Clinical trials: Nutrition Processes
Post Intensive Care Unit Syndrome, Critical Illness
Improving Recovery After Critical Illness
Rationale: Survival rates of patients with critical illness have increased due to improved facilities and treatment methods in the intensive care unit (ICU).
- Conditions
- Post Intensive Care Unit Syndrome, Critical Illness, Malnutrition, Muscle Weakness
- Trial name
- IMPROVE (NCT05182086)
- Testing
- Group physical therapy and dietary improvements
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Frisius Medisch Centrum
Critical Illness, Pediatric Intensive Care
Continuous vs Bolus Protein (Protein Regimen Outcomes) in Critically Ill Children (Kids In Distress)
The goal of this intervention study is to evaluate the difference in nutrition status markers (weight and muscle mass) when giving dietary protein by continuous or bolus delivery in critically ill children ages 1-11y.
- Conditions
- Critical Illness, Pediatric Intensive Care, Enteral Nutrition Therapy, Dietary Protein
- Trial name
- PRO-KID (NCT06721923)
- Testing
- Dietary protein
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of British Columbia
Growth Disorders, Dietary Exposure
Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns
This single-center, randomized controlled pilot study aims to evaluate the efficacy of TruHeight Growth Protein Shake on improving growth patterns in children aged 4-17 years.
- Conditions
- Growth Disorders, Dietary Exposure, Child Development, Bone Development Abnormal
- Trial name
- NCT06329388
- Testing
- TruHeight Growth Protein Shake
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- TruHeight Vitamins
Critical Illness
CONTINUation of Enteral Nutrition Prior to Extubation Compared to Standard Care
Critically ill patients admitted to the Intensive Care Unit (ICU) often need to be connected to a breathing machine (ventilator) and are unable to eat.
- Trial name
- CONTINUE (NCT06382727)
- Testing
- EN will be continued up to extubation (EN will not be withheld prior to extubation)
- Where
- 3 sites in Australia
- Volunteers
- 60 people
- Sponsor
- Emma Ridley
Left Ventricular Dysfunction, Myocardial Infarction
St. Vincent's Screening To Prevent Heart Failure Study
The STOP-HF study is a prospective, randomized, controlled trial recruiting asymptomatic individuals with risk factors for left ventricular dysfunction from 50 primary care clinics in Dublin and south east Ireland.
- Conditions
- Left Ventricular Dysfunction, Myocardial Infarction, Hypertension, Diabetes
- Trial name
- STOP-HF (NCT00921960)
- Testing
- Intervention Care
- Where
- Ireland
- Volunteers
- 1,378 people
- Sponsor
- St Vincent's University Hospital, Ireland
Chronic Kidney Disease, Periodontitis
Chronic Kidney Disease Associated Diet
The goal of this observational study is to investigate the relationship between chronic kidney disease (CKD) and periodontitis, and to evaluate the potential mediating role of dietary inflammatory potential, measured by the…
- Conditions
- Chronic Kidney Disease, Periodontitis, Diet, Food and Nutrition
- Trial name
- NCT07427069
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Obesity, Morbid Obesity
Lifestyle Intervention Feasibility for Arrhythmia and Symptoms With Intermittent Fasting (LIFE AS IF)
BACKGROUND AND RATIONALE Two out of three Americans are overweight and obesity is associated with hypertension, sleep apnea, atrial fibrillation.
- Conditions
- Obesity, Morbid Obesity, Diabetes Mellitus, Type 2, Atrial Fibrillation
- Trial name
- LIFE AS IF (NCT04090840)
- Testing
- Intermittent Fasting
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Chicago
Cardiovascular Diseases, Cerebrovascular Accident
Homocyst(e)Ine, Vitamin Status, and CVD Risk
To test the hypotheses that the risk of myocardial infarction and/or stroke is associated with elevated plasma levels of homocysteine, and low plasma levels of folate, vitamins B12 and B6.
- Conditions
- Cardiovascular Diseases, Cerebrovascular Accident, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00005482
- Sponsor
- University of Washington
Metabolism Disorder, Adiposity
Effect of Exercise and Omega-3 on Metabolic Health in Elderly
The aim of this project is to investigate in elderly women, the effect of combined aerobic and resistive training and concomitant supplementation with omega-3 fatty acids on adipogenesis, metabolic functions and pro-inflammatory…
- Conditions
- Metabolism Disorder, Adiposity, Inflammatory Response
- Trial name
- EXODYA (NCT03386461)
- Testing
- Exercise training, omega 3 supplementation
- Where
- Czechia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Necrotizing Enterocolitis, Sepsis
Lactulose Supplementation in Premature Infants
A pilot study to test the safety of use of lactulose in preterm infants and to preliminary assess the hypothesis that lactulose would support the early growth of Lactobacilli in the stools of premature infants and possibly would…
- Trial name
- NCT00616876
- Testing
- Lactulose, Dextrose
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Bnai Zion Medical Center
Malnutrition, Child
Hens Hatching Hope
The study is a prospective community-cluster non-randomized trial that will evaluate the effectiveness of a program that will provide 30-day egg vouchers to mothers of 6 to 24 month-old children living in rural areas of Intibucá…
- Trial name
- NCT04721197
- Testing
- Egg vouchers, Standard of Care
- Where
- Honduras
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University
Hyperoxaluria (Disorder)
Oxalate Excretion Profile in Patients With a Heterozygous Mutation of the AGXT (Alanine-glyoxylate Aminotransferase) Gene
Primary hyperoxaluria type I (PH1) is a rare genetic disorder responsible for severe lithiasis leading to progressive deterioration of renal function and end-stage renal failure.
- Trial name
- HETEROX (NCT06283082)
- Testing
- Lithiasis assessment
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Hospices Civils de Lyon
Head and Neck Cancer, Intraoperative Complications
Coagulation and Vitamin K in Head and Neck Microvascular Free Flap Surgery
For patients with large head and neck tumors the recommended treatment, in many cases, is a combination of extensive surgery and postoperative radiotherapy.
- Conditions
- Head and Neck Cancer, Intraoperative Complications, Coagulation Disorder, Blood, Vitamin K Deficiency
- Trial name
- MVL-COAG (NCT04517461)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Skane
Stroke, Acute, Malnutrition
The Effect of Nutrition Counseling on Nutritional Status in Stroke Patients
The purpose of this study is to investigate the effect of intensive nutrition counseling on nutritional status and functional recovery in stroke patients over the age of 65, compared to standard nutrition counseling.
- Conditions
- Stroke, Acute, Malnutrition, Old Age; Debility
- Trial name
- NCT06208969
- Testing
- intensive nutrition counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Ege University
Weight Loss, Obesity
A Grapefruit Feeding Trial in Healthy, Overweight Adults
Folklore has suggested that consuming grapefruit may promote weight control. Sparse data exist to support this hypothesis, though there is some evidence of health promotional effects regarding blood pressure and lipid profiles.
- Conditions
- Weight Loss, Obesity, Cardiovascular Risk Factors
- Trial name
- NCT01452841
- Testing
- Grapefruit, Control
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFpEF)
Tirzepatide on Atrial Fibrillation Recurrence After Catheter Ablation in Patients With Obesity and HFpEF
This multicenter, randomized, open-label, blinded-endpoint trial evaluates whether weekly subcutaneous tirzepatide for 12 months reduces atrial fibrillation (AF) recurrence after catheter ablation in adults with obesity and heart…
- Conditions
- Atrial Fibrillation, Heart Failure With Preserved Ejection Fraction (HFpEF), Tirzepatide
- Trial name
- TEAR-AF-HFpEF (NCT07630454)
- Testing
- Tirzepatide, Structured Lifestyle Intervention
- Where
- China
- Volunteers
- 602 people
- Sponsor
- Yunlong Wang
Malnutrition, Critical Illness
Assessment of Nutritional Status in Critically Ill Children in PICU
This prospective cohort study aims to assess the nutritional status of critically ill children aged 1 month to 5 years admitted to the pediatric intensive care unit using a comprehensive ABCD approach including anthropometric…
- Trial name
- NCT07830966
- Volunteers
- 103 people
- Sponsor
- Assiut University
Diabetes, Heart Diseases
Personalised Responses to Dietary Composition Trial
The foods we eat - our diet - can affect whether we develop diseases during our lives, such as diabetes or heart disease. This is because the amount and types of foods we eat can affect our weight, and because different foods are…
- Conditions
- Diabetes, Heart Diseases, Diet Habit, Diet Modification
- Trial name
- PREDICT (NCT03479866)
- Testing
- Dietary intervention
- Where
- United Kingdom
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Vitamin A Deficiency, Maternal Mortality
Impact of Maternal Vitamin A or Beta-Carotene Supplementation on Maternal and Infant Mortality in Bangladesh
The purpose of this trial is to determine whether providing women with a weekly oral supplement of vitamin A, either preformed or as beta-carotene, at a dosage equivalent to a recommended intake from early pregnancy through three…
- Conditions
- Vitamin A Deficiency, Maternal Mortality, Infant Mortality
- Trial name
- NCT00198822
- Testing
- Vitamin A or Beta-Carotene Supplements
- Where
- 3 sites in United States, Bangladesh
- Volunteers
- 59,666 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Eating Behavior, Obesity
Effect of mCPP on Cognitive Control, Appetite, and Neural Responses
Previous studies have reported that the 5-HT2C receptor agonist meta-chlorophenylpiperazine (mCPP) decreases appetite and food intake in humans1-3.
- Trial name
- mCPP (NCT03962829)
- Testing
- mCPP
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
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