Clinical trials: Obesity; Overweight
Obesity and Overweight, Diabetes Mellitus
FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)
The goal of this clinical trial is to learn the best combination of family components that yields optimal weight loss among Black adults.
- Conditions
- Obesity and Overweight, Diabetes Mellitus, Weight Loss, Behavior Change
- Trial name
- FAM WEL B-ing (NCT06724406)
- Testing
- Family Skills Training Session Quantity: 5, Family Skills Training Session Mode: In-person, Family Skills Training Content: Communication
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of North Carolina, Chapel Hill
Lipedema, Obesity
Microbiota and Lipedema Evaluation in Obese Patient Treated With Very Low Energy Ketogenic Vegan Therapy
Lipedema is a progressive, hereditary, multifactorial disease that occurs primarily in women, characterized by an abnormal and painful accumulation of subcutaneous fatty tissue.
- Conditions
- Lipedema, Obesity, Dysbiosis
- Trial name
- MLVLEKVT (NCT07041684)
- Testing
- Very Low Energy Ketogenic Therapy with vegan meal replacements
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University of Roma La Sapienza
Obesity, Overweight
Evaluating a Remotely Delivered Plant-Based Behavioral Weight Loss Treatment
Many individuals do not achieve clinically significant weight loss following traditional lifestyle modification interventions, potentially because weight loss is dependent upon calorie tracking compliance (to achieve calorie…
- Trial name
- NCT04892030
- Testing
- Whole Food Plant-Based Behavioral Weight Loss Treatment
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Drexel University
Obesity
Time Restricted Eating for Weight Loss Maintenance
The aim of this pilot feasibility and acceptability, randomized clinical trial will be to examine the effects of two-time restricted eating (TRE) interventions on weight loss maintenance (WLM).
- Trial name
- TWIST (NCT05742165)
- Testing
- Time Restricted Eating (TRE)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- NYU Langone Health
Chronic Hypercapnic Respiratory Failure, Obesity Hypoventilation Syndrome
Randomized Controlled Trial Between Auto-titration and Manual Titration of Non-invasive Ventilation in Obesity Hypoventilation Syndrome
Primary Objectives: To evaluate the effectiveness in the obesity hypoventilation syndrome (OHS) treatment with non-invasive ventilation (NIV) set manually by polysomnography compared to the same treatment with a respirator with…
- Trial name
- TITRATION (NCT04327336)
- Testing
- Manual Non invasive ventilation titration, Automatic Non invasive ventilation titration
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Sociedad Española de Neumología y Cirugía Torácica
Diabetes, Obesity
A Trial of the Jejunal Diversion Procedure
This is a single site trial to assess metabolic effects in subjects after a Jejunal Diversion procedure was performed.
- Trial name
- NCT02283632
- Testing
- Jejunal Diversion
- Where
- Czechia
- Volunteers
- 15 people
- Sponsor
- Ethicon Endo-Surgery
Overweight, Obesity
A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity
The purpose of this clinical study is to find out if UBT251 is safe and effective for treating people who are living with overweight or obesity.
- Trial name
- NCT07395687
- Testing
- UBT251
- Where
- 3 sites in United States, Canada
- Volunteers
- 333 people
- Sponsor
- Novo Nordisk A/S
Obesity, Childhood
A Trial to Increase Child Vegetable Intake Through Behavioral Strategies
A community nutrition trial among a diverse low-income population that tested the effect of parent-child cooking nutrition intervention on vegetable intake among 9-12 children.
- Trial name
- NCT03641521
- Testing
- Parent-led behavioral strategies
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Prader-Willi Syndrome, Obesity
Improving Care of Prader-Willi Syndrome : Evaluation of a New Care Program Combining Adapted Physical Activity, Nutrition and Therapeutic Education
Prader-Willi syndrome (PWS) is a rare and complex genetic disease characterized by hypothalamic-pituitary axis dysfunction combining eating disorders associated with hyperphagia and satiety deficiency, mild intellectual deficit…
- Trial name
- APHYNET (NCT05249998)
- Testing
- Program combing APA, Nutrition, and Therapeutic Education
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Weight Loss
Active Nutrition Program on Weight Loss
The study will evaluate the impact of the Active Nutrition 60-day program from USANA on weight loss and related measures, such as body composition, physical appearance/body shape, perceived wellness, and biochemical markers of…
- Trial name
- NCT06249698
- Testing
- meal replacements and supplements
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Obesity
Studying the Effects of Sibutramine on Eating Behavior
Obesity is a major public health concern, and the search for useful pharmacologic interventions is ongoing. This study aims to develop a comprehensive series of assessments to directly assess eating behavior, cognitive…
- Trial name
- NCT01170364
- Testing
- Sibutramine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- New York State Psychiatric Institute
Fetal Weight, Obesity, Morbid
Comparison of Three Methods for Fetal Weight Estimation
The aim of this study was to compare maternal, clinical and ultrasound estimations of fetal weight in women with severe (BMI>35) and morbid (BMI>40) obesity and to determine the effect of maternal body mass index (BMI) on these…
- Conditions
- Fetal Weight, Obesity, Morbid, Pregnancy Related
- Trial name
- NCT05478798
- Testing
- ultrasonographic fetal weight estimation, clinical fetal weight estimation, maternal subjective fetal weight estimation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Childhood Obesity, Treatment Adherence
The Evira Study: Additional Support During Obesity Treatment
The goal of this clinical trial is to evaluate the effect of adding a digi-physical treatment tool as a complement to the local treatment with obesity medication in adolescents with obesity.
- Trial name
- NCT06836284
- Testing
- Digi-physical treatment tool, Evira, Obesity medication with liraglutide or semaglutide
- Where
- 3 sites in Sweden
- Volunteers
- 40 people
- Sponsor
- Karolinska Institutet
Obesity
Dietary, Physiological, Genetic, and Behavioral Predictors of Health in a Young, Ethnically-Mixed Population
Dietary intervention and other strategies to prevent unhealthy weight gain and the development of obesity should be based on knowledge of dietary, physiological, genetic and behavioral determinants and their contributing…
- Trial name
- InSight (NCT00945633)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity
Olfactory Odour Stimulation for Metabolism Control
In this preliminary short-term study it is investigated, whether a short olfactory stimulation with D-Limonene leads to an acute improvement of glucose metabolism in patients with obesity.
- Trial name
- OLFAMET (NCT04223284)
- Testing
- D-Limonene, SLVO
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- University Hospital, Basel, Switzerland
Obesity, Overweight
The Influence of Physical Activity on the Gut Microbiome of Pre-Diabetic Adults
The present study is a 100-participant randomized controlled 2-arm parallel trial that employs a metagenomic approach to examine how 8 weeks of supervised moderate-intensity treadmill walking exercise (MWE) for 30-45 min 3…
- Conditions
- Obesity, Overweight, Overweight and Obesity, PreDiabetes
- Trial name
- NCT04931836
- Testing
- Physical Activity Intervention
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- University of Minnesota
Non-Alcoholic Fatty Liver Disease, Obesity
Multicenter, Randomized, Controlled and Double-blind Study of Efficacy and Safety of Endoscopic Gastric Tubulization in Patients With Non-alcoholic Steatohepatitis (NASH-APOLLO).
Nonalcoholic steatohepatitis is a growing public health problem affecting over 5% of the population. These patients are at increased risk of cardiovascular and liver-related death and have higher rates of malignancy.
- Trial name
- NASH-APOLLO (NCT03426111)
- Testing
- Endoscopic Gastric Tubulization with OverStitch® system (Apollo Endosurgery, Austin, TX, USA), Lifestyle modification
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Puerta de Hierro University Hospital
Obesity
Research Study Looking at How Well Semaglutide Works in People Living With Obesity and Prediabetes
This study looks at how well a new medicine, called semaglutide, works at helping people with obesity and prediabetes. This study will look at how much weight participants lose, and if participants can go from having blood sugar…
- Trial name
- STEP 10 (NCT05040971)
- Testing
- Semaglutide 2.4 mg
- Where
- 43 sites in Canada, Denmark and 3 more
- Volunteers
- 207 people
- Sponsor
- Novo Nordisk A/S
Overweight and Obesity
Effect of Açaí Juçara Consumption on Endothelial Function and Arterial Stiffness
This study evaluates the consumption of Açaí Juçara pulp in endothelial function and arterial stiffness in overwheight and obese individuals.
- Trial name
- NCT04434534
- Testing
- Hipocaloric Diet with Açaí Juçara, Hipocaloric Diet
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Bariatric Surgery, Anesthesia, General
Predictors of Anesthesia Complications in Patients Undergoing Bariatric Surgery
This study aims to identify factors that can predict complications related to anesthesia in patients undergoing weight-loss surgery.
- Conditions
- Bariatric Surgery, Anesthesia, General, Postoperative Complications, Obesity
- Trial name
- NCT06981793
- Where
- France
- Volunteers
- 125 people
- Sponsor
- Centre Hospitalier de Gonesse