Clinical trials: OCT Angiography
Spaceflight Associated Neuro-Ocular Syndrome, SANS
The Eye in Orbit: UCF Adaption
The goal of this study is to understand the impact of space travel on the eyes. Space flight impacts numerous aspects of ocular anatomy and physiology.
- Trial name
- NCT06092359
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Central Florida
Myopia, Perfusion; Complications
OCTA Analysis of Macular and Papillary Perfusion After Refractive Surgery in Myopes
Refractive surgery for correction of myopia is very common nowadays. However, various refractive techniques may be associated with increase in the IOP, especially during flap creation.
- Trial name
- NCT04424069
- Testing
- Refractive surgery
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Diabetic Vitreous Hemorrhage, Tractional Retinal Detachment
Assessment of Retinal Vascular Changes With and Without ILM Peeling in Diabetic Vitrectomy Using OCT-A.
Tractional retinal detachment (TRD) that involves the macula and non-clearing vitreous hemorrhage are the main causes of permanent vision loss in patients with diabetic retinopathy and requires prompt surgical intervention.
- Trial name
- NCT05739539
- Testing
- optical coherence tomography angiography, spectral domain optical coherence tomography
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Kasr El Aini Hospital
Central Serous Chorioretinopathy
Optical Coherence Tomography Angiography (OCT-A) and Central Serous Chorioretinopathy (CSC)
Optical Coherence Tomography Angiography (OCT-A) is a noninvasive imaging technique that allows one to see blood vessels in the retina.
- Trial name
- OPACITY (NCT03950089)
- Testing
- Optical Coherence Tomography Angiography (OCT-A)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Macular Degeneration Exudative Eye Left, Macular Degeneration Exudative Eye Right
OCTA (Optical Coherence Angiography Tomography) Versus Structural OCT(Optical Coherence Tomography) in Neovascular AMD (Age Macular Degeneration)
The objective is to find if there is a relationship between the Fractal Dimension, the gap, vascular density (VD), the surface, the span ratio and the status of the choroidal neovessels to adjust the interval between 2…
- Trial name
- QUAOBARE (NCT03939195)
- Testing
- Follow-up
- Where
- 3 sites in France
- Volunteers
- 130 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Coronary Artery Disease, Stent Restenosis
Intracoronary Optical Coherence Tomography Guidance Vs. Angiography Only Guidance for Treatment of Coronary In-stent Restenosis
Although advances in drug-eluting stents (DES) have substantially reduced the risk of coronary in-stent restenosis (ISR) and the need for target lesion revascularisation (TLR), ISR persists.
- Conditions
- Coronary Artery Disease, Stent Restenosis, STENT
- Trial name
- INSIDE OCT (NCT06779110)
- Testing
- Percutaneous Coronary Intervention
- Where
- 12 sites in Italy
- Volunteers
- 360 people
- Sponsor
- San Luigi Gonzaga Hospital
Pituitary Adenoma
OCT-angiography as a Pronostic Marker for Visual Impairment in Patients Undergoing Neurosurgery for Compressive Macroadenoma : a Prospective Study.
The aim of the study is to assess accurancy of OCT angiography as a pronostic marker for patients undergoing neurosurgery for compressiver macroadenoma as compared with visual acuity, visual field and OCT.
- Trial name
- FIRST (NCT04074642)
- Testing
- Neurosurgery
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Coronary Artery Disease
OCT- Versus Angiography-guided Paclitaxel Drug-Coated Balloon Angioplasty in De Novo Coronary Artery
OCT allows precise evaluation of intimal injury after lesion preparation and may improve the acute results and long-term outcomes after paclitaxel drug-coated balloon angioplasty.
- Trial name
- NCT04276389
- Testing
- OCT-guided paclitaxel drug-coated balloon angioplasty, Angiography-guided paclitaxel drug-coated balloon angioplasty
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Angioplasty, Restenosis
Optimal Strategy to Correct Stent underexpAnsion in Resistant Lesions
Percutaneous coronary intervention (PCI) for in-stent restenosis (ISR) accounts for 5-10% of PCI. ISR may be linked to mechanical complications mainly under-expansion (UE), neointimal hyperplasia and/or neoatherosclerosis.
- Conditions
- Coronary Angioplasty, Restenosis, Lithotripsy, Restenosis of Coronary Artery Stent
- Trial name
- OSCAR (NCT07316504)
- Testing
- Intravascular lithotripsy, Balloon
- Where
- 2 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
SLE (Systemic Lupus)
Posterior Segment Evaluation of Patients With SLE Using OCT and OCTA
Aim of The Study To evaluate different structural retinal changes using OCT and OCT-A in patients with SLE ; newly diagnosed patients and patients on treatment and compare parameters with normal subjects
- Trial name
- NCT04866615
- Testing
- Optvue OCT
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Minia University
Healthy
Semi-manual Vessel Density Analysis on Optical Coherence Tomography Angiography Images of Healthy Adults
Purpose of the study is to examine the vessel density of healthy adults' optical coherence tomography angiography images with two semi-manual methods and an automated quantification program.
