Clinical trials: Noninvasive
Healthy
Non-invasive Measurement of Glucose with Advanced Spectroscopy Techniques and Machine Learning Models
Primary aim of this pilot study is to provide evidence for a non-invasive, continuous, and transcutaneous measurement method to determine blood glucose levels robustly and accurately.
- Trial name
- NCT06406075
- Testing
- Lab demo 1.0
- Where
- Switzerland
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Liom Health AG
Spatial Navigation
Modulating Goal-directed Navigation Using Noninvasive Brain Stimulation
Our specific aim is to examine the effects of TMS on spatial processing during goal-directed navigation. In these experiments the investigators will utilize a scalp-recorded brain oscillation called right posterior theta that is…
- Trial name
- NCT05801861
- Testing
- Active 10-Hz TMS to the parietal cortex, Active single pulse TMS to the parietal cortex
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Healthy
Rad-67 Repeatability and Reproducibility
The primary objective of this clinical investigation is to evaluate the repeatability and reproducibility of using Rad-67 Pulse CO-Oximeter
- Trial name
- NCT04196907
- Testing
- Rad-67 Pulse CO-Oximeter and DCI Mini sensor
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Other Dental Disease/Condition of Teeth/Supporting Structure
Low-cost, Noninvasive Method to Assess Pulpal Vitality
The purpose of this research study is to find a new way of using light to measure the blood flow within the tooth. The researcher develop dental Laser Speckle imaging system tool that can use for exam condition of the tooth.
- Trial name
- NCT02271789
- Testing
- problematic tooth
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Primary Progressive Aphasia
Speech-Language Treatment With Remotely Supervised Transcranial Direct Current Stimulation in Primary Progressive Aphasia
Primary progressive aphasia (PPA) is a disorder characterized by gradual decline in speech-language ability caused by underlying neurodegenerative disease.
- Trial name
- NCT05901233
- Testing
- Remotely supervised Transcranial Direct Current Stimulation (RS-tDCS), Lexical Retrieval Training (LRT), Video Implemented Script Training in Aphasia (VISTA)
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Sports Performance
The Effect of Vagus Nerve Stimulation on Sportive Performance.
Performance is defined as the physiological potential required for an individual's physical activity. The sportive activity that he creates with his potential is defined as the sportive performance level of the individual.
- Trial name
- NCT05436821
- Testing
- Auricular vagus nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- İSMAİL CEYLAN
Cognitive Change
Cerebral Excitability and Cognitive Performance
This study investigates the perceptual and cognitive influences of low-intensity electrical brain stimulation (transcranial direct current stimulation; tDCS), versus control (sham) conditions.
- Trial name
- NCT03807934
- Testing
- Stimulation via Soterix Medical or Neuroelectrics noninvasive brain stimulation systems
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Tufts University
Parkinson Disease (PD)
Synthetic Vasomotion for Glymphatic Enhancement
The goal of this pilot clinical trial is to learn whether a week-long study combining controlled breathing procedures, intermittent exposure to a low-concentration carbon dioxide gas mixture, and noninvasive vagus nerve…
- Trial name
- NCT07814534
- Testing
- Active noninvasive vagus nerve stimulation, Active intermittent hypercapnia, Guided breathing
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Florida Institute for Human and Machine Cognition
Subclinical hypothyroïdism
Relationship of Noninvasive Assessment of Central BP With 10 Years Atherosclerotic CVD in Subclinical Hypothyroidism
verify Relationship of noninvasive assessment of central arterial blood pressure with 10 years Atherosclerotic Cardiovascular disease (ASCVD) in Subclinical hypothyroidism
- Trial name
- NCT06607978
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Insulin Dependent Diabetes, Non Insulin Dependent Diabetes
Evaluation and Comparison of Noninvasive Blood Glucose Concentrations
Comparison of noninvasive glucose measurement performance versus standard invasive reference measurements.
- Conditions
- Insulin Dependent Diabetes, Non Insulin Dependent Diabetes, Gestational Diabetes
- Trial name
- NCT01745900
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- VeraLight, Inc.
Portal Hypertension, Cirrhosis
Early Precise Diagnosis and Intervention of CPT Based on a Noninvasive 3D-vHPS
The aim of this study is to investigate the possibilities of early and precise management to decrease portal vein pressure in cirrhotic patients, guided by a non-invasive 3D-virtual-model of hepatic portal system (3D-vHPS).
- Trial name
- NCT02925975
- Testing
- Carvedilol, 3D-vHPS, Routine endoscopic procedures
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Changqing Yang
Stress, Physiological, Stress, Emotional
Psychophysiological Effects of Controlled Respiration and Mindfulness
The investigators aim to understand the effectiveness of 3 types of breathwork exercises and a mindfulness meditation control on improving psychological and physiological measures of wellbeing.
- Conditions
- Stress, Physiological, Stress, Emotional, Insomnia
- Trial name
- PECRM (NCT05304000)
- Testing
- Mindfulness Meditation, Cyclic Sighing Breathing, Box Breathing
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy Subjects
Novel Noninvasive Techniques to Study Neutrophil Airway Inflammation in an Ozone Challenge Model
The primary objective of this pilot study is to establish a model of neutrophil airway inflammation for future testing of anti-inflammatory substances in an early stage of clinical development.
- Trial name
- NCT00743704
- Testing
- ozoneexposure
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Hepatocellular Carcinoma (HCC), Cholangiocarcinoma
A Noninvasive and Screening miRNA Signature for Gastrointestinal Cancer
Gastrointestinal (GI) cancers remain a major global health burden, largely due to the lack of effective and accessible early screening strategies.
- Conditions
- Hepatocellular Carcinoma (HCC), Cholangiocarcinoma, Pancreatic Ductal Adenocarcinoma (PDAC), Esophageal Squamous Cell Carcinoma (ESCC)
- Trial name
- MiGIC (NCT07224750)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Gestational Diabetes
A Study Using Breath Tests to Identify Patients at Risk for Gestational Diabetes
The aim of our study is to evaluate the feasibility, and diagnostic value of oral 13C labelled glucose breath test compared to the GCT and OGTT tests.
- Trial name
- NCT07347262
- Testing
- Noninvasive Breath Test in Order to Identify Patients at Risk for Developing Gestational Diabetes
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Healthy
Accuracy of Noninvasive Pulse Oximeter Sensor (MightySat RX)
In this study, the level of oxygen within the blood will be reduced in a controlled manner by reducing the concentration of oxygen the study volunteer breathes.
- Trial name
- NCT03125135
- Testing
- MightySat RX Pulse Oximeter Sensor
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Liver Diseases
Identification of Hepatic Fibrosis Using 4D-MRI
To date, no specific treatment options exist for liver diseases, and there is a large global effort to find drugs that will halt liver disease progression in these patients.Liver fibrosis staging is essential as a…
- Trial name
- 4D-MRI Liver (NCT05385237)
- Testing
- 4D-MRI
- Where
- 2 sites in Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Ultrasonography
Ultrasonography of Optic Nerve Sheath Diameter for Noninvasive Detection of Raised Intracranial Pressure: ORIENT Study
This study aims to adopt a multi-center large sample size study to define (1) the normal range of Chinese ONSD; (2) ONSD diagnosis for patients with high intracranial pressure; (3) to analyze the correlation between ONSD and…
- Trial name
- NCT04981548
- Testing
- no intervention
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Pulmonary Hypertension
Diagnosis of Pulmonary Hypertension Using Cardiac Magnetic Resonance Images
In this study, study team aim to i) evaluate the accuracy of 3D IVS curvedness for prediction of RV systolic pressure (RVSP), mean pulmonary artery pressure (mPAP) and pulmonary vascular resistance (PVR) with RHC; ii) evaluate…
- Trial name
- NCT02790918
- Testing
- 6MWT, Cardiovascular Magnetic Resonance Imaging (CMRI)
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Heart Centre Singapore
Healthy Individuals, At Least 21 Years of Age
Noninvasive Blood Ethanol Measurement With Infrared Spectroscopy
The objective of this study is to assess the performance of a noninvasive device for the detection of blood alcohol levels.
- Trial name
- NCT01168102
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- InLight Solutions