Clinical trials: OSAS
Obstructive Sleep Apnea
Treatment of Sleep Apnea With Oral Appliances
Obstructive sleep apnoea (OSA) is a serious and common disorder affecting one in twenty-five men and one in fifty women over the age of 30.
- Trial name
- NCT01209468
- Testing
- monobloc oral appliance, twinblock oral appliance
- Where
- Hong Kong
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Snoring, Obstructive Sleep Apnea
TranQuill™ Sling Snoreplasty for Snoring and Mild Obstructive Sleep Apnea:
The purpose of this study is to assess the safety and effectiveness of TranQuillTM Sling (a suture or thread used in surgery that is knotless) in snoreplasty (surgery procedure) for the treatment of snoring and mild OSA in adult…
- Trial name
- NCT02364518
- Testing
- Snoreplasty
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Obstructive Sleep Apnea Syndrome
Brain Oxygenation and Hemodynamics During Sleep in Obstructive Sleep Apnea Sufferers
The goal of this trial is to assess the performance of the OxiplexTS-an absolute near-infrared oximeter-as an instrument to measure brain oxygenation and hemodynamics in sleep medicine as well as in the broader field of…
- Trial name
- NIRS-OSAS (NCT00591591)
- Testing
- OxiplexTS
- Where
- 4 sites in United States
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- ISS, Inc.
Obstructive Sleep Apnea
Derivation and Validation of a Combination of BOSTON Score and DES-OSA Score for Selection of OSA Patients.
Derivation and Validation of a combination of BOSTON score and DES-OSA score to exclude OSA or to confirm OSA in patients.
- Trial name
- NCT03983564
- Testing
- Cutoff Validation
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Astes
Type 2 Diabetes, Obstructive Sleep Apnea (OSA)
Screening for Obstructive Sleep Apnea in High-risk Patients in a Danish Rural Population: A Pilot Feasibility Study
Background: Obstructive sleep apnea (OSA) is a sleep disorder characterized by recurrent collapse of the upper airway during sleep, resulting in intermittent hypoxia and fragmented sleep.
- Trial name
- NCT07778121
- Testing
- Home Sleep Apnea Test
- Where
- Denmark
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Pediatric Obstructive Sleep Apnea
Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea
Background: Obstructive sleep apnea (OSA) occurs when the blockage of the airway causes a person to stop breathing involuntarily for 10 seconds or more throughout the night during sleep.
- Trial name
- NCT05052216
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Obstructive Sleep Apnea, Overweight
Influence of Exercise, Weight Loss, and Exercise Plus Weight Loss on Sleep Apnea
Obstructive sleep apnea (OSA) is highly prevalent among Veterans, and is associated with significant mortality and multiple morbidities.
- Trial name
- NCT02721251
- Testing
- Exercise, Weight Loss, Exercise + Weight Loss
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sleep Apnea, Obstructive
Predictive Factors for Prescribing a Mandibular Advancement Device for the Treatment of Obstructive Sleep Apnea
This project evaluates the morphological predictive factors for prescribing a mandibular advancement device in the therapeutic approach of Obstructive sleep apnea (OSA).
- Trial name
- NCT05677620
- Testing
- Pharyngeal Computed Tomography, Drug-Induced Sleep Endoscopy (Propofol), Mandibular Advancement Device
- Where
- Portugal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Sleep Apnea, Obstructive, Fatty Liver
Prevalence of Non-alcoholic Fatty Liver Disease Among Non-obese Obstructive Sleep Apnea by Using Transient Elastography
Obstructive sleep apnea (OSA) and non-alcoholic fatty liver disease (NAFLD) are both common diseases related to metabolic diseases with potential cardiovascular consequences and liver complications respectively.
- Trial name
- NCT05351515
- Where
- Hong Kong
- Volunteers
- 861 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Obstructive Sleep Apnea, Sleep Position Trainer
RCT: Oral Appliance Therapy and Sleep Position Trainer in Patients With Position Dependant Obstructive Sleep Apnea
SUMMARY Rationale: Fifty-six percent of patients with Obstructive Sleep Apnea (OSA) are position dependent, defined as having an AHI, which is at least twice as high in supine sleeping position compared to the AHI during sleep in…
- Conditions
- Obstructive Sleep Apnea, Sleep Position Trainer, Oral Appliance Therapy
- Trial name
- POSA (NCT02045576)
- Testing
- sleep position trainer, Oral Appliance Therapy
- Where
- 2 sites in Netherlands
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
OSAHS, Gastrointestinal Endoscopy
Observation of Clinical Effect of New Oropharyngeal Airway in Patients With OSHAS During Painless Gastroenteroscopy
the(obstructivesleepapneahypoapneasyndromeOSAHS) is a kind of to sleep appear periodically in the process of syndrome characterized by partial or complete obstruction of upper respiratory tract.Patients with obstruction during…
- Conditions
- OSAHS, Gastrointestinal Endoscopy, Airway Complication of Anesthesia
- Trial name
- NCT06594380
- Testing
- Group using new oropharyngeal airway (experimental group), Endoscopic bite group (control group)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Ehlers-Danlos Syndrome, Obstructive Sleep Apnea
Obstructive Sleep Apnoea in Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome (EDS) is a clinically and genetically heterogeneous group of inherited connective tissue disorders characterized by joint hypermobility, skin hyperextensibility, and tissue fragility.
- Trial name
- OSA in EDS (NCT02435745)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Obstructive Sleep Apnea, Malocclusion
Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet
This research aims to provide pediatric patients with polysomnography (a sleep study) before and after orthodontic treatment to determine if the extraction of upper premolars for treating excessive overjet results in an increase…
- Trial name
- NCT04946201
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mohamed Bazina
Obstructive Sleep Apnea (OSA)
Biomarkers for Obstructive Sleep Apnea
The purpose of the study is to: recruit subjects with untreated sleep apnea; assess overnight changes in their blood and urine chemicals review the overnight changes in blood and urine chemicals after they have been treated for…
- Trial name
- BOSA (NCT00834509)
- Testing
- CPAP
- Where
- United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obstructive Sleep Apnea of Adult
Assessment of Pulmonary Artery Pressure and Right Sided Hemodynamics in Patients With OSA Before and After CPAP TTT
Obstructive sleep apnea (OSA) is a frequent sleep-related breathing disorder with an incidence of 5-20% in the middle-aged population in Europe and Northern America .
- Trial name
- NCT03276611
- Testing
- echocardiograghy
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
OSA
Impact of Intermittent Hypoxia on Neutrophil Extracellular Traps
This prospective observational study will enroll 60 moderate-to-severe OSA patients (AHI≧15/hour, 30 obese [BMI>=27] \& 30 non-obese [BMI<27]) and 40 age-, gender-, BMI-matched controls without OSA.
- Trial name
- NCT05485688
- Testing
- sleep apnea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Shift-Work Sleep Disorder, Insomnia
Fire Fighter Fatigue Management Program: Operation Healthy Sleep
Firefighters work some of the most demanding schedules known under highly stressful and demanding conditions. The need to work frequent extended shifts and long work weeks leads to acute and chronic partial sleep deprivation as…
- Conditions
- Shift-Work Sleep Disorder, Insomnia, Restless Leg Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT01988129
- Testing
- Sleep disorders education and screening
- Where
- United States
- Volunteers
- 1,189 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pediatric Sleep Apnea
Clinical Predictors of Pediatric OSAHS
The purpose of this study is to develop adequate and satisfactory tools using reliable clinical and physical factors in predicting pediatric obstructive sleep apnea/hypopnea syndrome (OSAHS) and allow greater access to…
- Trial name
- PEDOSA (NCT02627937)
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Obstructive Sleep Apnea
Sleep Apnea : Diagnosis and Monitoring
This prospective study aims to evaluate a new medical screening method to detect and discriminate sleep apnea-hypopnea events. A new device called ApneaBand will be tested to propose a new screening method facilitating the…
- Trial name
- ApneaBand (NCT03571477)
- Testing
- ApneaBand
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
Endothelial Dysfunction, Monocyte Activation, and Vasculopathy in Patients With Obstructive Sleep Apnea (OSA) and Effect of 6-month CPAP Treatment
This purpose of this study is to 1. Determine the change in endothelial dependent vascular reactivity and vascular properties 2. Determine the changes in monocytes activation 3. Determine the change in pro-inflammatory status 4.
- Conditions
- Sleep Apnea, Obstructive, Continuous Positive Airway Pressure, Endothelium, Inflammation
- Trial name
- NCT01312168
- Testing
- Therapeutic CPAP, Subtherapeutic CPAP
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital