Clinical trials: Nicotine Vaping
Tobacco Use, Nicotine Dependence, Other Tobacco Product
A Study to Characterize Puff Topography With Use of JUUL 5% Electronic Nicotine Delivery Systems (ENDS) in Adult Smokers
A Study to Characterize Puff Topography with Use of a JUUL 5% Electronic Nicotine Delivery Systems (ENDS) in Adult Smokers
- Conditions
- Tobacco Use, Nicotine Dependence, Other Tobacco Product, Tobacco Smoking
- Trial name
- NCT03596034
- Testing
- JUUL 5%, Virginia Tobacco, ENDS product
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Juul Labs, Inc.
Tobacco Use, E-Cigarette Use
E-Cigarette Effects on Markers of Cardiovascular and Pulmonary Disease
This study is designed to enhance the understanding of the possible health effects of e-cigarette use by relating the acute and long-term use of e-cigarettes and conventional cigarettes ("products") to well-validated…
- Conditions
- Tobacco Use, E-Cigarette Use, Cardiovascular Diseases, Pulmonary Disease
- Trial name
- NCT03863509
- Testing
- Cigarettes, E-Cigarettes
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
THC, Cannabis
THC Crossover Study
This is a randomized, crossover study enrolling experienced dual cannabis-tobacco smokers (N=18) to describe the differences in THC and toxicant exposure, examining pharmacokinetic, subjective, and cardiovascular effects from…
- Conditions
- THC, Cannabis, Cannabis Smoking, Cannabis Use, Unspecified
- Trial name
- TRDRP (NCT04429568)
- Testing
- Smoked Cannabis, Vaped Cannabis, Tobacco Cigarette
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Vaping Behaviors, Message Exposure
A Text Messaging Trial to Test Vaping Health Messages Optimized to Young Adults' Vaping Status
The goal of this study is to examine if e-cigarette education messages delivered using a source and presentation tailored to one's vaping status influences young adults' vaping behaviors.
- Conditions
- Vaping Behaviors, Message Exposure, Young Adults
- Trial name
- NCT07038317
- Testing
- Intervention, Control
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Smoking Electronic Cigarettes (Vaping), With Moderate and High Dependence for Nicotine
EFFECT OF WIM HOF BREATHING EXERCISE ON VENTILATORY FUNCTIONS IN SMOKERS
Cigarette smoking is the most common form of tobacco use worldwide, but other tobacco products, such as e-cigarettes, cigars, cigarillos, roll-your-own, pipes, and various smokeless tobacco products are also damaging.
- Trial name
- NCT07153640
- Testing
- 1 ) Wim Hof Breathing Exercise, 2) Aerobic exercises
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- October 6 University
Nicotine Labeling for E-cigarettes
Survey to Test the Nicotine Concentration and Nicotine Flux Labels for E-cigarettes
Current labels for the nicotine in e-cigarette/vaping products do not sufficiently convey information to the public. The aims of this study include developing and validating two new types of labels for the nicotine in vaping…
- Trial name
- NCT07553585
- Testing
- Updated Labeling
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Yale University
Vaping, Underage
Human Factors Validation and Usability Testing of the IKE Age-Gating System
A multi-center human factors validation study to demonstrate the function of the IKE Bluetooth system on a chip (SoC) and mobile applications ability to age-gate a device, accurately identify an individuals age, race/ethnicity…
- Trial name
- NCT06952569
- Testing
- IKE System
- Where
- 4 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- IKE Tech
Tobacco Use Disorder
Comparative Acceptability of Tobacco and Menthol Flavored E-cigarettes
The study is a randomized crossover trial. Current menthol smokers will complete a session with each flavor of an electronic cigarette: menthol and tobacco. The objective of this survey is to assess for flavor preference.
- Trial name
- NCT04996940
- Testing
- E-cigarette product
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Electronic Cigarettes
Assessment of Two New Electronic Cigarettes in Cigarette Smokers
The purpose of this study is to determine differences in nicotine delivery, user behavior, subjective effects, and physiological effects, when cigarette smokers use an two new electronic cigarette devices (JUUL and IQOS) relative…
- Trial name
- NCT03435562
- Testing
- JUUL electronic cigarette, IQOS electronic cigarette, Own Brand cigarette
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Nicotine Replacement Therapy
A Study of Blood Levels of Nicotine Following an Electronic Cigarette
The purpose of this study is to assess the amount of nicotine that is absorbed into the blood stream following the use of a new Electronic Cigarette device called the CN electronic cigarette.
