Clinical trials: OSAS (Obstructive Sleep Apneas Syndrome)
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis
MASLD in Type 2 Diabetes in Primary Care - a Follow-up Study
The goal of this observational study is to understand how metabolic dysfunction-associated steatotic liver disease (MASLD) changes over time in individuals with type 2 diabetes who previously participated in the EPSONIP study.
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis, Advanced Fibrosis, Sarcopenia
- Trial name
- EPSOMIP2 (NCT07312136)
- Where
- Sweden
- Volunteers
- 317 people
- Sponsor
- Linkoeping University
Stroke, Sleep Apnea Syndrome (OSAS)
Sleep and Stroke Rehabilitation Study
The study aims to map sleep disorders and their impact on the ability to engage in an active daily life among people who have had a stroke, with particular focus on how sleep apnea can be identified.
- Conditions
- Stroke, Sleep Apnea Syndrome (OSAS), Insomnia, Excessive Daytime Sleepiness
- Trial name
- SnSRehabS (NCT07579871)
- Where
- Sweden
- Volunteers
- 226 people
- Sponsor
- Malin Eleonora av Kák Gustafsson, MD, PhD
OSAS (Obstructive Sleep Apneas Syndrome), DISE
The Use of Remimazolam Versus Dexmedetomidine for Patients Receiving Drug-Induced Sleep Endoscopy
This study seeks to compare the clinical efficacy and safety of the novel sedative Remimazolam with Dexmedetomidine in Drug-Induced Sleep Endoscopy (DISE), evaluating their performance in sedation depth stability, incidence of…
- Conditions
- OSAS (Obstructive Sleep Apneas Syndrome), DISE, Sedation
- Trial name
- NCT07459322
- Testing
- Remimazolam, Dexmedetomidine
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Fu Jen Catholic University Hospital
Obstructive Apnea, Diagnostic
Night-to-Night Variability of Novel Physiological Parameters in Home Sleep Apnea Testing
Obstructive sleep apnea (OSA) is usually diagnosed from a single night of home sleep apnea testing using the apnea-hypopnea index (AHI).
- Conditions
- Obstructive Apnea, Diagnostic, Sleep Apnea Syndrome (OSAS)
- Trial name
- N2N-OSA (NCT07555119)
- Where
- Switzerland
- Volunteers
- 192 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Sleep Apnea Syndrome (OSAS), Orthognathic Surgical Procedures
Splintless Versus Conventional Maxillomandibular Advancement Surgery for Obstructive Sleep Apnea
The goal of this clinical trial is to find out whether using a splintless surgical approach improves the accuracy of maxillomandibular advancement (MMA) surgery for treating obstructive sleep apnea (OSA) in adults.
- Conditions
- Sleep Apnea Syndrome (OSAS), Orthognathic Surgical Procedures, Sleep Apnea - Obstructive
- Trial name
- SvCMAS (NCT07598461)
- Testing
- Splintless MMA surgery, Splint MMA surgery
- Where
- Netherlands
- Volunteers
- 66 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Sleep Apnea Syndrome (OSAS), Central Sleep Apnea
Natural History of Central and Mixed Sleep Apneas Followed by Maxillomandibular Advancement for Obstructive Sleep Apnea
The goal of this observational prospective cohort study is to learn about the natural course of central and mixed sleep apneas that develop after maxillomandibular advancement (MMA) surgery for obstructive sleep apnea (OSA) in…
- Conditions
- Sleep Apnea Syndrome (OSAS), Central Sleep Apnea, Maxillomandibular Advancement Surgery, Orthognathic Surgical Procedures
- Trial name
- CMAI (NCT07596719)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Obstructive Sleep Apnea Syndrome (OSAS)
Acceptance of Mandibular Advancement Devices
Background: Obstructive sleep apnea syndrome (OSAS) is a prevalent condition with significant comorbidities. Mandibular advancement devices (MADs) are an established alternative for patients intolerant to continuous positive…
- Trial name
- NCT06970171
- Testing
- MAD of the Scheu Dental type with lateral guidance wings (MAD-1), MAD of the Panthera X3 type with lateral guidance wings (MAD-2)
- Where
- Germany
- Volunteers
- 28 people
- Sponsor
- University Medicine Greifswald
Sleep Apnea Syndrome (OSAS)
Semaglutide Effects on Sleep Apnea in Patients With Type 2 Diabetes/Obesity and Comorbid Obstructive Sleep Apnea
Semaglutide (a GLP-1RA) is approved for type 2 diabetes mellitus T2DM and obesity, but its effect on obstructive sleep apnea OSA remains unclear.
- Trial name
- NCT07281196
- Testing
- Semaglutide Subcutaneous Injection
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shanghai Fengxian District Central Hospital
Airway Inflammation, Chronic Obstructive Pulmonary Disease (COPD)
Immune Status and Disease Control of Inflammatory Airway Diseases
The goal of this study is to learn how the body's immune system affects disease control in people with different airway inflammatory diseases.We want to understand: 1.Whether specific immune cell patterns in the blood are linked…
- Conditions
- Airway Inflammation, Chronic Obstructive Pulmonary Disease (COPD), Asthma (Diagnosis), Bronchiectasis
- Trial name
- ISDC-IAD (NCT07493629)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Sleep Apnea Syndrome, Obstructive, Sleep Apnea Syndrome (OSAS)
Botulinum Toxin in the Palatopharyngeal Muscle for the Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA) is a sleep-related breathing disorder characterized by recurrent collapse of the upper airway during sleep, in which the palatopharyngeal muscle plays a key role in pathophysiology.
- Conditions
- Sleep Apnea Syndrome, Obstructive, Sleep Apnea Syndrome (OSAS), Sleep Apnea/Hypopnea Syndrome, Sleep Apnea - Obstructive
- Trial name
- ARAP1 (NCT07399782)
- Testing
- BOTULINUM TOXIN IN THE PALATOPHARYGEUS MUSCLE
- Volunteers
- 20 people
- Sponsor
- Hospital Felicio Rocho
Obstructive Sleep Apnea (OSAS), Obstructive Sleep Apnea (SAOS)
Home-based Under Mattress Monitor for OSA
The aim of the study is to evaluate the effectiveness of the under-mattress monitoring device to aid in the titration process of a mandibular advancement device (MAD) for the management of obstructive sleep apnea (OSA).
- Trial name
- NCT07186725
- Testing
- Under-mattress monitor, level 3 Home Sleep Apnea Test, Mandibular Advancement Device (MAD)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Isabel Moreno Hay
Pulmonary Embolism, Sleep Apnea Syndrome (OSAS)
Impact of Sleep Related Breathing Disorders on Outcomes of Acute Pulmonary Embolism
This study aimsto compare short-termclinical outcomesand one-year recurrence rates in patients with acute pulmonary embolism with versus without sleep-disordered breathing, recruited from Alexandria MainUniversityHospital.
- Trial name
- NCT07356908
- Testing
- polysomnography
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Obstructive Sleep Apnea Syndrome (OSAS)
The Effect of Inspiratory Muscle Training on Cognitive Functions, Cerebral Oxygenation, and Neurotrophic Factor Level in Patients With Obstructive Sleep Apnea Syndrome
The aim of this clinical study is to examine the effect of an 8-week training program applied to the respiratory muscles that enable breathing in individuals with obstructive sleep apnea syndrome on cognitive functions…
- Trial name
- NCT07329049
- Testing
- inspiratory muscle training, Usual Care
- Volunteers
- 42 people
- Sponsor
- Istinye University
Chronic Kidney Diseases, OSAS (Obstructive Sleep Apneas Syndrome)
The Outcome of Chronic Kidney Disease Patients With Obstructive Sleep Apnea Syndrome
Obstructive sleep apnea (OSA) is highly prevalent in chronic kidney disease (CKD) patients and strongly linked to obesity, metabolic syndrome, and type 2 diabetes.
