Clinical trials: Neurorehabilitation
Multiple Sclerosis
The Effects of Focal Vibration on Spasticity in Multiple Sclerosis Patients
This trial consists of application of little devices (named Equistasi®) generating focal vibrations to treat spasticity in neurological patients, affected by multiple sclerosis.
- Trial name
- NCT02848898
- Testing
- Equistasi
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Federico II University
Acquired Brain Injury
Neurocognitive Rehabilitation Using Virtual Reality
Objective: To determine whether immersive virtual reality (VR) treatment interventions improve executive dysfunction and complex attention deficits in patients with brain injury compared with standard neurorehabilitation, and…
- Trial name
- NCT04017091
- Testing
- Virtual Reality Cognitive Training
- Volunteers
- 33 people
- Sponsor
- Baylor Research Institute
Parkinson's Disease (PD), Physiotherapy and Rehabilitation
The Effects of Scapulohumeral Rehabilitation on Scapula Kinematics and Upper Extremity Functionality in Individuals With Parkinson's Disease
With this study, individuals diagnosed with PD in Burdur province in Turkey will be provided with a physiotherapy and rehabilitation program for the upper extremity, and it is thought that the treatment received by both groups…
- Trial name
- NCT06861933
- Testing
- Physiotherapy and rehabilitation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Multiple Sclerosis
Implementation of an Advanced Telerehabilitation Solution for People With Multiple Sclerosis
The overall purpose of the present study is to investigate the effect of an advanced telerehablitation system (TRS) in persons with multiple sclerosis on mobility.
- Trial name
- PLATINUMS (NCT07310914)
- Testing
- Telerehabilitation, Paper-based exercise
- Where
- 5 sites in Denmark, Ireland and 2 more
- Volunteers
- 94 people
- Sponsor
- Danish Multiple Sclerosis Hospitals
Stroke, Aphasia
Transcranial Alternating Current Stimulation in Post Stroke Aphasia Therapy
This study aims to investigate the efficacy of transcranial alternating current stimulation (tACS) combined with linguistic training for patients with chronic post-stroke aphasia.
- Trial name
- AfatES (NCT07510464)
- Testing
- active 75 Hz transcranial alternating current stimulation
- Where
- Poland
- Volunteers
- 11 people
- Sponsor
- QVITI S.A.
Ischemic Stroke, Depressive Symptoms
Combined tDCS and Cognitive Neurorehabilitation in Post-Stroke Depression
This study evaluates a multimodal intervention pathway for affective and cognitive symptoms after ischemic stroke. Patients undergo an initial screening of depressive symptoms, cognitive function, and quality of life.
- Trial name
- CACTUS (NCT07848919)
- Testing
- Active transcranial direct current stimulation, Cognitive neurorehabilitation using Guttmann NeuroPersonalTrainer
- Where
- Spain
- Volunteers
- 33 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
Cerebrovascular Accident
Wireless Brain-computer-interface-controlled Neurorehabilitation System for Patients With Stroke
This study integrates the wireless EEG system with an ordinary rehabilitation device (an upper limb ergometer, "arm bike") used in the Department of Physical Medicine and Rehabilitation at our hospital for a…
- Trial name
- NCT01880268
- Testing
- BCI-controlled neurorehabilitation device, Standard rehabilitation therapy
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- China Medical University Hospital
Stroke
iTMS - Implementing Transcranial Magnetic Stimulation (TMS) to Assess Cortico-spinal Tract Integrity
Reliable prediction of upper limb (UL) function can guide clinicians in choosing relevant treatment, helps to set realistic goals for rehabilitation and will contribute to personalized and effective rehabilitation.
- Trial name
- iTMS (NCT06153017)
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Follow up, Parkinson Disease
A 6-year Follow-up Study of the Effect of Neurorehabilitation Training in Patients With Parkinson's Disease
Individualization of exercise is recommended but rarely performed in patients with Parkinson's disease (PD). Unusually High Intensity and Individual Sensor Motor with Visuomotor Mobility Trainer The clinical symptoms, mobility…
- Conditions
- Follow up, Parkinson Disease, Rehabilitation
- Trial name
- NCT04559997
- Testing
- Exercise+FU, Active Comparator group Exercise
- Where
- Hungary
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital
Acquired Brain Injury, Balance Disorders
Balance Dimensions-Based Rehabilitation Program in People With Acquired Brain Injury
The purpose of this clinical trial is to find out whether a rehabilitation program based on different dimensions of balance can improve balance, mobility, walking ability, and quality of life in people with acquired brain injury.
- Trial name
- BALANCE-DCA (NCT07696663)
- Testing
- Multimodal Balance Rehabilitation Program, Conventional Physiotherapy
- Where
- Spain
- Volunteers
- 68 people
- Sponsor
- University of Castilla-La Mancha
Cerebral Palsy
Non Invasive Vagus Nerve Stimulation in Cerebral Palsy (BOOSTTVNS)
The present study aims to assess, through a randomized controlled trial (RCT), the efficacy of transcutaneous Vagus Nerve Stimulation (tVNS) in enhancing the functional changes due to an intensive motor training in children and…
- Trial name
- (BOOSTTVNS) (NCT06372028)
- Testing
- transcutaneous vagus nerve stimulation (tVNS)
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- IRCCS Eugenio Medea
Neurological Disorders, Health Adult Subjects
A Multicenter Interventional Study on the Use of a 3-Degree-of-Freedom (3DOF) Platform to Evaluate the Safety and Usability of the System and Its Impact on Balance, Proprioception, and Neurological Deficits in the Rehabilitation of Patients With Neurological Disorders.
This multicenter interventional study aims to evaluate a three-degrees-of-freedom dynamic platform (3DoF Platform) designed to support rehabilitation of balance, proprioception, and motor and cognitive functions in patients with…
- Trial name
- 3DOF (NCT07502937)
- Testing
- 3DOF balance board robotic platform group, Conventional Rehabilitation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Stroke, Sleep Apnea
Telemedicine Monitoring of Sleep Apnea in Stroke
Study Objectives: Meta-analyses report a high prevalence of moderate to severe sleep apnea of more than 50% in stroke patients, with adherence rates for CPAP therapy of only 30%.
- Trial name
- HOPES (NCT02748681)
- Testing
- Auto CPAP AirSense™ 10(Resmed)
- Where
- Austria
- Volunteers
- 34 people
- Sponsor
- Neurologisches Rehabiliationszentrum Rosenhügel
Stroke, Neurorehabilitation
Motor Imagery and Motor Execution Based BCI in Stroke
About 50% of stroke patients are unable to live independently because of residual disability. Brain-computer interface (BCI) is based on closed-loop theory, which facilitates neurological remodeling by establishing a bridge…
- Conditions
- Stroke, Neurorehabilitation, Motor Imagery, Motor Execution
- Trial name
- BCI-MIME (NCT05634616)
- Testing
- Motor imagery and motor execution based BCI
- Where
- China
- Volunteers
- 40 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Post-stroke Cognitive Impairment
Noninvasive Dual-mode Stimulation Therapy for Neurorehabilitation in Post-stroke Cognitive Impairment
Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of post-stroke cognitive impairment patients' cognitive function by altering the cortical…
- Trial name
- NCT03647319
- Testing
- High-frequency rTMS on left DLPFC+anodal tDCS on right DLPFC, High-frequency rTMS on left DLPFC+cathodal tDCS on right DLPFC
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center
Parkinson Disease, Pisa Syndrome
TRANSCRANIAL DIRECT CURRENT STIMULATION (t-DCS) AS ADD-ON TO NEUROREHABILITATION OF PISA SYNDROME IN PARKINSON DISEASE
Pisa Syndrome (PS) is a lateral trunk flexion frequently associated to Parkinson's disease (PD). The management of PS is still a challenge for the clinician, because it poorly responds to anti-parkinsonian drugs, and the…
- Trial name
- NCT04620863
- Testing
- t-DCS group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Stroke, PARKINSON DISEASE (Disorder)
Objective Longitudinal Monitoring of Postural Stability and Gait During Neurorehabilitation: Clinical Application of Instrumented Posturography and Three-Dimensional Motion Analysis
Nowadays, stroke is one of the most common leading causes of death in many countries. As the number of stroke patients is increasing, even in younger age groups, there is an increasing need to improve their rehabilitation.
- Conditions
- Stroke, PARKINSON DISEASE (Disorder), Multiple Sclerosis
- Trial name
- NCT07411664
- Testing
- Stroke posturo/3D group, Parkinson posturo/3D group, Multiple sclerosis posturo/3D group
- Where
- Hungary
- Volunteers
- 151 people
- Sponsor
- Somogy Megyei Kaposi Mór Teaching Hospital
Brain Injuries
The Gut-Brain Axis During Neurorehabilitation; Prebiotic Treatment to Alter the Gut Microbiome and Neurologic Symptoms
The aim of this study is to characterize the microbiome of patients undergoing post-acute residential neurorehabilitation compared to community controls and to determine if a dietary fiber, Inulin, can create a shift in the…
- Trial name
- NCT06607523
- Testing
- Inulin
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Memory Deficit Aquired Due to the Disease, e.g. Stroke, Neurodegeneration, Inflammatory Disease of CNS, Traumatic Brain Injury
Vestibular Stimulation in Sleep for Neurorehabilitation Patients
1. Why are we conducting this study? You are a patient of the neurorehabilitation clinic with one of the therapy focuses on memory and learning. Neuropsychological training is a standard therapeutic approach in this case.
- Trial name
- NCT07658027
- Testing
- Somnomat - rocking bed providing vestibular stimulation during sleep
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Cereneo AG
Degenerative Cervical Myelopathy
Hand Dexterity Training in Degenerative Cervical Myelopathy (DCM)
This clinical study aimed to evaluate the effectiveness of a virtual reality-based training intervention for improving hand dexterity and promoting neuroplasticity in individuals with Degenerative Cervical Myelopathy (DCM) after…
- Trial name
- NCT06754072
- Testing
- Virtual Keyboard (VK) System
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical College of Wisconsin