Clinical trials: Non-obstructive Coronary Artery Disease
Arterial Obstructive Diseases, Coronary Disease
Safety of SCH 530348 in Subjects Undergoing Non-Emergent Percutaneous Coronary Intervention (Study P03573)
The object of the study is to determine whether different doses of SCH 530348, when added to standard medical care in persons undergoing percutaneous coronary intervention, will increase the risk of bleeding.
- Trial name
- NCT00132912
- Testing
- SCH 530348
- Volunteers
- 1,030 people
- Sponsor
- Merck Sharp & Dohme LLC
Coronary Artery Disease, Non-Obstructive Coronary Atherosclerosis
VIsualization of Coronary Artery Disease for Modification of RISK Factors
The VICAD-RISK study assesses if visualization of coronary CT angiography (CTA) images in participants with non-obstructive coronary artery disease will improve LDL lowering, reduce reporting of side effects by cholesterol…
- Trial name
- VICAD-RISK (NCT06413641)
- Testing
- Follow up at general practice, Consultation, Visualization of CTA images
- Where
- 5 sites in Denmark
- Volunteers
- 273 people
- Sponsor
- Aarhus University Hospital
Covid19, SARS-CoV-2 Infection
Analysis of Chronic Non-infectious Diseases Dynamics After COVID-19 Infection in Adult Patients
Non-commercial depersonalized multi-centered registry study on analysis of chronic non-infectious diseases dynamics after SARS-CoV-2 infection in adults.
- Conditions
- Covid19, SARS-CoV-2 Infection, Pneumonia, Copd
- Trial name
- ACTIV (NCT04492384)
- Testing
- non-interventional
- Where
- Russia
- Volunteers
- 6,396 people
- Sponsor
- Eurasian Association of Therapists
Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease)
Diagnostic and Clinical Management of Non-Obstructive Myocardial Ischemia in Patients With Long Covid-19 Syndrome and New Onset Chest Pain
Long Covid-19 INOCA is an investigator-initiated, prospective, randomized, sham-controlled, single center study. Its objective is to investigate the benefits of tailored medical therapy according to the results of the coronary…
- Conditions
- Angina (Stable), INOCA (Ischemia With Non Obstructive Coronary Artery Disease), Long COVID-19 Syndrome
- Trial name
- NCT07559994
- Testing
- Coronary functional test
- Where
- Spain
- Volunteers
- 108 people
- Sponsor
- Fundacion Investigacion Interhospitalaria Cardiovascular
Microvascular Angina, Angina, Stable
iCorMicA - Stratified Medicine in Angina
The iCorMicA study is a multicentre, prospective, randomised, double-blind, sham-controlled, parallel-group, end-point trial and registry.
- Conditions
- Microvascular Angina, Angina, Stable, Ischemia With No Obstructive Coronary Arteries (INOCA), Coronary Microvascular Dysfunction (CMD)
- Trial name
- iCorMicA (NCT04674449)
- Testing
- Disclosure of IDP results, IDP performed but results not disclosed
- Where
- 39 sites in Ireland, Netherlands and 2 more
- Volunteers
- 1,500 people
- Sponsor
- NHS Greater Glasgow and Clyde
Ischemia With no Obstructive Coronary Artery Disease
BIOmarkers and PLAtelet Function Assessment in Myocardial Ischemia and Non Obstructive Coronary Arteries Study
Ischemia with non-obstructive coronary artery disease (INOCA) identifies a significant proportion of patients presenting with signs and symptoms of myocardial ischemia with normal or near-normal coronary arteries at angiography.
- Trial name
- BIOplatINO (NCT05714241)
- Testing
- Data extraction, Blood sampling, Clinical Follow-up
- Where
- 2 sites in Italy, Spain
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coronary Microvascular Dysfunction, Coronary Microvascular Disease
Insulin Resistance and Coronary Microvascular Dysfunction in Patients With Myocardial Ischemia and Non-obstructive Coronary Artery Disease
The goal of this prospective study is to assess the correlation between coronary microvascular disfunction and insulin resistance in patients with INOCA.
- Conditions
- Coronary Microvascular Dysfunction, Coronary Microvascular Disease, Insulin Resistance
- Trial name
- IRIN (NCT06597851)
- Testing
- Thermodilution based assessment of coronary microcirculation, Hyperinsulinemic-euglycemic Clamp test
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Non-Obstructive Coronary Artery Disease
Non Obstructive Versus Obstructive Coronary Artery Disease
The goal of this observational study is to study the non obstructive type of ischemic heart disease by identifying unique clinical features , frequency and age group .in patient admitted in coronary care unit , suffered from…
- Trial name
- NCT05738876
- Testing
- CORONARY ANGIOGRAPHY
- Where
- Iraq
- Volunteers
- 167 people
- Sponsor
- Arab Board of Health Specializations, Iraq
Myocardial Infarction
Mechanisms of Myocardial Infarction in Women With Non Obstructive Coronary Artery Disease
The objective of our work to determine the mechanisms of myocardial infarction in women without obstructive coronary artery disease.
- Trial name
- NCT01953029
- Testing
- cardiac imajing
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Chronic Obstructive Pulmonary Disease (COPD), Acute Coronary Syndrome
Feasibility Study of a Digital Interactive Life-style Platform for Individuals After Rehabilitation
The goal of this clinical trial is to evaluate the feasibility and usability of a digital lifestyle platform designed to support patients after discharge from inpatient rehabilitation.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Acute Coronary Syndrome, Fragility Fracture, Minor Stroke
- Trial name
- Feas Platf (NCT07597031)
- Testing
- Digital Lifestyle Platform, Usual Care (Standard Post-Rehabilitation Care)
- Where
- 2 sites in Switzerland
- Volunteers
- 240 people
- Sponsor
- Matthias Wilhelm, MD
Coronary Atherosclerosis, Myocardial Ischemia
Myocardial Ischemia in Non-obstructive Coronary Artery Disease
The aim of the study is to assess presence of myocardial ischemia by contrast stress echocardiography in patients with symptomatic non-obstructive coronary artery disease (CAD) by CT-coronary angiography, and the clinical…
- Trial name
- MicroCAD (NCT01853527)
- Where
- Norway
- Volunteers
- 132 people
- Sponsor
- University of Bergen
Spontaneous Coronary Artery Dissection, SCAD
Canadian SCAD Study
Natural history multicenter, prospective, observational registry with 10-year follow-up
- Conditions
- Spontaneous Coronary Artery Dissection, SCAD, Fibromuscular Dysplasia
- Trial name
- NCT04906356
- Testing
- Genetic sub-study
- Where
- Canada
- Volunteers
- 3,000 people
- Sponsor
- Cardiology Research UBC
Microvascular Angina
Microvascular Assessment of Ranolazine in Non-Obstructive Atherosclerosis (MARINA)
The purpose of this study is to look at the effects of the drug Ranolazine compared to Placebo on symptoms of chest pain or chest tightness (known as angina), exercise endurance and ability, and changes in blood flow to the very…
- Trial name
- MARINA (NCT02147067)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Emory University
Myocardial Infarction With Non-obstructive Coronary Arteries, Cardiac Shock Wave Therapy
Cardiac Shock Wave Therapy for the Treatment of Myocardial Infarction With Non-obstructive Coronary Arteries
Myocardial infarction with non-obstructive coronary arteries (MINOCA) accounts for 15% of all myocardial infarctions and its mortality rate approaches that of large vessel myocardial infarction, but there are currently no…
- Trial name
- NCT05935436
- Testing
- Cardiac Shock Wave Therapy
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Ya-Wei Xu
Acute Coronary Syndrome, Myocardial Infarction
Myocardial Infarction With Non-obstructive Coronary Arteries in Turkish Population
The objective of this study is to analyze the Demographics, Clinical Profiles, Management, in-Hospital and Long-Term Outcomes of Patients with Acute Coronary Syndrome Syndrome And Myocardial Infarction with Non-obstructive…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Atrial Fibrillation, Diabetes Mellitus
- Trial name
- MINOCA-TR (NCT03364387)
- Where
- Turkey (Türkiye)
- Volunteers
- 16,026 people
- Sponsor
- Cardiovascular Academy Society, Turkey
Myocardial Ischemia, Non-Obstructive Coronary Atherosclerosis
Myocardial Ischemia Without Obstructive Coronary Stenoses
Coronary-related myocardial ischemia can result from obstructive epicardial stenosis or non-obstructive causes including coronary microcirculatory dysfunction and vasomotor disorders.
- Conditions
- Myocardial Ischemia, Non-Obstructive Coronary Atherosclerosis, Microvascular Coronary Artery Disease, Vasospastic Angina
- Trial name
- NCT04827498
- Testing
- Invasive coronary endothelium-dependent and non-endothelium-dependent physiological assessment
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Hospital San Carlos, Madrid
Fibrillation, Atrial, Coronary Artery Disease
Atrial Fibrillation and Non-obstructive Coronary Lesions
Atrial fibrillation (AF) is the most common cardiac arrhythmia associated with excessive risk of ischemic stroke and heart failure as well as reduced life expectancy.
- Conditions
- Fibrillation, Atrial, Coronary Artery Disease, Chronic Kidney Diseases
- Trial name
- AF-CAD (NCT04537507)
- Testing
- Coronary angiography
- Where
- 5 sites in Poland, Russia and 1 more
- Volunteers
- 8,000 people
- Sponsor
- Medical University of Bialystok
Myocardial Infarction With Non-Obstructive Coronary Artery, Myocarditis Acute
Comparison of Free-breathing 3D Quantitative Perfusion in Patients With MINOCA and MINOCA-mimics
This clinical study examines patients presenting with acute myocardial infarction and no significant coronary artery disease on coronary angiography (MINOCA) and patients with MINOCA-mimics with advanced CMR.
- Conditions
- Myocardial Infarction With Non-Obstructive Coronary Artery, Myocarditis Acute, Takotsubo Cardiomyopathy, Spontaneous Coronary Artery Dissection
- Trial name
- COPE-CMR (NCT06323811)
- Testing
- CMR
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- University of Zurich
Non-communicable Diseases (NCD), Neoplams
Health for Hungary (H4H) - Longitudinal Collection of Blood Samples and Corresponding Data
The Health for Hungary (H4H) study collects blood samples and corresponding health data to investigate healthy aging and health-to-disease transitions in middle-aged and elderly participants.
- Conditions
- Non-communicable Diseases (NCD), Neoplams, Cancer, Lung Cancer (NSCLC)
- Trial name
- H4H (NCT07743021)
- Where
- 33 sites in Hungary
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Center for Molecular Fingerprinting Research Nonprofit LLC
Angina Pectoris, Variant, Angina Pectoris; Spasm-Induced
ReACHallenge Trial: Acetylcholine Rechallenge After Pretreatment With Vasoactive Drugs
The goal of this clinical trial is to assess the feasibility and clinical value of acetylcholine (ACH) rechallenge after intracoronary verapamil +- nitroglycerine in a patient cohort with angina and non-obstructive coronary…
- Conditions
- Angina Pectoris, Variant, Angina Pectoris; Spasm-Induced, Angina Pectoris With Normal Coronary Arteriogram
- Trial name
- ReACHallenge (NCT05618132)
- Testing
- Acetylcholine rechallenge
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Antwerp