- Trial name
- NCT02794220
- Testing
- CN electronic cigarette 10 mg, CN electronic cigarette 15 mg, Nicorette Inhalator 15 mg
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Simbec Research
Nicotine Dependence, E-Cig Use
Research and Innovation to Stop E-cigarette/Vaping in Young Adults
The aim of this study is to test intervention components to help young adults quit vaping. A 2x2 factorial design will be used where all participants receive quitline-delivered behavioral phone counseling, and components to be…
- Trial name
- (RISE) (NCT04974580)
- Testing
- Nicotine patch, Phone Counseling, Digital Coaching
- Where
- United States
- Volunteers
- 508 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Nicotine Dependence, Other Tobacco Product
Flavors and E-cigarette Effects in Adolescent Smokers- STUDY 1
This study is to examine if inhaled doses of menthol that produce low and high cooling effects change the appeal of e-cigarettes containing low and high doses of nicotine in adolescent smokers.
- Trial name
- NCT02179034
- Testing
- Nicotine, Low Dose Menthol, High Dose Menthol
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Yale University
Perception of Vaping
Perception of Health Promotion Messages
The specific aims of this study are: 1. To compare the perceived message effectiveness (PME) of AI-generated vaping prevention materials with existing traditionally generated (typically by a health authority) prevention materials…
- Trial name
- NCT07042789
- Testing
- Material source: AI generated ads vs existing ads by health agency, source labelling conditions: control condition, AI condition, health agency condition, combined condition
- Where
- Australia
- Volunteers
- 763 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
Vaping Teens, Healthy Volunteers
Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study
The purpose of this translational bench-to-bedside study is to examine the neurobiological effects of an evidence-based technology-delivered mindfulness training (MT) program on vaping-related rsFC alterations in hippocampal…
- Trial name
- NCT06503159
- Testing
- Mindfulness-based Stress Reduction (MBSR) Program, functional magnetic resonance imaging (fMRI)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Electronic Cigarette Use
Vaporized Nicotine and Autonomic Control
E-cigarettes are marketed as an alternative to smoking for those who want to decrease the health risks of tobacco. Tobacco cigarettes increase heart rate (HR) and arterial pressure, while reducing muscle sympathetic nerve…
- Trial name
- NCT04613609
- Testing
- Electronic Cigarette containing nicotine, Electronic Cigarette without nicotine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Michigan Technological University
Tobacco Use Disorder
Electronic Cigarettes or Nicotine Inhaler for Smoking Cessation
Electronic cigarettes have shown promise but have yet to proven effective for smoking cessation. This trial will evaluate the effectiveness of electronic cigarettes in smokers who are trying to quit smoking compared with a…
- Trial name
- NCT02004171
- Testing
- electronic cigarette, nicotine inhaler
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Cardiovascular Risk Factor, Nicotine Dependence
Short-Term Cardiovascular Effects of E-Cigarettes: Influence of Device Power
This study will examine the short-term cardiovascular (CV) effects of e-cigarette device power in a randomized, crossover clinical and behavioral pharmacology study of experienced adult e-cigarette users (N=21).
- Trial name
- TCORS-1 (NCT03839745)
- Testing
- Electronic Cigarette
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
E-cigarette Use
Middle School Cluster Randomized Controlled Trial (RCT) to Evaluate E-Cigarette Prevention Program: CATCH My Breath
This is a two-arm, cluster randomized trial designed to to evaluate the effectiveness of an e-cigarette curriculum [called the CATCH My Breath (CMB) program] in delaying the onset of e-cigarette use in middle schoolers.
- Trial name
- NCT04843501
- Testing
- CATCH My Breath (CMB) program for E-cigarette prevention among adolescents, Texas Education Agency (TEA) required tobacco prevention program
- Where
- United States
- Volunteers
- 2,059 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Marijuana Dependence
Vaping THC From Electronic Cigarettes
This study aims to understand THC pharmacology and the safety of cannabis vaping, including the pharmacology and safety of co-administration of nicotine and THC.
- Trial name
- V-PAX (NCT02955329)
- Testing
- Nicotine, Cannabis, PAX Loose Leaf Vaporizer
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Nicotine Dependence
Pharmacokinetics, Subjective Effects, and Abuse Liability of Nicotine Salt-Based Vaping Products With Tobacco or Unflavored E-liquids, SALTVAPE Study
This trial studies activity of time (pharmacokinetics), subjective effects, and abuse liability of nicotine salt-based vaping products with tobacco or e-liquids.
- Trial name
- NCT04231539
- Testing
- Nicotine, Vaporizer Device, Salt-HIgh Nicotine Unflavored (Product B)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute