Clinical trials: Nitrate Supplementation
Peripheral Arterial Disease, Peripheral Artery Disease
Dietary Nitrate Supplementation and Thermoregulation
This is a double-blinded, randomized, crossover design study to assess the effects of dietary nitrate supplementation (beetroot juice) on peripheral artery disease (PAD) patients (ages 50-85) diagnosed with Fontaine stage I or II…
- Trial name
- NCT03506646
- Testing
- Beet root juice
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Nebraska
Autosomal Dominant Polycystic Kidney, Hypertension
Effect of Beetroot Juice on Reducing Hypertension in Autosomal Dominant Polycystic Kidney Disease
People with autosomal dominant polycystic kidney disease (ADPKD) develop high blood pressure and kidney disease. Previous studies have shown that a commonly occurring chemical, nitric oxide (NO), is reduced in ADPKD, and may…
- Conditions
- Autosomal Dominant Polycystic Kidney, Hypertension, Endothelial Dysfunction
- Trial name
- BEET-PKD (NCT05401409)
- Testing
- Beetroot juice, Nitrate-depleted beetroot juice
- Where
- 2 sites in Australia
- Volunteers
- 60 people
- Sponsor
- Western Sydney Local Health District
Athletic Performance
Effect of Beetroot Nitrates on Different Physical Skills in Colombian Rugby Athletes
Beetroot is a source of nitrates, which have demonstrated various positive effects in sports, with little evidence in intermittent sports such as ball sports (including rugby).
- Trial name
- NCT07106489
- Testing
- 40 meters sprint, Fitness test by bronco test, Maximal strength
- Where
- Colombia
- Volunteers
- 10 people
- Sponsor
- Universidad Nacional de Colombia
Hypoxia
The Effect of Chronic Nitrate Supplementation on Acute Mountain Sickness and Exercise Performance in Hypoxia
The study will aim to describe and evaluate the effect of chronic beetroot juice supplementation on acute mountain sickness symptoms and exercise in a hypoxic environment.
- Trial name
- NCT03101904
- Testing
- Beetroot Juice
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Bangor University
Peripheral Arterial Disease
Effect of Beetroot Juice on Coronary Blood Flow and Walking Performance in PAD
In this study the investigators will test the hypothesis that short-term consumption of inorganic nitrate (supplied in concentrated beetroot juice) enhances coronary blood flow responses, large artery hemodynamics, and leg…
- Trial name
- HeartBeet (NCT02553733)
- Testing
- Beetroot juice
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- David N. Proctor, PhD
Type 2 Diabetes
Nitrate Supplementation and Exercise Tolerance in Patients With Type 2 Diabetes
The purpose of this study is to use a randomized, double-blind, placebo controlled study design to comprehensively investigate the impact of 8-weeks of dietary nitrate supplementation on skeletal muscle blood flow, mitochondrial…
- Trial name
- NCT02804932
- Testing
- Super Beets
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Darren P Casey
Raynaud Phenomenon
Beet the Cold: The Effect of Inorganic Nitrate Supplementation in Individuals With Raynaud's Phenomenon
Individuals with Raynaud's phenomenon often experience episodes of reduced blood flow to their fingers and toes during times of stress or cold exposure, causing significant discomfort and pain.
- Trial name
- NCT03129178
- Testing
- Concentrated beetroot juice
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Portsmouth
Postmenopausal Women
Effect of Beetroot Juice on Blood Pressure Regulation in Post Menopausal Women
In this study the investigators will test the hypothesis that acute consumption of inorganic nitrate (supplied in concentrated beetroot juice) reduces artery stiffness and resting blood pressure, and lessens the rise in blood…
- Trial name
- NCT03380000
- Testing
- Beetroot juice
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Penn State University
Aging
Dietary Nitrate and Physiological Aging
The main purpose/s of this study is to examine the effects of 4 weeks of dietary nitrate supplementation on peripheral chemoreceptor sensitivity, spontaneous baroreflex sensitivity, and blood pressure responsiveness to a variety…
- Trial name
- NCT02593305
- Testing
- Super Beets
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Darren P Casey
Aging, Arterial Stiffness
Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study
This study investigates the effect of dietary inorganic nitrate supplementation on 1) large elastic artery stiffness and hemodynamics and 2) cerebrovascular function in middle-aged and older adults.
- Conditions
- Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension
- Trial name
- INCA (NCT03617302)
- Testing
- Experimental: Nitrate-containing
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gary L. Pierce, PhD
Long COVID, Cardiorespiratory Fitness
Nitrite Supplementation in Long COVID Patients
Potential benefits of a nitrate-rich juice supplement to improve skeletal muscle function and associated physical capacity will be studied in patients with Long COVID.
- Trial name
- NCT05618574
- Testing
- 140 ml per day of Beet-It nitrate beverage (James White Drinks Ltd., Ipswich, UK)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development