Clinical trials: Normal Drug Tolerance
Potential Abnormality of Glucose Tolerance, Appetite; Lack or Loss, Nonorganic Origin
Short-term Effects of a Carob Snack on Postprandial Glycemic Responses and Energy Intake and Satiety
This study investigated any potential associations between two preloads offered as snacks and postprandial glycemic response, subjective and objective appetite and energy intake in healthy, normal-weight adults.
- Trial name
- NCT02935829
- Testing
- Glucose as reference food, White bread as reference food, Carob snack as test food
- Where
- Greece
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Acne Vulgaris
Double-blinded, Vehicle Controlled Study to Evaluate Efficacy & Tolerance of Bakuchiol and Ethyl Linoleate on Acne
Subjects will be assigned to a active cream or vehicle to compare the cosmetic effects. This will take place over a 12 week period.
- Trial name
- NCT05069272
- Testing
- Bakuchiol and Ethyl Linoleate, Vehicle
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ratan K. Chaudhuri
Acne Vulgaris
Study to Determine and Compare the Tolerance and Irritation Potential of Topical Acne Medications
This is a randomized, half-face study. On 1 side of the face, the subject will apply 1 of the 2 test products, clindamycin and benzoyl peroxide or dapsone gel and the contra lateral side of the face will remain non-treated to…
- Trial name
- NCT00964366
- Testing
- clindamycin and benzoyl peroxide, Dapsone gel
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Type 2 Diabetes, Impaired Glucose Tolerance
Effects of Pinitol on Hidrocarbonated Metabolism Parameters in Diabetic, Impaired and Normal Fasting Glucose Subjects
The purpose of this study was to assess whether pinitol improves hidrocarbonated metabolism parameters, and evaluate its effect on oxidative stress and endothelial function in diabetic, impaired and normal fasting glucose…
- Conditions
- Type 2 Diabetes, Impaired Glucose Tolerance, Healthy
- Trial name
- NCT01754792
- Testing
- Pinitol
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Safety Issues
A Phase I Clinical Study of Hemay808
This is a first-in-human study in health volunteers. The purpose is the local tolerability and systemic safety of Hemay808, which is an ointment made of a novel small molecule Hemay028.
- Trial name
- NCT04100642
- Testing
- Hemay808
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tianjin Hemay Pharmaceutical Co., Ltd
Glucose Intolerance
Dorzagliatin and 1st Phase Insulin and Beta-cell Glucose Sensitivity in IGT and NGT
Dorzagliatin, a novel dual allosteric activator of glucokinase. reduces blood glucose by increasing insulin secretion by enhancing sensitivity of beta cells to glucose.
- Trial name
- NCT05468229
- Testing
- Dorzagliatin
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults
The purpose of this clinical trial is to find out whether one type of fish oil works better than another at improving metabolic health in people who are at high risk of developing type 2 diabetes.
- Conditions
- Type 2 Diabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetes / Type 2 Diabetes, Obesity & Overweight
- Trial name
- END-T2D (NCT07575438)
- Testing
- Fish Oil, Corn oil control
- Where
- Canada
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- May Faraj, PDt, PhD
Potential Abnormality of Glucose Tolerance, Appetitive Behavior
Effects of Bran Size on Glycemic Responses
This study investigated the effects of bran's particle size on glycemic responses
- Trial name
- NCT03314142
- Testing
- Glucose as reference food, White bread as reference food, Bread enriched with coarse wheat bran
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Acne
Management of Side-Effects of Anti-Acne Treatment by a Cosmetic Routine
Retinoid-based topical acne treatment may induce local tolerance issues such as erythema, dryness, stinging and burning sensations that may reduce adherence and efficacy.
- Trial name
- NCT05486910
- Where
- Poland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Atopic Dermatitis (AD)
Tolerance Evaluation of a Nighttime Moisturizing Balm on Babies and Adults With Eczema
The purpose of this 14-day, two phase clinical study is to test the tolerance of a new over-the-counter moisturizing balm on subjects with eczema.
- Trial name
- NCT02357940
- Testing
- Experimental Product
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)