Clinical trials: Observational
Uterine Fibroid, Uterine Sarcoma
A Prospective Validation Study of Radiomics in the Differential Diagnosis of Uterine Leiomyoma and Uterine Sarcoma
In our previous study, based on the multi-center clinical big data collected from January 2012 to January 2025, we have completed the construction of a multimodal early warning model for the malignant transformation of uterine…
- Conditions
- Uterine Fibroid, Uterine Sarcoma, AI (Artificial Intelligence), Radiomic
- Trial name
- NCT07269535
- Testing
- No intervention (observational study)
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Acute STEMI, PPCI
On vs Off-hour PPCI in STEMI Patients
ST-elevation myocardial infarction (STEMI) remains a leading cause of morbidity and mortality globally, and timely reperfusion with primary percutaneous coronary intervention (PPCI) is the gold-standard treatment1.
- Conditions
- Acute STEMI, PPCI, Observational Study, Coronary Artery Disease (CAD)
- Trial name
- On vs Off PPCI (NCT07860086)
- Where
- Egypt
- Volunteers
- 450 people
- Sponsor
- Assiut University
Social Isolation or Loneliness, Anxiety
Health Surveillance at Constructor University Bremen (CUB)
The aim of Health Surveillance is to analyze and describe the state of health of students at Constructor University, key influencing factors and individual resources by using mixed-method design.
- Conditions
- Social Isolation or Loneliness, Anxiety, Anxiety Depression (Mild or Not Persistent), Health Behavior
- Trial name
- CUB-HS2025 (NCT06899308)
- Testing
- questionnaire
- Where
- 2 sites in Germany
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Social Isolation or Loneliness, Anxiety
Health Surveillance at University of Applied Science Hamburg (HAW)
The aim of Health Surveillance 2025 is to analyze and describe the state of health of employees at University of Applied Science Hamburg, key influencing factors and individual resources.
- Conditions
- Social Isolation or Loneliness, Anxiety, Anxiety Acute, Anxiety Depression
- Trial name
- HAW_HS2025 (NCT07089914)
- Where
- Germany
- Volunteers
- 679 people, healthy volunteers welcome
- Sponsor
- Jacobs University Bremen gGmbH
Cancer Care Recipient, Observational Study
Bridging the Gap: Enhancing Cancer Care for Underserved Populations With the Veris Health Cancer Care Platform
The proposed study aims to optimize and validate the Veris Cancer Care Platform for the needs of medically underserved cancer patients receiving outpatient cancer therapy.
- Trial name
- NCT07396064
- Testing
- Veris Health Inc. Application
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VERIS HEALTH INC
Observational Study, Geniculate Artery
Prospective Observational Study Of Geniculate Artery Embolization For Symptomatic Knee Osteoarthritis In A Cancer Population
To explore associations with demographics/clinical factors; assess trajectories via annual follow-up; evaluate healthcare utilization and barriers; oversample >10-year survivors.
- Conditions
- Observational Study, Geniculate Artery, Embolization, Symptomatic Knee Osteoarthritis
- Trial name
- NCT07807943
- Testing
- SOC (Standard of care)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Health Adult Subjects, Exposure Occupational
French Military Firefighters to Assess Relationships Between Exposome and Health.
The aim of the study is to describe professional exposures and health events among French military firefighters (both active-duty personnel and veterans) and identify potential relationships between the exposome (the total…
- Conditions
- Health Adult Subjects, Exposure Occupational, Health Behavior, Risky, Occupational Health
- Trial name
- COMITEX-BSPP (NCT07270627)
- Where
- France
- Volunteers
- 1,811 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Observational Study
Assessing the Feasibility and Acceptability of Watching Queen of Katwe as a Role Model Intervention Among Adolescents in High Schools in Kenya
This study will test whether using the film Queen of Katwe as a role model story can help motivate and engage high school students in Kenya.
- Trial name
- NCT07072741
- Where
- 2 sites in Kenya
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Shamiri Institute
Planter Fasciitis, Observational Cohort Study
Effectiveness of Extracorporeal Shockwave in Planter Fasciitis
Extracorporeal Shockwave (ESW) is a popular, non-invasive approach that arisen in line to stimulate healing via acoustic waves targeting lesion site i.e., planter fasciitis.
- Conditions
- Planter Fasciitis, Observational Cohort Study, Effectiveness, Extracoropral Shock Wave Therapy
- Trial name
- NCT07669831
- Where
- Egypt
- Volunteers
- 175 people
- Sponsor
- Adly A Adam
Alzheimer Dementia (AD), Dementia
Clinical Risk Score Prediction for Risk of Dementia Among Late-life Population With Depression
The goal of this observational study is to learn about the ability of a point risk score prediction model, developed using electronic medical record data, to predict the risk of progression from geriatric depression to dementia…
- Conditions
- Alzheimer Dementia (AD), Dementia, Late Life Depression (LLD), Risk Scores
- Trial name
- NCT07676851
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Prospective Observational Study, Gemcitabine
Prospective Observational Study of Outcomes After Gemcitabine, Docetaxel, Melphalan, and Carboplatin With Autologous Stem Cell Transplantation in Pediatric Relapsed/Refractory Germ Cell Tumors
To collect information about treatment outcomes in pediatric and adolescent patients with relapsed/refractory germ cells tumors who receive GemDMC with an ASCT.
- Conditions
- Prospective Observational Study, Gemcitabine, Docetaxel, Melphalan
- Trial name
- NCT07662018
- Testing
- Gemcitabine (GEM), Docetaxel, Melphalan
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Phenotypic Age Acceleration, Biological Aging Marker
Phenotypic Age Acceleration (PhenoAgeAccel) for Joint Prediction of Disease Risk, Mortality Risk, Life Expectancy, and Disease-Free Healthspan in Major Chronic Diseases
The goal of this observational study is to learn about the ability of Phenotypic Age Acceleration (PhenoAgeAccel) to predict four key health outcomes in Chinese people with or at risk of major chronic diseases: the risk of…
- Conditions
- Phenotypic Age Acceleration, Biological Aging Marker, Mortality Risk Prediction, Disease Risk Prediction
- Trial name
- NCT07595094
- Testing
- No Intervention (Observational Study)
- Where
- China
- Volunteers
- 2,000,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Molecular Surveillance, Breast Cancer
Molecular Surveillance In Early Breast Cancer Using The Tumor-Informed ctDNA Assay Myriad Genetics Precise MRD Test; A Prospective Observational Multicenter Study (The MRD Molecular Surveillance Study)
To learn about changes in ctDNA during the diagnosis, treatment, and post-treatment surveillance of EBC.
- Conditions
- Molecular Surveillance, Breast Cancer, ctDNA, MRD
- Trial name
- NCT07475923
- Testing
- Blood draw for the laboratory assessment, Neoadjuvant treatment
- Sponsor
- M.D. Anderson Cancer Center
Renal Cell Carcinoma (Kidney Cancer), Renal Cell Carcinoma (RCC)
Validation of RCC Predicting Model With Emulated-target Trial
This single-center study utilizes real-world data (2012-2024) from 4700 renal cell carcinoma (RCC) patients at Peking University Third Hospital to: (1) Develop and validate a prognostic prediction model specifically for RCC…
- Conditions
- Renal Cell Carcinoma (Kidney Cancer), Renal Cell Carcinoma (RCC), Tumor Thrombus, Prognosis
- Trial name
- RCCETT (NCT07117227)
- Testing
- Model-guided adjuvant treatment, No adjuvant treatment
- Where
- China
- Volunteers
- 4,700 people
- Sponsor
- Peking University Third Hospital
Social Determinant of Health, Intracranial Aneurysms
Risk Analysis of Intracranial Aneurysm Rupture Through Social Determinants of Health
Intracranial aneurysms (IA) are arterial malformations affecting about 3% of the overall population. Rupture is the most severe complication, as it is associated with nearly 30% of death or severe disability.
- Conditions
- Social Determinant of Health, Intracranial Aneurysms, Subarachnoid Hemorrhage, Treatment Outcomes
- Trial name
- ARAMISS (NCT06866210)
- Where
- France
- Volunteers
- 1,800 people
- Sponsor
- Nantes University Hospital
Observational Study
Project VERANDA: Requirement Analysis Survey
Between 0.6% and 22.2% of the global adult male population has a sexual interest in children (SIIC), depending on evaluation methods [1].
- Trial name
- NCT07424872
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Berlin Institute of Health @ Charité
Non-Small Cell Lung Cancer, ALK
Iruplinalkib in ALK-Positive Advanced Lung Adenocarcinoma After Lorlatinib
This observational study aims to evaluate the real-world effectiveness and safety of iruplinalkib in patients with advanced ALK-positive lung adenocarcinoma who have progressed on or are intolerant to prior lorlatinib therapy.
- Conditions
- Non-Small Cell Lung Cancer, ALK, Iruplinalkib, Lorlatinib
- Trial name
- SAILOR (NCT07374614)
- Testing
- Iruplinalkib tablets
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University Shenzhen Hospital
Observational
Real-World Treatment Study of Soliris (Eculizumab)
As part of a post-approval commitment, the Korean health authority requests a study to characterize safety and effectiveness in patients who are treated with Soliris in normal clinical practice settings.
- Trial name
- SolirisPMS (NCT06448715)
- Where
- 2 sites in South Korea
- Volunteers
- 11 people
- Sponsor
- AstraZeneca
Stroke, Inpatients
A Novel Approach to Enhance True Recovery After Stroke
The purpose of this study is to elucidate pathophysiological mechanisms behind gait disturbances during the early recovery phase after hemiparetic stroke to identify targets for new treatment strategies.
- Conditions
- Stroke, Inpatients, Recovery of Function, Observational Study
- Trial name
- NCT05359367
- Testing
- Observational
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Danderyd Hospital
Clinical Characteristics and Treatment Outcomes of Malignant Tumor Cachexia, Multicenter Observational Study
A Prospective Real-World Observational Study of Nanocrystalline Megestrol Acetate in Patients With Cancer Cachexia
This study is a prospective, real-world observational study. The objective is to evaluate the effectiveness and safety of nanocrystalline megestrol acetate in patients with cancer cachexia in real-world settings.
- Trial name
- NCT07243379
- Testing
- Nanocrystalline Megestrol Acetate
- Where
- China
- Volunteers
- 495 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.