Clinical trials: Obesity and Cardiovascular Risk
Obese Adults
Evaluation of the Effects of Systemic Vibration Therapy on Thermogenesis, Cardiovascular Parameters, Endocrine-inflammatory Markers, and Physical-functional Performance in Adults With Obesity.
The goal of this clinical trial was to evaluate the effects of Systemic Vibration Therapy (SVT) on thermogenesis, cardiovascular health, endocrine-inflammatory markers, and physical performance in adults (men and women, aged…
- Trial name
- SVT (NCT07729215)
- Testing
- Systemic vibratory therapy, Systemic vibration therapy
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Laboratorio de Vibraçoes Mecanicas e Praticas Integrativas
Obesity, Diabetes
Effect of a Treatment of Lifestyle Changes on the Prevalence of Metabolic Syndrome and Body Weight in Mexican Women
The metabolic syndrome is a group of cardiometabolic risk factors that reflect a sedentary lifestyle and the excessive intake of food among the risk factors that comprise it are located the obesity, hyperglycemia, dyslipidemia…
- Conditions
- Obesity, Diabetes, High Blood Pressure, Dyslipidemia
- Trial name
- MPATPCDNC (NCT02247635)
- Testing
- Healthy lifestyle and adherence
- Where
- Mexico
- Volunteers
- 180 people
- Sponsor
- Mexican National Institute of Public Health
Inflammation, Obesity
Systemic and White Adipose Tissue Inflammatory Profile in Lean Versus Obese Individuals
This study will compare the systemic and white adipose tissue inflammatory profile of individuals who are classified as lean and obese.
- Conditions
- Inflammation, Obesity, Inflammatory Response, Cardiovascular Risk Factor
- Trial name
- NCT04078776
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Obesity
Longitudinal Follow-up of Brown Adipose Tissue Function and Structure
In Turku PET Centre, there have been 3 positron emission tomography studies on brown adipose tissue (BAT) activity in healthy adults. BATPET was performed between 2008 and 2009.
- Trial name
- BATFollowUp (NCT01985503)
- Where
- Finland
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Sedentary Lifestyle, Obesity
Reduce Sedentary Behavior at Work
Prior research suggests that sedentary behavior is detrimental to health, independent of exercise activity. Sedentary behavior is defined as behaviors that involve low levels of energy expenditure ≤1.5 metabolic equivalents…
- Conditions
- Sedentary Lifestyle, Obesity, Cardiovascular Risk Factor
- Trial name
- NCT03816150
- Volunteers
- 16 people
- Sponsor
- Medical College of Wisconsin
Cardiovascular Disease, Diabetes
Taste Perception and Chronic Disease Risk
The purpose of the Taste Perception Study is to assess variations in the ability to taste and perceive sensations from various stimuli in younger (18-49 years) and older (50-85 years) volunteers.
- Conditions
- Cardiovascular Disease, Diabetes, Obesity, Metabolic Syndrome
- Trial name
- NCT01023906
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tufts University
Cardiovascular Diseases, Heart Diseases
Partnership Programs to Reduce Ethnic Differences in the Risk of Cardiovascular Disease
The purpose of this study is to improve cardiovascular disease (CVD) outcomes in racial and ethnic minorities. Specifically, the study seeks to systematically characterize potential ethnic differences in obesity-related CVD by…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Obesity, Metabolic Syndrome X
- Trial name
- META-HEALTH (NCT00101517)
- Where
- 2 sites in United States
- Volunteers
- 4,024 people, healthy volunteers welcome
- Sponsor
- Emory University
Cardiovascular Risk Factor, Prediabetes
Active You: Feasibility of a Unique Physical Activity Program to Prevent Diabetes and Heart Disease
Individuals who are overweight/obese are more vulnerable to type 2 diabetes (T2D). Current evidence suggests that PA, even without dietary prescription, can be efficacious in preventing T2D.
- Conditions
- Cardiovascular Risk Factor, Prediabetes, Overweight and Obesity, Sedentary Behavior
- Trial name
- NCT04621045
- Testing
- The Physical Activity for The Heart (PATH) intervention, Be Active Your Way Booklet
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity, CVD
Effects of a 5:2 Diet on Weight Loss and Cardiovascular Risk Factors in Obesity
A randomized clinical trial comparing the effect on weight reduction and cardiometabolic risk factors of intermittent energy restriction and a isocaloric continuous energy restriction in obese subjects.
- Conditions
- Obesity, CVD, Dietary Modification
- Trial name
- NCT02480504
- Testing
- dietary intervention intermittent energy restriction, continuous energy restriction
- Where
- Norway
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Cardiovascular Diseases, Diabetes
Białystok PLUS - Polish Longitudinal University Study
The main goal of the study is to provide a unique multidimensional picture of the health of the population with simultaneous optimal standards of sampling, processing and storing of data and biomaterial that will allow…
- Conditions
- Cardiovascular Diseases, Diabetes, Neuro-Degenerative Disease, Obesity
- Trial name
- Bialystok+ (NCT03197363)
- Testing
- Discovering novel risk factors.
