Clinical trials: Nutritional Supplement
Multiple Sclerosis
Dietary Supplement of Curcumin in Subjects With Active Relapsing Multiple Sclerosis Treated With Subcutaneous Interferon Beta 1a
This is a prospective, monocentric, double blind, placebo controlled, two arm study. Curcumin is derived from the rhizomes of the plant Curcuma longa (common name, turmeric) belonging to the Zingiberaceae family found in South…
- Trial name
- CONTAIN (NCT01514370)
- Testing
- IFN beta 1a 44 mcg TIW, Curcumin
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Chemotherapeutic Agent Toxicity, Multiple Myeloma
Glutamine in Preventing Peripheral Neuropathy in Patients With Multiple Myeloma Receiving Bortezomib
This randomized phase II trial studies glutamine in preventing peripheral neuropathy in patients with multiple myeloma who are receiving bortezomib.
- Conditions
- Chemotherapeutic Agent Toxicity, Multiple Myeloma, Peripheral Neuropathy
- Trial name
- NCT01783522
- Testing
- glutamine, quality-of-life assessment
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Beth Faiman
Hyperinsulinism-Hyperammonemia Syndrome
Vitamin E Supplementation in Hyperinsulinism/Hyperammonemia Syndrome
Investigators will assess the tolerability of oral Vitamin E supplementation in subjects with congenital hyperinsulinism (HI) and hyperammonemia (HA) syndrome.
- Trial name
- NCT03797222
- Testing
- Vitamin E
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Elizabeth A Rosenfeld
Polycystic Ovary Syndrome
Vitamin D for the Treatment of Women With Polycystic Ovary Syndrome (PCOS)
The purpose of this study is to determine if vitamin D will improve insulin resistance, inflammation, and overall well-being in women with PCOS.
- Trial name
- NCT00907153
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Milton S. Hershey Medical Center
Progesterone Supplementation in Women Undergoing ART
Clinical Safety Study of the Progesterone Vaginal Ring in Women Undergoing Assisted Reproductive Technology Procedures
The purpose of the study is to assess the safety of Progesterone Vaginal Ring (PVR) in women undergoing fresh embryo transfer (ART).
- Trial name
- SARA (NCT03565211)
- Testing
- Progesterone vaginal ring
- Where
- 15 sites in United States
- Volunteers
- 352 people
- Sponsor
- Ferring Pharmaceuticals
Brain Concussion
BCAA Supplementation for Concussion
This study is a randomized, placebo-controlled, double-blinded, therapeutic exploratory clinical trial of branched chain amino acids (BCAA's) in the treatment of concussion.
- Trial name
- HIT_HEADS (NCT01860404)
- Testing
- Branched Chain Amino Acids
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's Hospital of Philadelphia
Multiple System Atrophy
Progression Rate of MSA Under EGCG Supplementation as Anti-Aggregation-Approach
MSA is a rapidly progressive disorder with an average survival time of about 7 years after the first clinical manifestation. No potent symptomatic treatment is currently available.
- Trial name
- PROMESA (NCT02008721)
- Testing
- EGCG as putative neuroprotective agent
- Where
- 12 sites in Germany
- Volunteers
- 92 people
- Sponsor
- Dr. Johannes Levin
Vitamin D Deficiency
Topical Delivery of Vitamin D3 as Vitamin D Supplementation
After obtaining the approval from the IRB of University of Dammam and informed consent from 550 healthy patients, with vitamin D deficiency and vitamin D insufficiency and deficiency were recruited.
- Trial name
- NCT02735200
- Testing
- Application of topical vitamin d3 (Top-D), Application of Aloe vera gel
- Where
- Saudi Arabia
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Pharmacokinetics
A Phased Clinical Trial of Dietary Supplemental Kava: Kava Pharmacokinetics
Kava is a dietary supplement on the US market and is experiencing a resurgence of its use. Its pharmacokinetic information, however, is lacking which is important for its future effective usage as a dietary supplement or…
- Trial name
- KavaPK (NCT03843502)
- Testing
- Kava Dietary Supplement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Heart Failure, Systolic
Nicotinamide Riboside in Systolic Heart Failure
Mitochondrial dysfunction has been implicated in heart failure (HF), and is associated with an imbalance in intracellular ratio of reduced nicotinamide-adenine dinucleotide (NADH) to oxidized nicotinamide-adenine dinucleotide…
- Trial name
- NCT03423342
- Testing
- nicotinamide riboside
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Washington
Cobalt Biokinetics, Safety of Cobalt Dietary Supplementation
90-Day Cobalt Supplementation Study to Investigate the Cobalt Body Burden in Ten Healthy Adult Volunteers
The purpose of this study is to investigate steady-state cobalt levels following dietary supplementation for 90 days with 1 mg cobalt/day (as cobalt chloride in solution) in healthy adult volunteers.
