Clinical trials: Nitrous Oxide
Glaucoma, Sedation
Effect of Nitrous Oxide (N2O) on Intraocular Pressure in Healthy Volunteers
The purpose of this study is to learn if breathing nitrous oxide (also known as "laughing gas") changes the pressure in a person's eyes.
- Trial name
- NCT00967694
- Testing
- Nitrous oxide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Hysteroscopy
Pericervical Analgesia Versus Analesia With Nitrous Oxide (N2O) in Outpatien Operative Hysteroscopy With Miniresector
This research will have the aim of evaluating and comparing the effectiveness of two methods (analgesia with nitrous oxide and pericervical analgesia, excluding the use of paracervical block due to the increased risk of…
- Trial name
- NCT06092541
- Testing
- Intervention Group: pericervical anesthesia, Nitroux Oxide anesthesia
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ospedale degli Infermi di Biella
Labor Pain
Inhaled Nitrous Oxide and Labor Analgesia
Hypothesis: The administration of nitrous oxide for labor analgesia will decrease the labor epidural anesthesia rate by 15%. Specific Aim: To determine if nitrous oxide can be an effective alternative technique for the provision…
- Trial name
- NCT01738672
- Testing
- Inhaled nitrous oxide
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ya'aqov Abrams
Opioid-Related Disorders, Substance-Related Disorders
Cold Water Immersion Modulates Reinforcing Effects of Nitrous Oxide - 2
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000250
- Testing
- 0% N2O, 40% N2O
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Dental Anxiety
Effectiveness of Children Experiencing Nitrous Oxide/Oxygen Inhalation Sedation at an Assessment Visit Before Having Treatment.
The purpose of this study is to find out the effect of experience of dental sedation at assessment on children's anxiety before the actual treatment session.
- Trial name
- NCT06056492
- Testing
- Experience of nitrous oxide sedation at assessment
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Dr Richard Balmer
Opioid-Related Disorders, Substance-Related Disorders
Sevoflurane vs Nitrous Oxide Inhalation at Subanesthetic Concentrations - 11
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000259
- Testing
- 15 % Nitrous oxide, 0.3 % Sevoflurane, 30% Nitrous oxide
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Anxiety Disease
Comparative Evaluation of Three Anxiety Control Protocols in Third Molar Extraction
The surgery for the extraction of the third molars is a procedure in Dentistry that generates a large picture of anxiety in the patient. One of the ways to try to soften this picture, are the professionals to use sedation.
- Trial name
- NCT03165500
- Testing
- Diazepam, Midazolam, Nitrous Oxide + Oxygen Gas
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Nitrous Oxide
Colonoscopy Using Nitrous Oxide- A Pilot Study in the USA
Colon cancer is the second most common cancer in men and the third most common cancer in women worldwide. The clinical objectives of administering sedation for GI endoscopy are to relieve patient anxiety and discomfort and to…
- Trial name
- NCT04305158
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Opioid-Related Disorders, Substance-Related Disorders
Effects of Subanesthetic Concentrations of Nitrous Oxide - 1
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000249
- Testing
- 20% N2O, 30% N2O, 40% N2O
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Labor Pain
Virtual Reality Compared to Nitrous Oxide for Labor Analgesia
The purpose of this study is to determine if non-invasive distracting devices (Virtual Reality headsets) are non-inferior to conventional therapy (nitrous oxide) for addressing maternal needs during labor who desire non-epidural…
- Trial name
- NCT04749043
- Testing
- Oculus Quest 2 Virtual Reality Device, Nitrous oxide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brendan Carvalho
Anesthesia, Pain
Nitrous Oxide Neuroimaging
The purpose of this study is to determine the effects of acute pain on long-term memory and conditioned physiologic responses in the presence and absence of low dose nitrous oxide.
- Conditions
- Anesthesia, Pain, Amnesia
- Trial name
- NONI (NCT06702631)
- Testing
- Nitrous oxide, Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Keith M Vogt
Opioid-Related Disorders, Substance-Related Disorders
Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000260
- Testing
- Nitrous oxide
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Anesthesia
Physiological Effects of Nitrous Oxide on Anaesthesia
Nitrous oxide is the oldest anaesthetic agent still in routine use today. Despite huge changes in the pharmacology of volatile anaesthetic agents and intravenous anaesthetics, the unique properties of nitrous oxide have…
- Trial name
- NCT01092923
- Testing
- sevoflurane on air/O2, sevoflurane in N2O/O2
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Austin Health
Pregnancy
Nitrous Oxide and Neuraxial Labor Analgesia Use on Maternal Fetal Outcomes
The purpose of this study is to evaluate maternal and neonatal outcomes in parturients who used nitrous oxide and neuraxial labor analgesia during labor.
- Trial name
- NOLA (NCT04813874)
- Testing
- Nitrous Oxide, Neuraxial analgesia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Opioid-Related Disorders, Substance-Related Disorders
Reinforcing Effects of Brief Exposures to Nitrous Oxide - 8
The purpose of this study is to conduct experiments to examine subjective and reinforcing effects of nitrous oxide. Mood altering and psychomotor effects will be tested on non-drug abusers and preference procedures will be used…
- Trial name
- NCT00000256
- Testing
- 20% N2O, 40% N2O, 60% N2O
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Anesthesia
Mixture Nitrous Oxide - Oxygen 50-50% in Transrectal Prostate Biopsy Guided by Ultrasound
Introduction: Transrectal ultrasound-guided prostate biopsy (TUPB) is the gold standard diagnostic tool for prostate cancer and, though may be well tolerated for some patients, about 65 to 90% of then still complain of…
- Trial name
- NCT02899182
- Testing
- Nitrous Oxide NO, O2
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Clinical Anxiety, Clinical Cooperation
Comparison of Effect of Nitrous Oxide-Oxygen Conscious Sedation and Cognitive-behavioral Therapy on Children's Anxiety in Dentistry
Visiting anxious and fearful children is an inevitable prospect of the daily work of every dentist who treats pediatric patients.
- Trial name
- NCT02024594
- Testing
- Nitrous Oxide-Oxygen conscious sedation, cognitive-behavioral therapy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Acute Pain, Anxiety
The 50:50 Nitrous Oxide vs 2% Lidocaine Challenge
The main goal of the project is to assess pain levels and patient comfort during the administration of a 50:50 Nitrous Oxide/Oxygen gas mixture, in comparison to the same parameters under the standard method used at our…
- Conditions
- Acute Pain, Anxiety, Central Venous Catheter
- Trial name
- NCT07618676
- Testing
- Nitrous Oxide-Oxygen, Lidocaine 2% Injectable Solution
- Where
- Serbia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Institute for Oncology and Radiology of Serbia
Behavior, Child
Oral Sedation With and Without Nitrous Oxide
Aims: The objective of the current study was to evaluate the effectiveness of oral midazolam-hydroxyzine with/without nitrous oxide. Design: This was a randomized split mouth, cross over and triple-blinded clinical study.
- Trial name
- NCT03728894
- Testing
- Midazolam-hydroxyzine with 100% O2, Midazolam-hydroxyzine with 50% N2O/O2
- Where
- Syria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Latakia University
Pain Alleviation, Dilatation and Evacuation
Use of Nitrous Oxide for Pain Alleviation in Women Undergoing Osmotic Dilator Insertion for Dilatation and Evacuation
A randomised control study aiming to examine whether inhaled N2O/O2 during cervical preparation for second trimester dilatation and evacuation with osmotic dilators (laminaria) alleviates pain and is superior to placebo.
- Conditions
- Pain Alleviation, Dilatation and Evacuation, Laminaria Placement, Nitrous Oxide
- Trial name
- NCT05579288
- Testing
- Nitrous oxide (N2O/O2), Oxygen (O2)
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center