Clinical trials: Non-cardiac Chest Pain
Stable Angina Pectoris, Unstable Angina Pectoris
Non-invasive Diagnosis of Coronary Artery Stenoses by Doppler Echocardiography
Non-invasive evaluation of patients with stable angina and unstable coronary syndromes with transthoracic Doppler echocardiography to evaluate presence of significant coronary stenoses.
- Conditions
- Stable Angina Pectoris, Unstable Angina Pectoris, Acute Myocardial Infarction
- Trial name
- NCT00281346
- Testing
- Doppler echocardiography
- Where
- Norway
- Volunteers
- 110 people
- Sponsor
- Norwegian University of Science and Technology
Acute Coronary Syndrome, Coronary Atherosclerosis
Routine Versus Selective Use of FFR to Guide PCI
Fractional flow reserve (FFR) is a test that can be performed at the time of heart catheterization. It measures the change in pressure across a narrowing in the heart artery during high flow situation, and provides reliable…
- Conditions
- Acute Coronary Syndrome, Coronary Atherosclerosis, Angina, Unstable
- Trial name
- FFR-SELECT (NCT02000661)
- Testing
- Fractional Flow Reserve (FFR)
- Where
- 4 sites in Canada
- Volunteers
- 261 people
- Sponsor
- Cardiology Research UBC
Coronary Artery Disease, Heart Attack
Registry of Non-primary Angioplasty at Hospitals Without Surgery On-site
This is a simple registry of patients undergoing PCI at hospitals without surgery on-site who were participants in the CPORT-E project.
- Conditions
- Coronary Artery Disease, Heart Attack, Angina
- Trial name
- CPORT (NCT02137980)
- Where
- 37 sites in United States
- Volunteers
- 31,390 people
- Sponsor
- Johns Hopkins University
Acute Coronary Syndrome, Depression
MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms
Brief Summary: The aim of this study is to explore the initial feasibility and acceptability of (a) Mindfulness-Based Cognitive Therapy (MBCT) adapted for ACS patients; (b) the group videoconferencing delivery medium; and (c)…
- Conditions
- Acute Coronary Syndrome, Depression, Myocardial Infarction, Unstable Angina
- Trial name
- NCT04231097
- Testing
- MBCT intervention for ACS patients
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Chronic Stable Angina, Unstable Angina
The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Study
The association between alcohol consumption and cardiovascular disease (CVD) has mostly been examined using broad endpoints or cause-specific mortality.
- Conditions
- Chronic Stable Angina, Unstable Angina, Coronary Heart Disease Not Otherwise Specified, Acute Myocardial Infarction
- Trial name
- NCT01864031
- Where
- United Kingdom
- Volunteers
- 2,240,000 people
- Sponsor
- University College, London
Coronary Syndrome
Assessment of New Biomarkers in the Management and Triage of Patients With Chest Pain and Suspicion of Non ST Elevation Acute Coronary Syndrome.
To assess diagnostic and prognostic value of new biomarkers in patients admitted for suspicion of non ST elevation acute coronary syndrome (NSTE ACS).
- Trial name
- NCT00769574
- Testing
- Biological analysis of biomarkers
- Where
- France
- Volunteers
- 143 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
ACS, NSTEMI - Non-ST Segment Elevation MI
Prehospital Triage of Patients With Suspected Non-ST-segment Elevation Acute Coronary Syndrome: the TRIAGE-ACS Study
With the Emergency Medical Services (EMS), no prehospital risk stratification and triage is performed for patients suspected of having an Non-ST-segment elevation Acute Coronary Syndrome (NSTE-ACS).
- Conditions
- ACS, NSTEMI - Non-ST Segment Elevation MI, Unstable Angina
- Trial name
- NCT05243485
- Testing
- PreHEART
- Where
- Netherlands
- Volunteers
- 1,071 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Unstable Angina
MMP Polymorphisms and Acute Coronary Syndromes
Some Matrix Metalloproteases, proteases degrading the extracellular matrix, play a relevant role in structure and stability of atherosclerotic plaques.
- Trial name
- NCT00484406
- Where
- 2 sites in Italy
- Sponsor
- University of Trieste
Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Acute Coronary Syndromes
AI-Assisted Coronary Syndrome Subtyping From Admission History of Present Illness: A Clinician Reader Study
This study will evaluate whether an OCR-LLM-based clinical decision support framework improves clinicians' accuracy in classifying coronary syndrome subtypes from admission history of present illness.
- Conditions
- Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Acute Coronary Syndromes, ST-segment Elevation Myocardial Infarction (STEMI), Non-ST-Segment Elevation Myocardial Infarction (NSTEMI)
- Trial name
- OCR-LLM-CHD (NCT07449429)
- Testing
- OCR-Prompt-LLM Information Extraction and Classification Workflow (OCR-Prompt-LLM), Manual Clinical Data Review
- Where
- China
- Volunteers
- 10 people
- Sponsor
- China National Center for Cardiovascular Diseases
Acute Coronary Syndrome, Troponin
Pragmatic Randomised Trial of the ESC 0/1 Versus 0/3 Hour Troponin Pathway
The primary objective of this study is to assess the feasibility and impact of implementing the ESC 0-1 hour high sensitive troponin pathway in clinical practice and with specific reference to the 0-3 hour pathway currently in…
- Conditions
- Acute Coronary Syndrome, Troponin, Chest Pain, Point-of-care Systems
- Trial name
- MACROS2 (NCT05322395)
- Testing
- ESC 0/1 hour troponin pathway
- Where
- United Kingdom
- Volunteers
- 3,536 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Acute Coronary Syndromes, Chest Pain
AI-ECG Detection of Occlusion Myocardial Infarction at Emergency Department Triage (TRIACS)
Chest pain is among the most common reasons people attend an emergency department, and the electrocardiogram (ECG) recorded at triage is the first test used to decide who needs urgent treatment for a blocked coronary artery.
- Conditions
- Acute Coronary Syndromes, Chest Pain, Myocardial Infarction (MI), NSTEMI - Non-ST Segment Elevation MI
- Trial name
- TRIACS-MB (NCT07882849)
- Where
- Slovenia
- Volunteers
- 1,000 people
- Sponsor
- University Medical Centre Maribor
ASCVD, NSTEMI
Telehealth Group Counseling and Preventive Care for Women
The purpose of this study is to utilize an innovative healthcare delivery strategy via telehealth group counseling sessions to improve engagement, adherence, and ultimately outcomes in female patients with atherosclerotic…
- Conditions
- ASCVD, NSTEMI, STEMI, Coronary Artery Disease
- Trial name
- NCT06404515
- Testing
- Telehealth Group Counseling
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Weill Medical College of Cornell University
Non-cardiac Chest Pain, Cardiac Anxiety
Internet-delivered CBT for Patients With NCCP
Non-cardiac chest pain (NCCP) is common and has substantial impact on patients' psychological wellbeing, quality of life and healthcare use.
- Trial name
- IKSIT (NCT03336112)
- Testing
- Internet-delivered cognitive behavioral therapy (I-CBT), Information program
- Where
- Sweden
- Volunteers
- 109 people
- Sponsor
- Linkoeping University
Myocardial Ischemia
MCG for Non-Obstructive Myocardial Ischemia
The aim of this prospective study is to identify Non-Obstructive Myocardial Ischemia of patients who have acute chest pain using Magnetocardiography.
- Trial name
- NCT07657546
- Testing
- Magnetocardiography
- Where
- China
- Volunteers
- 3,786 people
- Sponsor
- Qilu Hospital of Shandong University
Angina Patients With Non-obstructive Coronary Artery Disease, Coronary Microvascular Disease
Study Targeting Myocardial Perfusion and Symptom Relief in Women With SGLT2 Inhibitors (STRONG)
The goal of this clinical trial is to that Sodium-glucose cotransporter 2 inhibitors treatment will improve Coronary Microvascular Disease with anginal symptoms associated with non-obstructive coronary disease in women.
- Conditions
- Angina Patients With Non-obstructive Coronary Artery Disease, Coronary Microvascular Disease, Coronary Microvascular Dysfunction (CMD)
- Trial name
- STRONG (NCT06600178)
- Testing
- Brenzavvy (bexagliflozin), 20 mg Oral Tablet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Virginia
Stable Angina, Angina, Unstable
DEDICA (Dose of HEparin During Coronary Angioplasty) Trial
International guidelines support the use of a full-dose heparin (anticoagulants) during coronary intervention. However, a lower dose of heparin may be adequate, thanks to advances in angioplasty techniques and the widespread use…
- Conditions
- Stable Angina, Angina, Unstable, Non-ST Elevation (NSTEMI) Myocardial Infarction
- Trial name
- DEDICA (NCT01694459)
- Testing
- Low-dose heparin, Standard dose heparin
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- San Filippo Neri General Hospital
Coronary Artery Disease
Coronary CT Angiography as the Primary Initial Method of Evaluating Patients With Subacute Chest Pain (CT PRIME)
This study is designed to evaluate a new approach to the diagnosis of chronic or sub-acute chest pain patients in the out-patient setting.
- Trial name
- CTPRIME (NCT00584337)
- Where
- United States
- Sponsor
- Corewell Health East
Stable Angina, Unstable Angina
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial
We had little experience in coronary intervention with recently introduced newer drug-eluting stent (DES) platforms, despite great anticipation, and optimal duration of dual antiplatelet therapy (DAPT) for these stent systems…
- Conditions
- Stable Angina, Unstable Angina, Non-ST Segment Elevation Myocardial Infarction
- Trial name
- HOST-IDEA (NCT02601157)
- Testing
- 3-months DAPT, 1-year DAPT
- Where
- 12 sites in South Korea
- Volunteers
- 2,173 people
- Sponsor
- Seoul National University Hospital
Acute Coronary Syndrome
Vaccination Against Influenza to Prevent Cardiovascular Events After Acute Coronary Syndromes
Cardiovascular disease has a great burden in the context of public health, as well as the low pharmacological adherence of patients who have chronic non-transmissible diseases.
- Trial name
- VIP-ACS (NCT04001504)
- Testing
- Double Dose Quadrivalent Influenza Vaccine, Standard Dose Quadrivalent Influenza Vaccine
- Where
- 22 sites in Brazil
- Volunteers
- 1,801 people
- Sponsor
- Hospital Israelita Albert Einstein
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Austria Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01667016
- Where
- 8 sites in Austria
- Volunteers
- 305 people
- Sponsor
- Biotronik Vertriebs-GmbH