Clinical trials: Noncommunicable Diseases
Obesity, Knee Osteoarthritis
BLOOM Forward: Investigating Weight Loss Impact on TJAC Patients
The goal of this clinical trial is to prospectively assess the efficacy of the BLOOM program, a comprehensive weight loss dietary and lifestyle program, in a population of patients living with obesity and awaiting hip or knee…
- Conditions
- Obesity, Knee Osteoarthritis, Hip Osteoarthritis, Arthroplasty Complications
- Trial name
- NCT06103552
- Testing
- Building Lifestyle Options for Orthopedic Mobility (BLOOM)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Package of Essential Non-Communicable Diseases (PEN), Peer Coaching
PEN Implementation Study
There is a gap in the implementation of PEN services as well as in the monitoring and evaluation of the WHO PEN in Nepal. One reason for such gaps is due to a lack of team-based care in low-resource settings like Nepal.
- Conditions
- Package of Essential Non-Communicable Diseases (PEN), Peer Coaching, Clinical Audit, Mixed Method Implementation Study
- Trial name
- NCT05880784
- Testing
- Reinforcement of Peer coaching and clinical audit, Continuation of usual practice without intervention
- Where
- Nepal
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Shahid Gangalal National Heart Centre
Exercise
Community Based Promotion of Physical Activity in Nepal (COBIN-PA)
Globally, one in four adults does not meet the WHO-recommended level of physical activity. Insufficient physical activity is the fourth leading risk factor, contributing to 9% of global premature mortality.
- Trial name
- NCT06386692
- Testing
- FCHVs-led community based educational physical activity intervention
- Where
- Nepal
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
H. Pylori Infections, Non-communicable Diseases
Effects of Fermented Rye Bran Products on Helicobacter Pylori (HP) Infection and Metabolic Risk Factors
The investigators hypothesize that long-term fermented high-fibre rye intake may reduce the Helicobacter pylori infection through dampening inflammation and thereby leading to lower adherence of the bacteria to surfaces.The…
- Trial name
- RyeClaim (NCT03103386)
- Testing
- intake of food product with a patented fermented rye bran, intake of food product with common refined wheat
- Where
- China
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Fudan University
Hypertension, Diabetes
Development and Testing of a Sub-district Specific Model of 'Whole-of-government', and 'Whole-of-society' Approaches for the Prevention and Control of Non-communicable Diseases in a Sub-district of Bangladesh
Globally, non-communicable diseases (NCDs) are the leading cause of both mortality and morbidity. This intervention study aims to prevent and manage NCDs by adopting the World Health Organization's (WHO) comprehensive…
- Conditions
- Hypertension, Diabetes, Asthma, Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- NCT06453382
- Testing
- Behavioural change modification, Screening, NCD related knowledge practice and attitude
- Where
- Bangladesh
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- BRAC University
Cardiovascular Diseases, Non-Communicable Chronic Diseases
Intervention and Effect of Sleep Pattern on Cardio-cerebrovascular Disease
Because of the growing population of older people, cardio-cerebrovascular diseases has been the most important aging-related chronic disease, studying the pathogenesis and early warning mechanisms of cardio-cerebrovascular…
- Trial name
- NCT06294964
- Testing
- sleep education, behavioral education
- Where
- China
- Volunteers
- 12,800 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Surveys and Questionnaires, Noncommunicable Diseases
Use of Airtime Timing to Improve Interactive Voice Response Surveys in Bangladesh and Uganda
This study evaluates the effect of two different airtime incentive timings on interactive voice response (IVR) survey cooperation, response, refusal and contact rates, as compared to a control group, in Bangladesh and Uganda.
- Trial name
- NCT04513236
- Testing
- Pre-survey incentive, Post-survey incentive
- Where
- 2 sites in Bangladesh, Uganda
- Volunteers
- 2,287 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Cardiovascular Diseases (CVD), Type 2 Diabetes
Epigenetics and NCD Prevention in Kazakhstan: Personalized Approaches and Biological Age Prediction
This study aims to enhance personalized and preventive care for non-communicable diseases (NCDs) in Kazakhstan by examining epigenetic factors, predicting biological age and reproductive function using machine learning, and…
- Conditions
- Cardiovascular Diseases (CVD), Type 2 Diabetes, Chronic Respiratory Diseases, Obesity (Disorder)
- Trial name
- NCT06953180
- Testing
- Genetic: DNA analysis
- Where
- Kazakhstan
- Volunteers
- 6,720 people, healthy volunteers welcome
- Sponsor
- Asfendiyarov Kazakh National Medical University
Hyperlipidemia, Metabolic Syndrome X
Low Fat Plant-Based Supplemented Diet Effects on Risk Factors for Chronic Non-communicable Diseases
The effect of a diet free from animal-sourced nutrients on a variety of risk factors for chronic non-communicable diseases in weight reduction programs is not well established.
- Trial name
- LFPBDS2 (NCT02905448)
- Testing
- Low fat plant-based nutrition
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Barbara Jakše s.p.
Cardio Vascular Disease, Cardiovascular
African Studies on Aging and Noncommunicable Diseases Epidemiology
Despite the rising burden of noncommunicable diseases (NCDs), including cardiovascular diseases (CVDs), across Africa, high-quality evidence on the distribution of NCDs and their risk factors remains strikingly scarce.
- Conditions
- Cardio Vascular Disease, Cardiovascular, Cancer, Mortality
- Trial name
- ASANDE (NCT07427355)
- Where
- Senegal
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Alliance For Medical Research in Africa
Surveys and Questionnaires, Noncommunicable Diseases
Use of Airtime Structure to Improve Interactive Voice Response Surveys in Bangladesh and Uganda
This study evaluates the effect of three different airtime incentive structures on interactive voice response (IVR) survey cooperation, response, refusal and contact rates, as compared to a control group, in Bangladesh and Uganda.
- Trial name
- NCT03773146
- Testing
- 1X Airtime Incentive, Lottery Airtime Incentive
- Where
- 2 sites in Bangladesh, Uganda
- Volunteers
- 4,550 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Cardiovascular Diseases, Non-communicable Disease
Effects of Primary Prevention in Elderly People-The Healthy Aging Initiative
The number of elderly will increase rapidly in Europe in the next 30 years, which affects the country's economic and social development, welfare, health care, and also the individuals.
- Trial name
- HAI (NCT03312439)
- Testing
- Given advice
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Region Västerbotten
Childhood Obesity, Child Obesity
Corestability Training in Overweight Children
A total of 52 overweight children aged between eight and sixteen years will be recruited by criterion based purposive sampling to participate in the two groups pretest post test randomized clinical study.
- Conditions
- Childhood Obesity, Child Obesity, Children, Only
- Trial name
- NCT04315220
- Testing
- Corestability training, No Intervention
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Continuum of Care, Noncommunicable Diseases
Integrating Services for Noncommunicable Diseases in Continuum of Care for Mothers and Children
The objectives of this cluster randomized control trial are to examine the effect of combined intervention of the utilization of continuum of care (CoC) card and health education on the completion of CoC services among mothers…
- Trial name
- NCT03145155
- Testing
- Integrating services for noncommunicable diseases in continuum of care for mothers and children, Ordinary health education for pregnant women
- Where
- Japan
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Tokyo University
Major Risk Factors for Noncommunicable Diseases
A School-based Prevention Intervention to Promote Wellbeing in Preadolescents
This is a field study aiming to evaluate a school-based prevention intervention, Diario della Salute (DDS).
- Trial name
- DDS (NCT01720199)
- Testing
- Diario della Salute (DDS)
- Where
- Italy
- Volunteers
- 2,630 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale CN2 Alba-Bra
Child Development, Growth
Health and Early Life Microbiota
The aim of this cohort is to identify environmental, lifestyle and genetic factors that modify the human intestinal microbiota development during the first years of life, and to identify early microbiota features that associate…
- Conditions
- Child Development, Growth, Allergy, Overweight
- Trial name
- HELMi (NCT03996304)
- Where
- Finland
- Volunteers
- 1,055 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Surveys and Questionnaires, Noncommunicable Diseases
Use of Narrative Voice and Introduction Content to Improve Interactive Voice Response Surveys in Bangladesh and Uganda
This study evaluates the effect of two different narrative voices (one male and one female) and two different introductions (one with informational content and the other with additional motivational content) on interactive voice…
- Trial name
- NCT03772431
- Testing
- Female Voice, Motivational Introduction, Male Voice
- Where
- 2 sites in Bangladesh, Uganda
- Volunteers
- 5,580 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Acute Febrile Illness
Clinical Study of Transcriptome-based Diagnostic Biomarker for Acute Febrile Illness
Acute febrile illness is the main cause of outpatient visits，and bacterial and viral infections remains the most common cause. The diagnosis of infection is still based on symptoms and traditional techniques, resulting in overuse…
- Trial name
- NCT06552975
- Testing
- Infection
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Health Risk Behaviors, Healthy Lifestyle
Metaverse-Based Healthy Life Program for Youth
This study was planned within the scope of the call titled "Non-communicable diseases risk reduction in adolescence and youth (Global Alliance for Chronic Diseases - GACD)" with identity number HORIZON-HLTH-2022-DISEASE-07-03.
- Conditions
- Health Risk Behaviors, Healthy Lifestyle, Non Communicable Diseases, Health-Related Behavior
- Trial name
- MetaYouth (NCT05332886)
- Testing
- MetaHealth Group, MobileHealth Group
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Ayşegül İşler Dalgıç
Health-risk Behaviours, Non Communicable Diseases
Perception, Risk Behaviour, and Attitudes Related to Non-communicable Disease
The study is to explore the understanding of the perception, risk behaviour, and attitudes related to non-communicable diseases among adolescents and young adults. The objectives of the study are: 1.
- Trial name
- NCT07597434
- Where
- Hong Kong
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong