Clinical trials: OSAS
Obstructive Sleep Apnea
Acoustic OSA Prediction During Wakefulness and Monitoring During Sleep
The purpose of this study is to investigate the feasibility of sound analysis for: a) sleep apnea detection both during wakefulness and sleep, and b) flow-sound relationship during both wakefulness and sleep in patients and…
- Trial name
- NCT04112927
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obstructive Sleep Apnea
Effect of a Very Low Calorie and Low Calorie Diet on Moderate to Severe Obstructive Sleep Apnea in Obese Adults
The purpose of this study is to test the effectiveness of two different weight loss diets on obstructive sleep apnea (OSA) severity.
- Trial name
- NCT02251574
- Testing
- Low Calorie Diet, Very Low Calorie Diet, Standard Care
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Obstructive Sleep Apnea
Inorganic Nitrate and OSA
The main purpose of this study is to determine if acute beetroot juice supplementation reduces peripheral chemoreflex sensitivity in patients with obstructive sleep apnea.
- Trial name
- NCT03930563
- Testing
- Pre-beetroot juice supplementation, Post-beetroot juice supplementation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Obstructive Sleep Apnea
Trial of Auto Continuous Positive Airway Pressure (CPAP)
Background: In patients with obstructive sleep apnea, automatic continuous positive airway pressure machines (autoCPAP) are said to be capable of identifying various breathing abnormalities during sleep and to correct them by…
- Trial name
- NCT01064258
- Testing
- CPAP, autoCPAP
- Where
- Belgium
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Obstructive Sleep Apnea
Validation of the Stardust Cardio-Respiratory Recorder
Introduction: The full night polysomnography (PSG) in sleep lab is the gold standard to Obstructive Sleep Apnea (OSA) diagnosis.
- Trial name
- Stardust (NCT00466011)
- Where
- 2 sites in Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Obstructive Sleep Apnea
Functional Capacity in Obstructive Sleep Apnea
Obstructive sleep apnea syndrome (OSAS) is a condition characterized by a deterioration in respiratory function and an increase in the activity of accessory respiratory muscles.
- Trial name
- NCT07913139
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Obstructive Sleep Apnea
Sodium-Restricted Diet and Diuretic in the Treatment of Severe Sleep Apnea
This study evaluates the intervention of the 1) sodium-restricted diet, or 2) diuretic, or 3) placebo pill in the treatment of obstructive sleep apnea in adults.
- Trial name
- DESALT (NCT01945801)
- Testing
- Lasilactone, Sodium-Restricted Diet
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Obstructive Sleep Apnea
Aspirin Resistance in OSA Patients
Obstructive Sleep Apnea (OSA) patients are at increased risk of major cardiovascular events, so many patients take aspirin for prevention.
- Trial name
- NCT03930875
- Testing
- Aspirin Resistance testing
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Danbury Hospital
Obstructive Sleep Apnea
Skiin-PSG Sleep Apnea
The goal of this observational study is to develop new algorithms to detect apnea and/or hypopnea to provide additional insights to Skiin users and to their circle of care to validate and/or improve the current algorithms of the…
- Trial name
- NCT06247878
- Testing
- Skiin underwear chest band
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Myant Medical Corp.
Sleep Disordered Breathing, Obstructive Sleep Apnea
An Investigation to Test a Prototype Nasal Mask in the Home Setting
This investigation is a prospective non-blinded and non-randomized clinical investigation. This investigation is to test the interpretation of user instructions of a prototype nasal mask on participants.
- Trial name
- NCT03752580
- Testing
- User Instructions of novel nasal mask
- Where
- New Zealand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fisher and Paykel Healthcare
Obstructive Sleep Apnea, Breathing, Sleep-Disordered
Cheeks Appearance as a Novel Predictor of Obstructive Sleep Apnea The CASA Score Study
Cheeks appearance is a screening tool developed based on cheeks observation to identify volume, flaccidity or both to predict people with probable obstructive sleep apnea.