- Trial name
- NCT06971874
- Testing
- No intervention
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Obstructive Sleep Apnoea Syndrome (OSAS)
Evaluate the Benefit of an Individualised Treatment Plan (VitalCare) VS SOC in OSA Patients Treated With CPAP/APAP
According to a stratification procedure, the objective of a personalised care plan (VitalCare) is to identify points for improvement since the early stage of the patient's pathway of CPAP/APAP treatment and to adjust patient…
- Trial name
- VitalCare (NCT05246449)
- Testing
- individualised treatment plan (VitalCare) and associated remote medical monitoring
- Where
- Portugal
- Volunteers
- 113 people
- Sponsor
- Air Liquide Santé International
Sleep Apnea Syndrome (OSAS), Sleep Apnea Syndrome
Personalised Treatment for OSA
Obstructive sleep apnea (OSA) is a sleep disorder characterized by repetitive episodes of partial or complete obstruction of the upper airway during sleep.
- Conditions
- Sleep Apnea Syndrome (OSAS), Sleep Apnea Syndrome, Sleep Apnea Syndrome, Obstructive, Sleep Apnea/Hypopnea Syndrome
- Trial name
- NCT06915077
- Where
- Belgium
- Volunteers
- 850 people
- Sponsor
- University Hospital, Antwerp
Delirium, Fatigue
The Impact of Non-motor Symptom on the Outcome of Stroke Subjects
The most common symptoms of stroke were focal weakness, hemiparesis, speech disturbance, diplopia and ataxia. Beside those symptoms, there are still many symptoms occurring after stroke, which may affect the life quality of…
- Conditions
- Delirium, Fatigue, Depression, Insomnia
- Trial name
- NMCHYIS (NCT06854497)
- Testing
- MMSE (Mini-Mental State Examination),NIHSS (NIH Stroke Scale) and mRS (Mordified Rankin Score), Confusion Assessment Methods (CAM), PSQI Pittsburgh Sleep Quality Index, Respiratory polygraphy
- Where
- Taiwan
- Volunteers
- 1,500 people
- Sponsor
- Chiayi Christian Hospital
Sleep Apnea Syndrome, Obstructive, Sleep Apnea Syndrome (OSAS)
The SNORE-trial: Analysis of Alterations in Sleep Stages Following Anesthesia and Their Relation to the Severity of Obstructive Sleep Apnea in the First 3 Nights After Surgery
The goal of this observational study is to learn about the relationship between sleep alterations following anesthesia and their relationship to a potential increase of obstructive sleep apnea (OSA) severity.
- Trial name
- SNORE (NCT06586268)
- Where
- 2 sites in Netherlands
- Volunteers
- 35 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Chronic Obstructive Pulmonary Disease (COPD), Obstructive Sleep Apnea Syndrome (OSAS)
Endothelial Function Study Before Cardiovascular Surgery
The aim of this clinical trial is to evaluate the effect of chronic obstructive pulmonary disease (COPD) and/or obstructive sleep apnea syndrome (OSAS) on the endothelial function, before cardiovascular surgery, compared to non…
- Trial name
- COPD-OSAS (NCT01195064)
- Where
- 3 sites in France
- Volunteers
- 109 people
- Sponsor
- University Hospital, Grenoble
Interface, Mask, Continuous Positive Airway Pressure (CPAP)
CPAP and NIV Interfaces : Side-effects in Home Care Patients
Home ventilation techniques consist mainly of two techniques, Continuous Positive Airway Pressure or CPAP and Non Invasive Ventilation or NIV. Whether for CPAP or NIV, pressures are delivered to the patient via an interface.
- Conditions
- Interface, Mask, Continuous Positive Airway Pressure (CPAP), Non Invasive Ventilation (NIV), Hyperventilation Anxiety
- Trial name
- InterfaceVent (NCT03013283)
- Testing
- self questionnaire
- Where
- 2 sites in France
- Volunteers
- 6,000 people
- Sponsor
- University Hospital, Montpellier