Clinical trials: Neurorehabilitation
Acquired Brain Injury, Balance Disorders
Balance Dimensions-Based Rehabilitation Program in People With Acquired Brain Injury
The purpose of this clinical trial is to find out whether a rehabilitation program based on different dimensions of balance can improve balance, mobility, walking ability, and quality of life in people with acquired brain injury.
- Trial name
- BALANCE-DCA (NCT07696663)
- Testing
- Multimodal Balance Rehabilitation Program, Conventional Physiotherapy
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- University of Castilla-La Mancha
MCI, Mild Cognitive Impairment (MCI)
Prevalence of Mild Cognitive Impairment and Dementia in Patients Admitted to Non-neurological Rehabilitation Wards
Cognitive impairment is common among older adults hospitalized for non-neurological conditions but often goes unrecognized, particularly in rehabilitation settings where clinical attention is mainly focused on physical recovery.
- Conditions
- MCI, Mild Cognitive Impairment (MCI), Mild Cognitive Impairment, Cognitive Deficit
- Trial name
- COGinREHAB (NCT07731334)
- Testing
- Cognitive and clinical screening, Extended neuropsychological assessment, Blood biomarker sampling and APOE genotyping
- Where
- 3 sites in Italy
- Volunteers
- 384 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Spastic Hemiplegia
The Effects of Neurorehabilitation Approaches Involving Different Upper Extremity Reactive Trainings in Stroke Patients
The goal of this clinical trial is to investigate the effectiveness of upper extremity training, which is expected for 5 seconds on the target during reaching forward, and to compare the effectiveness of neurorehabilitation…
- Trial name
- NCT06086314
- Testing
- reactive exercise training with ''FitPodz Light Trainer'' device in addition to a neurorehabilitation program, reactive exercise training with co-contraction with ''FitPodz Light Trainer'' device in addition to a neurorehabilitation program., neurorehabilitation program with functional reaching training without device.
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Pamukkale University
Stroke
Effect of Mirror Therapy Versus Bilateral Arm Training for Rehabilitation After Chronic Stroke
The study purpose is to compare the efficacy of mirror therapy and bilateral arm training on movement strategies of the affected upper extremity and functional outcome in chronic stroke patients.
- Trial name
- NCT02548234
- Testing
- Mirror therapy, Bilateral arm training
- Where
- Taiwan
- Volunteers
- 29 people
- Sponsor
- China Medical University Hospital
Stroke, Executive Dysfunction
Computerized Cognitive Rehabilitation of Executive Deficits in Stroke Patients
WHO: 32 participants with executive deficits related to a stroke, able to engage in moderate physical activity. WHY: Around one third of stroke patients suffer from cognitive deficits in the long term, which have a detrimental…
- Trial name
- NCT05169632
- Testing
- Computerized Gaming Rehabilitation Program 1, Computerized Gaming Rehabilitation Program 2
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Stroke
Effects of Voluntary Adjustments During Walking in Participants Post-stroke
People post-stroke retain the capacity to modify walking patterns explicitly using biofeedback and implicitly when encountering changes in the walking environment.
- Trial name
- NCT06034119
- Testing
- Split belt treadmill, Biofeedback
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Chapman University
Stroke, Neurological Diseases or Conditions
Nineteen Years of Modified CIMT in a Clinical Setting, to Improve Arm and Hand Function After Stroke
The goal of this observational study is to determine if clinically constraint-induced movement therapy (CIMT), when applied in a routine clinical practice, can improve arm- and hand function after stroke.
- Trial name
- NCT06671899
- Testing
- Constraint-induced movement therapy (CIMT)
- Where
- Sweden
- Volunteers
- 87 people
- Sponsor
- Region Jönköping County
Diplegic Cerebral Palsy With Spasticity, Cerebral Palsy, Spastic, Diplegic
Impact of rTMS Combined With Neurorehabilitation on Lower Extremity Motor Function and Spasticity in Children With Spastic Diplegic Cerebral Palsy
Cerebral palsy (CP) is widely recognized as the most prevalent cause of lifelong physical disability emerging in childhood across most global populations.
- Conditions
- Diplegic Cerebral Palsy With Spasticity, Cerebral Palsy, Spastic, Diplegic, Transcranial Magnetic Stimilation, Cerebral Palsy (CP)
- Trial name
- NCT07488429
- Testing
- TMS
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ankara City Hospital Bilkent
Hemiparetic Cerebral Palsy
Using Neurotechology to Help Children With Physical Disability Due to Cerebral Palsy
Hemiparetic cerebral palsy is a condition in which one side of a child's body becomes weak due to brain injury occurring around birth, often caused by stroke.
- Trial name
- NCT07269353
- Testing
- Brain Computer Interface - Functional Electrical Stimulations
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of Alberta
Seated Treadmill Training, Treadmill Locomotor-based Training
Ankle Robotics Training After Stroke
Veterans and other Americans who survive stroke often face disabling motor impairments that impede performance of activities of daily living and limit free-living activity.
- Conditions
- Seated Treadmill Training, Treadmill Locomotor-based Training, Treadmill Only
- Trial name
- NCT01337960
- Testing
- Seated Robot Training (SRT), Treadmill Locomotor-based Training (TMR), Treadmill Only (TMO)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- US Department of Veterans Affairs
Brain Injuries
The Gut-Brain Axis During Neurorehabilitation; Prebiotic Treatment to Alter the Gut Microbiome and Neurologic Symptoms
The aim of this study is to characterize the microbiome of patients undergoing post-acute residential neurorehabilitation compared to community controls and to determine if a dietary fiber, Inulin, can create a shift in the…
- Trial name
- NCT06607523
- Testing
- Inulin
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Stroke
VNS-induced Corticospinal Plasticity
The goal of this study is to learn more about the connections between the brain, spinal cord, and muscles and how these connections can be strengthened after neurological injury.
- Trial name
- NCT04088565
- Testing
- Paired-Associative Stimulation (PAS), Vagus Nerve Stimulation (VNS)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Gait, Frontal
Influence of Short-term Vojta Therapy on the Gait in Healthy Adult Subjects.
The patterns of reflex locomotion described by Vojta contain all the basic patterns necessary for gait, which can be observed as partial patterns during normal postural ontogenesis in the first year of life.
- Trial name
- V&G (NCT04689841)
- Testing
- Vojta Therapy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- NUMEN Foundation
Ischemic Stroke, Stroke Rehabilitaion
Neurological Rehabilitation and Neuroplasticity After Ischemic Stroke
This observational study evaluates the effects of neurological rehabilitation on biological markers associated with neuroplasticity and neurotransmitter profiles in patients after ischemic stroke.
- Trial name
- NCT07899710
- Volunteers
- 60 people
- Sponsor
- Medical University of Lodz
Spinal Cord Injuries, Neuropathic Pain
Transcranial Magnetic Stimulation Therapy in Neuropathic Painful Spinal Cord Injury Patients
The aim of our study is to investigate the effect of high-frequency Repetitive Transcranial Magnetic Stimulation(rTMS) therapy applied to the dorsolateral PFC (DLPFC) area on neuropathic pain in patients with spinal cord injury.
- Conditions
- Spinal Cord Injuries, Neuropathic Pain, Neurological Diseases or Conditions
- Trial name
- NCT05645003
- Testing
- High-frequency real-time rTMS protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Afyonkarahisar Health Sciences University
Stroke, Neurological Diseases or Conditions
Development and Efficacy of a Novel, Cost-Effective Gait Training Device Utilized at Home for Stroke Survivors
This pilot, parallel-group randomized controlled trial will evaluate the feasibility, safety, usability, and preliminary efficacy of the Rise\&Walk InHome (RWH), a novel robotic gait training device designed for home use after…
- Conditions
- Stroke, Neurological Diseases or Conditions, Hemiparesis;Poststroke/CVA, Gait Disorders, Neurologic
- Trial name
- NCT07250425
- Testing
- Rise&Walk InHome by Healing Innovations
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Healing Innovations
Stroke, Spasticity as Sequela of Stroke
Radial Extracorporeal Shock Wave Therapy as an Adjunct to Botulinum Toxin Type A for Post-Stroke Lower Limb Spasticity (SOLUTION)
The goal of this pilot clinical trial is to determine whether radial extracorporeal shock wave therapy (rESWT), when used as an adjunct to ultrasound-guided botulinum toxin type A (BoNT-A) injections, can enhance the therapeutic…
- Conditions
- Stroke, Spasticity as Sequela of Stroke, Lower Limb Spasticity, Upper Motor Neuron Syndrome
- Trial name
- SOLUTION (NCT07875868)
- Testing
- Radial shock Wave therapy (3000 pulses, 5 Hz, 2.5 bar)., Ultrasound-guided abobotulinumtoxin A
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Parc de Salut Mar
Chronic Stroke
Error-enhancement for Arm Rehabilitation Post Stroke
Even in a chronic phase after stroke, most patients have difficulty moving the affected arm, resulting in limitations in simple tasks in daily living, most frequently limiting reaching task.
- Trial name
- NCT05229185
- Testing
- DeXtreme training (error-enhancement)
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acquired Brain Injury
Neurocognitive Rehabilitation Using Virtual Reality
Objective: To determine whether immersive virtual reality (VR) treatment interventions improve executive dysfunction and complex attention deficits in patients with brain injury compared with standard neurorehabilitation, and…
- Trial name
- NCT04017091
- Testing
- Virtual Reality Cognitive Training
- Volunteers
- 33 people
- Sponsor
- Baylor Research Institute
Arthroplasty, Neurologic Disorder
Implementation of a Rehabilitation Technology in Orthopedic and Neurological Rehabilitation to Increase Therapy Dosage: an Exploratory Study
Rehabilitation technology is more and more implemented in conventional therapy to increase the dosage of therapy and/or increase patient's motivation towards therapy.
- Trial name
- NCT04906681
- Testing
- i-ACT
- Volunteers
- 40 people
- Sponsor
- PXL University College