Clinical trials: Nutrition Sciences
Cholestasis
Ursodiol for Treating Parenteral Nutrition Associated Cholestasis in Neonates
The purpose of this study is to determine whether ursodiol is effective in the treatment of parenteral nutrition associated cholestasis in neonates.
- Trial name
- URSONEONAT (NCT00846963)
- Testing
- Ursodiol
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Ibrahim Mohamed
Diabetes Mellitus, Type 2, Overweight
Combined Bariatric Surgery and Pancreas After Kidney Transplantation for Type II Diabetics
The goal of this clinical trial is to evaluate the effectiveness of sleeve gastrectomy combined with pancreas after kidney (PAK) transplantation as a means of achieving normoglycemia, insulin independence, reduced insulin…
- Trial name
- ComB-PAK (NCT05576116)
- Testing
- Sleeve Gastrectomy AND Pancreas after Kidney Transplantation (Staggered Approach), Combined Sleeve Gastrectomy and Pancreas transplantation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Hemodialysis-Induced Symptom
Factors Influencing Hemoglobin Variability and Its Association With Mortality in Hemodialysis Patients
The aim of the study is to investigate the factors influencing hemoglobin variability with inflammatory and nutritional parameters and its associations with all-cause mortality among hemodialysis patients.
- Trial name
- NCT03454906
- Volunteers
- 169 people
- Sponsor
- Baskent University
Obesity, Overweight
Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)
The purpose of this study is to determine the effects of NB relative to placebo on major adverse cardiovascular events (MACE) such as cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke in overweight and…
- Trial name
- NCT01601704
- Testing
- NB32, PBO, Weight Management Program
- Where
- 224 sites in United States
- Volunteers
- 8,910 people
- Sponsor
- Orexigen Therapeutics, Inc
Adiposity
Vitamin D and Omega-3 Adiposity Trial (VITAL Adiposity)
The VITamin D and OmegA-3 TriaL (VITAL; NCT 01169259) is a randomized clinical trial in 20,000 U.S. men and women investigating whether taking daily dietary supplements of vitamin D3 (2000 IU) or omega-3 fatty acids (1 gram of…
- Trial name
- VITAL (NCT01785004)
- Testing
- Vitamin D3 (cholecalciferol), 2000 IU per day, omega-3 fatty acids (fish oil)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cancer, Cachexia; Cancer
Improvement of Neuromuscular Function, Fatigue and Quality of Life by Optimizing Muscle Building and Nutrition in Colorectal Cancer: a Pilot Study
This study is based on the assumption that muscle strength and muscle mass will be better preserved in an "intervention" group with specific management combining retraining and nutritional monitoring compared to the "no…
- Trial name
- ColCanter (NCT04136249)
- Testing
- Over physical activity
- Where
- France
- Volunteers
- 30 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Fish Oils, Perfusion; Complications
Effects of Omega-3 Fish Oil Fat Emulsion on Rehabilitation and Immune Function After Radical Surgery Combined With Intraperitoneal Hyperthermic Infusion Chemotherapy in Patients With Locally Advanced Gastric Cancer
The purpose of this study was to investigate the effects of omega-3 fish oil fat emulsion on peripheral blood C-reactive protein, total lymphocyte count, plasma albumin and immune function after radical surgery combined with…
- Conditions
- Fish Oils, Perfusion; Complications, Stomach Neoplasms, Nutrition Aspect of Cancer
- Trial name
- NCT06047158
- Testing
- Omega-3 fish oil fat emulsion
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Obesity, Overweight
A Safety and Efficacy Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects
The purpose of this study is to determine whether the combination of naltrexone SR and bupropion SR is safe and effective in the treatment of obesity.
- Trial name
- NCT00567255
- Testing
- Naltrexone SR 32 mg/bupropion SR 360 mg/day, Ancillary therapy
- Where
- 36 sites in United States
- Volunteers
- 1,496 people
- Sponsor
- Orexigen Therapeutics, Inc
Prader-Willi Syndrome
GH in Adults With PWS, Effect on Hypotonia Evaluated by Functional MRI, Relationship With Strength and Body Composition
Prader-Willi syndrome (PWS) is a genetic disorder associated with growth hormone (GH) deficiency, central hypotonia and hyperphagia that leads to life-threatening obesity.
- Trial name
- NCT03616509
- Testing
- Growth hormone
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Malnutrition
The Tany Vao Project.
The TANY VAO project pilot study aimed to create a circular and sustainable model with a multidimensional and multidisciplinary approach to improve the health conditions of Madagascar's population living in rural areas.
- Trial name
- NCT06195098
- Testing
- Nutritional educational intervention
- Where
- Italy
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Obesity, Dysbioses
Use of Probiotic Yogurt in Obese Women
This study aimed to examine the effects of using probiotic yogurt on body components (body weight, height, etc.) and digestive system (distention, gas, etc.) in obesity (obese women), which is an important public health problem…
- Trial name
- NCT05364814
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Yuksek Ihtisas University
Aging
Study to Design a Precision Nutrition Strategy At a Group Level in the Elderly
From a public health point of view, personalized nutritional recommendations, at the individual level, are difficult to achieve in the short-medium term, especially in population segments with less purchasing power.
- Trial name
- NUTRIMET (NCT05566938)
- Testing
- Tailored nutritional recommendations for each metabotype
- Where
- Spain
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Obesity & Overweight
IGOB131 As A GLP-1 Modulator For Metabolic Disorders In Adults With Obesity
This clinical trial will investigate the effect of standardized Irvingia gabonensis extract (IGOB131) on GLP-1 dynamics, DPP-4 activity, metabolic parameters, and inflammatory markers in adults with obesity.
- Trial name
- NCT07884058
- Testing
- IGOB131, Dextrin
- Volunteers
- 80 people
- Sponsor
- University of Yaounde 1
Type 2 Diabetes, Overweight
The Effect of Semaglutide on Disordered Eating Behaviour in Type 2 Diabetic Patients
The aim of this study is to evaluate the effect of glucagon-like peptide-1 (GLP-1) receptor agonist semaglutide on disordered eating behaviour in patients with overweight and type 2 diabetes.
- Conditions
- Type 2 Diabetes, Overweight, Disordered Eating Behaviors
- Trial name
- NCT06243536
- Testing
- Semaglutide, standard of care
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Sestre Milosrdnice
Pregnancy
The Effect of Under-nutrition on the Human Microbiota
The purpose of this study is to determine whether a difference exists in the gut, oral, vaginal and human milk microbiome of under-nourished pregnant women as compared to healthy and obese pregnant women.
- Trial name
- NCT02021799
- Testing
- Moringa and Lactobacillus rhamnosus GR-1
- Where
- Tanzania
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Homeostasis, Metabolism and Nutrition Disorder
Energy Metabolism Profiles Over Weight-loss and Eating Responses
This is an exploratory controlled before-after study, which involves 112 participants, of whom 28 are with normal weight and 84 are overweight or obese.
- Conditions
- Homeostasis, Metabolism and Nutrition Disorder, Healthy, Obesity
- Trial name
- NCT05785221
- Testing
- General lifestyle and nutritional education, Personalized nutritional and lifestyle weight reduction intervention
- Where
- China
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Sciences
Aging, Menopause
Gonadal Hormone, Gonadotropin and Cardiovascular Events
Deficiency in gonadal hormone has been considered to play a role in ageing related increased incidence of cardiovascular events. But the mechanism has not been fully elucidated.
- Trial name
- NCT02810821
- Where
- China
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Shandong Provincial Hospital
Food Insecurity, Overweight
Weekly Family Food Packages: Food is Medicine
The specific aims and objectives of this proposal are to: 1. Evaluate a food pantry's weekly food distribution impact on behavioral, social and health outcomes in families. 2.
- Conditions
- Food Insecurity, Overweight, Obesity, Cardiometabolic Syndrome
- Trial name
- NCT05640414
- Testing
- Weekly Family Food Packages, Family Health Group Sessions
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Massachusetts General Hospital
Obesity
Evaluation of Long Term Safety of Tesofensine in Patients With Obesity
Purpose of the study is to evaluate the long term safety of tesofensine in obese patients
- Trial name
- NCT00481104
- Testing
- Tesofensine
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- NeuroSearch A/S
Obesity
STAGES Trial: Study of Adiposity, Growth and Endocrine Stages
The investigators propose to conduct a cross-sectional study of 60 participants who are 18-30 years of age to undergo research PET/CT.
- Trial name
- STAGES (NCT01460784)
- Where
- United States
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- University of Utah
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