Clinical trials: Observational Cohort Study
Cancer
Multi-Cancer Detection Observational Cohort Study
This study assesses the incorporation of Multi-Cancer Detection (MCD) testing, designed to detect many types of cancer, into clinical practice to understand both its use and effect in real world practice conditions.
- Trial name
- NCT06962995
- Testing
- Blood Sample, Surveys
- Where
- 3 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Anticoagulant-induced Bleeding, Dental Diseases
Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy
Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral…
- Trial name
- NOADB (NCT03124030)
- Testing
- simple dental extraction
- Where
- Italy
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Contraception
Study to Assess Outcomes in Women Undergoing Either Hysteroscopic Sterilization (Essure®) or Laparoscopic Tubal Sterilization
This study is designed to assess post-procedural outcomes for women who chose to undergo either hysteroscopic sterilization (Essure®) or laparoscopic tubal sterilization, including: Pelvic and/or lower abdominal pain Abnormal…
- Trial name
- NCT03127722
- Testing
- Blood draw, ESSURE (BAY1454032), Laparoscopic tubal sterilization
- Where
- 57 sites in United States
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Bayer
Pediatric Obstructive Sleep Apnea, Cognition
Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children
This study aims to investigate the effects of obstructive sleep apnea (OSA) on executive function and empathy development in children aged 3-12 years.
- Conditions
- Pediatric Obstructive Sleep Apnea, Cognition, Empathy, EEG
- Trial name
- OSA-EFED (NCT06850220)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Soochow University
Crohn Disease
Study of Factors and Mechanisms Influencing the Effects of Treatments in Crohn's Disease
The course of Crohn's disease (CD) varies considerably between patients, but reliable prognostic markers are not available in clinical practice.
- Trial name
- NCT04135027
- Testing
- no interventions
- Where
- 4 sites in China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Competence, Educational Problems
Teleteaching on Clinical Procedural Skills
This study aims to develop a model of teleteaching and teleassessment for clinical procedural skills, consisted of teleteaching design making and teleteaching intervention was conducted in September 2020 - February 2021 at a…
- Trial name
- NCT05467969
- Testing
- Teleteaching of procedural skills through the online multiscreen display teleconference platform
- Where
- Indonesia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Pancreatic Adenocarcinoma
Panc CA Risk Model & Biomarker Testing In High-Risk Cohort
The purpose of this study is to test a double screening strategy for pancreatic cancer, based on a model developed using patient medical records.
- Trial name
- NCT05287347
- Testing
- Blood Specimen
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Peer Bullying Intervention, Vodcast
Early Detection and Kinetics of Sepsis-Induced Coagulopathy in Severe Burn Patients
The purpose of this study is to evaluate the impact of an avatar-supported, teacher-student interactive, vodcast-based peer bullying prevention program-developed for adolescents-on students' ability to identify peer bullying…
- Conditions
- Peer Bullying Intervention, Vodcast, Students
- Trial name
- SIC-BURN-JAAM2 (NCT07905807)
- Testing
- Vodcast-Based Peer Bullying Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Human Immunodeficiency Virus, Obesity
Adipose Tissue and Immune Activation in HIV
The prevalence of HIV-associated wasting declined dramatically with the introduction of effective antiretroviral therapy (ART), but as patients survive longer on treatment the proportion of overweight (body mass index [BMI] >25…
- Trial name
- AIAC (NCT04439448)
- Testing
- dual-energy X-ray absorptiometry (DEXA) scan, Carotid and branchial artery ultrasound, 2-hour oral glucose tolerace test
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Anticoagulant-induced Bleeding, Periodontal Diseases
Evaluation of the Intra- and Post- Operative Bleeding After Periodontal Debridement in Direct Anticoagulant Patients
Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral…
- Trial name
- NOADB_db (NCT03124004)
- Testing
- periodontal debridement
- Where
- Italy
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Myotonic Dystrophy Type 1 (DM1)
A Registered Observational Cohort Study of Myotonic Dystrophy Type 1
Myotonic dystrophy type 1 (DM1) is the most common form of muscular dystrophy.There is little phenotype and genetic data for Chinese DM1 patients.
- Trial name
- NCT06979024
- Testing
- Triplet-primed PCR or Long-read sequencing
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Altitude Hypoxia, Neonatal Encephalopathy
Neonatal Electrical Activity at Different Altitude Levels
In this study, the objective is to compare neonatal cerebral electrical activity within 3 days after birth across different altitude areas using amplitude-integrated electroencephalography (aEEG), and establish reference value…
- Trial name
- NCT05966714
- Testing
- aEEG
- Where
- 2 sites in China
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Dental Anxiety
Measuring and Evaluating the Changes in Anxiety Levels of Children With Repetitive Sessions of Dental Treatments
Dental anxiety is defined as the fear of terrible events during dental treatment and the loss of control.Anxiety may be related to adaptation of the patient to external factors in environment, so the adaptation of the pediatric…
- Trial name
- NCT04967300
- Testing
- Dental treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Zika Virus Disease (Disorder)
Zika in Infants and Pregnancy (ZIP)
The overall objective of this multisite, multicountry Zika in Infants and Pregnancy (ZIP) study is to assess the strength of the association between Zika virus infection (ZIKV) during pregnancy and adverse maternal/fetal outcomes…
- Trial name
- NCT02856984
- Where
- 10 sites in Brazil, Colombia and 4 more
- Volunteers
- 6,461 people, healthy volunteers welcome
- Sponsor
- RTI International
HIV Preexposure Prophylaxis
The SwissPrEPared Study
Nested within the SwissPrEPared Program, the "SwissPrEPared Study" - a large, multicentric, nation-wide cohort study - aims to longitudinally follow individuals asking for PrEP prescription over a period of 3 years.
- Trial name
- NCT03893188
- Where
- 41 sites in Switzerland
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Chronic Cough (CC)
China Chronic Cough Registry: a Multicenter, Prospective, Observational Study
The aim is to establish a national clinical database and biobanks for chronic coughers. Through real-world chronic cough case registry and follow-up studies, we will explore the clinical phenotypes and molecular subtypes of…
- Trial name
- NCT06862362
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
COVID-19
Detection of Anti-COVID-19 Antibody Levels in an Hospital Population
COVID-19 (SARS-CoV-2) infection in health professionals represent a significant criticality both for the risk of spreading the disease and for the organizational aspects that follow.
- Trial name
- NCT04387929
- Testing
- Detection of anti-COVID-19 antibody level
- Where
- Italy
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
α-synucleinopathy
A Registered Cohort Study on α-Synucleinopathy
α-Synucleinopathy is a cluster of neurodegenerative disease with motor and non-motor symptom. The data to be collected is intended to help healthcare providers make important medical decisions concerning α-synucleinopathy…
- Trial name
- NCT05527067
- Testing
- Data collection
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Charcot-Marie-Tooth Disease
A Registered Cohort Study on Charcot-Marie-Tooth Disease
The aim of the study is to analyze the natural history data data from Charcot-Marie-Tooth disease and related disorders in China, to assess the clinical, genetic, epigenetic features of patients with Charcot-Marie-Tooth disease…
- Trial name
- NCT04010188
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Ning Wang, MD., PhD.
Infertile Women Undergoing IVF or ICSI
Observational Study to Develop Dosing Chart
To confirm the predictors based on patient specific characteristics and ovarian response and develop dosing chart when Follitrope™ PFS is administered to infertility women patients.
- Trial name
- NCT04227171
- Where
- South Korea
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- LG Chem