- Where
- Poland
- Volunteers
- 8,320 people
- Sponsor
- Medical University of Bialystok
Diabetes Mellitus
Preventing Renal Functional Abnormalities With Calorie Restriction in Subjects With Abdominal Obesity and Type 2 Diabetes at Increased Renal and Cardiovascular Risk
The study investigates whether a caloric restricted dietary regime can prevent onset and/or progression of chronic kidney disease in type 2 diabetic patients with abdominal obesity, through the amelioration of concomitant…
- Trial name
- CRESO (NCT01213212)
- Testing
- Caloric restriction, No intervention
- Where
- Italy
- Volunteers
- 73 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Cardiovascular Diseases, Hypertension
Genetic Epidemiology--Development of Cardiovascular Risk
To determine how genetic and environmental factors influence the co-occurrence of obesity and hypertension during development and to identify cardiovascular risk factors in adolescence that will predict cardiovascular disease in…
- Conditions
- Cardiovascular Diseases, Hypertension, Obesity, Heart Diseases
- Trial name
- NCT00005512
- Sponsor
- Virginia Commonwealth University
Gonorrhea, Chlamydia Infections
Risk Assessment of Long-Haul Truck Drivers
International studies have repeatedly documented a substantial prevalence of sexual risk behaviors and high rates of human immunodeficiency virus (HIV) and other sexually transmitted infections (STI) ranging from 5%-56% amongst…
- Conditions
- Gonorrhea, Chlamydia Infections, Hepatitis B, Hepatitis C
- Trial name
- NCT00381992
- Where
- United States
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Overweight and Obesity, Cardiovascular Diseases
Beneficial Effects of Dietary and Lifestyle Change in Overweight and Obese Subjects
Obesity and overweight are noncommunicable diseases with increasing incidence in children, adolescents and adults. In 2016, more than 1.9 billion adults aged 18 and over were overweight and over 650 million were obese (WHO).
- Conditions
- Overweight and Obesity, Cardiovascular Diseases, Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease
- Trial name
- Healthy-MET (NCT05447351)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Bari
Overweight, Obesity
The Impact of Stationary Combined Exercise on Adiponectin and Hs-CRP Levels in Overweight Women
This study looked at whether a specific exercise program can improve inflammatory markers in overweight young women. We tested an eight-week, circuit-style exercise program that combines aerobic and resistance activities (e.g.…
- Conditions
- Overweight, Obesity, Inflammation, Low-Grade, Cardiovascular Diseases, Risk Factors
- Trial name
- SCEX-ADCRP (NCT07230873)
- Testing
- Combined Exercise Group, No Structured Exercise
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Xianjie Zheng
Obesity
Effects of a Ketogenic Diet on Body Weight and Cardiovascular Risk Factors
This pilot study is a randomized, controlled clinical trial to compare anthropometric and metabolic changes associated with six months of weight management by means of a very low carbohydrate diet or a calorically-restricted low…
- Trial name
- NCT00498394
- Testing
- Clinical diet trial
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Abdominal Obesity, Metabolic Syndrome
WAVE Study- Walking and Aging in VErona Study
Monocentric unblinded two parallel-group randomized controlled trial to evaluate the effect of diet with or without Nordic Walking on weight loss, physical performance and cardiovascular risk factors in overweight and obese…
- Conditions
- Abdominal Obesity, Metabolic Syndrome, Disability Physical, Sarcopenic Obesity
- Trial name
- WAVE (NCT03212391)
- Testing
- Diet, Walking, Nordic Walking
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Obesity, Overweight
A Trial of One to One Weight Management in Primary Care
The purpose of this study is to conduct a randomised controlled trial to assess the sustained effects on weight, selected risk factors and sense of well-being of offering individualized weight management advice in the primary…
- Trial name
- NCT00891943
- Testing
- Structured lifestyle support
- Where
- 2 sites in United Kingdom
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Healthy Participants, Obesity
A Study Investigating the Safety, Absorption, Elimination, and the Effect on the Immune System of ACI-19764 in Healthy Participants and in Participants With Cardiovascular Risk Factors
The main purposes of this study are: to investigate the safety and tolerability of ACI-19764 when it is administered to healthy participants and participants with cardiovascular risk factors to determine how quickly and to what…
- Conditions
- Healthy Participants, Obesity, Type 2 Diabetes Mellitus (T2DM)
- Trial name
- NCT07463196
- Testing
- ACI-19764 at dose A1, ACI-19764 at dose A2, ACI-19764 at dose A3
- Where
- Netherlands
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- AC Immune SA
Hypertension, Type 2 Diabetes
Lifestyle Intervention in Primary Health Care - the Björknäs Study
The purpose of this study is to determine whether a short group intervention programe aiming at lifestyle changes at a local health centre can improve risk factors for cardiovascular disease
- Conditions
- Hypertension, Type 2 Diabetes, Obesity, Dyslipidemia
- Trial name
- NCT00486941
- Testing
- Exercise and diet - based on DPS and DPP
- Where
- Sweden
- Volunteers
- 151 people
- Sponsor
- Umeå University