclerosis and Functional Motor Disorders: Prevalence and Rehabilitation Effectiveness
Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system that may cause a broad range of motor and non-motor symptoms.
- Trial name
- NCT07856485
- Testing
- Functional Motor Disorder-Specific Multidisciplinary Rehabilitation, Conventional Multiple Sclerosis Rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 192 people
- Sponsor
- IRCCS San Raffaele
Rehabilitation, Neurologic Disorder
The Experience in Neurorehabilitation Setting: a Qualitative Study
In this exploratory qualitative study with a hermeneutic phenomenological approach, we will describe and understand the experience of treatment and hospitalization in hospitalized people suffering from stroke, multiple sclerosis…
- Conditions
- Rehabilitation, Neurologic Disorder, Stroke, Parkinson Disease
- Trial name
- NURSEXPERIENCE (NCT06264037)
- Testing
- semi structured interview
- Where
- 3 sites in Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Cervical Spinal Cord Injury
Efficacy of a Brain-Computer Interface Controlled Functional Electrical Stimulation Therapy for Spinal Cord Injury Neurorehabilitation
The study's main goal is to determine the efficacy of a therapy with brain-computer interface controlled functional electrical stimulation for neurorehabilitation of spinal cord injury patients' upper limbs.
- Trial name
- NCT05343130
- Testing
- Brain-Computer Interface
- Where
- Mexico
- Volunteers
- 32 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Acquired Brain Injury Including Stroke, TBI
Effects of Neurofeedback Training and tRNS on Attentional Deficits in Patients With Acquired Brain Injury
The goal of this study is to investigate new neuromodulation therapies for attention deficits following acquired brain injury. Brain damage can affect various domains, including motor and cognitive functions.
- Conditions
- Acquired Brain Injury Including Stroke, TBI, Stroke, Anoxia-Ischemia, Brain
- Trial name
- NeMoRe II (NCT07817316)
- Testing
- verum tRNS + Neurofeedback
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospitales Nisa
Cerebral Palsy, Spastic Dysarthria
Application of Vibration Wave Therapy to the Children Suffering From Cerebral Palsy and Tongue Spastic Dysarthria
Vibration therapy is the widely used in many neurological disorders for different type of problems. Recently, it is being used by researchers for the betterment of motor disorders and muscle movements of the cerebral palsy…
- Trial name
- NCT04222049
- Testing
- Vibro Tactile Gadget
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National University of Science and Technology, Pakistan
Malnutrition
Observational Study at the Influence of Malnutrition on Infections
The purpose of this trial is to determine whether nutritional status has an impact on nosocomial infections. Study population are patients undergoing early neurological rehabilitation.
- Trial name
- Malnutrition (NCT01243528)
- Testing
- Laboratory values
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Marion Mertl-Roetzer