Clinical trials: Observational, open to volunteers
Muscular Dystrophies, Myopathies
Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscular Diseases
This study has the general objective of observing walking parameters during a clinical test to objectively estimate fatigue in patients with neuromuscular diseases.
- Conditions
- Muscular Dystrophies, Myopathies, Spinal Muscular Atrophy (SMA), Charcot Marie Tooth Disease
- Trial name
- NCT06666816
- Testing
- inapplicable
- Where
- 2 sites in Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Chronic Kidney Disease 5D, Secondary Hyperparathyroidism
A Observational Study to Evaluate the Efficacy and Safety of Pacitol Inj.
The purpose of this study is to evaluate the efficacy and safety of pacitol Inj.(paricalcitol) for secondary hyperparathyroidism with stage 5D chronic kidney disease (CKD 5D) receiving hemodialysis
- Trial name
- NCT06126016
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Cardiovascular Diseases, Surgery
Pressure Recording Analytical Method Parameters and Their Relationship With Hypotension in Hypertensive Patients
Perioperative anesthesiologists can benefit from easily obtainable hemodynamic variables detecting or quantifying the lack of an adequate compensatory capacity of the cardiovascular system in order to optimize patient management…
- Conditions
- Cardiovascular Diseases, Surgery, Hypotension, Hypotension on Induction
- Trial name
- PRAM-in-HYPO (NCT05960604)
- Testing
- Passive leg raising
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 660 people
- Sponsor
- Recep Tayyip Erdogan University
Ice Hockey, Grip Strength
Stability of Hand Grip Strength Across a Competitive Season in Elite Male and Female Ice Hockey Players
This study examines how hand grip strength changes over the course of a competitive ice hockey season in elite male and female players.
- Conditions
- Ice Hockey, Grip Strength, Within-season Variability
- Trial name
- NCT07570784
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Dalarna County Council, Sweden
Valvular Heart Disease
Valvular Heart Disease Registry
Patients undergoing transcatheter valvular interventions will be prospectively included into the present registry. Baseline, procedural and follow-up data will be collected and analyzed to adress various issues in the field of…
- Trial name
- NCT03488732
- Testing
- Transcatheter valvular repair or replacement
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Technical University of Munich
Cardiogenic Shock
SafeTy and Outcome of contemPorary Treatment Strategies for Cardiogenic SHOCK
International, observational registry to investigate the outcome in patients with cardiogenic shock. The primary aim of this study is to investigate the clinical outcome of patients in cardiogenic shock.
- Trial name
- STOP-SHOCK (NCT03313687)
- Where
- Germany
- Volunteers
- 2,500 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Prospective Study on Diabetes Mellitus and Its Complications in Newly Diagnosed Adult Patients
The aim of the prospective observational GDC-Study in patients with newly diagnosed diabetes mellitus aged 18-69 years at inclusion into the study is to characterize in detail the clinical, metabolical and immunological phenotype…
- Trial name
- GDC (NCT01055093)
- Where
- Germany
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Cerebral Venous Sinus Thrombosis, Deep Cerebral Vein Thrombosis
Cerebral Venous Thrombosis Cohort Study in China Mainland
This study was aimed to reveal the clinical features,natural history of the diseases and current therapeutic situations of cerebral venous thrombosis (CVT) in China mainland.
- Conditions
- Cerebral Venous Sinus Thrombosis, Deep Cerebral Vein Thrombosis, Cortical Vein Thrombosis
- Trial name
- CCC (NCT03919305)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Capital Medical University
Multiple Myeloma
Isatuximab-VRd in Transplant-Ineligible Newly Diagnosed Multiple Myeloma Patients
Primary Objective of the trial is to evaluate the efficacy and safety of Isa-VRd-based regimen in transplant-ineligible newly diagnosed multiple myeloma (TI-NDMM) patients receiving treatment in real-world clinical practice in…
- Trial name
- CHAMPION-01 (NCT07663253)
- Testing
- Isatuximab, Bortezomib, Lenalidomide
- Where
- 13 sites in China
- Volunteers
- 333 people
- Sponsor
- Shanghai Zhongshan Hospital
Large Bowel Obstruction
International Multi-center Profile of Emergency Large-Bowel Obstruction Management and Outcomes
Mechanical large-bowel obstruction is a common and high-risk emergency surgical condition with substantial variation in diagnostic evaluation, operative timing, and management strategies across institutions and healthcare…
- Trial name
- IMPEL (NCT07458867)
- Volunteers
- 500 people
- Sponsor
- European Society for Trauma and Emergency Surgery
Chronic Obstructive Pulmonary Disease, Takotsubo Cardiomyopathy
Cardiac Assessment and Takotsubo-stunning Among COPD-exacerbations In-Hospital
The goal of this prospective observational study is to investigate to what extent acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) triggers Takotsubo-stunning, and how this affects the outcome for these…
- Conditions
- Chronic Obstructive Pulmonary Disease, Takotsubo Cardiomyopathy, Acute Heart Failure
- Trial name
- CATCH (NCT06597331)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Sahlgrenska University Hospital
Polyneuropathy, Inflammatory Demyelinating, Chronic
Real-world Study of Treatment Outcomes in Chronic Inflammatory Demyelinating Polyneuropathy/Polyradiculoneuropathy (CIDP)
This study is an observational, ambispective, descriptive, non-interventional study of people with a chronic inflammatory demyelinating polyneuropathy/polyradiculoneuropathy (CIDP) diagnosis in the United States with residual…
- Trial name
- ORBIT-CIDP (NCT06968975)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Sanofi
Clinical Presentation, Natural History
Epithelioid Haemangioendothelioma Observational Study
The EHE observational study was developed to obtain a high number of datas such as clinical presentation, natural history, and treatment outcomes, cto identificate cytokines and hormones as biomarkers and generate patient-derived…
- Conditions
- Clinical Presentation, Natural History, Treatment Outcomes
- Trial name
- NCT06680401
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Apnoea, Prematurity
Automated Apnoea Detection in Preterms on Non-invasive Ventilation
The aim of this study is to monitor the frequency of apnoeas (pauses in breathing) on various methods of non-invasive respiratory support that are detected by an automated machine-learning (ML) model based on diaphragmatic…
- Trial name
- NCT07794007
- Testing
- Diaphragmatic electromyography
- Volunteers
- 30 people
- Sponsor
- King's College Hospital NHS Trust
Fabry Disease
A Study of Patients With Fabry Disease (US Specific)
This is an observational study to evaluate the effects of treatment on long-term effectiveness, safety, and health-related quality of life (HRQOL) in patients with Fabry disease, with a main focus on migalastat.
- Trial name
- NCT06906367
- Testing
- migalastat HCl, ERT
- Where
- 8 sites in United States
- Volunteers
- 450 people
- Sponsor
- Amicus Therapeutics
Diabetes, Metabolic Disorders
Observational Study for the Characterisation of Patients Affected by Any Type of Diabetes and Endocrine Disorders
The main objective of this retrospective and prospective observational register is to identify anthropometric, clinical, laboratory and/or instrumental markers of disease severity and activity in patients suffering from diabetes…
- Conditions
- Diabetes, Metabolic Disorders, Arterial Hypertension, Dyslipidemia
- Trial name
- DiabRegistry (NCT07206875)
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- IRCCS San Raffaele
Ischemic Stroke, Thrombolysis
Quantitative Net Water Uptake as a Predictor of Functional Outcomes After Intravenous Thrombolysis in Acute Ischemic Stroke International Multicenter Observational Retrospective Study
While the effectiveness of intravenous thrombolysis (IVT) decreases over time, patients show considerable variability in how quickly their ischemic core progresses.
- Trial name
- NCT07299981
- Testing
- No Interventions
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Sigmund Freud PrivatUniversitat
Crohn Disease, Colitis, Ulcerative
A Study of Continued Use of Guselkumab in Participants With Crohn's Disease and Ulcerative Colitis in Real World Setting
The purpose of this study is to find out how long a participant keeps taking guselkumab or continues with their treatment plan without stopping (treatment persistence) in participants with moderate to severe Crohn's disease (CD)…
- Trial name
- GusTaCon (NCT07746765)
- Volunteers
- 35 people
- Sponsor
- Janssen Sciences Ireland UC
Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases
Cerebral Arteriovenous Malformation With Aneurysm: Epidemiology, Clinical Features, and Prognosis
The study is a multicenter, prospective cohort study designed to assess the natural history, clinical safety and efficacy of various treatment strategies in patients with cerebral arteriovenous malformations (AVMs) and…
- Conditions
- Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases, Intra Cerebral Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT07353736
- Where
- China
- Volunteers
- 630 people
- Sponsor
- Duan Chuanzhi
Peer Bullying Intervention, Vodcast
Early Detection and Kinetics of Sepsis-Induced Coagulopathy in Severe Burn Patients
The purpose of this study is to evaluate the impact of an avatar-supported, teacher-student interactive, vodcast-based peer bullying prevention program-developed for adolescents-on students' ability to identify peer bullying…
- Conditions
- Peer Bullying Intervention, Vodcast, Students
- Trial name
- SIC-BURN-JAAM2 (NCT07905807)
- Testing
- Vodcast-Based Peer Bullying Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Selcuk University
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