- Trial name
- NCT03590899
- Testing
- Optical coherence tomography angiography (Zeiss Cirrus HD OCT 5000 AngioPlex)
- Where
- Hungary
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Pseudophakic Cystoid Macular Edema
Optical Coherence Tomography Angiography and Pseudophakic Cystoid Edema
This study evaluates the retinal vascular features in macula and papillary regions in patients affected by pseudophakic cystoid edema using optical coherence tomography angiography
- Trial name
- NCT05117411
- Testing
- OCTA and pseudophakin cystoid edema
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federico II University
Diabetic Macular Edema
Follow up of Diabetic Macular Edema Treated by Aflibercept (Eylea®) With OCT-Angiography
This is a non-interventional, longitudinal, retrospective and prospective, non-controlled, single arm study in naive or non-naive patients with diabetic macular edema for which aflibercept (EYLEA®) therapy is indicated.
- Trial name
- DOCTA (NCT03783832)
- Testing
- OCT ANGIOGRAPHY DATA
- Where
- 6 sites in France
- Volunteers
- 48 people
- Sponsor
- Aquitania Opthalmologica
Choroid, Retina
Effect of Different Intensities of Repeated Low-Level Red-Light Therapy on Choroidal and Retinal Blood Flow Among Adults
The purpose of this clinical trial is to evaluate the effect of different intensities of repeated low-level red-light (RLRL) therapy on the choroidal and retinal blood flow among adults.
- Trial name
- NCT05747742
- Testing
- RLRL device
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Second People's Hospital of Foshan
Cardiac Allograft Vasculopathy
Optical Coherence Tomography (OCT) to Evaluate Cardiac Allograft Vasculopathy (CAV) in Patient's Post Heart Transplant
Cardiac allograft vasculopathy (CAV) is a unique form of accelerated plaque formation seen in the coronary arteries of patients who have received heart transplantation.
- Trial name
- OCTCAV (NCT01403142)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Columbia University
Colorectal Cancer
Modifications in Retinal Microvascularization With Targeted Anti-angiogenic Therapy in Colorectal Cancer
Retinal microvascularization can provide important informations to systemic vascular phenomena. The non-invasive quantitative description of the retinal vascularization is now possible by performing OCT-angiography and their…
- Trial name
- VOCANGIO (NCT04952688)
- Testing
- OCT- Angiographie
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Georges Francois Leclerc
COVID-19 Pandemic
Retinal and Choroidal Microvascular Parameters in School-age Children in a COVID-19 Infection Pandemic Peak in China
We designed this study to examine whether COVID-19 infection could lead to retinal and choroidal microvascular involvement in school-age children (6-18 years) in a pandemic peak in China.
- Trial name
- NCT05952466
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Guangzhou First People's Hospital
Epiretinal Membrane of Both Eyes
Optical Coherence Tomography Angiography (OCTA) Changes in Patients With Epiretinal Membranes (ERM) With and Without Peeling of the Internal Limiting Membrane (ILM)
Main objective The objective is to compare two surgical options in vitrectomies for epiretinal membranes using parameters of optical coherence tomography angiography.
- Trial name
- NCT05287009
- Testing
- ILM nonpeeling, ILM peeling
- Where
- Austria
- Volunteers
- 51 people
- Sponsor
- Medical University of Graz
Behçet's Disease
Relation Between Nail Fold Capillaroscopy, Optical Coherence Tomography Angiography, and Femoral Vein Wall Thickness in Behçet's Disease Relation Between Nail Fold Capillaroscopy, Optical Coherence Tomography Angiography, and Femoral Vein Wall Thickness in Behçet's Disease
Relation between Nail Fold Capillaroscopy, Optical Coherence Tomography Angiography, and Femoral Vein Wall Thickness in Behçet's Disease
- Trial name
- NCT06296004
- Testing
- Nail Fold Capillaroscopy, Optical Coherence Tomography Angiography, and Femoral Vein Wall Thickness by U.S
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetic Retinopathy, Periodontitis
Periodontitis Severity in Patients With Diabetic Retinopathy
The aim of this observational study is to investigate the relationship between periodontal disease severity and retinal layer thickness in patients diagnosed with diabetic retinopathy (DR), using optical coherence tomography…
- Trial name
- NCT07137013
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital