Clinical trials: Normal Labor
Obstetrics, Labor
Clinical Feasibility of Birth- Track II System
The Study purpose is to monitor the cervix dilation, head descent, FHR and to follow contraction in a women in active labor.
- Trial name
- BT (NCT00840710)
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Barnev Ltd
Placenta Accreta, Third Trimester
A Serum Galectin-3 Levels in Placenta Accreta Spectrum Pregnancies
Placenta Accreta Spectrum (PAS) represents a significant cause of maternal morbidity and mortality, causing complications that surpass those posed by most routine obstetric issues.
- Trial name
- NCT05945446
- Testing
- Galectin 3
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Labor Pain and to Reduce Pain, Childbirth
Breathing Exercises Guided by Student Midwives During Labor
This randomized controlled trial aimed to evaluate the effect of breathing exercises applied under the guidance of student midwives during labor on labor pain, labor duration, and birth satisfaction.
- Conditions
- Labor Pain and to Reduce Pain, Childbirth, Normal Labor
- Trial name
- BREATH (NCT07357246)
- Testing
- Guided Breathing Exercises During Labor, Routine Intrapartum Care
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Antalya Bilim University
Low Back Pain
Subcutaneous Sterile Water Injection for Relief of Low Back Pain
To compare the effect of subcutenous sterile water injection technique with the subcutaneous saline injection technique in the degree and duration of low back pain-relieving during childbirth
- Trial name
- NCT02813330
- Testing
- Subcutaneous sterile water injection, saline injection
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Cesarean Delivery Affecting Fetus, Labor Dystocia
Early Diagnosis and Intervention for Fetal Malposition in Active Labor and Its Impact on Mode of Delivery
The goal of this randomized trial is to test if changing a person's position in labor can increase the chances of delivering their baby vaginally.
- Conditions
- Cesarean Delivery Affecting Fetus, Labor Dystocia, Labor Complication
- Trial name
- NCT05881629
- Testing
- Maternal position change to side-lying lateral with peanut ball, Free maternal position
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Labor
Evaluation of Laborpro - a New Device for the Assessment of Progress of Labor
A clinical study was conducted to demonstrate the accuracy of the LaborPro System in measuring fetal head station (from the pelvic inlet), cervical dilatation, and fetal head position against manual/digital examination.
- Trial name
- NCT00827229
- Testing
- Labor Monitor
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Trig Medical Inc
Labor Pain
Left Lateral Position vs Supine Position to Reduce Active Labor Duration
This randomized clinical trial aims to compare the effect of the left lateral decubitus position versus the supine position on the duration of the active phase of labor in nulliparous women.
- Trial name
- DLI-SP (NCT07411352)
- Testing
- Left Lateral Decubitus Group, Supine Position Group
- Where
- Honduras
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Tinea Capitis
Efficacy and Safety of Topical Amphotericin B Solution in Treatment of Resistant Tinea Capitis in Children 16 Years Old or Less we Follow up Cases Weekly up to 8 Weeks and Notice Improvement of Itching ,Scaling, and Hair Regrowth Then Fungal Culture Done to See if the Solution Working
The goal of this clinical trial is to learn if topical amphotericin b solution works to treat resistant cases of tinea capitis in children. It will also learn about the safety of drug.
- Trial name
- prospective (NCT06980493)
- Testing
- Amphotericine in liposome (Ambisome®)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sohag University
Normal Physiology
Modulation of the Parieto-frontal Communication
Background: Research shows that the parietal and prefrontal areas of the brain are involved in short-term memory. Researchers want to look at the effects of transcranial magnetic stimulation (TMS) of these areas on short-term…
- Trial name
- NCT03434093
- Testing
- Transcranial Magnetic Stimulation (TMS), Working Memory Task
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
A Study to Learn How Elinzanetant Moves Into, Through, and Out of the Body, How Safe it is, and How it Affects the Body in Participants With Kidneys That do Not Work as Well as They Should Compared to Participants Whose Kidneys Work Normally
Researchers are looking for a better way to treat people who have vasomotor symptoms (VMS). The symptoms of VMS are hot flashes. These symptoms can be caused by changes in sex hormone levels.
- Trial name
- NCT05071729
- Testing
- Elinzanetant (BAY3427080)
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Bayer
Renal Impairment, Healthy Volunteers
A Study of ASP0367 in People With Kidneys That do Not Work Well and in Healthy People
This study is for adults whose kidneys do not work well (renal impairment) and adults whose kidneys work normally. This study will provide more information on a potential new treatment, called ASP0367.
- Trial name
- NCT05117294
- Testing
- Bocidelpar
- Where
- 4 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Global Development, Inc.
Normal Labor, Obstetric Labor Complications
Sonopartogram. The Next Step in the Delivery Room
Objectives: Evaluation of the correlation between the sonographic parameter and clinical findings (e.g. digital examination) in any cephalic (not only occipital anterior) position Examination of the relationship between various…
- Trial name
- SONOLABOR (NCT02326077)
- Testing
- Ultrasound, Acceptability of ultrasound monitoring of labor, Patients' experience regarding intrapartum ultrasound
- Where
- 2 sites in Greece, Romania
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy Craiova
Preterm Birth, Oxygen Toxicity
Fetal Haemoglobin and Cerebral and Peripheral Oxygenation.
The aim of this study is to investigate the relationship between cerebral and peripheral oxygenation and oxygen extraction, as measured by NIRS (near-infrared spectroscopy ), and the FHbF (fraction of fetal hemoglobin) and…
- Conditions
- Preterm Birth, Oxygen Toxicity, Fetal Hemoglobin
- Trial name
- HbFIN (NCT04802629)
- Testing
- Near-infrared spectroscopy
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Labor Pain, Labor Duration
Effects of the Rebozo Technique During Active Labor on Labor Pain and Labor Duration in Primiparous Women
Study Description Childbirth is a physiological process often accompanied by severe pain and prolonged labor, which may negatively affect maternal well-being and increase the likelihood of obstetric interventions.
- Conditions
- Labor Pain, Labor Duration, Childbirth, Management of Delivery
- Trial name
- Rebozo Techniq (NCT07759479)
- Testing
- Rebozo technique, Routine Intrapartum care
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Infant, Newborn, Infant, Low Birth Weight
Inflammatory Cytokines Associated With Perinatal Brain Injury
This observational study assessed whether measurements of certain pro-inflammatory and anti-inflammatory cytokines in the blood (either singly or in combination) at birth and/or up to day of life 21 can predict cerebral palsy at…
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- Cytokines (NCT01035697)
- Where
- 18 sites in United States
- Volunteers
- 1,067 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Normal Pregnancy
Comparative Affect of a Continuous Epidural Infusion of Clonidine During Labour. Prospective Double Blind Randomized Trial
Addition of clonidine to an epidural mixture of local anaesthetic and morphine improves analgesia and reduces the frequency of motor blockade during epidural analgesia.
- Trial name
- NCT00437996
- Testing
- Clonidine, Levobupivacaine, Sufentanil
- Where
- 2 sites in France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Preterm Labor, Periodontitis
Inflammatory Cytokines in GCF and Placental Tissues in Chronic Periodontitis Patients With Preterm Delivery
Investigators have shown the presence of elevated proinflammatory cytokines in amniotic fluid in patients in preterm labor.However, there is limited and mostly negative evidence that the elevation of these mediators in gingival…
- Trial name
- NCT02521688
- Testing
- incisional biopsy from placenta and GCF sample
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Neonatal Hypothermia, Brown Adipose Tissue
Investigation of the Mechanisms of the Tendency to Hypothermia in Newborns and Premature Neonates
Newborns have thermoregulatory mechanisms that differ from those of adults. Instead of producing heat through shivering, newborns primarily rely on non-shivering thermogenesis by the brown adipose tissue.
- Conditions
- Neonatal Hypothermia, Brown Adipose Tissue, Preterm and Term Infants, Neonate
- Trial name
- NCT06803069
- Where
- 2 sites in Hungary
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Labor
The Endocannabinoid System in Human Gestational Tissues in Labor
The purpose of this research study is to determine if the endocannabinoid (a biological system) plays a role in the labor process.
- Trial name
- NCT03752021
- Testing
- Myometrial Sampling
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Umbilical Cord of Normal Labor
CD49 in Optimization The Cologenicity of Mesenchymal Stem Cell Culture Passage
Human mesenchymal stem cells (MSCs) due to their regenerative and immunomodulatory properties are widely used for the treatment of bone and cartilage damage, cardiovascular, gastrointestinal, autoimmune, neurodegenerative…
- Trial name
- NCT05093725
- Testing
- flow cytomery
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sohag University