Clinical trials: Neurorehabilitation
Spinal Cord Injury, Spinal Cord Injury Cervical
Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury
Stimulation of the spinal cord and brain represents a new experimental therapy that may have potential to restore movement after spinal cord injury.
- Trial name
- NCT06867809
- Testing
- Epidural spinal cord stimulation and paired spine and brain stimulation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Jason Carmel
Spinal Cord Injuries
Effects of Paired Associative Nerve Stimulation on Spinal Cord Injury Subjects
This study is to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) combined with trans-spinal electrical stimulation (tsES) intervention on cortical excitability, brain structure, motor ability of…
- Trial name
- NCT04194099
- Testing
- 20 Hz rTMS (Brain), iTBS rTMS (Brain), Anode tsDCS (Spinal)
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Taipei Medical University Hospital
Poststroke/CVA Hemiparesis, Paralytic Stroke
BCI Post-stroke Neurorehabilitation
The goal is to evaluate the potential of a EEG based BCI (Brain-Computer-Interface) connected to a non-invasive pneumatic glove for rehabilitation of hand-movements post-stroke.
- Conditions
- Poststroke/CVA Hemiparesis, Paralytic Stroke, Hand Flaccid Paralysis
- Trial name
- BCI-stroke (NCT02404857)
- Testing
- EEG based Brain Computer Interface
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Stroke
Is the Rehabilitation Robotic a Safe and Effective Choice for Stroke Patients?
The effectiveness of robotic over conventional therapy is arguable and the best therapy strategy is still not clear. Basing on the existing evidence on motor learning and practice-induced neuroplasticity, the investigators plan…
- Trial name
- NCT03290833
- Testing
- Robotic, Conventional therapy
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Ten-Chen General Hospital
Stroke
Mirror Therapy: Effects on Functional Recuperation of Severe Upper Limb Paresis After Stroke
After stroke, patients frequently suffer from arm or hand weakness. There are numerous rehabilitation methods to stimulate recovery, amongst which mirror therapy (MT).
- Trial name
- MT (NCT02949609)
- Testing
- Mirror Therapy, Control Therapy
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University Hospital, Geneva
Stroke, Brain Computer Interface
BCI for Hemiparetic Upper Extremities in Patients Due to Stroke
Non-invasive brain-computer interface (BCI) technology is one of the new training approaches to achieve motor restoration through a closed-loop system from brain activity through event-related desynchronization (ERD) after motor…
- Trial name
- NCT05778448
- Testing
- Brain Computer Interface/ Functional Electrical Stimulation/ Virtual Reality
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke
Powered Orthotic Exoskeleton Training in Stroke
Veterans who suffer strokes often have disturbances in the ability to walk that reduces independence and quality of life. Alterations in gait combined with general decreased activity are associated with reduced muscle strength of…
- Trial name
- POETS (NCT04241848)
- Testing
- Keeogo, Ambulation training
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- VA Office of Research and Development
Parkinson's Disease, Physical Activity
Effect of High Intensity Interval Training on Mechanisms of Neuroplasticity in Parkinson's Disease Patients
There are experimental evidences of the important role of high intensity physical exercise in Parkinson's disease (PD) treatment, that induces similar effects to pharmacotherapy.
- Conditions
- Parkinson's Disease, Physical Activity, Neurorehabilitation, Neuroplasticity
- Trial name
- NCT04204551
- Testing
- high-intensity interval training (HIIT), conventional physical therapy
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Multiple Sclerosis
Effectiveness of Exergaming in Adittion to Conventional Treatment for Physical Therapy in People with Multiple Sclerosis
The present study aims to evaluate the effectiveness of two different exergaming systems in addition to conventional treatment on physical functional capacity, balance, muscle strength, spasticity in lower limbs and quality of…
- Trial name
- NCT06196866
- Testing
- Conventional Therapy, Nintendo Ring Fit Adventure + Conventional Therapy, Nintendo Wii Fit + Conventional Therapy
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad de Córdoba
Logoneurosis
Logoneurosis. Complete Remission. Clinical Document No. 001. Family System CITADEL 2060: METHODOLOGY "VOICE OF SLEEP MAMABEE 2026-2085"
Training Modules: Three fairy tales Doctrine "Voice of Sleep: MамаBee 2026-2085" Family System: "Citadel 2060" Systemic work with brain neurons through training modules at the border of sleep in clinical, psychological and…
- Trial name
- MamaBee (NCT07628114)
- Testing
- Voice of Sleep MamaBee 2026-2085 Training Modules: Systemic work with brain neurons through training modules at the border of sleep. Restoration of the nervous system core in real time.
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Pisareva Citadel Group LLC
Stroke, Aphasia
Transcranial Alternating Current Stimulation in Post Stroke Aphasia Therapy
This study aims to investigate the efficacy of transcranial alternating current stimulation (tACS) combined with linguistic training for patients with chronic post-stroke aphasia.
- Trial name
- AfatES (NCT07510464)
- Testing
- active 75 Hz transcranial alternating current stimulation
- Where
- Poland
- Volunteers
- 11 people
- Sponsor
- QVITI S.A.
Acquired Brain Injuries, Spinal Cord Injury
Virtual Reality Rehabilitation for Cognitive, Emotional, and Motor Recovery in Neurological Disorders
This randomized controlled trial (RCT) evaluates the effectiveness of virtual reality (VR) rehabilitation in improving cognitive, emotional, social, and motor functions in patients with neurological disorders (ABI, SCI, MS, PD).
- Conditions
- Acquired Brain Injuries, Spinal Cord Injury, Multiple Sclerosis, Parkinson Disease
- Trial name
- NeuroVR (NCT06838975)
- Testing
- VR Training, traditional cognitive and motor rehabilitation following standard clinical practices
- Where
- 2 sites in Italy
- Volunteers
- 328 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Spinal Cord Injury
AI-Powered Closed-Loop Multielectrode Transcutaneous Spinal Cord Stimulation: Real-Time Adjustments for Enhanced Motor Recovery in Spinal Cord Injury (AIM RECOVER)
Spinal cord injury (SCI) often results in persistent motor deficits that are inadequately addressed by conventional rehabilitation.
- Trial name
- AIM RECOVER (NCT07452133)
- Testing
- Dynamic stimulation, Static stimulation
- Where
- Singapore
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Stroke, Subarachnoid Hemorrhage
MUSic Therapy In Complex Specialist Neurorehabilitation
Aim: Investigate whether patients undergoing specialist rehabilitation after complex neurological injury show different functional outcomes if music therapy is included in their rehabilitation program compared to usual care.
- Conditions
- Stroke, Subarachnoid Hemorrhage, Traumatic Brain Injury, Tumor, Brain
- Trial name
- MUSICS (NCT05777499)
- Testing
- Music Therapy, Control Therapy
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University College, London
Parkinson Disease
Predicting Motor Learning of an Upper Limb Task Based on Behavioral and Disease-specific Characteristics in Patients With Parkinson's Disease
Manual dexterity deficits and loss of motor automaticity are commonly seen in patients with Parkinson's disease (PD). Amongst these problems, using a touchscreen is becoming increasingly burdensome.
- Trial name
- NCT06738290
- Testing
- Targeted home-based touchscreen training
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Spinal Cord Injury, Able Bodied
Effects of a Virtual Reality-based Brain-Machine Interface Protocol in Spinal Cord Injury
Spinal cord injury (SCI) is a highly debilitating pathology, associated with the loss of sensorimotor functions, autonomy and quality of life.
- Conditions
- Spinal Cord Injury, Able Bodied, Traumatic Spinal Cord Injuries, Paraplegia, Spinal
- Trial name
- NCT07732868
- Testing
- Brain-Machine Interface
- Where
- 2 sites in Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- José Gabriel da Silva Figueiredo
Brain Injuries, Attention Disorder
Effects of Neurofeedback Training on Attentional Deficits in Patients With Acquired Brain Injury
The goal of this study is to investigate new neuromodulation therapies for attention deficits following acquired brain injury. Brain damage can affect various domains, including motor and cognitive functions.
- Trial name
- NeMoRe (NCT06863025)
- Testing
- Neurofeedback training, Standard cognitive therapy
- Where
- 2 sites in Spain
- Volunteers
- 30 people
- Sponsor
- Hospitales Nisa
Stroke, Aphasia
Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy
This study is designed for individuals with aphasia, a language disorder that affects many stroke survivors, making it difficult to read, speak, and understand language.
- Trial name
- NCT06891638
- Testing
- Schedule of tDCS administration
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Kessler Foundation
Brain Injury, Stroke Patients
Acquired Brain Injury and Neurorehabilitation: the Influence of Psychological Characteristics
Acquired brain damage generates motor, cognitive, behavioral and emotional deficits. Neurorehabilitation aims to reduce these deficits and develop compensatory strategies that increase the person's functionality.
- Conditions
- Brain Injury, Stroke Patients, TBI-Traumatic Brain Injury
- Trial name
- DANEA (NCT06661512)
- Testing
- Neurorehabilitation program
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Institut Guttmann
Stroke
Effects of a Neurorehabilitation Program Based on CIMT and Non-invasive Neuromodulation Through C-tDCS on the Recovery of Paretic Upper Limb Function, Quality of Life, and Therapeutic Alliance in Women From the Araucanía Region Who Suffered a Stroke (CIMT + tDCS).
General Objective To determine the effects of a neurorehabilitation program based on Constraint-Induced Movement Therapy (CIMT) and non-invasive neuromodulation through cerebellar transcranial direct current stimulation (C-tDCS)…
- Trial name
- (CIMT - tDCS) (NCT07619703)
- Testing
- tDCS
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- Universidad de La Frontera