Clinical trials: Neurorehabilitation
Stroke
Impact of Gait Training on Lower Extremity Motor Function and Balance Performance in Stroke Survivors.
This randomized clinical trial evaluates and compares the effectiveness of three physiotherapy-based rehabilitation strategies in improving gait, motor function, balance, and independence in individuals recovering from stroke.
- Trial name
- NCT07066319
- Testing
- Gait Training with Proprioceptive Neuromuscular Facilitation (PNF), Gait Training with Conventional Physiotherapy, Combined PNF and Conventional Physiotherapy (without direct gait training)
- Where
- Pakistan
- Volunteers
- 99 people
- Sponsor
- University of Lahore
Parkinson Disease
Personalized Stimulation Loop for Neurorehabilitation in Parkinson: a Proof-of-principle Study
Parkinson's disease (PD) is a neurodegenerative disease that affects about 1% of the elderly population and accounts for substantial disability and health care costs.
- Trial name
- StimuLOOP_PD-S (NCT07082595)
- Testing
- TASS Intervention (Verum)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Zurich
Poststroke/CVA Hemiparesis, Paralytic Stroke
BCI Post-stroke Neurorehabilitation
The goal is to evaluate the potential of a EEG based BCI (Brain-Computer-Interface) connected to a non-invasive pneumatic glove for rehabilitation of hand-movements post-stroke.
- Conditions
- Poststroke/CVA Hemiparesis, Paralytic Stroke, Hand Flaccid Paralysis
- Trial name
- BCI-stroke (NCT02404857)
- Testing
- EEG based Brain Computer Interface
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Multiple Sclerosis
Bilateral Anodal Cerebellar tDCS for Multidomain Dysfunctions in Patients With Multiple Sclerosis
The goal of this clinical trial is to learn if brain stimulation can improve movement and daily function in people with multiple sclerosis (MS).
- Trial name
- CerebellertDCS (NCT07555379)
- Testing
- Bilateral Cerebellar Transcranial Direct Current Stimulation (ctDCS)
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- University of Sharjah
Multiple Sclerosis
Effectiveness of Exergaming in Adittion to Conventional Treatment for Physical Therapy in People with Multiple Sclerosis
The present study aims to evaluate the effectiveness of two different exergaming systems in addition to conventional treatment on physical functional capacity, balance, muscle strength, spasticity in lower limbs and quality of…
- Trial name
- NCT06196866
- Testing
- Conventional Therapy, Nintendo Ring Fit Adventure + Conventional Therapy, Nintendo Wii Fit + Conventional Therapy
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad de Córdoba
Neural Injury
Brain Connectivity Analysis
Stroke remains the leading cause of permanent disability. The neuromodulation technique of transcranial Direct Current Stimulation (tDCS) has the potential to serve as an adjuvant therapy to enhance neuronal connectivity…
- Trial name
- Neurehab (NCT06823102)
- Testing
- tDCS
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- IRCCS San Raffaele Roma
Stroke
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Stroke
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability.
- Trial name
- NCT03390192
- Testing
- Dual-mode stimulation
- Where
- South Korea
- Volunteers
- 43 people
- Sponsor
- Samsung Medical Center
Multiple Sclerosis, Rehabilitation
Eccentric Cycling in Multiple Sclerosis Rehabilitation
The project aims to optimise functional rehabilitation programmes for people with multiple sclerosis. Investigators are proposing eccentric cycling as a new exercise modality for treating these patients.
- Conditions
- Multiple Sclerosis, Rehabilitation, Neuro-Degenerative Disease, Neurorehabilitation
- Trial name
- NCT07316764
- Testing
- Eccentric training, Concentric training
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University of Liege
Stroke Acute
Feasibility of Using Immersive Virtual Functional Rehabilitation for Recovery of Upper Extremity Function in Patients With Early-stage Stroke: a Pilot Study
Feasibility of using immersive virtual functional rehabilitation for recovery of upper extremity function in patients with early-stage stroke: a pilot study
- Trial name
- IMVR Stroke (NCT07086365)
- Testing
- Immersive virtual reality
- Where
- Chile
- Volunteers
- 11 people
- Sponsor
- Clinica Alemana de Santiago
Chronic Stroke Patient, Motor Impairment
Multifocal Theta-Burst Stimulation to Enhance Upper Limb Motor Recovery After Stroke (INSPIRE)
Stroke is one of the leading causes of long-term disability worldwide. Many individuals who survive a stroke continue to experience weakness and reduced control of one arm, even months or years after the event.
- Conditions
- Chronic Stroke Patient, Motor Impairment, Neurorehabilitation, Theta Burst Stimulation
- Trial name
- INSPIRE (NCT07439367)
- Testing
- Active iTBS, Tablet-based upper limb training
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- School of Health Sciences Geneva
Multiple Sclerosis
Comprehensive Rehabilitation Programme in People With Multiple Sclerosis: The RECONNECT-MS Study
The goal of this clinical trial is to learn if a comprehensive rehabilitation programme can improve physical function, reduce fatigue, and raise quality of life in adults aged 18-65 with multiple sclerosis (MS).
- Trial name
- RECONNECT-MS (NCT07666958)
- Testing
- Individual Physiotherapy, Group Movement Awareness, Group Psychotherapy
- Where
- Czechia
- Volunteers
- 45 people
- Sponsor
- Charles University, Czech Republic
Cerebral Palsy (CP)
Pediatric Endurance and Limb Strengthening Program With and Without Electrical Muscle Stimulation Among Children With Cerebral Palsy
This randomized clinical research will assess the impact of a Pediatric Endurance and Limb Strengthening (PEDAL) program, both with and without Electrical Muscle Stimulation (EMS), on balance, gait, and mobility in children…
- Trial name
- NCT07173647
- Testing
- PEDAL Program with Electrical Muscle Stimulation, PEDAL Program without Electrical Muscle Stimulation
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- University of Lahore
Neurologic Disorder, Respiratory Insufficiency
Weaning Success in Different Weaning Strategies in Early Neurological Rehabilitation Patients - a Matched-pair Analysis
To enable weaning from mechanical ventilation, two different strategies may be distinguished: continuous weaning and discontinuous weaning.
- Trial name
- NCT05483244
- Testing
- discontinuous weaning, continuous weaning
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Stroke, Upper Extremity Paresis
BCI-FES for Upper Limb Rehabilitation in Chronic Stroke
The objective of this research is to evaluate the efficacy of an experimental therapy for motor recovery of the arm after a stroke, which includes the application of a functional electrical stimulation therapy coupled to P-300…
- Conditions
- Stroke, Upper Extremity Paresis, Neuronal Plasticity
- Trial name
- BCI-FES (NCT06409754)
- Testing
- Functional Electrical Stimulation Therapy coupled to a P-300 based Brain-Computer Interface, Conventional Physical Therapy
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Neurological Diseases or Conditions, Cardiovascular Diseases
New Technological Pathway for Gait Rehabilitation
Brief Summary The study aims to explore how the integration of visual and motor systems can be trained and enhanced to improve gait rehabilitation in patients with various neurological and cardiovascular conditions.
- Conditions
- Neurological Diseases or Conditions, Cardiovascular Diseases, Neuromuscular Disease
- Trial name
- LABODIMOTO (NCT06859229)
- Testing
- Innovative technology pathway for gait neurorehabilitation, Conventional gait rehabilitation strategy
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Stroke
Virtual Reality Training for Upper Extremity After Stroke
Background: High intensity training of challenging tasks with many repetitions is a key factor for regaining motor function after stroke.
- Trial name
- VIRTUES (NCT02079103)
- Testing
- Virtual Reality, Conventional arm training
- Where
- 5 sites in Belgium, Denmark and 1 more
- Volunteers
- 120 people
- Sponsor
- University of Bergen
Injuries, Spinal Cord
Assessment of Neurorehabilitation in Spinal Cord Injury Using Neuroimage Tools.
The sensorimotor cortex may play a role in the functional recovery after Spinal Cord Injury (SCI) through efference generated in the absence of the afference.
- Trial name
- NCT03914456
- Testing
- rehabilitation treatment
- Volunteers
- 7 people
- Sponsor
- Universidade do Vale do Paraíba
Stroke, Sleep Apnea
Telemedicine Monitoring of Sleep Apnea in Stroke
Study Objectives: Meta-analyses report a high prevalence of moderate to severe sleep apnea of more than 50% in stroke patients, with adherence rates for CPAP therapy of only 30%.
- Trial name
- HOPES (NCT02748681)
- Testing
- Auto CPAP AirSense™ 10(Resmed)
- Where
- Austria
- Volunteers
- 34 people
- Sponsor
- Neurologisches Rehabiliationszentrum Rosenhügel
Shoulder Pain, Knee Pain
Cryoneurolysis for Knee and Shoulder Pain in an Inpatient Setting
The purpose of the study is to measure the outcomes of a standard care, an ultrasound guided mini-invasive percutaneous procedure, performed on recent stroke patients on reduces pain, increases function \& quality of life The…
- Conditions
- Shoulder Pain, Knee Pain, Spasticity, Pain
- Trial name
- NCT05674604
- Testing
- Cryoneurolysis
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Vancouver Island Health Authority
Brain Injury, Tracheostomy
Efficacy of an Early Rehabilitation on Decannulation Time of Patients With Severe Acquired Brain Injury
All the patients hospitalized in the neuro-rehabilitation after a severe acquired brain injury carrying a tracheal cannula will be retrospectively analyzed.
- Conditions
- Brain Injury, Tracheostomy, Neurological Rehabilitation
- Trial name
- NCT02990871
- Testing
- early neurological rehabilitation, no-early neurological rehabilitation
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini