Clinical trials: Obesity, Severe
Morbid Obesity, Laparoscopic Sleeve Gastrectomy
Pan Immune Inflammation Value for Perioperative Complications of Laparoscopic Sleeve Gastrectomy
Morbid obesity emerges as a problem that causes serious complications and increased mortality rates. The most effective treatment for morbid obesity today is surgical treatment.
- Conditions
- Morbid Obesity, Laparoscopic Sleeve Gastrectomy, Post Operative Complicaiton
- Trial name
- NCT06284356
- Testing
- Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Metabolism and Nutrition Disorder, Obesity
Effect of Liraglutide in Obese Subjects With Moderate or Severe Obstructive Sleep Apnoea: SCALE™ - Sleep Apnoea
This trial is conducted in North America. The aim of the trial is to investigate the effect of liraglutide in obese subjects with sleep apnoea.
- Conditions
- Metabolism and Nutrition Disorder, Obesity, Obstructive Sleep Apnoea
- Trial name
- NCT01557166
- Testing
- liraglutide
- Where
- 42 sites in United States, Canada
- Volunteers
- 359 people
- Sponsor
- Novo Nordisk A/S
Morbid Obesity, Surgical Management by Laparoscopic Sleeve Gastrectomy
Kinematics of Obese Patients Perambulation
The aim of this study is to evaluate the consequences of sleeve gastrectomy on functional parameters of patients perambulation.
- Trial name
- MARCHOBESE (NCT01774682)
- Testing
- 6-minute walk test
- Where
- France
- Volunteers
- 99 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Morbid Obesity, Vitamin D Deficiency
Effect of a Monthly High Dose of Vitamin D3 on Bariatric Surgery Patients
Bariatric surgery patients tend to have malabsorption of many micronutrients such as B12, Iron and vitamin D postoperative. So in this study, a monthly high dose of vitamin D3 is giving to patients with their routine supplements…
- Trial name
- NCT02477956
- Testing
- vitamin D3 (Replesta), vitamin D
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Texas Tech University
Morbid Obesity, Bariatric Surgery Patient
Appetite Suppression / Hormone Study Control Group
The purpose of this research study is to determine how changes in levels of obesity-related hormones in the gastrointestinal tract following Laparoscopic Adjustable Gastric Banding (LAGB) surgery may lead to a decrease in…
- Trial name
- NCT02029677
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Oregon Weight Loss Surgery, LLC
Mental Illness Persistent, Chronic Disease
Reverse Colocated Integrated Care Intervention Among Persons With Severe Persistent Mental Illness at US-Mexico Border
This study evaluated whether patients with severe and persistent mental illness (SPMI) who received coordinated co-located behavioral health and primary care services were more likely to improve health outcomes after 12 months…
- Conditions
- Mental Illness Persistent, Chronic Disease, Hypertension, Diabetes
- Trial name
- NCT03881657
- Testing
- Reverse Colocated Integrated Care, Usual Care
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Health Resources in Action, Inc.
Obesity
Diastolic Dysfunction During Conservative Lifestyle Treatment
The Purpose of this study is to 1) investigate prevalence of diastolic dysfunction in patients with morbid obesity attending a conservative lifestyle change program, 2) investigate effects on cardiac function, cardiorespiratory…
- Trial name
- NCT02826122
- Testing
- Pai APP, FitBit APP
- Where
- Norway
- Volunteers
- 57 people
- Sponsor
- Norwegian University of Science and Technology
Bariatric Surgeries
Food and Gastrointestinal Habits After Bariatric Surgery
The worldwide epidemic of overweight and obesity affects about 1.7 billion people around the world. Since 1991, many international medical societies have established as recommendation for bariatric surgery the unsuccessful…
- Trial name
- NCT01224054
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- University of Campinas, Brazil
Morbid Obesity
Local GIT Hormones After Bariatric Maneuvers
Background: Many of the beneficial metabolic effects of bariatric surgery have been attributed to altered peptide hormone profiles, especially involving pancreatic and gut peptides.
- Trial name
- NCT04414072
- Testing
- sleeve gastrectomy with loop bipartition
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Obesity, Morbid Obesity
Obesity, Lifestyle and Work Intervention
The main aim of this study was to examine whether introducing a work intervention into a traditional lifestyle rehabilitation program for persons with BMI above 30, would affect the participants' ability to work and their…
- Conditions
- Obesity, Morbid Obesity, Sick-leave, Work Related Illnesses
- Trial name
- NCT03886870
- Testing
- Lifestyle and work intervention, Lifestyle intervention
- Volunteers
- 140 people
- Sponsor
- Molde University College
Morbid Obesity
Clinical Staging Tools for the Impacts of Obesity on Individuals
This study will assess various published staging tools to assess the health impacts of obesity on individuals. The aim is to identify benefits and drawbacks, and thus help Obesity Centres and GPs better assess obese individuals…
- Trial name
- COST (NCT01112228)
- Testing
- Bariatric surgery
- Where
- United Kingdom
- Volunteers
- 600 people
- Sponsor
- Imperial College London
Morbid Obesity
Bioavailability of Paracetamol, Amoxicillin and Talinolol Before, Immediately and One Year After Gastric Bypass Operation
The purpose of this study is to evaluate pharmacokinetics of paracetamol, amoxicillin and talinolol in morbid adipose subjects before as well as shortly after and about one year after proximal Roux-en-Y Gastric Bypass (RYGB) and…
- Trial name
- NCT02514941
- Testing
- paracetamol, amoxicillin, talinolol
- Where
- 2 sites in Germany
- Volunteers
- 12 people
- Sponsor
- University Medicine Greifswald
Severe Obesity
Muscle Strength in Severe Obese Patients in the Postoperative of Bariatric Surgery
Excessive fat mass (FM) contributes to changes in the strength and endurance of skeletal muscles. Mid-thigh muscle mass is approximately 2.5 times that of fat mass, but individuals who are obese have increased intra- (fat within…
- Trial name
- NCT04129801
- Testing
- Isokinetic Dynamometer, Bioimpedance
- Where
- Brazil
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Hypogonadism, Hypogonadotropic, Obesity
Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism
The investigators have preliminary data suggesting that obese patients with hypogonadotropic hypogonadism (HHG) have minimal benefit from testosterone therapy likely because of its conversion to estradiol by the abundant…
- Trial name
- NCT03490513
- Testing
- anastrozole (1 mg/day)
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Baylor College of Medicine
Polycystic Ovary Syndrome, Severe Obesity
Effect of Metabolic Surgery on Live Birth Rate of Offspring in Obesity Polycystic Ovarian Syndrome Patients
This is a experimental study, which subjects are obese PCOS patients requiring LSG surgery. Aim to investigate the effects of LSG surgery in PCOS patients whether increases the live birth rate of the offspring.
- Conditions
- Polycystic Ovary Syndrome, Severe Obesity, Laparoscopic Sleeve Gastrectomy
- Trial name
- NCT04151459
- Testing
- Metformin
- Where
- China
- Volunteers
- 18 people
- Sponsor
- RenJi Hospital
Clinically Severe Obesity, Gastroesophageal Reflux Disease
Gastric Bypass After Previous Anti-reflux Surgery
The goal of this study is to describe the clinical presentation, indications, and operative treatment as well as assess the morbidity, mortality, and overall performance of revisional Roux-en-Y gastric bypass (RYGB) after either…
- Trial name
- RYGBafterARS (NCT01041105)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of California, San Francisco
Morbid Obesity
Endoscopic Gastric Tubulization
Endoscopic gastric tubulization is currently proposed in the Digestive Surgery Department of the Nouvel Hôpital Civil, Strasbourg, France, to adult patients with morbid obesity.
- Trial name
- Endosleeve (NCT03554902)
- Testing
- Endoscopic gastric tubulization
- Where
- France
- Volunteers
- 300 people
- Sponsor
- IHU Strasbourg
Severe Obesity, Sleeve Gastrectomy
Longitudinal Retrospective Analysis of Prospectively Collected Data for Outcomes After Primary Sleeve Gastrectomy (N=20 000) in the Swedish National Quality Registry SOReg (Scandinavian Obesity Surgery Registry)
The main questions to answer are: Weight outcomes in weight strata over time? What was the proportion of patients reaching sufficient weight outcome in different weight strata? To what extent are co-morbid conditions improved or…
- Trial name
- SCAN (NCT07280845)
- Where
- Sweden
- Volunteers
- 19,977 people
- Sponsor
- Linkoeping University
Morbid Obesity
Lifestyleintervention for the Treatment of Severe Obesity
The overall purpose of this project is to study the acute, short- (≤ 1 year) and long- (> 1 year) term effects on body composition and psychological health after a 10 to 14-weeks comprehensive lifestyle modification program for…
- Trial name
- NCT01675713
- Testing
- Intensive lifestyle intervention
- Where
- Norway
- Volunteers
- 149 people
- Sponsor
- Norwegian School of Sport Sciences
Sleeve Gastrectomy With Jejunoileal Anastomosis
Evaluation of Patients Who Underwent Sleeve Gastrectomy With Jejunoileal Anastomosis for the Treatment of Morbid Obesity
Laparoscopic sleeve gastrectomy operations performed for morbid obesity are among the most common methods in the world. Gastric or intestinal bypass surgery with or without sleeve gastrectomy is thought to be more effective in…
- Trial name
- NCT03939442
- Testing
- Sleeve gastrectomy with jejunoileal anastomosis
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Inonu University