Clinical trials: Normative, open to volunteers
Hypoactive Delirium
The Basel BOMP-AID Randomized Trial
Delirium is a neurobehavioural syndrome that frequently develops in the postoperative and/or ICU setting. The incidence of elderly patients who develop delirium during hospital stay ranges from 11-82%.
- Trial name
- BOMP-AID (NCT03438526)
- Testing
- Melatonin (Circadin ®)
- Where
- Switzerland
- Volunteers
- 190 people
- Sponsor
- University Hospital, Basel, Switzerland
Hypopharyngeal Peak Pressure
Normative Swallowing Physiological Metrics of Pharyngeal High-Resolution Impedance Manometry in Chinese Adults
As Taiwan enters a super-aged society in 2025, the number of elderly patients and patients with multiple comorbidities continues to increase, and the risk of dysphagia rises with advancing age.
- Trial name
- NCT07594561
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healthy
Anthropometric Normalization in Inter-Individual Variability of Comprehensive Isokinetic Strength Assessment
Accurate normalization of peak torque (PT) is critical for comparing muscle strength across individuals of varying body composition.
- Trial name
- PT (NCT07508150)
- Testing
- effects of BW versus BMI normalization on inter-individual variability of trunk, hip, and knee muscle strength in healthy female
- Where
- Egypt
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Cairo University
Perinatal Depression, Perinatal Anxiety
Effectiveness and Implementation of a Personalized mHealth Intervention for the Universal Prevention of Maternal Perinatal Mental Disorders
This study is part of the ERC-funded e-Perinatal project and represents a large-scale hybrid type 1 effectiveness-implementation cluster randomized controlled trial.
- Trial name
- ePerinatal-RCT (NCT07613008)
- Testing
- The e-Perinatal intervention is a personalized mobile health (mHealth) program, Standard routine maternal care
- Where
- Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Seville
Normal Pediatric Swallowing Physiology, Swallowing Muscle Activation Patterns in Children
Surface Electromyographic Analysis of Normal Swallowing in Children: An Exploratory Study
This exploratory clinical trial aims to investigate the mechanism of sequential muscle contractions during normal swallowing processes, including spoon, straw, and cup feeding, in children aged 2 to under 10 years without…
- Conditions
- Normal Pediatric Swallowing Physiology, Swallowing Muscle Activation Patterns in Children, Swallowing Function
- Trial name
- NCT07455279
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Binocular Visual Function
Pilot Study of Normative Range of Field of Binocular Single Vision in Adults in Singapore
The assessment and monitoring of the field of binocular single vision remains a crucial aspect of ophthalmological care, yet current clinical practice relies on normative standards established by Feibel \& Roper-Hall in 1974 that…
- Trial name
- NORVIBAS (NCT07257341)
- Testing
- Field of Binocular Single Vision
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Healthy Eyes
Clinical Investigation of MAIA Microperimeter Device: Mesopic Normative Database Collection
The purpose of this pre-market, multicentric cross-sectional study is to create a mesopic Normative Database for a new version of the MAIA device. Moreover, the study aims to evaluate MAIA safety and adverse events.
- Trial name
- NCT06991127
- Testing
- MAIA
- Where
- 3 sites in United States, Australia and 1 more
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Centervue SpA
Children, Only, Vestibular Function
Normative Data of Vestibular and Postural Function in Danish Children
The goal of this age-based cohort study is to provide normative data of vestibular function in the general Danish pediatric population.
- Trial name
- VASIC (NCT06229730)
- Testing
- video Head Impulse Test, Cervical Vestibular Evoked Myogenic Potential, Ocular Vestibular Evoked Myogenic Potential
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gødstrup Hospital
Primary Biliary Cholangitis
Study of Saroglitazar Magnesium for PBC Patients With Incomplete Response or Intolerant to UDCA Therapy
Study of Saroglitazar Magnesium for PBC Patients with Incomplete Response or Intolerant to UDCA Therapy
- Trial name
- EPICS-IV (NCT07424677)
- Testing
- Saroglitazar Magnesium 1 mg
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Zydus Therapeutics Inc.
Aging, Dementia Alzheimers
Localized Analysis of Normalized Distance From Scalp to Cortex and Personalized Evaluation (LANDSCAPE)
Scalp to cortex distance (SCD), as a key technological parameter of brain stimulation, has been highlighted in the guidelines of non-invasive brain stimulation.
- Conditions
- Aging, Dementia Alzheimers, Parkinson Disease, Dementia Frontotemporal
- Trial name
- NCT05967390
- Testing
- Transcranial Magnetic Stimulation
- Where
- Hong Kong
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke, Alzheimer s Disease
Development, Validation and Normative Data of the Italian Battery for the Recognition of Famous Faces (FAME)
The I-FACE project aims to develop and validate a battery to assess famous-face recognition in people with neurodegenerative diseases and stroke.
- Conditions
- Stroke, Alzheimer s Disease, Frontotemporal Degeneration (FTD)
- Trial name
- I-FACE (NCT07911878)
- Testing
- Neuropsychological assessment using the I-FACE battery
- Where
- 10 sites in Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Muscle Strength, Healthy
Reference Equations and Normative Data for Isometric Quadriceps and Handgrip Muscles STrength in Southern European Populations - RESTart: a Multicentre Study
This observational study aims to learn about peripheral muscle strength in healthy adults and people with chronic respiratory diseases.
- Conditions
- Muscle Strength, Healthy, Chronic Respiratory Diseases
- Trial name
- RESTart (NCT07628530)
- Where
- Spain
- Volunteers
- 2,815 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Anorexia Nervosa
Ketogenic Diet and Brain Response in Anorexia Nervosa
This is a longitudinal study with an open design in weight recovered anorexia nervosa (wrAN) individuals. Healthy controls (HC) will also be assessed.
- Trial name
- NCT06540703
- Testing
- Therapeutic Ketogenic Diet (TKD)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anorexia Nervosa
The Fecal Microbiome Transplant (FMT) Study for Anorexia Nervosa
Anorexia Nervosa (AN) is a severe, debilitating and potentially life threatening illness that is difficult to treat. A cardinal symptom of AN is the mistaken belief on the part of the individuals that they are overweight and must…
- Trial name
- NCT07143981
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Healthy Volunteer
Augmenting Existing Normative Data for QbMobile in Healthy Children Aged 6-11 Years
The purpose of this study is to strengthen the normative QbMobile data for children and adolescents age 6-11 years to allow for a more robust and accurate representation when comparing a patient's QbMobile performance with the…
- Trial name
- NCT07330960
- Testing
- Digital software application for cognitive performance and activity measurement (QbMobile, investigational device)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Qbtech AB
Cortical Development Malformation, Multiparametric Magnetic Resonnance Imaging
Normative Brain Volume Profiles From Multicenter Fetal MRI
Fetal brain MRI is an essential diagnostic tool to inform parents about the prognosis of abnormalities detected on routine ultrasound.
- Conditions
- Cortical Development Malformation, Multiparametric Magnetic Resonnance Imaging, Brain Cortical Thickness, Prenatal Diagnosis
- Trial name
- MULTINORMFET (NCT06081036)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 1,423 people, healthy volunteers welcome
- Sponsor
- Assistance Publique Hopitaux De Marseille
Grip Strength, Normative Values
Normative Hand Grip Strength Values in Swedish Male and Female Ice Hockey Players Across Competitive Levels
This study measures hand grip strength in male and female ice hockey players across different Swedish leagues to create reference (normative) values for adult players.
- Conditions
- Grip Strength, Normative Values, Ice Hockey Players
- Trial name
- NCT07567547
- Volunteers
- 800 people
- Sponsor
- Dalarna County Council, Sweden
Stigma, Social, Help-Seeking Behavior
Personalized Normative Feedback for Stigma and Help-seeking
People tend to care about what others think and often change our behaviors accordingly. But what if people do not have an accurate understanding of what others really think? Stigma is pervasive, especially in the Black and Asian…
- Trial name
- NCT07683819
- Testing
- Personalized Normative Feedback (PNF), Attention control
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Han Oh