Clinical trials: Normal Volunteers
Healthy, Pulmonary Fibrosis
Identification of Genes Associated With Lung Disease in Patients With Rheumatoid Arthritis
Pulmonary fibrosis (PF) is a condition in which the lungs of a patient become scarred and fibrous. It has been known to occur in as many as 40% of patients diagnosed with rheumatoid arthritis (RA).
- Conditions
- Healthy, Pulmonary Fibrosis, Rheumatoid Arthritis
- Trial name
- NCT00001885
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthy Volunteers
Spirulina Oral Supplement for Enhancing Host Resilience to Virus Infection
This randomized, double blind, placebo controlled study aims to establish the impact of the oral supplement, Immulina TM, on enhancing host resilience to the effects of viral influenza infection in humans.
- Trial name
- NCT05447078
- Testing
- Immulina TM
- Where
- United States
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Healthy
Phase 1 PK, Bioavailability, Safety Study of Clonidine MBT w Catapres in Healthy Volunteers
The purpose of this study is to determine the pharmacokinetic dose proportionality of 50 μg and 100 μg Clonidine and comparative bioavailability of clonidine with that from the Reference drug, Catapres® 100 μg oral tablets…
- Trial name
- NCT02548806
- Testing
- Clonidine MBT 50µg, Clonidine MBT 100µg, Catapres 100μg
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valerio Therapeutics
Alopecia
A Clinical Traial to Assess Pharmacokinetic/Pharmacodynamic Profiles and Safety of CKD-843
A Clinical Traial to Assess Pharmacokinetic/Pharmacodynamic Profiles and Safety of CKD-843
- Trial name
- NCT04805606
- Testing
- CKD-843 A, CKD-843 B, CKD-843-R
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Schizophrenia, Memory Disorders
The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) Genotype
This study will evaluate whether Atomoxetine improves cognition in healthy volunteers as well as patients with schizophrenia. Atomoxetine is a drug that has been Food and Drug Administration (FDA) approved for Attention Deficit…
- Conditions
- Schizophrenia, Memory Disorders, Cognition Disorders
- Trial name
- Atomoxetine (NCT00548327)
- Testing
- Atomoxetine, Functional magnetic resonance imaging, Neuropsychological Testing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Healthy Volunteers
Spatial and Dynamic Characterization of Brain Activity for Language and Posture (Verticality) During Normal Aging. Magnetoencephalography (MEG) Study (MEG-AGING)
Depending on the point of view, different definitions of aging have been proposed. Thus, at the biological level, aging corresponds to a natural physiological process that leads to the progressive degeneration of cells and the…
- Trial name
- MEG-AGING (NCT04036162)
- Testing
- Cognitive tasks
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Rheumatoid Arthritis
Cross-over Study to Investigate Retinal Function Following Administration of a Single Dose of AZD9056
The purpose of the study is to determine whether treatment with a single 800mg dose of AZD9056, a medication which has been developed as a possible treatment for Rheumatoid Arthritis, has an effect on the function of the retina
- Trial name
- NCT00700986
- Testing
- AZD9056
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy, Schizophrenia
Eye Blink Response in Healthy Volunteers and Adults With Schizophrenia
The purpose of this study is to explore how the brain works during particular memory tasks in people with schizophrenia and healthy volunteers.
- Trial name
- NCT00001920
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Allergic Conjunctivitis
Study Evaluating the Safety of KetoNaph Ophthalmic Solution in Healthy Volunteers
This study is being conducted to evaluate the safety of KetoNaph ophthalmic solution in healthy adult subjects and in pediatric subjects with a history or family history of ocular allergy.
