Clinical trials: Neuroscience
Healthy, Cancer
The Effects of a Meditation Retreat on Healthy Volunteers and Cancer Patients: an fMRI Study
The purpose of this study is to evaluate the effects of a Zen meditation retreat (Sesshin) on psychophysiological parameters in healthy volunteers (regular meditators and non-meditators) and in cancer patients and to observe…
- Trial name
- Sesshin (NCT00878735)
- Testing
- Zen meditation
- Where
- Brazil
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Visual Neurosciences
Evaluation of Visual Parameters by Visual Evoked Potentials Captured by EEG
This project will be based on an approach that has already proven itself in the field of the development of low-level visual functions such as visual acuity, vernier acuity and contrast sensitivity (Norcia \& Tyler, 1985)…
- Trial name
- NCT05675852
- Testing
- 68-electrode electroencephalography with steady state visual evoked potentials
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Neuroscience of Dreaming, Healthy
The Impact of the Opiate Antagonist Naltrexone on the Emotional Valence of Dreams
In this study, the investigators pose the question which influence the opioid circuit has on positive valent situations in dreams.
- Trial name
- NCT02792140
- Testing
- Naltrexone
- Where
- Switzerland
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Bern
Chronic Pain, Manipulation
Comparison of the Effect of Spine Grade I and II Manipulation and a PNE Video on Brainwaves: Pilot Study
The purpose of this study is to determine the effect of the use of a pain neuroscience educational video instruction on brainwave activity and compare this to the effects of a grade I \& II PA spinal oscillations of the spine…
- Conditions
- Chronic Pain, Manipulation, Psychologic
- Trial name
- NCT04908670
- Testing
- Understanding Pain in less than 5 minutes, and what to do about it! https://www.youtube.com/watch?v=C_3phB93rvI, PA manipulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Florida Gulf Coast University
Healthy Subjects
The Impact of Pain Neuroscience Education on Physical Therapy Students' Knowledge, Attitudes, Beliefs, and Behaviors Towards Pain: A Randomized Controlled Trial
This study investigates the effect of pain neuroscience education (PNE) on pain knowledge, attitudes, beliefs and behaviors among undergraduate physiotherapy students in Jordan
- Trial name
- NCT06821022
- Testing
- Pain Neuroscience Education, Red Flags Education
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Alcohol Use Disorder, Alcohol Dependence
Altering Memories That Increase Risk of Relapse in Alcohol Use Disorders
The purpose of this study is to examine the effects of rapamycin (sirolimus) versus a placebo, an inactive substance, on responses to alcohol cues in individuals with alcohol use disorder.
- Trial name
- NCT03732248
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Breast Neoplasms, Survivorship
PI-targeted PNE+MI Compared to BIOMEDICAL Education in BCS
Breast cancer is the most frequently diagnosed cancer in women worldwide. An important portion of the breast cancer survivors will face chronic pain complaints.
- Conditions
- Breast Neoplasms, Survivorship, Pain, Chronic
- Trial name
- BCS-PI (NCT04730154)
- Testing
- Pain Neuroscience Education (PNE), Motivational Interviewing (MI), Biomedically-focused education
- Where
- 4 sites in Belgium
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Carpal Tunnel Syndrome (CTS)
Pain Neuroscience Education Versus Kinesio Tape on Functional Outcomes in Patients With Carpal Tunnel Syndrome
Carpal Tunnel Syndrome (CTS) is one of the most common compressive neuropathies of the upper limb, characterized by pain, numbness, and functional impairment due to median nerve compression at the wrist.
- Trial name
- CP syndrome (NCT07539480)
- Testing
- group A: pain neuroscience education (PNE), group B: Patients receive Kinesio Taping
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Middle East University
Mindfulness, Compassion
Wisconsin Center for the Neuroscience and Psychophysiology of Meditation
The Wisconsin Center for the Neuroscience and Psychophysiology of Meditation will be a highly focused center dedicated to novel and cutting edge research on the mechanisms by which meditation works.
- Conditions
- Mindfulness, Compassion, Meditation, Mental Health
- Trial name
- NCT02157766
- Testing
- Intensive Meditation Practice, Mindfulness Based Stress Reduction, Health Enhancement Program
- Where
- 4 sites in United States
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Neurosciences
Brain Networks Involved in Inner World Control
Inner speech (the "little voice" in our heads) plays a central role in our ability to perform complex cognitive tasks such as problem solving, reading, writing, thinking, and self awareness.
- Trial name
- INNERWORLD (NCT07469631)
- Testing
- Neuropsychological evaluation, questionnaires, and training on the tasks that will be performed in the MRI., MRI visits
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pain, Pediatrics
Pain Neuroscience Education for Middle School Students
This project was designed as a single-blind, randomised controlled, prospective intervention study. The research question of the project is 'Is pain neuroscience education an effective method to improve various aspects of child…
- Conditions
- Pain, Pediatrics, Neuroscience Pain Education, Physical Activity
- Trial name
- NCT06869369
- Testing
- Turkish PNE4Kids
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Autism, Autism Spectrum Disorder
Autism Oxytocin Brain Project
The main goal of the study is to look at the effects of intranasal oxytocin on the brain in Autism Spectrum Disorder (ASD). Oxytocin is a hormone that exists naturally in the body and the brain, affecting a wide range of social…
- Trial name
- NCT03033784
- Testing
- 8 International Units (IU) of Oxytocin, 24IU of Oxytocin, 48IU of Oxytocin
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Emory University
Parkinson Disease
Motor Training in PD
The purpose of this research study is to learn more about brain activity when individuals with and without Parkinson disease (PD) move their lower limbs.
- Trial name
- NCT02457832
- Testing
- Adapted Tango Dancing, Behavioral Control (BC) Condition
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke
Role of Ipsilateral Motor Cortex in Executing Movements With Increasing Demand on Precision
It is well known that the motor area of one hemisphere of the brain (motor cortex) controls the movement of the opposite of the body.
- Trial name
- RIMC (NCT01726218)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cathrin Buetefisch
Neurological Disorders, Neuroscience
Advanced Space-time Resolved Techniques for Functional Neuroimaging at 7 Tesla MRI
In recent years, the in vivo study of the central nervous system has undergone significant advancement through the implementation of magnetic resonance imaging (MRI)-based neuroimaging techniques.
- Conditions
- Neurological Disorders, Neuroscience, Epilepsy, Brain Injuries, Focal
- Trial name
- AURORA (NCT07865546)
- Testing
- Functional neuroimaging
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Imago 7 Fondazione di Ricerca onlus
Pregnancy
Effectiveness of 12 Clips in Maternal and Neoanatal Health Through Applied Neuroscience Tools (Neuromarketing Strategy)
Objective: To evaluate the effectiveness of 12 knowledge transfer clips of maternal and neonatal health in order to generate knowledge appropriation.
- Trial name
- NCT03330860
- Testing
- Twelve clips regarding maternal and neonatal health topics, Control Clip
- Where
- Colombia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Child Development, Executive Functions (EF)
Sharing Tales That Teach: Shared Picturebook Reading for Early Childhood Emotional and Cognitive Development
Sharing Tales That Teach is a randomised study of a shared picturebook reading programme for 4- to 5-year-old children and their primary caregivers.
- Conditions
- Child Development, Executive Functions (EF), Emotion Regulation
- Trial name
- STTT (NCT07666802)
- Testing
- Emotion-Focused Shared Picturebook Reading, Standard Dialogic Picturebook Reading
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Greenwich
Rheumatic
LUMINA : Measure the Effectiveness of the Booklet Named "Comprendre Les Essais Cliniques"
Various studies have shown that many patients do not understand all the information provided by the study investigator and by the information sheet before entering a clinical research protocol.
- Trial name
- LUMINA (NCT05388344)
- Testing
- Booklet reading
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Depression, Bipolar Disorder
Neuro-computational Study of Thymic Fluctuations in Mood Disorders
Depression and bipolar disorder are frequent, debilitating conditions. Both are thought to be primarily caused by an impaired regulation of mood, which is why they are sometimes referred to as "mood disorders".
- Conditions
- Depression, Bipolar Disorder, Recurrent Depression, Mood Disorders
- Trial name
- MOODELING (NCT07033923)
- Testing
- Brain magnetic resonance imaging (MRI) with structural (anatomical) and functional sequences (optional), Computerized cognitive tests, Daily longitudinal monitoring by mobile MOODELING application
- Where
- 2 sites in France
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
Vision Disorders
Bridging Animal and Human Models of Exercise-induced Visual Rehabilitation
This study will determine whether blood biomarker changes predict sight-saving benefits of exercise.
- Trial name
- NCT02911805
- Testing
- Aerobic exercise, Balance exercise
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development