Clinical trials: Newborn, Transient
Cerebrovascular Accident, Transient Ischemic Attack
E-Selectin Nasal Spray to Prevent Stroke Recurrence
This study will test the safety and effectiveness of a protein called E-selectin, given as a nasal spray, in preventing the formation of blood clots that can cause stroke.
- Trial name
- NCT00012454
- Testing
- E-Selectin nasal spray
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Mild Cognitive Impairment (MCI), Alzheimer Disease (AD)
Biomarkers in Neurodegenerative Diseases
The general purpose of this observational study is to examine biomarkers associated with the pathology of neurodegenerative diseases to potentially develop novel therapeutic approaches.
- Conditions
- Mild Cognitive Impairment (MCI), Alzheimer Disease (AD), Dementia With Lewy Bodies (DLB), Frontotemporal Lobar Degeneration (FTLD)
- Trial name
- NCT04055532
- Testing
- Neuraceq
- Where
- United States
- Sponsor
- University of Minnesota
Hyaline Membrane Disease, Transient Tachypnea
Antenatal Corticoid Therapy for Late Preterm Babies
This study aims to determine the effectiveness of antenatal corticosteroid therapy in late preterm babies. The investigators hypothesis is corticoid accelerates fetal lung maturation even after 34 weeks and reduces risk of…
- Trial name
- ACTLPT (NCT00675246)
- Testing
- Betamethasone
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Other Preterm Infants, Transitory Neonatal Electrolyte Disturbance
Clinical Tolerance of Numeta 13%
Numeta G13% is a triple chamber bag including amino acids plus electrolytes, glucose and lipids, dedicated for parenteral nutrition in preterm newborn infants when oral/enteral nutrition is not possible, insufficient or contra…
- Conditions
- Other Preterm Infants, Transitory Neonatal Electrolyte Disturbance, Disorder of Mineral Metabolism, Failure to Thrive
- Trial name
- BAXTERULG2 (NCT01772927)
- Testing
- Parenteral Nutrition
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University of Liege
Respiratory Morbidity
Inhaled Furosemide for Transient Tachypnea of Newborn
This is a randomized double blind clinical trial in which newborns with suspected Transient tachypnea of the newborn (TTN) will receive either furosemide or normal saline by nebulizer every 6 hours for 24 hours.
- Trial name
- NCT04397991
- Testing
- Furosemide
- Where
- Lebanon
- Volunteers
- 64 people
- Sponsor
- Makassed General Hospital
Wet Lung
Role of Cord Blood Hormones and Epinephrine in the Development of Transient Tachypnea of the Newborn
In this prospective, cross-sectional study, the aim was to investigate the possible role of cord stress hormones; adrenocorticotropic hormone (ACTH), cortisol, epinephrine, sT3, sT4, and thyroid-stimulating hormone (TSH) in the…
- Trial name
- NCT01149928
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ankara University
Newborn; Newborn, Transient
Variations of High Sensitivity Troponin T in Neonates
Troponin T-us is a cardiac marker for myocardial infarction. Its use in neonates is increasing, yet normal values are still to be determined for the latest generation of tests, such as High sensitivity cardiac troponin T test.
- Trial name
- TnTc-us (NCT02880098)
- Testing
- Troponin T blood level
- Where
- France
- Volunteers
- 497 people, healthy volunteers welcome
- Sponsor
- Hôpital NOVO
Parvovirus B19 Infection
Parvovirus B19 Infection in Hereditary Hemolytic Anemias Patients
Although many studies investigated the prevalence and manifestations of HPV-B19 infection in patients with sickle cell anemia (SCA), thalassemia, and hereditary spherocytosis (HS) separately, there is limited information about…
- Trial name
- NCT04822090
- Testing
- Supportive treatment with or without red cell transfusion/intravenous immune globulin (IVIG)
- Where
- Egypt
- Volunteers
- 244 people
- Sponsor
- Sohag University
Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue, Pyoderma Gangrenosum
Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases
This study investigates the genetic architecture of Neutrophil-Mediated Inflammatory Skin Diseases. After collecting informed consent, all patients' clinical phenotype is graded at inclusion with a detailed case report form and a…
- Conditions
- Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue, Pyoderma Gangrenosum, Erosive Pustular Dermatosis of the Scalp, Sweet's Syndrome
- Trial name
- NEUTROGENE (NCT01952275)
- Testing
- Collection of biological samples
- Where
- Switzerland
- Volunteers
- 600 people
- Sponsor
- University of Zurich
Stroke, Transient Ischemic Attack
GORE® Septal Occluder Device for Patent Foramen Ovale (PFO) Closure in Stroke Patients
The primary objective is to determine if patent foramen ovale (PFO) closure with the GORE® HELEX® Septal Occluder or GORE® CARDIOFORM Septal Occluder plus antiplatelet medical management is safe and effective and reduces the risk…
- Trial name
- REDUCE (NCT00738894)
- Testing
- Septal Occluder Device, Antiplatelet Medical Therapy
- Where
- 2 sites in United States, Denmark
- Volunteers
- 664 people
- Sponsor
- W.L.Gore & Associates
Discoloration, Tooth, Malformed Tooth
Survival of Hybrid Laminate Veneers Using Two Different Tooth Preparation Techniques:Randomized Clinical Trial
The aim of this study was to evaluate the survival of laminate veneers constructed using a recent polymer-infiltrated ceramic network material following the aesthetic pre-evaluative temporary (APT) technique of tooth preparation…
- Conditions
- Discoloration, Tooth, Malformed Tooth, Diastema
- Trial name
- NCT04515069
- Testing
- traditional technique of tooth preparation, aesthetic preevaluative temporary technique for tooth preparation
- Where
- Egypt
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Cairo University
Respiratory Distress Syndrome, Newborn, Transient Tachypnea of the Newborn
Efficacy of Antenatal Steroids in Reducing Respiratory Morbidities in Late Preterm Infants
The hypothesis of the study is that administration of antenatal steroid to women at high risk of preterm birth after 34 weeks of gestation would reduce the risk of respiratory complications, specifically Respiratory Distress…
- Trial name
- NCT01206946
- Testing
- Betamethasone, Normal Saline
- Where
- 5 sites in Lebanon
- Volunteers
- 700 people
- Sponsor
- American University of Beirut Medical Center
Respiratory Distress, Transient Tachypnea of the Newborn
Effect of Supine or Prone Position After Caesarean Birth
Respiratory Distress is a frequent clinical diagnosis of babies delivered by elective Caesarean birth. There has been no study comparing the efficacy of immediately positioning a newly born infant prone vs.
- Conditions
- Respiratory Distress, Transient Tachypnea of the Newborn, Delayed Transition of the Newborn, Persistent Pulmonary Hypertension
- Trial name
- NCT01310153
- Testing
- prone positioning, Supine
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Embolic Stroke of Undetermined Source, Transient Ischemic Attack
RoBotic TCD Ultrasound BubbLe Study Compared to Transthoracic Echocardiography for Detection of Right to Left Shunt
This study is a multi-center, prospective, single-arm, non-significant risk (NSR) device study in which up to 150 evaluable subjects with suspicion of embolic stroke of undetermined source (ESUS) will be evaluated with NB-IS TCD…
- Conditions
- Embolic Stroke of Undetermined Source, Transient Ischemic Attack, Right-To-Left Atrial Shunt, Patent Foramen Ovale
- Trial name
- BUBL (NCT04604015)
- Testing
- NeuralBot Investigational System, Transthoracic Echocardiography (TTE)
- Where
- 7 sites in United States
- Volunteers
- 154 people
- Sponsor
- NeuraSignal Inc dba NovaSignal
Tourette Syndrome, Tourette's Disorder
Assessment of Children With Tic Onset in the Past 6 Months
The purpose of this research is to study why most children who have tics never develop Tourette syndrome but some do. In other words, we aim to find features that may predict whose tics will go away and whose tics will continue…
- Conditions
- Tourette Syndrome, Tourette's Disorder, Chronic Motor or Vocal Tic Disorder, Transient Tic Disorder
- Trial name
- NewTics (NCT01177774)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Washington University School of Medicine
Respiratory Distress Syndrome, Newborn
Intrapulmonary Percussive Ventilation (IPV) Versus Nasal Continuous Positive Airway Pressure Ventilation (nCPAP) in Transient Respiratory Distress of the Newborn
During caesarean section, transient respiratory distress which occurs frequently (3%) with possible complications are at present managed by non invasive nasal continuous positive airway pressure ventilation (nCPAP) associated…
- Trial name
- HFPV (NCT00556738)
- Testing
- Nasal Continuous Positive Airway Pressure ventilation, Intrapulmonary Percussive Ventilation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Bordeaux
Transient Tachypnoea of the Newborn
Trial on Treatment With Inhaled Furosemide of Preterm and Term Neonates With Transient Tachypnoea
In this study we will prospectively analyze the benefit of inhaled furosemide for preterm and term neonates with Transient Tachypnoea.
- Trial name
- NCT01407848
- Testing
- Furosemide, Saline 0,9%
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Cologne
Thermal Imaging, Neonatal Pneumonia, Tachypnea
Thermal Imaging in Neonates: A Feasibility Study in Healthy Babies and Babies With Suspected TTN
This is a study to evaluate thermal imaging as a technology to monitor the normal clearing of amniotic fluid from healthy newborns and newborns suspected of having a condition called transient tachypnea of the newborn, or TTN.
- Trial name
- NCT02570828
- Testing
- Thermal Imaging
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Respiratory Distress
Inhaled Budesonide in Transient Tachypnea of the Newborn
Background: Transient tachypnea of the newborn (TTN) caused by lung edema resulting from delayed absorption of fetal alveolar lung fluid and is a common cause of admission of late preterm and full-term infants to neonatal…
- Trial name
- NCT04758078
- Testing
- Inhaled corticosteroids
- Where
- Lebanon
- Volunteers
- 50 people
- Sponsor
- Makassed General Hospital
TTN, Respiratory Failure
the Inhaled β2-adrenergic Receptor Agonist for Transient Tachypnoea of the Newborn (the REFSAL Trial)
Clinical trial evaluating the efficacy and safety of salbutamol for the treatment of neonates with a gestational age between 32 and 42 weeks with transient tachypnoea of the newborn (TTN).
- Conditions
- TTN, Respiratory Failure, PPHN
- Trial name
- REFSAL (NCT05527704)
- Testing
- Salbutamol, 0,9% Chloride Sodium
- Where
- Poland
- Volunteers
- 608 people
- Sponsor
- Medical University of Warsaw