Clinical trials: Obesity, Maternal
Healthy
Maternal Obesity and Offspring Neurodevelopment
Our goals are to characterize the effects of maternal obesity during pregnancy on infant brain development, reveal the neurodevelopmental consequences, and identify possible mechanisms causing these effects.
- Trial name
- Moon (NCT04274140)
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Obesity
The Effect of Obesity on Pregnancy and Fetal Outcome in Glucose Tolerant Mothers
The participants are divided into subjects or controls based on the BMI taken during the first trimester of pregnancy upon recruitment.
- Trial name
- NCT04116268
- Where
- Malaysia
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University Malaysia Sarawak
Adolescent Obesity, Diabetes Mellitus
Black Girls Move Physical Activity and Improving Dietary Intake Among Black Adolescent Daughters
Black Girls Move is a school-linked daughter/mother physical activity and dietary behavior program, with 9th and 10th grade students.
- Trial name
- NCT05433415
- Testing
- Black Girls Move
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Obesity, Water; Lack of
Preventing Early Childhood Obesity, Part 1: Long-term Follow-up
This study extends follow up on of Native American (NA) mothers and their children (now age 3-5 years) enrolled in the 1:1 randomized controlled trial of the Family Spirit Nurture (FSN) intervention designed to prevent early…
- Conditions
- Obesity, Water; Lack of, Childhood Obesity, Feeding Behavior
- Trial name
- PECO1-LTF (NCT05424471)
- Testing
- Family Spirit Nurture (FSN), Control Group - Vehicle Safety
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Overweight, Obese
Post-delivery Maternal-offspring Obesity and Metabolic Risk After a Prepregnancy Weight-loss Intervention
The goal of PrepareD is to examine whether the prepregnancy weight-loss intervention administered during the Prepare trial [NCT02346162] has an influence in the postnatal period.
- Conditions
- Overweight, Obese, Metabolic Disorders, Postpartum
- Trial name
- PrepareD (NCT06067126)
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Kaiser Permanente
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Obesity, Maternal, Gestational Diabetes
Nutrition Optimization and Community Upliftment for Postpartum Recovery
The goal of this clinical trial is to better understand how different strategies, timing, and enhancements to medically tailored food delivery will address structural inequities in the food environment, empower communities to…
- Trial name
- NOURISH-GDM (NCT06445530)
- Testing
- MFeast ENHANCED, MFeast Usual Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Obesity
Delta Healthy Sprouts: Intervention to Promote Maternal Weight Control and Reduce Childhood Obesity in the MS Delta
The Delta Healthy Sprouts Project is a randomized, controlled trial evaluating the enhancement of an existing Mother, Infant, and Early Childhood Home Visiting Program in 150 African American women in their early second trimester…
- Trial name
- NCT01746394
- Testing
- Parents as Teachers Enhanced, Parents as Teachers
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- USDA, Delta Human Nutrition Research Program
Overweight or Obesity
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in childbearing years.
- Trial name
- NCT05674799
- Testing
- NDPP-NextGen
- Where
- United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity, Child Obesity
Feeding the fAmiLy: the Intergenerational approaCh to fIght obesiTY (FACILITY)
The FACILITY STUDY is aimed at evaluating maternal and children social, cultural, economic and lifestyle-related risk factors for the development of childhood overweight, obesity and early adiposity rebound (EAR).
- Conditions
- Obesity, Child Obesity, Maternal Obesity, Overweight
- Trial name
- FACILITY (NCT06179381)
- Volunteers
- 269 people
- Sponsor
- Buzzi Children's Hospital
Obesity/therapy, Prevention and Control
Cognitive-Behavioral Intervention to Increase Tummy Time Practice and Maintain Healthy Weight in Infants
Childhood obesity is a serious health problem worldwide evidenced by its high prevalence, specifically for the age group called the first 1000 days of life.
- Trial name
- NCT06616467
- Testing
- Tummy Time for the prevention of childhood obesity
- Where
- Mexico
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Nuevo Leon
Obesity, Pregnancy
Determination of Maternal and Neonatal Apelinemia in Obese Women During Pregnancy
Background : Apelin and its receptor APJ have been implicated in pathologies including cardiovascular disease, diabetes and obesity. Little is known about the function of the apelinergic system during gestation.
- Conditions
- Obesity, Pregnancy, Gestational Diabetes
- Trial name
- OB-APE (NCT02796456)
- Testing
- blood sample
- Where
- France
- Volunteers
- 135 people
- Sponsor
- University Hospital, Lille
Pregnant Individuals, Obesity & Overweight
Gestational Response, Outcomes, and Weight After GLP-1 Use
The goal of this observational study is to learn if using GLP-1RA medications for weight loss before pregnancy influences gestational weight gain and pregnancy outcomes.
- Conditions
- Pregnant Individuals, Obesity & Overweight, Gestational Weight Gain
- Trial name
- GROW (NCT07743567)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Healthy
Effects of Maternal Obesity on Offspring Brain Development
The goal of this study is to see if there are negative effects of maternal obesity during pregnancy on offspring's brain development.
- Trial name
- NCT03499587
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Diabetes
Food Intake and Appetite in the Children of Mothers With Diabetes
This protocol is for study of the effect of inhibition of parasympathetic outflow on insulin secretion and glucose metabolism. Insulin secretion will be measured during infusions of escalating doses of atropine.
- Trial name
- NCT00339313
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Infant Nutrition
Effect of Formula on Growth of Infants From Overweight or Obese Mothers
The purpose of this study is to determine whether infants, from overweight or obese mothers, fed a formula with proteins and calories different than a standard infant formula have a different growth
- Trial name
- NCT00820833
- Testing
- standard infant formula, Test formula
- Where
- Chile
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Sleep Apnea, Obesity
Sleep Apnea in Pregnancy Screening Study
Obstructive sleep apnea is known to be a significant source of morbidity in the general population. It has been proposed to be associated with the development of preeclampsia and fetal growth restriction.
- Trial name
- SAPSS (NCT01585844)
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Hypertension in Pregnancy, Hypertension
Enhancing Intergenerational Health in Nigeria: Peripartum as Critical Life Stage for Cardiovascular Health
The purpose of the ENHANCE-CVH study is to promote intergenerational cardiovascular health (CVH) of women and children in Abuja and the surrounding Federal Capital Territory of Nigeria.
- Conditions
- Hypertension in Pregnancy, Hypertension, Obesity and Overweight, Maternal Morbidity and Mortality
- Trial name
- ENHANCE-CVH (NCT06773299)
- Testing
- PAT+HEALTH curriculum - Nigeria
- Where
- Nigeria
- Volunteers
- 1,000 people
- Sponsor
- Washington University School of Medicine
Weight Loss, Diet Habit
Koa Family: California's Obesity Prevention Project
The purpose of this study is to learn if a new whole-person lifestyle program improves the health of low-income mothers.
- Conditions
- Weight Loss, Diet Habit, Physical Activity, Overweight and Obesity
- Trial name
- NCT03605888
- Testing
- Koa Family
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- University of California, Davis
Opaque Bottles, Conventional, Clear Bottles
Opaque Bottle Study
The proposed research aimed to conduct an intervention study assessing the effect of feeding mode (clear versus opaque bottle) on the quality and outcome of infant feeding interactions.
- Trial name
- NCT03711370
- Testing
- Clear Bottle, Opaque Bottle
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- California Polytechnic State University-San Luis Obispo