- Trial name
- NCT01990794
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cardno ChemRisk
Type 2 Diabetes
Anti-inflammatory Effects of the Fiber
This study will help elucidate the mechanism underlying the cardioprotective and anti-diabetes effect of dietary fiber by exploring a comprehensive set of inflammatory and oxidative stress markers, based on a contemporary…
- Trial name
- NCT02868788
- Testing
- dietary fiber, HFHC meal
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University at Buffalo
Attention Deficit Hyperactivity Disorder
Micronutrients for Attention-Deficit Hyperactivity Disorder in Youth (MADDY) Study
This proposed research will use randomized control trial (RCT) methodology and compare micronutrients with placebo in 135 children with ADHD.
- Trial name
- MADDY (NCT03252522)
- Testing
- Broad Spectrum Micronutrients; a 36-ingredient blend of vitamins, minerals, amino acids, and antioxidants
- Where
- 3 sites in United States, Canada
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Parkinson Disease, Parkinson Disease Dementia
Sing for Your Saunter - Dementia Supplement
Older adults, and particularly those with Parkinson disease (PD), may experience walking difficulties that negatively impact their daily function and quality of life.
- Trial name
- SFYS-D (NCT04518917)
- Testing
- Mentally Singing, Listening to music
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Washington University School of Medicine
Intrauterine Resuscitation
Intrapartum Maternal Oxygen Supplementation: Effects on the Mother and Neonate
Approximately 2/3 of laboring women receive supplemental oxygen (O2) in an attempt to reverse perceived fetal hypoxia on electronic fetal monitoring (EFM).
- Trial name
- O2P2 (NCT03581214)
- Testing
- No oxygen, Oxygen
- Where
- United States
- Volunteers
- 910 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity, Weight Loss
Utilizing Protein During Weight Loss to Impact Physical Function
This study will evaluate the effects of diet composition (i.e., amount of protein and carbohydrate) during a 6-month weight loss intervention and 12-months of follow-up on physical function, muscle mass, and weight loss…
- Conditions
- Obesity, Weight Loss, Diet Modification, Aging
- Trial name
- UPLIFT (NCT03074643)
- Testing
- Weight loss intervention months 0-6, Exercise intervention months 0-6, Carbohydrate supplement for months 0-6
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Wake Forest University Health Sciences
Sarcopenia
Carnitine Supplementation and Skeletal Muscle Function
Research project objectives The primary aim of the current research project is to use carnitine supplementation as the anti-inflammatory intervention for exploring the relationship between inflammation and associated with aging…
- Trial name
- NCT02692235
- Testing
- carnitine
- Where
- Poland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Sleep Disorders, Hypertension
Melatonin Supplements for Improving Sleep in Individuals With Hypertension
This study will evaluate the effectiveness of treatment with melatonin supplements in improving sleep in individuals with high blood pressure who are taking beta-blockers.
- Trial name
- NCT00238108
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Brigham and Women's Hospital
Critical Illness, Sepsis
Trial of Glutamine and Antioxidant Supplementation in Critically Ill Patients
The purpose of this study is to determine whether providing high dose glutamine and antioxidants to critically ill patients will be associated with improved survival.
- Conditions
- Critical Illness, Sepsis, Multiple Organ Failure
- Trial name
- REDOXS (NCT00133978)
- Testing
- Glutamine, Antioxidants, Glutamine + Antioxidants
- Where
- 34 sites in United States, Belgium and 3 more
- Volunteers
- 1,223 people
- Sponsor
- Daren K. Heyland
Diabetes Mellitus, Type 1, Hypoglycemia
Pilot Study of OMEGA-3 and Vitamin D in High-Dose in Type I Diabetic Patients
The investigator propose to test the safety and efficacy of a regimen that combines Omega-3 Fatty Acids and Vitamin D in a design that considers timing and duration of administration in relation to their effects and predicted…
- Conditions
- Diabetes Mellitus, Type 1, Hypoglycemia, Diabetes Mellitus, Diabetes, Autoimmune
- Trial name
- POSEIDON (NCT03406897)
- Testing
- Cholecalciferol, Omega 3 fatty acid
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Rodolfo Alejandro