- Conditions
- Obstructive Sleep Apnea, Breathing, Sleep-Disordered, Muscle Weakness, Muscle Disorder
- Trial name
- CASA (NCT04980586)
- Testing
- CASA score protocol to Non-obstructive sleep apnea Group, CASA score protocol to Mild obstructive sleep apnea Group, CASA score protocol to Moderate obstructive sleep apnea Group
- Where
- Brazil
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hypertension Secondary
Kynurenine/Tryptophan Ratio in Hypertension Associated to Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) is an independent risk factor for hypertension (HTN) and the most common cause of resistant HTN. The mechanisms underlying OSA-associated HTN are not completely understood.
- Trial name
- KYNTOSA (NCT04646902)
- Where
- 5 sites in Portugal
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Obstructive Sleep Apnea, Sleep Quality
Physical Activity, Sleep Quality, and Respiratory Function in Obstructive Sleep Apnea
Although exercise and physical activity have shown beneficial effects in individuals with obstructive sleep apnea (OSA), evidence regarding the effects of daily physical activity habits on sleep quality and respiratory parameters…
- Conditions
- Obstructive Sleep Apnea, Sleep Quality, Respiratory Function
- Trial name
- NCT07889154
- Testing
- Physical Activity Education
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medipol University
Obstructive Sleep Apnea Syndrome, Polycystic Ovary Syndrome
Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents
Polycystic ovary syndrome (PCOS) is one of the most common disease caused by hormonal imbalance and is also associated with overweight and obesity. It affects 5-10% of adolescent girls and women capable of having children.
- Conditions
- Obstructive Sleep Apnea Syndrome, Polycystic Ovary Syndrome, Sleep Apnea
- Trial name
- NCT01840618
- Testing
- Nasal Continuous positive airway pressure (CPAP)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
OSA, Heart Failure
Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized Cardiac Patients
The purpose of this study is to determine whether early diagnosis of obstructive sleep apnea and initiation of and adherence to CPAP therapy in hospitalized cardiac patients would impact 30-day hospital readmission rates.
- Conditions
- OSA, Heart Failure, Myocardial Infarction, Arrhythmia, Cardiac
- Trial name
- CV Readmit (NCT03647891)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Obstructive Sleep Apnea
Validation and Usability Study of the SleepView+ Home Sleep Testing System for the Evaluation of Moderate to Severe Obstructive Sleep Apnea.
The goal of this observational study is to characterize the performance of the SleepView+ home sleep test system for the evaluation of moderate to severe obstructuve sleep apnea (OSA) in adult and pediatric patients (ages 12 and…
- Trial name
- NCT07476313
- Testing
- SleepView+
- Where
- 4 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Beacon Biosignals
Sleep Apnea, Obstructive
BAY2586116 Nasal Spray and OSA Severity
This investigator-initiated study aims to determine the effects of BAY2586116 (a novel TASK channel blocker nasal spray) on sleep apnoea severity and the potential influence of route of breathing.
- Trial name
- NCT05527457
- Testing
- BAY2586116
- Where
- Australia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Flinders University
Obstructive Sleep Apnea Syndrome, Obesity
Portable Monitoring Device for the Diagnosis of Sleep Apnea in Obese Patients
Introduction The portable monitoring system (PMS) recording of cardiopulmonary parameters (level III of ASDA) has been validated in subjects with high probability of Obstructive Sleep Apnea (OSA) without comorbidities.
- Trial name
- NCT01455077
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Associacao Fundo de Incentivo a Psicofarmcologia
Obstructive Sleep Apnea
Study to Assess the Changes in Blood Clotting Factors and Blood Vessel Wall Function in Obstructive Sleep Apnea
Obstructive sleep apnea is a condition in which people have decreased breathing during their sleep. Untreated sleep apnea has been linked to increased risk for cardiovascular diseases.
- Trial name
- NCT00936481
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Sleep Apnea
Cerebrovascular Reactivity in Obstructive Sleep Apnea (OSA) Subjects
Obstructive sleep apnea (OSA) is a prevalent sleep breathing disorder in the general population in which recurrent collapse of the upper airway occurs during sleep.
- Trial name
- NCT01133717
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto