Clinical trials: Non-Suicidal Self-Injury
Nonsuicidal Self-injury, Suicidal Ideation
Addressing Nonsuicidal Self-injury in Schools
The aim of this study is to study the effectiveness of a whole-school approach that addresses non-suicidal self-injury and targets adolescents, parents and teachers.
- Conditions
- Nonsuicidal Self-injury, Suicidal Ideation, Stigmatization, Help-Seeking Behavior
- Trial name
- NCT05935345
- Testing
- Addressing NSSI in schools, Control condition
- Where
- Sweden
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Region Östergötland
Non Suicidal Self Injury, Cognitive Behavior Therapy
Evidence-based Digital CBT for Nonsuicidal Self-Injury
To evaluate if evidence-based digital cognitive behaviour therapy for adolescents is an efficacious treatment when delivered as an adjunctive treatment to treatment as usual, compared to a control group consisting of treatment as…
- Trial name
- NCT07337473
- Testing
- Evidence-based digital cognitive behaviour therapy, Health Education
- Volunteers
- 100 people
- Sponsor
- Peking University Sixth Hospital
Nonsuicidal Self Injury, Risk-Taking
Social Feedback and Dysfunctional Risk Taking in NSSI Adolescents
Nonsuicidal self-injury (NSSI) is defined as direct, intentional physical injury without suicidal intention. Problematic interpersonal relationships and decision-making have been demonstrated to play crucial roles in this…
- Trial name
- NCT05981677
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Nonsuicidal Self Injury, Emotion Regulation
Neuro- and Biofeedback in Nonsuicidal Self-injury
Nonsuicidal self-injury (NSSI) is defined as the direct, deliberate destruction of one's own body tissue without suicidal intent, typically including behaviors such as cutting, burning, or hitting oneself.
- Trial name
- NCT05656001
- Testing
- Real-time functional magnetic resonance imaging Neurofeedback and Real-time Biofeedback
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Östergötland
Transcranial Direct Current Stimulation, Non Suicidal Self Injury
Intervention Effect of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Non-suicidal Self-injury (NSSI)
To investigate the intervention effect of high-definition transcranial Direct Current Stimulation (HD-tDCS) on patients with Non-suicidal Self-injury (NSSI) and its underlying neural mechanism by magnetic resonance imaging (MRI).
- Trial name
- NCT06148363
- Testing
- High-Definition transcranial Direct Current Stimulation (HD-tDCS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Depression
iTBS for Adolescent Depression: An Open Label Study Evaluating Safety and Efficacy of Treatment
This is an open label, pilot, feasibility study evaluating effects of Intermittent Theta Burst Transcranial Magnetic Stimulation (iTBS) on 5 eligible adolescents for the treatment of depression.
- Trial name
- NCT04485455
- Testing
- iTBS Device/Motor Threshold Coil, iTBS Device/Treatment Coil
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill
Self-Harm, Self-harm Behavior
Self-harm and the Prison Environment Mixed Methods Study
Self-harming behaviour is a major problem in UK prisons: the number of self-harm incidents has more than doubled over the past decade. People who self-harm in prison are at greater risk of subsequent death by suicide.
- Conditions
- Self-Harm, Self-harm Behavior, Self-Harm, Deliberate
- Trial name
- SHAPE (NCT06895668)
- Testing
- None (cohort study)
- Volunteers
- 458 people, healthy volunteers welcome
- Sponsor
- King's College London
Borderline Personality Disorder, Self-harm
Effects of Psychiatric Admissions on Self-harm and Suicide in People With Borderline Personality Disorder
The current study aims to evaluate the impact of long (>5 days) and/or compulsory psychiatric inpatient care on subsequent healthcare utilization for self-harm and suicide in people with borderline personality disorder, a…
- Conditions
- Borderline Personality Disorder, Self-harm, Non-suicidal Self-injury, Suicide
- Trial name
- NCT06424509
- Testing
- High degree of long (>5 days) and/or compulsory psychiatric inpatient care
- Where
- Sweden
- Volunteers
- 390 people
- Sponsor
- Lund University
Self-Injurious Behavior, Mental Retardation
Self-Injury: Diagnosis and Treatment
Self-injurious behavior is behavior in which a person hurts or harms himself. This behavior sometimes occurs in people with mental retardation or autism.
- Trial name
- NCT00065936
- Testing
- Naltrexone hydrochloride, Transcutaneous sensory nerve stimulation
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Nonsuicidal Self-injury, Mindfulness
Formal Versus Informal Mindfulness Among University Students With and Without Recent Nonsuicidal Self-injury
The present study will use a randomized controlled design to investigate group differences between students with and without a history of nonsuicidal self-injury (NSSI) in response to a single-session mindfulness induction across…
- Conditions
- Nonsuicidal Self-injury, Mindfulness, Stress, Well-Being
- Trial name
- NCT05608304
- Testing
- Formal mindfulness induction, Informal mindfulness induction, Active control task
- Where
- Canada
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- McGill University
Nonsuicidal Self-injury
Interrupting Self-Harm Study
My study will employ a convergent mixed methods two-arm parallel randomized controlled design. The qualitative strand will primarily rely on semi-structured interview procedures to answer the following questions: (1) How do…
- Trial name
- NCT03550521
- Testing
- Mindfulness
- Where
- United States
- Sponsor
- University of Utah
Psychiatric Disorder
Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in Adolescents
Non-suicidal self-injury (NSSI) are acts defined by the DSM-5 (Diagnostic and Statistical Manual of Mental Disorders 5) as intentional and deliberate, occurring outside a psychotic state and directly causing moderate injury.
- Trial name
- NEUROMUTE (NCT06433583)
- Testing
- transcutaneous auricular vagal nerve stimulation
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Transcranial Alternating Current Stimulation, Non-suicidal Self-injury
Intervention Effect of High-Definition Transcranial Alternating Current Stimulation (HD-tACS) on Non-suicidal Self-injury (NSSI)
To investigate the intervention effect of high-definition transcranial alternating current stimulation (HD-tACS) on patients with Non-suicidal Self-injury (NSSI) and its underlying neural mechanism by magnetic resonance imaging…
- Trial name
- NCT06127056
- Testing
- High-Definition Transcranial Alternating Current Stimulation (HD-tACS)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
NSSI
Effects of Repetitive Transcrannial Magnetic Stimulation on Non-Suicidal Self-Injury
Non-suicidal self-injury (NSSI) refers to a series of direct and consequently repeated injuries to one's body without suicidal intent. At present, it has become an important issue of mental disorders.
- Trial name
- NCT06540300
- Testing
- rTMS stimulation of left M1
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing Medical University
Non-suicidal Self-injury (NSSI), Adolescent
Clinical and Psychosocial Characteristics of Adolescent Patients With Non-Suicidal Self-Injury
The overall objective of this study is to explore the social and clinical psychological characteristics of adolescents with depression accompanied or not accompanied by non-suicidal self-harm. This is an observational study.
- Conditions
- Non-suicidal Self-injury (NSSI), Adolescent, Depression
- Trial name
- NCT06885749
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Major Depressive Disorder, Bipolar Depression
aiTBS for Relieving NSSI in Depressive Patients
Repetitive transcranial magnetic stimulation (rTMS) has been successfully used to help patients with treatment resistant depression. However, its role in alleviating self injuries without suicidal ideation remained uncertain.
- Trial name
- NCT05384405
- Testing
- Active iTBS
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Central South University
Problem Behavior, Aggression
Basic and Applied Research on Extinction Bursts
Although highly effective, treatments like FCT include extinction, which can have adverse side effects. The extinction burst, an increase in the frequency or intensity of destructive behavior at the start of treatment, is the…
- Conditions
- Problem Behavior, Aggression, Self Injury
- Trial name
- NCT05925101
- Testing
- Extinction-only condition, Rate-drop condition, Rate-hold condition
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Non-suicidal Self-injury (NSSI)
Efficacy of Triple-daily 15mA tACS on Adolescent NSSI
This study aims to evaluate the clinical effectiveness of triple-daily 15 mA tACS stimulation in adolescents with Nonsuicidal Self-Injury (NSSI) by comparing the outcomes of active versus sham tACS interventions.
- Trial name
- NCT06919432
- Testing
- Active-tACS (Nexalin Technology, Inc., Houston, TX, USA)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Mental Health Center
Tuberous Sclerosis Complex, Self-injury
Rapalogues for Autism Phenotype in TSC: A Feasibility Study
The purpose of this study is to assess the feasibility and safety of administering rapalogues, sirolimus or everolimus, in participants with Tuberous Sclerosis Complex (TSC) and self-injury and to measure cognitive and behavioral…
- Conditions
- Tuberous Sclerosis Complex, Self-injury, Autism
- Trial name
- RAPT (NCT01929642)
- Testing
- Sirolimus, Everolimus
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.