Clinical trials: Nose Bleed
Epistaxis
Medico-economic Evaluation of Management Strategies for Severe Epistaxis
Current recommendations consider surgical ligation and supra-selective embolization as equivalent in terms of efficacy and there is no clear consensus to choose between one and the other technique.
- Trial name
- EPICOST (NCT05281952)
- Testing
- endoscopic ligation, Supra-selective embolization
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Toulouse
Epistaxis
A Prospective Randomised Controlled Trial of Management of Recurrent Nosebleeds in Children
To determine whether the selective application of a combined treatment regimen of silver nitrate cautery and 4 weeks of Naseptin cream is superior to naseptin treatment alone in the management of recurrent paediatric epistaxis.
- Trial name
- NCT00390663
- Testing
- Nasal Cautery
- Where
- United Kingdom
- Volunteers
- 216 people
- Sponsor
- NHS Greater Glasgow Yorkhill Division
Hereditary Hemorrhagic Telangiectasia
Tranexamic Acid and Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT)
Hereditary hemorrhagic telangiectasia (HHT, Rendu-Osler-Weber Syndrome) is associated with frequent nosebleeds in the majority of cases.
- Trial name
- TAHHT (NCT01031992)
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- University Hospital, Saarland
Epistaxis
Usage of Orange Peel Extract in Management of Epistaxis
Efficacy of orange peel extract in treatment of epistaxis in children
- Trial name
- NCT06836102
- Testing
- Orange
- Volunteers
- 60 people
- Sponsor
- Minia University
Le Fort; I, Blood Loss
Impact of Different Instrument Modifications on Lateral Nasal Wall Osteotomy and Pterygomaxillary Separation in Le Fort I Surgery
The aim of this study is to investigate the effect of different instrument modifications on the customized osteotomy of the lateral nasal wall in Le Fort I surgery, focusing on the level of lateral nasal wall fractures and the…
- Trial name
- NCT06629935
- Testing
- orthognathic surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Epistaxis, Intubation Complication
The Effect of Bevel Direction on the Pathway of the Nasotracheal Tube
In this study, the subjects are divided into two groups (group I: intervention group = the nasotracheal tube inserted with the bevel of the nasal tube facing the direction of the patient's head, and Group II: conventional group =…
- Trial name
- NCT03740620
- Testing
- Bevel facing the cephalad direction of the patient, Bevel facing leftward of the patient
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hereditary Hemorrhagic Telangiectasia (HHT)
Submucosal Bevacizumab for the Management of Recurrent Epistaxis in Patients With Hereditary Hemorrhagic Telangiectasia (HHT)
This is a research study to find out more about the use of Avastin (proper chemical name is bevacizumab) in the treatment of epistaxis (nose bleeding) in patients with Hereditary Hemorrhagic Telangiectasia (HHT).
- Trial name
- NCT01402531
- Testing
- Submucosal Bevacizumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Diego
Nasal Bleeding
Epinephrine Nebulization Prior to Nasotracheal Intubation
This randomised, prospective study performed in Ain shams university hospitals over 126 Patients ASA I and ASA II, trauma patients who suffered isolated mandibular fractures and necessitated nasal intubation during general…
- Trial name
- NCT05738564
- Testing
- Epinephrine Inhalation Solution
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Ain Shams University
Ecchymosis
The Utility of Peri-operative Arnica Montana for Reduction of Ecchymosis in Rhinoplasty Surgery
Arnica montana is a homeopathic drug that is made in accordance with the official methods of the Homeopathic Pharmacopoeia of the United States (HPUS) and is commonly used by cosmetic surgeons throughout the world, although there…
- Trial name
- NCT01164644
- Testing
- Arnica montana
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Wisconsin, Madison
Malocclusion, Open Bite
Effect of Customized Lateral Nasal Wall Osteotomy on the Pterygomaxillary Separation During le Fort I Down-fracture
The goal of this clinical trial is to show the effect of patient specific lateral nasal wall osteotomy to the pterygomaxillary separation during Le Fort I down-fracture. Participants will be divided into two treatment groups.
- Conditions
- Malocclusion, Open Bite, Le Fort; I, Orthognathic Surgery
- Trial name
- NCT06233188
- Testing
- orthogantic surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Bezmialem Vakif University
Supraglottic Airway Obstruction, Airway Complication of Anesthesia
Wei Nasal Jet Tube vs Nasal Cannula Oxygen Support in Gastrointestinal Endoscopy Patients
Sedoanalgesia is applied to patients during gastrointestinal endoscopy. Sedoanalgesia may cause respiratory depression and hypoxia in patients.
- Conditions
- Supraglottic Airway Obstruction, Airway Complication of Anesthesia, Airway Obstruction, Anesthesia Complication
- Trial name
- NCT05783050
- Testing
- Wei Nasal Jet Tube, Nasal Cannula Oxygen Support
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Epistaxis, Recurrent Epistaxis
Nurse-Delivered First-Aid Education for Recurrent Pediatric Epistaxis
Nosebleeds (epistaxis) are common in children and can cause anxiety for children and their caregivers. Although most nosebleeds can be managed at home using simple first-aid techniques, caregivers may not know the correct steps…
- Trial name
- NCT07898644
- Testing
- Nurse-Delivered First-Aid Education, Usual Care
- Where
- Egypt
- Volunteers
- 144 people
- Sponsor
- Cairo University
Anterior Epistaxis, Tranexamic Acid
Tranexamic Acid Dosage for Topical Treatment of Anterior Epistaxis
Patients with epistaxis usually apply to the emergency department for initial treatment. According to recent research, tranexamic acid is effective in the treatment of epistaxis.
- Trial name
- Tranexamicacid (NCT06183918)
- Testing
- Tranexamic acid, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people
- Sponsor
- Izmir Ataturk Training and Research Hospital
Von Willebrand Disease (VWD)
Algorithm-based Management to Reduce the Recurrence of GI Bleeding and Severe Epistaxis in Von Willebrand Disease
WILL MANAGE is a prospective multicenter controlled open label randomized trial comparing an algorithm-based multidisciplinary management to a standard of care to reduce the incidence of bleeding (GI bleeding or severe epistaxis)…
- Trial name
- WILL MANAGE (NCT06651255)
- Testing
- Optimized management, Standard of care management
- Where
- 17 sites in France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Lille
Nasotracheal Intubation
Nostril Side on Epistaxis
The purpose of the study is to investigate the effect of the nostril side on epistaxis during nasotracheal intubation.
- Trial name
- NCT06605989
- Testing
- Nasotracheal intubation
- Where
- 2 sites in South Korea
- Volunteers
- 208 people
- Sponsor
- Seoul National University Hospital
Nasal Surgery, Anesthesia
Remifentanil vs. Nicardipine for Controlled Hypotension in Elective Nasal Surgery
This study compares remifentanil infusion versus nicardipine infusion for controlled hypotension during elective nasal surgery. Both agents are standard clinical methods.
- Conditions
- Nasal Surgery, Anesthesia, Controlled Hypotension for Nasal Surgeries
- Trial name
- NCT07660562
- Testing
- Nicardipine, Remifentanil
- Volunteers
- 44 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Epistaxis
Effect of Practical Demonstration to Use Nasal Spray and Apply Intranasal Ointment on Epistaxis
To compare the result of verbally educating the parents about method of intranasal antiseptic cream application versus practically educating and demonstrating how to apply cream intra nasally.
- Trial name
- NCT04217941
- Testing
- Health education with practical demonstration of nasal ointment, Health Education and practical demonstration of Nasal spray and intranasal ointment
- Where
- Pakistan
- Volunteers
- 300 people
- Sponsor
- Combined Military Hospital, Pakistan
Epistaxis, Nasal Obstruction
The Effect of Packing in Post Operative Management of FESS
Chronic sinusitis is a very common problem. The functional endoscopic sinus surgery is a prevalent option to treat this disease.During usage of different techniques of surgery, the need for packing after surgery is debatable…
- Conditions
- Epistaxis, Nasal Obstruction, Pain
- Trial name
- NCT00793117
- Testing
- packing
- Where
- Iran
- Volunteers
- 66 people
- Sponsor
- Tehran University of Medical Sciences
Nasotracheal Intubation, Nasal Bleeding
Nasotracheal Intubation Over a Bougie
The purpose of this study is to determine whether nasal intubation over a bougie placed via a nasal trumpet will decrease nasal trauma when compared to the conventional technique of blind nasal endotracheal tube passage.
- Trial name
- NCT03003455
- Testing
- Nasotracheal intubation over a bougie, Conventional Nasotracheal Intubation
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Endoscopic Sinus Surgery, Nasal Polyps
Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgery
The purpose of this study is to compare the effects of Oxymetazoline and Epinephrine (which are 2 different nasal decongestants both of which are routinely used before sinus surgery) on blood loss and the surgeon's view of the…
- Trial name
- NCT03228914
- Testing
- Oxymetazoline, Epinephrine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston