Clinical trials: Obscure Gastrointestinal Bleeding
Obscure Gastrointestinal Bleeding
Preparation Regimens to Improve Capsule Endoscopy Visualization and Diagnostic Yield
Small bowel capsule endoscopy (SBCE) has become an important tool in clinical practice since its introduction in 2000. This non-invasive method allows the visualization of small bowel mucosa, being essential in the management of…
- Trial name
- PrepRICE (NCT05140057)
- Testing
- Moviprep
- Where
- Portugal
- Volunteers
- 210 people
- Sponsor
- Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E.
Lower Gastrointestinal Bleeding
Oakland-Jairath Score Validation
Lower gastrointestinal bleeding (LGIB) is a common presentation in the Emergency Room. It can deteriorate into severe adverse event. However some are discharged before these events occur.
- Trial name
- NCT03935360
- Testing
- Oakland-Jairath Risk Score
- Where
- 6 sites in Canada
- Volunteers
- 344 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obscure Gastrointestinal Bleeding
Cap Assisted Balloon Enteroscopy Versus Conventional Balloon Enteroscopy In The Evaluation Of Obscure Gastrointestinal Bleeding: A Randomized Controlled Trial
Gastrointestinal bleeding originating from the small bowel is difficult to diagnose and treat because the small bowel is difficult to see and reach.
- Trial name
- NCT02315404
- Testing
- CAP
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Washington University School of Medicine
Obscure Gastrointestinal Bleeding
Capsule Endoscopy in Obscure GI Bleeding
The purpose of this study is to conduct a cost-effectiveness analysis of wireless capsule endoscopy in the investigation of patients with overt obscure gastrointestinal bleeding.
- Trial name
- NCT00203619
- Testing
- Wireless capsule endoscopy, standard care
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Hemorrhage, Anemia
Capsule Endoscopy Versus Conservative Therapy for Obscure Gastrointestinal Bleeding
This study is a single center prospective randomized control trial comparing the utility of performing capsule endoscopy compared to conservative management with oral iron therapy as the initial course of action in patients with…
- Trial name
- NCT01837030
- Testing
- Ferrous sulfate, Capsule Endoscopy
- Where
- United States
- Sponsor
- Medical University of South Carolina
Gastrointestinal Bleeding
The Effectiveness of Video-capsule Endoscopy in Gastrointestinal Bleeding of Obscure Origin
The study objective is to compare the cost-effectiveness of VCE to push enteroscopy in patients with gastrointestinal bleeding of obscure origin with a negative initial work-up.
- Trial name
- NCT01424254
- Testing
- Capsule GIVEN IMAGING, Push-Enteroscopy
- Where
- Canada
- Volunteers
- 79 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Obscure Gastrointestinal Bleeding
Single Balloon Enterosocpy Obscure Gastrointestinal Bleeding Bleed
The goal of the present study is to investigate the clinical outcomes of patients with gastrointestinal bleeding originating from the small intestine following diagnostic investigation with single balloon enteroscopy.
- Trial name
- NCT01625585
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- Washington University School of Medicine
Obscure Gastrointestinal Bleeding, Angiodysplasia
Long-term Effects of Thalidomide for Recurrent Gastrointestinal Bleeding Due to Vascular Malformation
Background: Repeated episodes of bleeding from gastrointestinal vascular malformations refractory to endoscopic or surgical therapy often pose a major therapeutic challenge.
- Conditions
- Obscure Gastrointestinal Bleeding, Angiodysplasia, Gastric Antral Vascular Ectasia, Thalidomide
- Trial name
- NCT00964496
- Testing
- Thalidomide, Iron
- Volunteers
- 55 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Gastrointestinal Bleeding
Risk Factors for Rebleeding in Patients With Obscure Gastrointestinal Bleeding
The investigators investigated the rebleeding rate the risk factors for rebleeding after long-term follow-up (≥12 months) in patients who underwent capsule endoscopy for obscure gastrointestinal bleeding.
- Trial name
- NCT01821326
- Volunteers
- 339 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Gastrointestinal Bleeding
Efficacy of Wireless Capsule Endoscopy and CT Enterography in Obscure Gastrointestinal Bleeding
The purpose of this study is to compare the efficacy between video capsule endoscopy and CT enterography in diagnosis of obscure gastrointestinal bleeding.
- Trial name
- NCT02219568
- Testing
- CT enterography, video capsule endoscopy
- Where
- Thailand
- Volunteers
- 52 people
- Sponsor
- Mahidol University
Obscure Gastrointestinal Bleeding, Anemia, Iron Deficiency
Depth of Maximal Ileal Insertion During Retrograde Enteroscopy With TTS Balloon
Diagnostic modalities for the evaluation of small bowel pathology include video capsule endoscopy (VCE), antegrade and retrograde device-assisted enteroscopy, CT and MR enterography (1).
- Trial name
- NaviAid2 (NCT04646083)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Capsule Endoscopes
Evaluation of Obscure Gastrointestinal Bleeding Patients With Conventional Capsule Endoscopy and Panoramic Side View Capsule Endoscopy
With the development of endoscopy, patients with suspected gastrointestinal tract disease can be evaluated with further management.
- Trial name
- NCT04568343
- Testing
- Capsule endoscopy
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Iron Deficiency Anemia
Capsule Endoscopy vs Standard of Care for Obscure Intestinal Bleeding
The role of capsule endoscopy (CE) in patients with obscure / occult gastrointestinal (GI) bleeding remains unclear. This pragmatic randomized controlled trial is designed to determine the diagnostic yield and clinical outcomes…
- Trial name
- NCT00694954
- Testing
- Diagnostic Test - Given Imaging Pillcam, Diagnostics
- Where
- Canada
- Volunteers
- 160 people
- Sponsor
- University of Calgary
Obscure Gastrointestinal Bleeding, Iron-Deficiency Anemia
Endoscopic Evaluation for Iron Deficiency Anemia in Patients on Antithrombotic Therapy
This is a single-center, randomized pilot study evaluating the feasibility and safety of two management strategies for patients on antithrombotic therapy who present with obscure gastrointestinal bleeding (OGIB).
- Conditions
- Obscure Gastrointestinal Bleeding, Iron-Deficiency Anemia, Antithrombotic Therapy
- Trial name
- BEACON-IDA (NCT07089030)
- Testing
- Standard endoscopic evaluation, Conservative Medical Management
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec
Occult Gastrointestinal Bleeding
Capsule Endoscopy vs. Push Enteroscopy in Occult Gastrointestinal Bleeding OGIB
Capsule endoscopy (CE) is a safe and effective tool for the assessment of obscure gastrointestinal bleeding (OGIB). However, its real efficacy and its position in the diagnostic algorithm of OGIB vs.
- Trial name
- NCT00224627
- Testing
- Capsule GIVEN IMAGING LTD
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obscure Gastrointestinal Bleeding (Occult or Overt)
Trial of Wireless Capsule Endoscopy in the Evaluation of Obscure Gastrointestinal Bleeding
This study compares wireless capsule endoscopy (patients swallow a pill-size camera that sends pictures of the intestine to a recorder worn on their belt) to an x-ray study (called dedicated small bowel contrast radiography) in…
- Trial name
- NCT01006824
- Testing
- Capsule endoscopy, Dedicated small bowel contrast radiography
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Southern California
Iron Deficiency Anemia, Obscure Gastrointestinal Bleeding
Role of AI in CE for the Identification of SB Lesions in Patients With Small Intestinal Bleeding.
Capsule Endoscopy (CE) is a safe, patient friendly and easy procedure performed for the evaluation of gastrointestinal tract unable to be explored via conventional endoscopy.
- Trial name
- ArtIC (NCT04821349)
- Testing
- Capsule endoscopy
- Where
- Italy
- Volunteers
- 137 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Recurrent Gastrointestinal Bleeding
Computed Tomography Enterography (CTE) Versus Capsule Endoscopy for Overt, Obscure Gastrointestinal (GI) Bleeding
Up to 5% of patients with recurrent gastrointestinal (GI) bleeding remain undiagnosed by upper endoscopy and colonoscopy, the presumed source of bleeding in these patients being the small intestine.
- Trial name
- NCT01114295
- Testing
- Capsule Endoscopy, CT Enterography
- Sponsor
- Brigham and Women's Hospital
Obscure Gastrointestinal Bleeding, Gastrointestinal Diseases
Assessing Depth of Small Bowel Insertion at Push Enteroscopy by Using Capsule Endoscopy
Bleeding from the gastrointestinal tract can originate from the small bowel. Typically, upper and lower endoscopies are unable to identify the site of bleeding and patients need to undergo special endoscopies with longer cameras…
- Conditions
- Obscure Gastrointestinal Bleeding, Gastrointestinal Diseases, Gastrointestinal Bleed, Angiodysplasia Intestine
- Trial name
- NCT05731388
- Testing
- Push enteroscopy
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- Unity Health Toronto
Gastrointestinal Bleeding
Occult Obscure Gastrointestinal Bleeding
To test the activity of a polyglucosamine (PG) together with a Standard Management protocol (SM) on the occult and obscure gastrointestinal bleeding (OGIB) and the clinical symptoms in patients suffering from colonic…
- Trial name
- OGIB (NCT03464539)
- Testing
- PG low molecular weight chitosan
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Blymum Srl