- Trial name
- NCT01159015
- Testing
- KetoNaph, Vehicle
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Healthy
To Study the Mechanisms of Acupuncture Through Functional Magnetic Resonance Imaging and Peripheral Neurosensory Testing
Acupuncture may affect nerve functions. This study assesses the effect of acupuncture on both the peripheral and the central nerve systems
- Trial name
- NCT00521547
- Testing
- Electroacupuncture
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Safety and Tolerability in Healthy Volunteers
A Single and Multiple Ascending Dose Study of ANX009 in Normal Healthy Volunteers (NHV)
The purpose of this study is to evaluate the safety, tolerability, pharmakokinetics and pharmacodynamics of single and repeated doses of ANX009
- Trial name
- NCT04535752
- Testing
- ANX009
- Where
- Australia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Annexon, Inc.
Normal Physiology
Collection of Peripheral Blood Stem Cells Using G-CSF and Plerixafor in Normal Volunteers
Background: Many treatments for immune system disorders involve the use of stem cells that have been collected from blood marrow.
- Trial name
- NCT01123499
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Healthy Human Volunteers With Visibly Tanned Skin
A Proof-of-Concept, Safety and Efficacy Study of SkinQ Glow Bright Wonder Mask in Healthy Human Subjects
This is an open-label, single-arm, single-centre, proof-of-concept, safety and efficacy, clinical study of SkinQ Glow Bright Wonder Mask in Healthy Human Subjects and adequate representation of varied skin types [Normal, Oily…
- Trial name
- NCT05499247
- Testing
- SkinQ Glow Bright Wonder Mask
- Where
- India
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Acute Coronary Syndrome
99th Percentile Upper Reference Limit (URL) for the Meritas Troponin I Test
Prospective multicenter sample collection and testing study.
- Trial name
- NCT02638311
- Where
- 3 sites in United States
- Volunteers
- 769 people, healthy volunteers welcome
- Sponsor
- Trinity Biotech
Healthy Volunteers
A Phase 1 Study of SMP-100 in Normal Healthy Volunteers
This will be the first clinical study of oral administration SMP-100 in healthy subjects. The proposed randomized Phase 1 trial is a double-blind, placebo-controlled, single and multiple ascending dose study in approximately 72…
- Trial name
- NCT04296799
- Testing
- SMP-100
- Where
- Australia
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Chengdu SciMount Pharmatech Co., Ltd.
Heart Disease
Cardiac Elastography to Determine Strain and Strain Rates in the Heart
Cardiac elastography is a new technique to analyze strain and strain rates in many organ systems, including the heart. In this study, cardiac elastography derived from the analysis of raw radiofrequency data obtained from a…
- Trial name
- NCT00205387
- Testing
- cardiac elastography and echocardiography
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy
Drug-Drug Interaction Study: ASP2151 and Ciclosporin
ASP2151 is an experimental treatment for herpes. Patients undergoing organ and tissue transplantation may be prescribed ciclosporin to suppress their immune system to give the transplant an increased chance of not being rejected.
- Trial name
- NCT02280421
- Testing
- ASP2151 400mg + 100mg ciclosporin, ASP2151 1200mg + 100mg ciclosporin
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Maruho Europe Limited
Chronic Obstructive Pulmonary Disease
Safety, Tolerability, and Pharmacodynamic Effect Study of PUR118
The purpose of this study is to establish single and multiple dose safety in healthy subjects and subjects with mild chronic pulmonary obstructive disease (COPD).
- Trial name
- NCT01333904
- Testing
- PUR118
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pulmatrix Inc.
Normal Subject / Healthy Volunteers
VitalFlow Healthy Volunteer Study
Find the stimulation threshold of the facial nerve (ganglion Geniculate) associated with tolerability and safety in subjects Healthy humans.
- Trial name
- NCT03487393
- Testing
- magnetic facial nerve stimulation
- Where
- Mexico
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Nervive, Inc.
Healthy
Dose Response of Intravenous Sincalide(CCK-8) for Gallbladder Emptying
This is a clinical research study to establish normal values for the infusion of a synthetic form of the hormone cholecystokinin(CCK-8) for gallbladder emptying.
- Trial name
- NCT00685477
- Testing
- Experimental Sequence ABC, Experimental Sequence ACB, Experimental Sequence BAC
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Temple University